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Heart disease can develop without symptoms, and cholesterol results may miss the risk. Dr. Greg Jones speaks with Campbell Rogers, MD, Chief Medical Officer at HeartFlow, about how coronary CT angiography (CCTA) and AI-powered plaque analysis help assess coronary artery disease. Dr. Rogers explains FFR-CT blood flow analysis, LDL cholesterol, lipoprotein(a) [Lp(a)], and calcified versus non-calcified plaque. They discuss why a zero calcium score may not show all plaque and why a 70% blockage may not need a stent. They also cover advanced lipid testing, CT contrast, who may benefit from cardiac imaging, and myths about cholesterol and statins. Learn what these tests reveal about heart attack risk and what to discuss with your doctor. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 📌 About Campbell Rogers, MD Campbell Rogers, MD, is the Chief Medical Officer at HeartFlow, where he helps advance non-invasive technologies for assessing coronary artery disease through cardiac imaging, blood flow assessment, and plaque analysis. His work spans cardiovascular diagnostics, medical devices, research, and clinical care. Previously, Dr. Rogers served as Chief Scientific Officer and Global Head of Research and Development at Cordis Corporation and Johnson & Johnson, and as an Associate Professor of Medicine at Harvard Medical School and the Harvard-MIT Division of Health Sciences and Technology. He directed cardiac catheterization and experimental cardiovascular interventional laboratories at Brigham and Women’s Hospital. He earned his A.B. from Harvard College and his M.D. from Harvard Medical School. 📌 Learn More About Campbell Rogers, MD Website: https://www.heartflow.com/ LinkedIn: https://www.linkedin.com/in/campbell-rogers-67952938 📌 Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK 🔗 Want to learn more? Check these resources: American Heart Association – Cardiac Computed Tomography Angiography (CCTA): https://www.heart.org/en/health-topics/heart-attack/diagnosing-a-heart-attack/cardiac-computed-tomography American Heart Association – Lipoprotein(a) and Heart Health: https://www.heart.org/en/health-topics/cholesterol/genetic-conditions/lipoprotein-a-risks NIH/NHLBI – Heart Tests (Coronary Calcium Scan): https://www.nhlbi.nih.gov/health/heart-tests 🔬 Timestamps Introduction and Dr. Rogers’ path to HeartFlow (00:00 - 03:48) Why heart disease can develop without symptoms (03:48 - 05:38) LDL particles, plaque buildup, and inflammation (05:38 - 08:45) Why total cholesterol does not tell the full story (08:45 - 12:57) How HeartFlow and coronary CT angiography work (12:57 - 15:39) Understanding CT-derived fractional flow reserve (FFR-CT) (15:39 - 18:20) Why a 70% blockage does not always mean a stent (18:20 - 20:44) How HeartFlow analyzes coronary plaque (20:44 - 22:44) Calcified vs. non-calcified plaque and heart attack risk (22:44 - 24:50) What a zero coronary calcium score really means (24:50 - 27:12) CT contrast, kidney function, and imaging safety (27:12 - 30:33) Who might benefit from additional cardiac imaging? (30:33 - 34:02) Heart disease risk in firefighters and former athletes (34:02 - 36:06) Lipoprotein(a), advanced lipids, and cardiovascular risk (36:06 - 39:18) Kick It or Keep It: cholesterol and heart health myths (39:18 - 43:26) 🔍Want to Learn More? (Research Citations) Here is the science discussed in today's episode: PMID: 19081406 Lipid Levels in Hospitalized CAD Patients PMID: 34773460 ApoB Lipoproteins and Heart Attack Risk PMID: 26330417  FFR-CT: Clinical Outcomes in Suspected CAD

Dr. Jones discusses using innovative therapies for patient healing, specifically noting benefits like reduced inflammation and boosted hair growth. He highlights the science behind GHK-Cu, especially its positive effects on skin care and collagen synthesis. Learn more about how GHK-Cu enhances skin.CHAPTERS00:00 Introduction to GHK Copper00:46 What Is GHK Copper and How It Works01:34 Skin Health and Anti-Aging Benefits02:15 Healing and Tissue Repair03:08 Hair Growth and Restoration03:42 Antioxidant and Anti-Inflammatory Effects04:17 Longevity and Gene Activation05:07 How GHK Copper Is Used Clinically06:16 Final Thoughts and Takeaway Check out the GHK-Cu Hair and Skin Bundle on Dr. Jones's Supplement Store and get 10% off your first order when you join the email list: Connect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/ 📺 YouTube: https://www.youtube.com/@DrGregJonesNMD📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. ---____________________________The information provided in this video is solely for educational and informational purposes. It is not intended to provide medical advice or to diagnose, treat, cure, or manage any health condition. Viewing this content does not establish or imply a doctor–patient relationship. You should not rely on this content as a substitute for consultation with a licensed healthcare professional regarding your own specific medical questions or health concerns. Always seek the advice of your physician or other qualified healthcare provider before starting, stopping, or changing any medication, supplement, treatment, or lifestyle program. Never disregard professional medical advice or delay seeking it because of something you have seen in this video. If you believe you may be experiencing a medical emergency, call 911 or your local emergency number immediately.

Sleep optimization is one of the most important foundations for energy, focus, recovery, brain health, and long-term wellness. In this episode, Dr. Greg Jones talks with Dr. Angela Holliday-Bell, a board-certified physician and certified sleep specialist, about what actually works for improving sleep quality. Dr. Holliday-Bell explains the difference between insomnia and sleep deprivation, why sleep can become harder with age, and how deep sleep supports recovery, cognition, and overall performance. They also discuss sleep tracking, “sleep maxing,” orthosomnia, brain fog, waking up at 3 a.m., and why sleep apnea is often missed. The conversation covers practical sleep strategies, bedtime routines, scrolling before bed, alcohol, exercise, white noise, reading, magnesium, melatonin, CBT-I, and when sleep medications may not be the best first step. If you want better sleep, sharper focus, and more restorative recovery, this episode offers practical tools you can start using tonight. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 📌 About Dr. Angela Holliday-Bell Dr. Angela Holliday-Bell is a board-certified physician, certified sleep specialist, speaker, author, and founder of The Solution is Sleep. After overcoming her own struggle with insomnia, she dedicated her work to helping people improve health, performance, and well-being through better sleep. Her work has been featured on Dr. Phil, ABC News, WGN, the Sleep Foundation, Women’s Health, Well+Good, and TODAY. She helps organizations improve employee wellness, resilience, and performance through evidence-based sleep strategies. Her clients include KPMG, Microsoft, and the FDA. 📌 Learn More About Dr. Holliday-Bell Website: https://thesolutionissleep.com/ LinkedIn: https://www.linkedin.com/in/drhollidaybell/ Instagram: https://www.instagram.com/thesleep_md 📌 Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK 🔗 Want to learn more? Check these resources: Orthosomnia and sleep tracking anxiety: https://pubmed.ncbi.nlm.nih.gov/27855740/  Ashwagandha and melatonin effects on sleep quality: https://pubmed.ncbi.nlm.nih.gov/42029558/  NHLBI/NIH — Insomnia diagnosis and sleep testing: https://www.nhlbi.nih.gov/health/insomnia/diagnosis  Sleep Foundation — Orthosomnia and sleep tracker anxiety: https://www.sleepfoundation.org/orthosomnia  🔬 TimestampsIntroduction and Dr. Holliday-Bell’s insomnia journey (00:00 - 02:53)Insomnia vs. sleep deprivation (02:53 - 05:10)Why sleep gets harder with age (05:10 - 07:34)Sleep stages and why deep sleep matters (07:34 - 11:43)Sleep, brain fog, and cognitive performance (11:43 - 15:14)Sleep maxing, wearables, and sleep anxiety (15:14 - 21:32)Hidden signs of sleep apnea (21:32 - 25:31)What to do when you wake up at 3 a.m. (25:31 - 31:13)Why scrolling before bed hurts sleep (31:13 - 33:30)Sleep myths: alcohol, exercise, white noise, and reading (33:30 - 37:41)Magnesium, melatonin, and sleep supplements (37:41 - 43:43)CBT-I and when sleep medications are not the answer (43:43 - 49:50)One habit that can improve your sleep tonight (49:50 - 52:00)

Functional Diagnostic Nutrition helps explain why your lab results may look “normal” even when you still struggle with fatigue, poor sleep, digestive issues, hormone imbalances, inflammation, or poor metabolic health. In this episode, Dr. Greg Jones talks with Jennifer Woodward, MS, FDN-P, about how functional testing can uncover hidden patterns that standard lab ranges may miss. Jennifer shares her personal health journey and explains how Functional Diagnostic Nutrition focuses on root causes instead of symptom management. They discuss blood sugar, fasting glucose, inflammation, cholesterol, gut health, functional lab ranges, continuous glucose monitors, peptides, and why lifestyle foundations should come before advanced therapies. If you want to better understand your lab work, optimize your hormones, support longevity, or take a more proactive approach to wellness, this episode offers practical insight. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 📌 About Jennifer Woodward, MS, FDN-P Jennifer Woodward is a Functional Diagnostic Nutrition Practitioner, Board Certified Functional Wellness Coach, and holds a Master of Science in Integrative Nutrition. She helps women optimize hormones, metabolism, gut health, and longevity through functional lab testing, personalized nutrition, and lifestyle strategies. Jennifer has worked with more than 1,400 women, previously served as Director of Education for Functional Diagnostic Nutrition, and has taught advanced functional lab interpretation to healthcare practitioners. 📌 Learn More About Jennifer Woodward Website: https://jenniferwoodwardnutrition.com Instagram: https://www.instagram.com/jenniferwoodwardnutrition Podcast: Peptides for Women 📌 Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK 🔗 Authoritative Resources & Further Reading • NIDDK – Diabetes & Prediabetes Tests: https://www.niddk.nih.gov/health-information/professionals/clinical-tools-patient-management/diabetes/diabetes-prediabetes • CDC – Continuous Glucose Monitors: https://www.cdc.gov/diabetes/treatment/continuous-glucose-monitors.html • NIDDK – Why Screen for Prediabetes: https://www.niddk.nih.gov/health-information/professionals/clinical-tools-patient-management/diabetes/game-plan-preventing-type-2-diabetes/prediabetes-screening-how-why/why-screen-for-prediabetes  🔬 Timestamps Introduction and Jennifer Woodward’s health journey (00:00 - 05:28) What Functional Diagnostic Nutrition Practitioners do (05:28 - 07:37) Why normal labs do not always mean optimal health (07:37 - 10:22) Blood sugar, fasting glucose, and CGMs (10:22 - 17:10) Inflammation, CRP, cholesterol, and heart health (17:10 - 24:13) Longevity and the most important lab markers (24:13 - 30:38) The HIDDEN framework for whole-body health (30:38 - 34:57) Gut testing, GI-MAP, SIBO, and food sensitivities (34:57 - 41:46) Peptides and why lifestyle foundations come first (41:46 - 47:40) Where to learn more about Jennifer Woodward (47:40 - 50:12)

The gut-brain axis plays a major role in mood, brain fog, inflammation, digestion, metabolism, and long-term health. In this episode, Dr. Greg Jones sits down with naturopathic physician Dr. Jennifer Stagg to explain the gut-brain connection, why the microbiome matters, and how gut health can influence anxiety, cravings, energy, and overall wellness. Dr. Stagg explains how stress can disrupt the gut microbiome and how the vagus nerve helps connect the digestive system with the nervous system. The conversation also explores leaky gut, butyrate, probiotics, digestive symptoms, and why gut problems do not always show up in obvious ways. If you are dealing with digestive issues, brain fog, anxiety, low energy, chronic inflammation, food cravings, or simply want to better understand the gut-brain connection, this episode offers science-based insight into how to support a healthier microbiome and improve resilience. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 📌 About Dr. Jennifer Stagg Dr. Jennifer Stagg is a naturopathic physician, clinical researcher, author, and founder of Whole Health Wellness Center in Connecticut. She holds degrees in biochemistry and nutrition from Memorial University of Newfoundland and earned her Doctor of Naturopathic Medicine from Bastyr University. Dr. Stagg is the author of The Bitter Prescription and Unzip Your Genes, and she co-hosts The Natural Doctors. Her work focuses on gut health, the microbiome, precision lifestyle medicine, inflammation, metabolic health, and helping patients address the root causes of chronic disease. 📌 Learn More About Dr. Jennifer Stagg Website: https://www.drstagg.com/ Whole Health Wellness Center: https://www.wholehealthllc.com/providers/dr-jennifer-j-stagg/ YouTube: https://www.youtube.com/@TheNaturalDoctors Facebook: https://www.facebook.com/drjenniferstagg/ The Bitter Prescription: https://www.drstagg.com/the-bitter-prescription/ Unzip Your Genes: https://www.drstagg.com/unzipyourgenes/ 📌 Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK 📌 Featured Event Dr. Jennifer Stagg and Dr. Greg Jones are both featured speakers at the EPIC Functional Medicine Conference 2026, sponsored by Biotics Research. Register here: https://www.bioticsresearch.com/epic2026  🔗 Authoritative Resources & Further Reading • Harvard Health – The Gut-Brain Connection: https://www.health.harvard.edu/diseases-and-conditions/the-gut-brain-connection • NIH/NCCIH – Probiotics: What You Need To Know: https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know 🔬 Timestamps How Dr. Jennifer Stagg found functional medicine (00:00 - 04:41) Why so many health problems start in the gut (04:41 - 07:37) What is the gut-brain axis? (07:37 - 11:46) How the vagus nerve connects your gut and brain (11:46 - 15:24) What dysbiosis really means (15:24 - 19:12) How stress changes your gut (19:12 - 25:12) How to choose the right probiotic (25:12 - 29:12) What causes leaky gut? (29:12 - 31:44) Why butyrate is important for gut health (31:44 - 36:37) Why your gut is called the second brain (36:37 - 42:25) Can probiotics improve mood? (42:25 - 45:51) Simple ways to improve your gut health (45:51 - 51:37) Gut health problems you should not ignore (51:37 - 52:48) Final thoughts on protecting your gut (52:48 - 53:17)

Dr. Jones clarifies how the combination of CJC-1295 and Ipamorelin can enhance growth hormone production and release. He elucidates the science in this peptides explained video, highlighting the potential health benefits his patients have experienced with ipamorelin and peptide therapy. Understand how these growth hormone-stimulating compounds work together.CHAPTERS00:00 What Are CJC-1295 and Ipamorelin?01:00 How They Work Together to Boost Growth Hormone02:00 The Well-Known Benefit: Muscle Growth & Fat Loss03:04 Surprising Benefit #1: Deep Restorative Sleep03:39 Surprising Benefit #2: Sharper Focus & Brain Function04:08 Surprising Benefit #3: Joint, Tendon & Ligament Repair04:37 Surprising Benefit #4: Improved Skin Health & Elasticity05:05 Surprising Benefit #5: Stronger Bones & Osteoporosis Prevention05:46 Final Thoughts & How to Learn MoreConnect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/ 📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@DrJonesNMDTV 🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ ____________________________The information provided in this video is solely for educational and informational purposes. It is not intended to provide medical advice or to diagnose, treat, cure, or manage any health condition. Viewing this content does not establish or imply a doctor–patient relationship. You should not rely on this content as a substitute for consultation with a licensed healthcare professional regarding your own specific medical questions or health concerns. Always seek the advice of your physician or other qualified healthcare provider before starting, stopping, or changing any medication, supplement, treatment, or lifestyle program. Never disregard professional medical advice or delay seeking it because of something you have seen in this video. If you believe you may be experiencing a medical emergency, call 911 or your local emergency number immediately.

Learn how peptides can support muscle growth, recovery, and performance without the risks of anabolic steroids. This video explains sarcopenia, the role of growth hormone–supporting peptides like CJC-1295, Ipamorelin, BPC-157, and PEG-MGF, and how to stack them safely for longevity and lean mass. Discover a smarter, physiology-based approach to building muscle and optimizing healthspan.CHAPTERS00:00 Why Muscle Matters for Longevity00:50 Understanding Sarcopenia and Muscle Loss with Age01:26 Risks of Traditional Steroids and Performance Drugs02:08 The Peptide Strategy for Smarter Muscle Building02:44 Foundational Health Before Using Peptides02:48 Key Peptides for Muscle Growth and Recovery04:27 How to Stack Peptides Based on Your Goals06:04 Cycling, Timing, and Monitoring for SafetyConnect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/ 📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@UCM2Jjqb7MqtZ7VDIuRjguLA 🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ ____________________________The information provided in this video is solely for educational and informational purposes. It is not intended to provide medical advice or to diagnose, treat, cure, or manage any health condition. Viewing this content does not establish or imply a doctor–patient relationship. You should not rely on this content as a substitute for consultation with a licensed healthcare professional regarding your own specific medical questions or health concerns. Always seek the advice of your physician or other qualified healthcare provider before starting, stopping, or changing any medication, supplement, treatment, or lifestyle program. Never disregard professional medical advice or delay seeking it because of something you have seen in this video. If you believe you may be experiencing a medical emergency, call 911 or your local emergency number immediately.

Recurring injuries are often not just about bad luck, poor form, or one wrong movement. In this episode, Dr. Greg Jones sits down with Dr. Stefi Cohen, Doctor of Physical Therapy, strength coach, entrepreneur, and world-record powerlifter, to explain why injuries keep coming back and how training load, tissue capacity, recovery, and pain science all shape long-term healing. They discuss why active people often experience recurring back pain, shoulder injuries, and training setbacks even when they are doing “the right exercises.”  This conversation also covers the role of deadlifts, lifting technique, efficient movement, early injury management, shoulder pain red flags, regenerative medicine, PRP, prolotherapy, peptides, and practical ways to build a stronger, more resilient body.  If you are an athlete, coach, clinician, or active adult trying to recover from injury, train smarter, and prevent setbacks, this episode offers a clear framework for improving performance while respecting recovery. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 📌 About Dr. Stefi CohenDr. Stefi Cohen is a Doctor of Physical Therapy, strength coach, entrepreneur, and 25-time world-record-holding powerlifter. She made history as the first woman to deadlift 4.4 times her body weight in competition and has dedicated her career to helping athletes and active adults train smarter through evidence-based principles. Her work focuses on pain science, injury recovery, strength training, performance, and bridging the gap between rehabilitation and high-level training. Through the Institute of Strength Training, Dr. Cohen educates coaches, clinicians, and athletes on practical strategies for improving movement, managing pain, and building long-term resilience. 📌 Learn More About Dr. Stefi Cohen Website: https://instituteofstrengthtraining.com/ YouTube: https://www.youtube.com/@DrStefiCohen Instagram: https://www.instagram.com/steficohen/ Training Programs: https://www.hybridperformancemethod.com/ 📌 Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK 🔗 Authoritative Resources & Further Reading • MRI findings, disc degeneration, and low back pain https://pubmed.ncbi.nlm.nih.gov/26359154/ • Recent clinical practice guidelines for low back pain managementhttps://pubmed.ncbi.nlm.nih.gov/38693474/ • Training load capacity and injury riskhttps://pubmed.ncbi.nlm.nih.gov/34124660/  🔬 TimestampsIntroduction to Dr. Stefi Cohen (00:00 - 03:04) Combining strength training and physical therapy (03:04 - 04:24) Why injuries happen in active people (04:24 - 05:17) The biggest mistake athletes make when training (05:17 - 08:37) Why pain should not be ignored (08:37 - 10:03) Understanding low back pain and recurring injuries (10:03 - 13:03) When an MRI does not explain your pain (13:03 - 16:16) Should you rely on imaging or function? (16:16 - 18:21) Coaching athletes through pain and injury (18:21 - 19:25) Why deadlifts do not cause injuries (19:25 - 21:15) Is there really a “perfect” lifting technique? (21:15 - 25:44) Efficient movement vs. perfect form (25:44 - 30:55) What to do during the first 72 hours after a back injury (30:55 - 34:35) Why shoulder injuries are so common (34:35 - 37:39) When shoulder pain needs more than exercise (37:39 - 41:36) Recognizing the warning signs of a serious shoulder injury (41:36 - 44:31) Regenerative medicine, PRP, prolotherapy, and peptides (44:31 - 50:20) Building resilience through smarter training (50:20 - 55:42) Key takeaways for preventing recurring injuries (55:42 - 01:00:28) Where to connect with Dr. Stefi Cohen (01:00:28 - 01:01:40)

Semax is a neuroprotective peptide studied for memory, focus, learning, and mental performance without the jitteriness of stimulants. In this video, Dr. Greg Jones explains how Semax increases BDNF, supports neuroplasticity, influences dopamine and serotonin, and why it has been used clinically for brain recovery and cognitive support. He also covers delivery methods, safety considerations, and who may benefit most.CHAPTERS00:00 What Semax Is and Why It’s Different From Stimulants00:31 History of Semax and Clinical Use in Russia01:18 How Semax Increases BDNF and Supports Neuroplasticity02:09 Cognitive, Mood, and Neuroprotective Benefits03:18 Nasal Spray vs Injectable Semax04:18 Safety, Side Effects, and Who Should Be CautiousConnect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/ 📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@DrGregJonesNMD🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ ____________________________The information provided in this video is solely for educational and informational purposes. It is not intended to provide medical advice or to diagnose, treat, cure, or manage any health condition. Viewing this content does not establish or imply a doctor–patient relationship. You should not rely on this content as a substitute for consultation with a licensed healthcare professional regarding your own specific medical questions or health concerns. Always seek the advice of your physician or other qualified healthcare provider before starting, stopping, or changing any medication, supplement, treatment, or lifestyle program. Never disregard professional medical advice or delay seeking it because of something you have seen in this video. If you believe you may be experiencing a medical emergency, call 911 or your local emergency number immediately.

Orforglipron is a new oral GLP-1 medication for weight loss, and many patients are asking how it compares to injectable options like Ozempic, Wegovy, and Zepbound. In this episode, Dr. Greg Jones is joined by Dr. Kris Wusterhausen to explain what orforglipron is, how it works, and where it may fit in the future of medical weight management. They discuss why this oral GLP-1 is different from traditional peptide-based therapies, including how small-molecule medications may affect absorption, dosing convenience, and patient accessibility. The conversation also covers what current research shows about weight-loss results, blood sugar changes, cardiovascular markers, side effects, contraception considerations, surgical precautions, and long-term use. If you are curious about orforglipron, oral GLP-1 medications, weight-loss drugs, metabolic health, muscle preservation, or how these therapies compare with injectable GLP-1 options, this episode offers a practical, clinically informed overview of the benefits, limitations, and unanswered questions. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 📌 About Dr. Kris Wusterhausen Dr. Kris Wusterhausen, DO, is a board-certified Family Medicine physician and founder of The Resurge Clinic in Weatherford, Texas. For nearly two decades, he has focused on hormone optimization, metabolic health, weight management, peptide therapy, and longevity medicine. In addition to caring for patients, Dr. Wusterhausen serves as Medical Director of the BioTE Training Clinic, where he helps educate healthcare providers on advanced approaches to preventive and age-management medicine. He is also a nationally recognized speaker who regularly lectures on hormones, peptides, body composition, and long-term health optimization. 📌Learn More About Dr. Kris Wusterhausen Website: https://www.theresurgeclinic.com/ About Dr. Kris: https://www.theresurgeclinic.com/about/ Facebook: https://www.facebook.com/theresurgeclinic/ YouTube: https://www.youtube.com/playlist?list=PLPZhIf03cd8xu7_CKwAc41vdpeUEQMtem 📌Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK 🔗 Want to learn more? Check these resources: • FDA Prescribing Information – Foundayo/orforglipron: https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/220934Orig1s000lbl.pdf  • Lilly – Foundayo/orforglipron FDA Approval Announcement: https://investor.lilly.com/news-releases/news-release-details/fda-approves-lillys-foundayotm-orforglipron-only-glp-1-pill  • Daily oral orforglipron for adults with obesityhttps://pubmed.ncbi.nlm.nih.gov/37351564/  • Oral orforglipron for type 2 diabetes, HbA1c, and body weighthttps://pubmed.ncbi.nlm.nih.gov/37369232/  🔬 Timestamps Introduction and recap of previous episodes (00:00 - 04:27) The evolution of longevity medicine (04:27 - 06:39) Understanding orforglipron as a new molecule (06:39 - 08:08) Bioavailability and absorption: small molecules vs. peptides (08:08 - 13:21) Clinical implications of orforglipron (13:21 - 16:48) Weight loss and patient expectations (16:48 - 20:45) Secondary benefits and cardiovascular health (20:45 - 24:49) Contraception considerations with orforglipron (24:49 - 29:17) Understanding GLP-1 and its implications (29:17 - 30:14) Surgical considerations with GLP-1 medications (30:14 - 33:39) Muscle preservation and management on GLP-1s (33:39 - 40:33) Integrating GLP-1s into hormone optimization protocols (40:33 - 45:30) Cost and accessibility of GLP-1 medications (45:30 - 49:53) Conclusions and future directions for GLP-1s (49:53 - 56:10)

AI in medicine is rapidly changing how doctors analyze symptoms, review lab results, evaluate research, and make clinical decisions. In this episode, Dr. Greg Jones sits down with Dr. Jeffrey Wiegers, a board-certified anesthesiologist and interventional pain specialist at BioReset Medical, to discuss how artificial intelligence and machine learning are reshaping the future of healthcare. They explore why doctors should view AI as a clinical assistant rather than a replacement, and how emerging tools may help improve diagnostic support, patient education, research discovery, clinical workflows, and personalized medicine. The conversation also addresses the risks of AI in healthcare, including overreliance, bias, incomplete context, accountability, and the importance of keeping trained clinicians at the center of medical decision-making. If you are interested in artificial intelligence in medicine, machine learning in healthcare, personalized medicine, regenerative medicine, or the future of doctor-patient care, this episode offers a practical look at both the promise and limitations of AI.Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/📌 About Dr. Jeffrey WiegersDr. Jeffrey Wiegers, MD, is a board-certified anesthesiologist and interventional pain specialist with fellowship training from Cedars-Sinai. He is a physician at BioReset Medical, where he focuses on regenerative medicine, longevity, sports medicine, and complex chronic conditions.Dr. Wiegers is also involved in education and emerging healthcare technologies, with a particular interest in how innovation, regenerative medicine, and AI may improve patient outcomes.📌 Learn More About Dr. Jeffrey Wiegers Website: https://www.bioresetmedical.com/ Dr. Wiegers Bio: https://www.bioresetmedical.com/dr-jeffrey-wiegers LinkedIn: https://www.linkedin.com/in/jeffrey-wiegers-m-d-9bb65690 Instagram: https://www.instagram.com/jeffwiegers/📌 Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK🔗 Want to learn more? Check these resources:American Medical Association – Augmented Intelligence in Medicine: https://www.ama-assn.org/practice-management/digital-health/augmented-intelligence-medicine FDA – Artificial Intelligence in Drug and Biological Product Decision-Making: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/considerations-use-artificial-intelligence-support-regulatory-decision-making-drug-and-biological Ethical Considerations in AI and Machine Learning in Healthcarehttps://pubmed.ncbi.nlm.nih.gov/39011215/ 🔬 TimestampsIntroduction and background of Dr. Jeff Wiegers (00:00 - 04:46)The role of AI in medicine (04:46 - 09:31)AI’s impact on medical specialties (09:31 - 14:16)Patient empowerment through AI (14:16 - 21:12)The future of AI in healthcare (21:12 - 25:01)AI in clinical practice: opportunities and challenges (25:01 - 31:52)Concerns and risks of AI in diagnostics (31:52 - 32:41)Trust and credibility in AI and healthcare (32:41 - 33:39)The role of clinicians in AI integration (33:39 - 34:49)AI’s impact on diagnostic skills (34:49 - 35:16)The limitations of AI in treatment plans (35:16 - 36:23)Accountability in AI-driven healthcare (36:23 - 38:20)Mental health and AI: a cautionary tale (38:20 - 39:32)AI tools for clinicians (39:32 - 40:44)The future of clinical trials with AI (40:44 - 46:23)Peptides and AI: a new frontier (46:23 - 49:05)The promise of personalized medicine (49:05 - 51:43)Advice for engaging with AI in healthcare (51:43 - 54:58)Conclusion and final thoughts (54:58 - 58:52)

Gut health plays a major role in chronic disease, inflammation, metabolism, and healthy aging. In this episode, Dr. Greg Jones explores how the gut microbiome influences whole-body health, why SIBO can cause widespread dysfunction, and how modern lifestyles may contribute to metabolic decline and muscle loss. The episode covers the risks of rapid weight loss from low-calorie dieting and GLP-1 medications, including potential lean mass loss, sarcopenia, myosteatosis, and long-term metabolic slowdown. If you are interested in gut health, SIBO, microbiome repair, muscle preservation, healthy aging, or metabolic optimization, this episode offers practical insight into rebuilding health from the inside out. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 📌 About Dr. William Davis Dr. William Davis is a preventive cardiologist, #1 New York Times bestselling author, and leading voice in microbiome and metabolic health. He is best known for the global Wheat Belly movement, which challenged conventional nutrition advice and highlighted the inflammatory and metabolic impact of modern wheat and ultra-processed foods. Through books including Wheat Belly, Undoctored, Super Gut, and SUPER Body, Dr. Davis has helped shift the conversation from symptom management to root-cause health restoration. His latest work focuses on body composition, muscle preservation, gut microbiome repair, and practical strategies to support long-term vitality, strength, and metabolic resilience. 🔗 Learn More About Dr. William Davis Website: https://drdavisinfinitehealth.com/ Blog: https://www.williamdavismd.com/ YouTube: https://www.youtube.com/@WilliamDavisMD Instagram: https://www.instagram.com/drdavisinfinitehealth/ Facebook: https://www.facebook.com/DrDavisInfiniteHealth/Book: https://www.hachettebookgroup.com/titles/william-davis-md/super-body/9780306835995/ 🔗 Connect with Dr. Greg Jones Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/ Enovative Wellness Center: https://enovativewellness.com/ Instagram: https://www.instagram.com/doctorjones_doctorjones/ Facebook: https://www.facebook.com/GregJonesNMD YouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK 🔗 Authoritative Resources & Further Reading • Mayo Clinic – SIBO Diagnosis & Treatment: https://www.mayoclinic.org/diseases-conditions/small-intestinal-bacterial-overgrowth/diagnosis-treatment/drc-20370172 • NIDDK – Gastrointestinal Microbiology & Infectious Diseases: https://www.niddk.nih.gov/research-funding/research-programs/gastrointestinal-microbiology-infectious-diseases 🔬 Timestamps Why a cardiologist started talking about gut health (00:00 - 05:19) How the microbiome connects to chronic disease (05:19 - 06:24) Antibiotics, pregnancy, and missing microbes (06:24 - 11:39) Why cholesterol guidelines still miss the bigger picture (11:39 - 19:42) The loss of healthy gut microbes in modern humans (19:42 - 23:36) What SIBO is and why it impacts the entire body (23:36 - 29:31) Breath testing, hydrogen gas, and detecting SIBO (29:31 - 43:18) Why low-FODMAP diets do not solve the root problem (43:18 - 45:14) Lactobacillus reuteri and the oxytocin connection (45:14 - 49:18) The problem with rapid weight loss and GLP-1s (49:18 - 52:49) Why losing muscle accelerates aging (52:49 - 57:07) Myosteatosis: fat deposits inside muscle tissue (57:07 - 59:45) The gut-muscle axis and preserving strength (59:45 - 01:02:00) Affordable ways to track muscle and visceral fat (01:02:00 - 01:05:44) First steps to rebuilding metabolic health (01:05:44 - 01:08:59) Where to learn more (01:08:59 - 01:11:26)

In this video, I explain what AMPK is and its central role in metabolism and aging. Discover how AMPK activation can lead to significant fat loss and improved metabolic function. We also explore the extensive AMPK benefits, including enhanced cellular respiration and reduced oxidative stress, offering valuable longevity tips.CHAPTERS00:00 Why ATX-304 Matters for Energy & Longevity00:48 What AMPK Is and Why It Controls Metabolism01:48 What ATX-304 Actually Does02:58 The Potential Health Benefits04:24 ATX-304 vs PQQ and CoQ1005:18 Safety, Dosing, and What We Don’t Know06:13 Final Thoughts on ATX-304Connect with Dr. Greg Jones Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/Instagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/ 📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@DrGregJonesNMD🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ ____________________________The information provided in this video is solely for educational and informational purposes. It is not intended to provide medical advice or to diagnose, treat, cure, or manage any health condition. Viewing this content does not establish or imply a doctor–patient relationship. You should not rely on this content as a substitute for consultation with a licensed healthcare professional regarding your own specific medical questions or health concerns. Always seek the advice of your physician or other qualified healthcare provider before starting, stopping, or changing any medication, supplement, treatment, or lifestyle program. Never disregard professional medical advice or delay seeking it because of something you have seen in this video. If you believe you may be experiencing a medical emergency, call 911 or your local emergency number immediately.

Hormone optimization goes beyond testosterone and estrogen. In this episode of the Optimization Academy Podcast, Dr. Greg Jones talks with Ashley Madsen, PA-C, about why symptoms like fatigue, brain fog, low libido, weight changes, poor recovery, and perimenopause concerns often need a deeper, more personalized approach. They discuss why testosterone levels are dropping in younger men, why many women’s hormone symptoms are dismissed or misunderstood, and how stress, sleep, toxins, lifestyle, body composition, and metabolic health can affect hormone balance. Ashley also breaks down common misconceptions around testosterone therapy, estrogen, progesterone, peptide therapy, genomics, and longevity medicine. If you’ve been searching for answers around low testosterone, perimenopause, fatigue, brain fog, weight resistance, hormone therapy, or recovery, this episode offers a practical look at what may actually be driving those changes, and why symptoms, labs, lifestyle, and personalized care all matter. 📌 About Ashley Madsen, PA-CAshley Madsen, PA-C, is a board-certified physician assistant specializing in hormone optimization, longevity medicine, peptide therapy, genomics, and performance health. She has advanced training through Stanford University, the Institute for Functional Medicine, and the American Board of Anti-Aging Medicine. She is also the co-founder of Lamarra Collective. Get 10% off your first order at Dr. Jones Supplement Store when you join the email list. https://drjonessupplements.com/ 🔗 Learn more about Ashley Madsen, PA-C Website: https://ashleymadsen.com, https://lumara-collective.com LinkedIn: https://www.linkedin.com/in/ashleymadsen-lumara Instagram: https://www.instagram.com/ashleymadsenofficial/ 📌 Connect with Dr. Greg JonesInstagram: @doctorjones_doctorjonesFacebook: https://www.facebook.com/gregjonesnmd Enovative Wellness Center: https://enovativewellness.com/ Book Dr. Jones to speak at your next event: https://www.drjonesnmd.com/  📣 Subscribe + FollowYouTube: https://www.youtube.com/@DrGregJonesNMD Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK  🔬 TimestampsWhy Hormone Health Is So Confusing Today (00:00 - 07:23) Stress, Toxins & Lifestyle Factors Affecting Hormones (07:23 - 13:57) Estrogen, Progesterone & Hormone Myths (13:57 - 18:59) Symptoms Many Women Get Told to Ignore (18:59 - 25:22) What Women Experience During Perimenopause (25:22 - 32:23) Common Myths About Testosterone Therapy (32:23 - 36:42) Testosterone Levels Are Dropping in Younger Men (36:42 - 38:37) Sleep, Recovery & Metabolic Health (38:37 - 42:29) Why Body Composition Matters More Than Weight (42:29 - 48:42) Genomics & Personalized Longevity Medicine (48:42 - 51:34) Peptide Therapy Explained Simply (51:34 - 01:12:11) The Future of Hormone Optimization (01:12:11 - 01:17:52) 🔍 Want to Learn More? Here is the science discussed in today's episode: PMID: 17062768 Testosterone concentrations in young adult men have declined over time PMID: 37326322 Menopause hormone therapy and women’s health research PMID: 31474158 Environmental and lifestyle factors linked to testosterone decline PMID: 31599840 Testosterone deficiency and metabolic health PMID: 36735255 Hormone optimization and longevity medicine research

In this episode, Dr. Jones provides valuable clinical insights into methylene blue, a compelling tool for biohacking. He explains how it addresses mitochondrial dysfunction and supports overall mitochondrial health, which is essential to boost energy levels and improve brain function. CHAPTERS00:00 What Methylene Blue Is and Why It’s Trending00:29 How Methylene Blue Works in the Body01:49 Mitochondrial Energy and Fatigue Support02:22 Cognitive, Memory, and Brain Health Benefits03:04 Why Product Quality and Source MatterConnect with Dr. Greg JonesInstagram: @doctorjones_doctorjones 📺 YouTube: https://www.youtube.com/@DrGregJonesNMD____________________________The information provided in this video is solely for educational and informational purposes. It is not intended to provide medical advice or to diagnose, treat, cure, or manage any health condition. Viewing this content does not establish or imply a doctor–patient relationship. You should not rely on this content as a substitute for consultation with a licensed healthcare professional regarding your own specific medical questions or health concerns. Always seek the advice of your physician or other qualified healthcare provider before starting, stopping, or changing any medication, supplement, treatment, or lifestyle program. Never disregard professional medical advice or delay seeking it because of something you have seen in this video. If you believe you may be experiencing a medical emergency, call 911 or your local emergency number immediately.