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Michelle A. Detry, PhD, Berry Consultants LLC, discusses The Intention-to-Treat Principle: How to Assess the True Effect of Choosing a Medical Treatment with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: The Intention-to-Treat Principle

Roderick Little, PhD, University of Michigan School of Public Health Departments of Epidemiology & Biostatistics discusses Pattern-Mixture Models for Missing Data with Roger J. Lewis, MD, PhD, statistical editor for JAMA. Related Content: Pattern-Mixture Models for Missing Data

Kert Viele, PhD, director and senior statistical scientist at Berry Consultants, discusses "Interpretation of Clinical Trials That Stopped Early" with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Interpretation of Clinical Trials That Stopped Early

Natalie Exner Dean, PhD, Associate Professor, Rollins School of Public Health, Emory University, discusses Test-Negative Study Designs for Evaluating Vaccine Effectiveness with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Test-Negative Study Designs for Evaluating Vaccine Effectiveness

Steve A. Webb, MBBS, MPH, PhD, professor, Royal Perth Hospital, The University of Western Australia discusses Platform Clinical Trials for the Efficient Evaluation of Multiple Treatments with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Platform Clinical Trials for the Efficient Evaluation of Multiple Treatments How to Use and Interpret the Results of a Platform Trial

Kendra D. Sims, PhD, postdoctoral associate in Epidemiology, Boston University, discusses Tipping Point Analysis: Assessing the Potential Impact of Missing Data with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Tipping Point Analysis

Edward C. Norton, PhD, University of Michigan Health Management and Policy, discusses Instrumental Variables and Heterogeneous Treatment Effects with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Instrumental Variables and Heterogeneous Treatment Effects

Jody D. Ciolino, PhD, Northwestern University, Feinberg School of Medicine discusses Factorial Clinical Trial Designs with JAMA Statistical Editor Roger J. Lewis, MD, PhD Related Content: Factorial Clinical Trial Designs Reporting of Factorial Randomized Trials

Maria Mori Brooks, PhD, University of Pittsburgh School of Public Health, discusses "Assessing Unexpected Circumstances That Lead to Modifications in Clinical Trial Design, Conduct, or Analysis" in the JAMA Guide to Statistics and Methods series, with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Assessing Unexpected Circumstances That Lead to Modifications in Clinical Trial Design, Conduct, or Analysis

Lars W. Andersen, MD, MPH, PhD, DMSc, Aarhus University, discusses collider bias in the JAMA Guide to Statistics and Methods series with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Collider Bias

John M. Lachin, ScD, Biostatistics Center, George Washington University, discusses Nonparametric Statistical Analysis with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Nonparametric Statistical Analysis

Andrew D. Althouse, PhD, University of Pittsburgh School of Medicine discusses The Use of Historical Controls in Clinical Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: The Use of Historical Controls in Clinical Trials

Barbara Wendelberger, PhD, Berry Consultants, discusses Futility in Clinical Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Futility in Clinical Trials

William J. Meurer, MD, MS, University of Michigan Medical School, discusses Interim Analyses During Group Sequential Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Interim Analyses During Group Sequential Clinical Trials

Jerome I. Rotter, MD, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Department of Pediatrics, Harbor-UCLA Medical Center, discusses Genome-Wide Association Studies with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Genome-Wide Association Studies