Advertise on podcast: Ask The Expert Presents Hemophilia on Balance

Season One comes to a thrilling close on this finale of Ask the Expert! Join Amy B as she brings back all of our amazing guests—Dr. Tammy Singleton, Dr. Mark Reding, Dr. Amy Dunn, Dr. Ben Samelson Jones, Dr. Patrick Ellsworth, and Dr. Janice Stabler—for a fast-paced, unforgettable review of everything we've explored this year. We're diving into the clotting cascade, rebalancing agents, inhibitors, women in care, and safety—tying together the breakthroughs, the debates, and the "aha" moments that defined this season. If you've ever wondered where bleeding disorder care is headed, this finale is your front-row seat. Listen, celebrate, and get hyped!  Presenting Sponsor: Presented by Sanofi   Show Notes:   Rich's Story Join Rich as he discusses how hemophilia has impacted his ability to travel and live an active lifestyle. He highlights how hemophilia affects far more than just physical health and shares his journey of overcoming barriers to be able to safely travel internationally, fly fish, garden, and more.   Click here to watch his story:    https://www.youtube.com/watch?v=ihEvFywE43E&list=PLmqBxf22n4lNK82h3QZ-9YlpIjYdzDOer&index=8 Join Kevin as he shares about his journey with hemophilia and the hurdles he faced in communicating with friends, family, and healthcare providers about his condition. He highlights how hemophilia affects far more than just physical health — and why honest, open conversations that focus on the full patient experience, not just symptoms, are so essential. Click here to watch his story: https://www.youtube.com/watch?v=3v1cCTbhClA&list=PLmqBxf22n4lNK82h3QZ-9YlpIjYdzDOer&index=5   Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.  Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

In this episode of Ask the Expert, Amy B. dives into the future flow of hemostasis research, exploring the cutting-edge therapies shaping bleeding disorder care. Join Drs. Patrick Ellsworth, Janice Staber, and Ben Samelson-Jones as they break down rebalancing agents, RNA therapies, and patient-driven discoveries that are guiding smarter, more precise treatment. From understanding the coagulation cascade to creating new pathways for clotting, we explore what's next in research and how these innovations are transforming lives. Presenting Sponsor: Presented by Sanofi   Show Notes:   Mark's Story Join Mark as he shares about his experience living with hemophilia, including the impact it had on building and maintaining relationships throughout grade school, college, dating, and raising his family. Mark also highlights how shared decision making with his healthcare providers, and strong family and caregiver support in those decisions, can make all the difference when it comes to managing the daily challenges of hemophilia.   Click here to watch his story: https://www.youtube.com/watch?v=tQ8oeM0zL24&list=PLmqBxf22n4lPMpAfLe4yv8haC6Ejcp1XL&index=8   #MyHemophiliaTruth. Real stories. Powered by Sanofi. It's time to consider the whole experience when it comes to managing hemophilia and change the conversation. Explore the full story at www.myhemophiliatruth.com   Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.  Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

Join host Amy Board as we continue to dive into the evolving world of bleeding disorder treatments. This episode of Ask the Expert explores how emerging therapies—like rebalancing and non-factor agents—are tested, monitored, and kept safe. With insights from Drs. Mark Redding, Janice Stabler, and Tammy Singleton, we break down the complexities of dosing, breakthrough bleeds, and surgical planning, showing why safety checks and open communication with your care team are more critical than ever. Learn how these therapies fine-tune the clotting system without replacing missing factors and why staying informed is key to confident, safe care. Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network. Presented by Sanofi #MyHemophiliaTruth. Real stories. Powered by Sanofi. It's time to consider the whole experience when it comes to managing hemophilia and change the conversation. Explore the full story at www.myhemophiliatruth.com The Bigger Picture in Hemophilia B:  Hemophilia A and hemophilia B are different bleeding disorders with unique pathologies and clinical features.1 Due to the distinct behavior of factor IX, multiple PK parameters should be considered when assessing bleed prevention. Learn how a broader view of PK may influence evaluation of treatment and management for patients with hemophilia B.2,3 Learn more at thebiggerpictureinhemb.com   Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?  → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

In this episode of Ask the Expert, we focus on women with bleeding disorders — a group that has historically been overlooked in research and clinical care. Heavy menstrual bleeding, mild and moderate hemophilia, and von Willebrand disease have often gone underdiagnosed or mischaracterized, leaving many women without the care they need. Amy Board sits down with leading hematology experts to discuss emerging therapies, including replacement and rebalancing agents, the science behind how they work, and why representation in clinical trials matters. We also explore the challenges women face in accessing treatment and the opportunities these new therapies provide for improving care. This episode highlights both the progress being made and the work still ahead to ensure all patients are seen, heard, and treated effectively. Presenting Sponsor: Presented by Sanofi Kevin's Story Join Kevin as he shares about his journey with hemophilia and the hurdles he faced in communicating with friends, family, and healthcare providers about his condition. He highlights how hemophilia affects far more than just physical health — and why honest, open conversations that focus on the full patient experience, not just symptoms, are so essential.   Click here to watch his story: https://www.youtube.com/watch?v=3v1cCTbhClA&list=PLmqBxf22n4lNK82h3QZ-9YlpIjYdzDOer&index=5 Sanofi's Global Hemophilia Survey uncovers significant care gaps and emotional challenges faced by patients and caregivers. Learn how improving health literacy and fostering better patient-provider communication are essential to addressing these inequities. Explore the findings and see how Sanofi is driving health equity for the hemophilia community. Explore the survey findings here: Global Hemophilia Survey Page. Show Notes:   Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

This week on Ask The Expert, the script is being flipped for patients with inhibitors and rare factor deficiencies! For years, treatment options were scarce—or even nonexistent. Now, rebalancing agents are changing the game, restoring clotting balance without relying on replacement factors. Amy is joined by Dr. Ben Samuelson Jones, Dr. Tammy Singleton, Dr. Patrick Ellsworth, and Dr. Mark Redding as they take listeners on a journey through how these groundbreaking therapies are bringing new hope to people with hemophilia B, inhibitors, and ultra-rare bleeding disorders. From inhibitors to ultra-rare conditions, this episode dives into the science, stories, and breakthroughs that are reshaping the future of bleeding disorder care. Don't miss it! Presenting Sponsor: Presented by Sanofi Join Shellye as she shares her inspiring journey as a woman living with hemophilia. After years of unanswered questions, her diagnosis highlights the critical role of health literacy in bridging care gaps. Through advocacy, Shellye raises awareness and empowers underserved communities. Watch her story and see how health literacy can break barriers and transform lives. Click here to watch her story: Sanofi – See Hemophilia Through My Eyes: Women & Girls For too long, women and girls who bleed have been dismissed. Left out of the narrative. Ignored by the system. But not anymore. In our new film, "Dismissed," meet Isabelle—a 15-year-old with hemophilia who's using her voice to uplift the unheard. Alongside her are four powerful stories of women challenging what's "normal" and demanding recognition, care, and justice. This is more than a film. It's a movement. 📽️ Watch and share the trailer now. Learn more at http://dismissedfilm.com/ Show Notes:   Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

Rev your engines and put the pedal to the metal on a wild ride through the clotting cascade! Amy Board and a pit crew of medical experts take you on an uproarious recap journey through the first six episodes, using engines, dominoes, and treasure maps to drive their points home. But hold onto your helmets—there's fresh and exciting science just around the corner. It's a thrill ride through bleeding disorder mysteries—whether you're an old pro or new on the scene, this recap episode is the perfect pit stop before the high-speed chase into new discoveries.  Presenting Sponsor: Presented by Sanofi Join Shellye as she shares her inspiring journey as a woman living with hemophilia. After years of unanswered questions, her diagnosis highlights the critical role of health literacy in bridging care gaps. Through advocacy, Shellye raises awareness and empowers underserved communities. Watch her story and see how health literacy can break barriers and transform lives. Click here to watch her story: Sanofi – See Hemophilia Through My Eyes: Women & Girls For too long, women and girls who bleed have been dismissed. Left out of the narrative. Ignored by the system. But not anymore. In our new film, "Dismissed," meet Isabelle—a 15-year-old with hemophilia who's using her voice to uplift the unheard. Alongside her are four powerful stories of women challenging what's "normal" and demanding recognition, care, and justice. This is more than a film. It's a movement. 📽️ Watch and share the trailer now. Learn more at http://dismissedfilm.com/ Show Notes: Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network. Presented by Sanofi  Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

In this episode of Ask the Experts, host Amy Board breaks down one of the most exciting developments in bleeding disorders treatment — rebalancing agents. Think of your body's clotting system like a seesaw: when everything's working right, it's balanced. But in bleeding disorders, the scale tips. Instead of adding what's missing (like clotting factors), rebalancing agents work by removing what's getting in the way — helping to restore that balance in a totally new way. Amy is joined by Dr. Ben Samuelson Jones, Dr. Patrick Ellsworth, and Dr. Tami Singleton for a deep dive into how these therapies work, how they were inspired by what's already happening naturally in the body, and what makes them so promising. From TFPI antibodies to small interfering RNA treatments like Fitusiran, these cutting-edge approaches could transform care for many. The experts also discuss the crucial role of patient participation in ongoing studies and why your voice matters in shaping the future of treatment. It's a hopeful, eye-opening conversation about how innovation is changing the game for bleeding disorders — and what comes next. Presenting Sponsor: Presented by Sanofi   For too long, women and girls who bleed have been dismissed. Left out of the narrative. Ignored by the system. But not anymore.   In our new film, "Dismissed," meet Isabelle—a 15-year-old with hemophilia who's using her voice to uplift the unheard. Alongside her are four powerful stories of women challenging what's "normal" and demanding recognition, care, and justice.   This is more than a film. It's a movement. 📽️ Watch and share the trailer now. Learn more at http://dismissedfilm.com/    Sanofi's Global Hemophilia Survey uncovers significant care gaps and emotional challenges faced by patients and caregivers. Learn how improving health literacy and fostering better patient-provider communication are essential to addressing these inequities. Explore the findings and see how Sanofi is driving health equity for the hemophilia community. Explore the survey findings here: Global Hemophilia Survey Page.   Show Notes:   Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

In this episode, Amy trades medical jargon for construction metaphors as she takes us on a journey through hemostasis, the body's natural way of stopping a bleed. But what happens when the repair crew is understaffed—or missing entirely? That's where factor replacement therapy comes in. Amy and our experts explain how it works, why timing matters, and how it helps people with bleeding disorders live safer, fuller lives. Whether you're new to the community or a longtime listener, you'll walk away with a better understanding of how the body works—and why treatment makes such a big difference.   Presenting Sponsor: Presented by Sanofi   #MyHemophiliaTruth. Real stories. Powered by Sanofi. It's time to consider the whole experience when it comes to managing hemophilia and change the conversation. Explore the full story at www.myhemophiliatruth.com The Bigger Picture in Hemophilia B:  Hemophilia A and hemophilia B are different bleeding disorders with unique pathologies and clinical features.1 Due to the distinct behavior of factor IX, multiple PK parameters should be considered when assessing bleed prevention. Learn how a broader view of PK may influence evaluation of treatment and management for patients with hemophilia B.2,3 Learn more at thebiggerpictureinhemb.com  1. Castaman G, Matino D. Haematologica. 2019;104(9):1702-1709. 2. Dolan G, Benson G, Duffy A, et al. Blood Rev. 2018;32(1):52-60.  3. Mann DM, Stafford KA, Poon M-C, Matino D, Stafford DW. Haemophilia. 2021;27(3):332-339. Show Notes: Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

On this exciting episode of Ask the Expert, join Amy as we delve into the fascinating world of blood clotting and anticoagulant therapy. We'll explore the clotting process with fun and relatable party analogies, featuring expert insights from Dr. Ben and Dr. Patrick. Discover how vital components like Protein C, Protein S, antithrombin, and TFPI work together to maintain the body's delicate clotting balance, and learn about the latest advancements in hemophilia treatment in this engaging and educational deep dive! Presenting Sponsor: Presented by Sanofi #MyHemophiliaTruth. Real stories. Powered by Sanofi. It's time to consider the whole experience when it comes to managing hemophilia and change the conversation. Explore the full story at www.myhemophiliatruth.com Mark's Story Join Mark as he shares about his experience living with hemophilia, including the impact it had on building and maintaining relationships throughout grade school, college, dating, and raising his family. Mark also highlights how shared decision making with his healthcare providers, and strong family and caregiver support in those decisions, can make all the difference when it comes to managing the daily challenges of hemophilia. Click here to watch his story: https://www.youtube.com/watch?v=tQ8oeM0zL24&list=PLmqBxf22n4lPMpAfLe4yv8haC6Ejcp1XL&index=8   Show Notes: Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network. Presented by Sanofi  Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?  → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

Dive into the crucial roles of Factor VIII, Factor IX, and thrombin in the blood clotting process. Hosts Amy and Patrick introduce expert Dr. Benjamin J. Samelson-Jones to discuss the interplay between these factors, including how they activate each other and form clots. Featuring insights from Dr. Mark Reding on the myriad functions of thrombin, this episode breaks down complex biochemical processes into easily digestible information for all listeners. Perfect for anyone looking to understand hemostasis and thrombosis better.   Presenting Sponsor: Presented by Sanofi   Show Notes: Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

This episode of "Ask the Expert" titled "Striking the Right Balance – Why Does it Matter in Hemophilia Treatment?" delves into the concept of rebalancing in hemophilia treatment. Hosted by Amy Bord, the episode features expert insights from Dr. Ben Samuelson Jones, Dr. Patrick Ellsworth, and Dr. Mark Redding. They explain how hemophilia treatments can go beyond merely replacing missing clotting factors by using rebalancing agents that adjust anticoagulant proteins. The conversation emphasizes the importance of understanding the delicate balance between bleeding and clotting in the body, why this knowledge is vital for treatment decisions, and introduces the new class of medications called rebalancing agents. The episode also highlights the role of individual bleeding tendencies in determining appropriate treatments.   Presenting Sponsor: Presented by Sanofi Show Notes: Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

In this episode of 'Ask the Expert,' host Amy Board dives into the clotting cascade and explains how our blood clots. Alongside experts Dr. Ben Samuelson Jones, Dr. Amy Dunn, Dr. Mark Redding, and Dr. Patrick Ellsworth, Amy unpacks the complexity of the hemostatic system, discusses new treatments for hemophilia, and explores both the clotting and regulating parts of this vital bodily function. Tune in to understand how the clotting system works and the exciting potential of new therapies in the field.   Presenting Sponsor: Presented by Sanofi Show Notes: Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

Ask the Expert is back with a twelve-episode deep dive into the evolving landscape of a groundbreaking new class of therapies in hemophilia treatment—rebalancing agents. Through expert insights and discussions, our new season, Hemophilia: On Balance, unpacks complex science to make it accessible and relevant to the hemophilia community. Episodes will be released monthly starting March 2025, with bonus content dropping weekly. Whether you're a patient, caregiver, or healthcare provider, Ask the Expert empowers you to understand the latest advances and make informed decisions about hemophilia care.   Presenting Sponsor: Presented by Sanofi   Show Notes: Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.   Presented by Sanofi   Subscribe to the Ask the Expert    Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community?    → BloodStreamMedia.com → BloodStream Media on Facebook  → BloodStream Media on Instagram  → BloodStream Media on LinkedIn  

Our guest for this month is Believe Limited CEO and Bloodstream host, Patrick James Lynch. Ask the Expert is headed in a new direction and Patrick joins us to share what the future will hold for the Bloodstream Media network. Even though this will be the final episode of Ask the Expert, we are excited to announce the new path for our expert interviews, because they're not going away! Listen in with Patrick and Amy as they share the new and exciting things coming from Bloodstream Media! Welcome to Episode 40, or To the Future! The final episode of the Ask The Expert Podcast!    Check out all the podcast offerings from Bloodstream Media: https://www.bloodstreammedia.com/ Register for the virtual Bleeding Disorder Conference here: https://events.hemophilia.org/ehome/bleedingdisordersconference/about/?&_ga=2.12224756.1785968952.1589565712-1855623951.1578586058  

Join us for our "Get to Know the Expert" episode of Ask the Expert! Having the opportunity to know our national leaders in a personal way is an honor and a treat for any community. Join us on today's episode to get to know CEO the National Hemophilia Foundation, Dr. Len Valentino! We'll learn how Dr. Valentino got his start, what lessons he learned from treating patients, his interests in the global disparity of care, and his thoughts of the Michael Jordan documentary, The Last Dance! Join us to get to know Dr. Valentino a little better! Welcome to Episode 39 - or our Get to Know the Expert Episode - of the Ask The Expert Podcast!    Check out the weekly webinar series provided by the National Hemophilia Foundation here: The National Hemophilia Foundation: https://www.hemophilia.org/ Register for the virtual Bleeding Disorder Conference here: https://events.hemophilia.org/ehome/bleedingdisordersconference/about/?&_ga=2.12224756.1785968952.1589565712-1855623951.1578586058