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In this episode, UROONCO BCa chief editor Dr. Benjamin Pradere interviews Assoc. Prof. Yige Bao about his ESMO26 presentation of the Phase II WUTSUP-02 trial results. The WUTSUP-02 trial (ChiCTR2300067836) is a prospective, multi-centre, phase II study evaluating perioperative tislelizumab plus disitamab vedotin for upper tract urothelial carcinoma (UTUC).  They discuss the study design, patient population, and key trial endpoints, before reviewing the efficacy, survival, and safety results, including treatment-related adverse events. Their conversation also examines the clinical significance of these findings, their potential impact on the treatment landscape for UTUC, and the next steps needed to further evaluate HER2-targeted therapies and move toward broader clinical implementation. For more details on this study, you can read the abstract on the UROONCO BCa Educational Platform. This interview was recorded at ESMO26. For more updates on bladder cancer, please visit our educational platform UROONCO BCa. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO BCa chief editor Dr. Benjamin Pradere interviews Assoc. Prof. Andrea Necchi about the results from the phase 3 CA017-078 (ENERGIZE) trial, which he presented at ESMO26. The trial investigates neoadjuvant chemotherapy alone versus in combination with nivolumab, followed by postsurgical adjuvant nivolumab, in patients with muscle-invasive bladder cancer (MIBC).  Assoc. Prof. Andrea Necchi discusses the rationale and design of the trial, as well as the implications of its negative results, with neither co-primary endpoint, pathological complete response (pCR) and event-free survival (EFS) being met. They also talk about the potential role of circulating tumour DNA (ctDNA) in treatment monitoring, risk stratification, and future clinical trial design. For more details on this study, you can read the abstract on the UROONCO BCa Educational Platform. This interview was recorded at ESMO26. For more updates on bladder cancer, please visit our educational platform UROONCO BCa. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

How can urology become more sustainable, and what practical steps can healthcare professionals take to reduce their environmental impact? In this episode, Dr. Benjamin Pradère (FR) Chair of the Go Green Working Group is joined by Dr. Sanne Jansen (NL) and Dr. Horst Emanuel Lagos-Beitz (MX) to introduce this new EAU Working Group endorsed by the YUO and discuss sustainability initiatives in urological practice. Their conversation explores practical projects from the Netherlands and Mexico, including reducing plastic waste, recycling medical materials and improving sustainability in the operating room. The faculty also discuss the challenges of implementing greener practices, the importance of education and collaboration, and how small changes can contribute to more sustainable urological care. This podcast is brought to you in collaboration with the EAU Go Green Working Group. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

UROONCO PCa associate editor Assoc. Prof. Pawel Rajwa speaks with Assoc. Prof. Arvin George from Johns Hopkins University (US) about the current state and future direction of focal therapy for prostate cancer. They discuss a wide range of topics, including the ideal candidates for focal therapy, how treatment success should be defined, and which technologies currently offer the greatest potential. The conversation also explores practical aspects of clinical care, such as how to communicate the potential benefits and limitations of focal therapy to patients, what could further improve treatment outcomes, and what advice can be offered to urologists looking to enter the field and begin offering focal therapy to their patients. For more updates on prostate cancer, please visit our educational platform UROONCO PCa. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

What does it take to move from Latin America to the UK and build a career in a new healthcare system? In this second episode of the Beyond borders: Latin American voices in European urology series, Dr. Alejandra Bravo-Balado (ES) is joined by Dr. Florencia Frascheri (GB), a urologist from Argentina currently working in the UK. They discuss her journey from Argentina to the UK, including the practical steps involved in pursuing a fellowship, adapting to a different healthcare system and working in a new language. The conversation also explores the importance of mentorship, opportunities for research and professional development, and the work–life balance she has found in the UK. Dr. Frascheri also reflects on the personal side of building a life away from home and shares practical advice for young urologists considering a similar path. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

What does it take to leave an established career behind and build a new professional life as a urologist in Europe? In this first episode of the Beyond borders: Latin American voices in European urology series, Dr. Alejandra Bravo-Balado (ES) is joined by Dr. Mariela Corrales Acosta (FR), a urologist from Peru currently working in France. They discuss her journey from Latin America to Europe, including the challenges of validating her qualifications, adapting to a new healthcare system and culture, and establishing herself professionally abroad. The conversation also explores the importance of mentorship and resilience, differences in work–life balance, and the personal sacrifices that come with international mobility. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO PCa associate editor Prof. Claudia Kesch interviews Dr. Neeraj Agarwal, from Dana-Farber Cancer Institute on the recent results of the TALAPRO-3 trial. This trial investigates the efficacy and safety of TALA + ENZA in men with mCSPC bearing HRR gene alterations. Dr. Agarwal elaborates on the rationale of this trial and the key results. They also discuss the control arm in more detail, heterogeneity and HRR alteration, plus clinical practice of managing anaemia and treatment strategy in mHSPC.  To know more on this trial, read the abstract.  For more updates on prostate cancer, please visit our educational platform UROONCO PCa. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

How can small renal masses be managed beyond surgery, and how should the most appropriate approach be selected for each patient? In this episode, Prof. Daniela Oprea-Lager (NL) is joined by Assoc. Prof. Lorenzo Bianchi (IT) and Dr. Giuseppe Basile (GB) to discuss the evolving management of small renal masses. The faculty explore patient selection for active surveillance and ablative treatments, the role and timing of renal mass biopsy, and imaging strategies for solid and cystic renal masses. The discussion also looks towards the future, including molecular imaging, biomarkers, liquid biopsy and artificial intelligence, and considers how these developments may improve tumour characterisation, treatment selection and follow-up while supporting a more individualised approach to patient care. This podcast is brought to you in collaboration with the EAU Section of Urological Imaging. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In “Membranous urethral length and post-prostatectomy stress urinary incontinence”, Dr. Béatrice Bouchard (CA) examines membranous urethral length (MUL) as a predictor of continence outcomes after prostatectomy. Based on a retrospective study of 161 men, she shows that patients with post-prostatectomy incontinence have a substantially shorter MUL compared with men presenting urgency incontinence, findings consistent with MRI data.  The episode outlines how urethral pressure profiling, performed during routine urodynamics using the Brown and Wickham technique, can reliably measure MUL and provide clinically useful information. Dr. Bouchard highlights the method’s potential value for risk stratification, patient counselling, and guiding surgical strategies aimed at preserving urethral length and improving functional outcomes.  For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

How can general urologists recognise when lower urinary tract symptoms may have a neurological cause, and what are the key signs that should prompt further investigation? In this episode, Prof. Sanjay Sinha is joined by Dr. Charalampos Konstantinidis, Dr. Stefania Musco and Prof. Marcio Averbeck to discuss a practical approach to suspecting neurogenic lower urinary tract symptoms in everyday clinical practice. The conversation explores the clinical features that should raise suspicion of an underlying neurological disorder, the importance of a comprehensive history, physical examination and simple diagnostic tests, and how to distinguish neurogenic LUTS from more common urological conditions. The faculty also discuss common clinical scenarios, highlight when further neurological assessment or urodynamic evaluation may be appropriate, and share practical advice to help general urologists avoid missed diagnoses. This podcast is brought to you in collaboration with the EAU Section of Functional Urology. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

This EAUN edition presents the episode “No Place to Go: Homelessness & Incontinence.” Eva Wallace, Clinical Nurse Advisor and Chair of the EAUN Special Interest Group (SIG) Continence, is joined by Anne Marie Kelly, Clinical Nurse Specialist in Continence with the Health Service Executive (HSE) in the Dublin area, for an important conversation on the often-overlooked connection between homelessness and incontinence. Without reliable access to toilets, hygiene facilities, clean clothing or continence products, a manageable condition can become a daily struggle, affecting dignity, health and social inclusion. The discussion explores the practical challenges faced by people experiencing homelessness and highlights how incontinence can further complicate an already vulnerable situation. By bringing this hidden issue into the open, the episode considers how compassionate, practical continence care can make a meaningful difference for people without a place to call home. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

How should short bulbar urethral strictures be assessed and treated and which factors should guide the choice between the available techniques? In this episode, Dr. Marjan Waterloos is joined by Dr. Saskia Morgenstern, Dr. Felix Campos Juanatey and Dr. Leonidas Karapanos to discuss the management of short bulbar urethral strictures and the different treatment options available in clinical practice. The conversation explores the diagnostic work-up of urethral strictures, including the role of urethrography, urethroscopy and patient-reported outcome measures, before discussing the indications for endoscopic treatment and urethroplasty. The faculty compare different surgical approaches, consider how stricture characteristics and patient preferences influence treatment selection, and discuss how outcomes should be evaluated during follow-up. The episode also highlights the importance of looking beyond anatomical success by considering functional outcomes, patient satisfaction and quality of life. This podcast is brought to you in collaboration with the EAU Section of Genitourinary Reconstructive Surgeons.  Their annual meeting takes place in Ghent, (BE) on 24-25 September, where you can expect more on this topic. See details on their website if you would like to join - https://esgurs.uroweb.org/ For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Editor at the EAU Central Office and historian Mr. Loek Keizer speaks to urologist Prof. Javier Angulo Cuesta, one of the foremost authorities on Joaquín Albarrán (1860-1912) about Albarrán’s storied life and ongoing research into this very interesting period in early urology. After a brief overview of Albarrán’s remarkable and legendary career, which took him from Cuba to Paris via Spain, Prof. Cuesta shares some new insights that recently came to light. Recently unearthed poems by Albarrán’s hand give a more complete picture of the famous urologist, as an orphaned son, and a man who moved in political and artistic expat circles in Europe. The episode offers a fascinating look at the physician, scientist and man behind one of the most influential names in the history of urology. You can find out more about the life and times of Joaquín Albarrán in the EAU’s online European Museum of Urology.The 270-page book Joaquín Albarrán: The Life and Scientific Passion of a Medical Genius by Dr. Marlene Fernández Arias, published by the EAU History Office in 2014 is available for sale in the EAU’s online shop.Website of the Spanish Association of Urology’s History Office with their Spanish-language publications.This podcast is brought to you in collaboration with the EAU History Office. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO PCa associate editor Dr. Jennifer Le Guévelou speaks with radiation oncologist Prof. Pierre Blanchard on the results of the PEACE 2 phase III randomised trial investigating prophylactic pelvic radiotherapy (RT) targeting pelvic nodal micrometastases and/or cabazitaxel may both reduce the risk of relapse and improve outcomes in patients with very high-risk localised prostate cancer. They discuss the design of the PEACE 2 trial, and its key findings, which showed that whole-pelvic radiotherapy yielded only a minimal trend towards improving clinical progression-free survival, with no significant impact on secondary endpoints, including metastasis-free survival and overall survival.  For more updates on prostate cancer, please visit our educational platform UROONCO PCa. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO PCa chief editor Dr. Giancarlo Marra interviews Prof. Mary-Ellen Taplin from Dana–Farber Cancer Institute in the United States, on the results of the PROTEUS trial.  The PROTEUS trial is a phase 3, double-blind, placebo-controlled trial evaluating the benefit of adding apalutamide to standard androgen deprivation therapy (ADT) in men with high-risk, localised prostate cancer undergoing radical prostatectomy. They discuss the rationale, patient selection and the results of this trial (dual primary endpoint), as well as the impact of the results on clinical practice. Prof. Taplin concludes in the take-home messages that this trial has illustrated the progress being made in regard to preventing and delaying relapse. To know more on this trial, read the abstract with expert commentary by UROONCO PCa associate editor Assoc. Prof. Pawel Rajwa.  For more updates on prostate cancer, please visit our educational platform UROONCO PCa. For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.