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Most detoxes leave you feeling worse. Here's the gentler approach a formulator actually uses. Naturopathic physician Dr. Greg Kelly returns to the show to answer a simple question: if your liver and kidneys already detox you, why would you ever need help? He explains why modern exposure outpaces those organs, why losing weight can recirculate stored toxins, and how to support detox without the rough healing crisis many cleanses cause. Meet our guest Dr. Greg Kelly is Director of Product Development at Neurohacker Collective (Qualia), a naturopathic physician (N.D.), and author of the book Shape Shift. He was the editor of the journal Alternative Medicine Review, taught Advanced Clinical Nutrition at the University of Bridgeport College of Naturopathic Medicine, and has more than 30 journal articles indexed on PubMed. He leads the team that formulated the Qualia 2-Day Detox. Resources & tools: Create your FREE Outliyr account and unlock special tools and resources: https://get.outliyr.com Qualia 2-Day Detox, Qualia Senolytic & Qualia Mind (code URBAN saves 15% on any Qualia product): https://outliyr.com/go/qualia  Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways People are exposed to more than 350,000 chemicals, and about a third are proprietary formulas no one can identify. In one weight-loss study, every participant carried at least 19 fat-soluble chemicals, and losing weight pushed them into the blood. Without a binder, those chemicals ended up more concentrated in fat tissue than before. Reducing exposure is always step one: skip anything with a strong chemical smell that isn't a flower. Low-temperature sauna, around 140°F, held longer, favors fat-stored compounds over just water and electrolytes. The brain's glymphatic system does most of its cleaning in deep sleep. Short, full-strength pulses work better than small daily doses your body adapts to. Episode highlights 0:00 Why is there a whole aisle of detox products? 1:25 Why your liver and kidneys can't keep up 5:36 The Last Straw: how toxic load builds up 14:42 Why weight loss can recirculate toxins 23:15 Low-temp vs. high-temp sauna for detox 32:02 Why pulse supplements instead of daily dosing 39:02 The 4-step protocol and glymphatic sleep Links Watch it on YouTube: https://youtu.be/_LjV9DU3cJo  Full episode show notes: https://outliyr.com/285 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if the people you love most are quietly tanking your recovery? Sports scientist Don Moxley returns to the show to break down the difference between sleeping and recovering. He explains what heart rate variability actually measures, why his Ohio State wrestlers posted their worst HRV of the season after a holiday at home, and the simple habits that move your HRV more than anything you can buy. Meet our guest Don Moxley draws on his career as an athlete, sports scientist, and instructor to lead and educate on the science of performance and longevity. He has helped athletes achieve Olympic medals, World and National Championships, and 23 All-Americans. He is the author of The HRV Book and the founder of Mode Method, maker of HRV+. Resources & tools: Create your FREE Outliyr account and unlock special tools and resources: https://get.outliyr.com Energy Leak (find what's draining you and blocking recovery): https://outliyr.com/apps/energy-leak/  Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Waking to an alarm in the middle of a sleep cycle cost Don about 20 points of HRV. Olympians he has worked with carry nighttime HRV above 150 milliseconds. Family stress gave an elite wrestling team its worst HRV readings of the whole season. The vagus nerve spends about 80% of its time reading signals from the body, so what you do with your body shifts your stress state. Overnight HRV is a cleaner reading than a morning check, which is skewed by your waking cortisol rise. Breathing 5 seconds in and 5 seconds out was part of every warm-up for his wrestlers. Sleep comes first among his 7 levers for raising HRV, followed by your breath.   Episode highlights 0:00 Sleeping vs. recovering 9:33 The 5 rocks that build resilience 17:59 Why people give up on their wearables 31:35 The best time to measure HRV 34:07 Why a wrestling team's HRV crashed after the holidays 48:07 The 7 levers: sleep, breathing & vagus nerve stimulation 1:02:34 The coach whose HRV spiked when he prayed Links Watch it on YouTube: https://youtu.be/iqDSK4ArBFw  Full episode show notes: https://outliyr.com/284 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if the blood in your sink is one of the first signs of insulin resistance? In this episode, Dr. James Goolnik, founder of Optimal Dental Health in London and former head of the British Academy of Cosmetic Dentistry, explains what your mouth is telling you about your whole body. He shares why he has zero tolerance for bleeding gums, how gum disease and blood sugar feed each other, and the simple, mostly free habits that rebalance your oral microbiome fast. Meet our guest Dr. James Goolnik is a London-based dentist, nutritionist, and #1 Amazon bestselling author of Kick Sugar. With more than 30 years in practice, he founded Optimal Dental Health in Marylebone, where every new patient sees their own mouth bacteria live under a microscope. He takes a prevention-first approach that connects dentistry with nutrition, sleep, airway health, and the oral microbiome. Resources & tools: Create your FREE Outliyr account and unlock special tools and resources: https://get.outliyr.com Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Treating gum disease can lower HbA1c in people with diabetes, because bleeding gums let mouth bacteria into the bloodstream. Gum disease has 57 known links to other conditions, all running through chronic inflammation. Enamel starts dissolving below a pH of 5.5, so constant snacking keeps your teeth under attack. Brushing removes about 70% of plaque; floss or a water flosser handles the last 30%. Three scrapes a day with a spoon or copper tongue scraper support nitric oxide and blood pressure. Waking up tired, groggy, or with a dry mouth usually means you breathe through your mouth at night. The oral microbiome can be rebalanced within about a week.   Episode highlights 0:00 What your mouth is telling you 2:03 Good, better & best dental care 11:36 Tongue scraping & nitric oxide 14:43 Mouth taping for better sleep & breath 18:18 Why mouthwash is a no-no 31:42 Bleeding gums, blood sugar & 57 disease links 45:25 The one-tooth flossing habit Links Watch it on YouTube: https://youtu.be/NsXI3P_YObY  Full episode show notes: https://outliyr.com/283 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

4 years younger in 6 months. That's what 7 out of 10 people got from a handful of basic minerals and vitamins. Dr. Carolyn Dean, a medical doctor and naturopath and the founder of RnA ReSet, has spent 50 years arguing that most health problems start with missing basics. She shares what her Maui longevity pilot found, why your blood test misses low magnesium, why the vitamin C RDA is far too low, and why small, well-absorbed doses beat megadoses.. Meet our guest Dr. Carolyn Dean is a medical doctor and naturopath who began practicing in 1979. She is the author of more than 35 books, including the bestseller The Magnesium Miracle, Magnesium: The Missing Link to Total Health, and Death by Modern Medicine. Her own severe magnesium deficiency led her to a chemist who could stabilize mineral ions, and in 2015 she launched RnA ReSet. Today she runs a 76-acre certified organic farm with two farm stores in Maui and hosts a weekly podcast that critiques new nutrition research. Resources & tools: Supplement Finder (find supplements that fit your goals and current stack) https://outliyr.com/apps/supplement-finder/  Biological Age Calculator (see how your daily habits affect your pace of aging): https://outliyr.com/biological-age-calculator  Create your FREE Outliyr account and unlock special tools and resources: https://get.outliyr.com Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways 7 of 10 people on her mineral and vitamin formulas slowed their biological aging by an average of 4 years in 6 months. Major stress can cancel out the benefit, even with good nutrition. Only about 1% of your magnesium is in your blood, so doctors dropped it from the standard electrolyte panel. She lists 68 conditions that can be magnesium deficiency misdiagnosed as disease. A brain cell can hold up to 2 million mitochondria, versus about 5,000 in a heart cell, and all of them run on magnesium. About 100 vitamin companies have been bought by Nestlé, Clorox, and drug companies. Start with a quarter teaspoon of colorful sea salt in each liter of filtered water, then add magnesium slowly. Episode highlights 0:00 The fix one layer deeper 11:41 Low-dose beats mega-dose 13:59 Magnesium powers your brain 17:45 The Maui longevity study 27:32 The 10,000 mg vitamin C gap 38:17 Not on your blood test 57:31 Where to start: salt water + magnesium Links Watch it on YouTube: https://youtu.be/bm5Mqtvv5Dw  Full episode show notes: https://outliyr.com/282 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if the knee your doctor wants to replace could be repaired instead? In a 15-year study, 82% of arthritic knees treated with the patient's own bone marrow never needed a knee replacement. Orthopedic surgeon Dr. Marc Pietropaoli stopped doing knee replacements in 2020, and he explains why most knee arthritis pain comes from the bone under the cartilage and what actually repairs it. Meet our guest Dr. Marc Pietropaoli is a sports medicine fellowship-trained orthopedic surgeon who trained under Dr. James Andrews and specializes in regenerative medicine. He founded Victory In Motion, home of Knee Repair, NOT Knee Replacement, and wrote the #1 Amazon best seller Repair NOT Replace. He was the first surgeon in the world to perform an FDA-approved BEAR ACL repair outside of clinical trials. Today his team combines bone marrow concentrate, properly dosed PRP, laser therapy, and whole-body rehab, with the goal of ending the need for knee replacements by 2043. Resources and Tools Light Therapy Dose Calculator: https://outliyr.com/app/light-dose-calculator Create your free Outliyr account: https://get.outliyr.com Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Cartilage has no nerves, so most arthritis pain comes from stress fractures in the bone under it. A bone marrow lesion in one bone around the knee makes a replacement 9 times more likely, and 13 times more likely in more than one spot. 82% of knees treated with bone marrow concentrate avoided replacement over about 15 years. Many "stem cell" shots contain no live cells, and many PRP treatments are underdosed. Cortisone knee injections are linked to needing a replacement sooner. Studies suggest 25% to 30% of joint replacements are unnecessary. ACL prevention training can cut the risk of an ACL tear by 50% to 75%. Episode highlights 0:00 Why we still fix knees with 1960s technology 1:40 The operating room question that started it all 14:23 Why knee pain starts in the bone 16:10 The 15-year study: 82% of knees avoided replacement 21:26 Why some stem cell & PRP treatments fail (dose matters) 34:11 Told you're bone on bone? Ask to see your X-rays 39:41 Preventing knee damage: ACL injuries & BEAR surgery Links Watch it on YouTube: https://youtu.be/ehAmqJS0aoE  Full episode show notes: https://outliyr.com/281 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if you could switch between deep focus and true recovery on command, instead of white-knuckling one gear until you burn out? Serial entrepreneur and Organic Technology creator Hess Adnani joins Nick to map the human operating system: a two-axis model of your nervous system and your mind that tells you where you are and how to move. He explains why recovery is a productivity multiplier, not lost time, and how to read your body's free daily signals instead of leaning only on wearables and bloodwork. Meet our guest Hess Adnani is a serial entrepreneur and innovation ecosystem architect, and the creator of Organic Technology. He built Cyprus's largest startup community, facilitated over two million euros in funding, and helped create 100+ jobs. He now teaches founders to build strong companies and strong inner systems at the same time. Resources & tools: BioEnergetic Baseline (map your energy and nervous-system state): https://outliyr.com/app/bioenergetic-baseline Energy Leak (find what's draining you and blocking recovery): https://outliyr.com/apps/energy-leak/ Braverman Brain-Type Test (understand your default mind state): https://outliyr.com/app/braverman-test-online Create your FREE Outliyr account and unlock special tools and resources: https://get.outliyr.com Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Your internal state sits on two dials: the nervous system and the mind, forming four states of being. Wise mode is open and creative; doer mode is focused and executing. Camping in one mode backfires: doer mode leads to burnout, wise mode to stalling. Hustle past two weeks and output slides toward 50%; two to three days of recovery restores 80% to 90%. Short activations shift your state in minutes, with no equipment. Roughly 20% of your body's daily signals reveal about 80% of your health. Episode highlights 1:47 What Organic Technology is 5:15 Wise mode vs doer mode 19:09 Why camping in one mode burns you out 24:44 Recovery has a quality 37:18 The "invisible jacket" activation 49:30 Your body as an 80/20 diagnostic 56:02 The free assessment, plus a live activation Links Watch it on YouTube: https://youtu.be/5cf_nfY7lOo  Full episode show notes: https://outliyr.com/280 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if the spot that hurts is not actually the problem? After 26 years fixing bodies, David Starbuck Smith says most chronic pain starts somewhere else entirely. Exercise therapist and functional anatomist David Starbuck Smith rebuilt the bodies of NFL, ATP, and WTA athletes and consulted for the San Francisco 49ers. In this episode he explains why non-traumatic pain is almost always a whole-body alignment problem, how to spot your own imbalances at home, and why varied movement keeps you strong and pain-free as you age. Meet our guest David Starbuck Smith is a former pro tennis player turned exercise therapist, trained under Pete Egoscue. He is an expert on posture, alignment, and joint mechanics, has written three books on relieving pain, and now coaches clients worldwide through The Daily Motion Lab. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways The site of pain is rarely the cause; imbalance and compensation move it around the body. An MRI tells you the what, not the why, and misses the imbalance behind the injury. Roughly 80 to 95 percent of people get back pain; non-traumatic pain means an imbalance. Strengthening an imbalanced body only deepens the imbalance. A painful muscle is usually switched off, not weak; alignment brings the strength back. Movement variety, more than any single workout, is what a Harvard finding links to longevity. Age is not the cause of decline; lost motion is. Episode highlights 0:00 The place that hurts isn't where you broke down 9:06 80% of us get back pain: it's imbalance 21:02 The at-home mirror self-test 27:30 Why 'stand up straight' never sticks 40:56 How emotional stress becomes physical pain 53:41 We just cured your DNA 58:41 Prevention, variety & living longer Links Watch it on YouTube: https://youtu.be/QeNTrAdjuEo  Full episode show notes: https://outliyr.com/279 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if fibromyalgia, chronic fatigue, and chronic Lyme were not separate diseases at all, but one problem wearing different masks? Dr. Bill Rawls, MD, co-founder and medical director of Vital Plan, got so sick in his forties that conventional medicine could not reach him. He rebuilt himself from the cell up with herbs, and he now argues that your cells carry dormant microbes for decades, and that health comes down to whether those cells can keep clearing house. This episode lays out the cellular picture of chronic illness and the herbs that hold it in check. Meet our guest Dr. Bill Rawls, MD is a number-one bestselling author (Unlocking Lyme, The Cellular Wellness Solution) and the founder of Vital Plan, where he developed the RESTORE180 herbal protocol. After a chronic-Lyme crisis, he restored his health through botanical medicine and has spent over a decade piecing together the research on how cells and microbes drive chronic illness. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Chronic illness is one problem in disguise: cellular stress impairs autophagy and lets dormant microbes reactivate. About 60% of all microbe mass on Earth is dormant at any moment. 95% of people carry Epstein-Barr and at least 60% carry Toxoplasma, usually without symptoms. Antibiotics depend on fast growth, so they struggle against slow microbes like Borrelia. Herbs carry hundreds of compounds, so microbes never develop resistance, and they spare the gut and mitochondria. Adaptogenic antimicrobials like Japanese knotweed and cat's claw can be taken long term. Start with turmeric, boswellia, and reishi on a base of sleep, plant diversity, and movement. Episode highlights 1:54 Why cells are the real root of chronic illness 15:21 Dormant microbes living in your cells for decades 24:53 Autophagy: your cells' cleanup crew and defense 46:45 Why antibiotics fail against stealth microbes 51:20 The boiling point and rebuilding with herbs 58:38 Adaptogens vs adaptogenic antimicrobials 1:10:14 Where to start: herbs, dose, and the basics Links Watch it on YouTube: https://youtu.be/V4GoxN31sUQ  Full episode show notes: https://outliyr.com/278 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if the one signal you can't fake is already in your pocket? Your voice changes when you are stressed, tired, or run down, and Alex Fredericks built a company that reads it. ToneWell founder Alex Fredericks explains how a 30-second voice clip is analyzed against a static database to extrapolate about 1,000 biomarkers, delivered as a prioritized wellness report in minutes. No blood, no wearable. Meet our guest Alexander B. Fredericks is a growth engineer and the founder of ToneWell and AECC Group. After more than twenty years in brand, media, and the music business, he turned the voice into a wellness analytic, built on a 30-second Performance Readiness Scan and validated by his co-founder Dr. Bear Walker, a double-PhD pioneer of bio-tracking machines. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways A 30-second voice clip can extrapolate around 1,000 biomarkers, with a report in under five minutes. Voice is topical: readable in the moment, unlike a blood panel that takes an appointment, a draw, a lab, and a callback. Your baseline is stable, but your in-the-moment values shift, so a single lab draw can miss both. A hard training day burns through magnesium, potassium, zinc, boron, and copper. A wearable gives you a sleep score but not the reason, like a low magnesium form. The science of frequency is old; what is new is the delivery speed. Alex uses ToneWell mostly as his own recovery tool. Episode highlights 1:38 What ToneWell reads in 30 seconds 2:50 How your voice becomes data 22:35 Baseline versus the moment 24:53 Minerals that stress burns 40:10 Nick's own scan 53:31 Meet the BioTracker 58:13 Wellbeing over wellness Links Watch it on YouTube: https://youtu.be/XjKp0wcbhmQ  Full episode show notes: https://outliyr.com/277 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Why does every diet eventually end with you back where you started? Ben Fudge says the problem was never your willpower. It was the plan. Ben Fudge, head coach of the Elite program at Trevor Kashey Nutrition and a former Army Ranger, reveals Cognitive Nutrition: a behavior-first method that turns new eating habits into skills that finally hold. He walks through the SRO model, why you track before you target, and how to stay calm when the cookie is right in front of you. Meet our guest Ben Fudge is the head coach of the Elite program at Trevor Kashey Nutrition (TKN). A former Army Ranger with four overseas deployments, he brings military-grade discipline and structure to coaching built on TKN's Cognitive Nutrition method, developed by Dr. Trevor Kashey. Ben has helped clients lose over 100 pounds in a single year and coaches high-performing men to match their body to the life they have already built. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Calling it a "diet" implies an end date, and that framing is what causes the rebound. Behavior change, not willpower, is what makes new habits stick. The SRO model (Stimulus, Response, Outcome) inserts time and space before you react. Track everything to the gram first, before setting any target. Fix protein and calories, then run the big four: sleep, hydration, nutrition, activity. One slip is not total failure. Do not slash the other three tires over one flat. Rehearse high-risk moments ahead of time instead of relying on willpower. Reinforce the behavior, not the outcome, and stop rewarding yourself with food Episode highlights 0:00 Why calling it a 'diet' guarantees you quit 1:20 What cognitive nutrition actually is 7:21 The SRO model: stimulus, response, outcome 12:56 Start by tracking everything 17:24 The big 4: sleep, hydration, nutrition, activity 35:26 Rehearse the party before you walk in 1:02:11 How to work with Ben Fudge & TKN Links Watch it on YouTube: https://youtu.be/zhM0SDa5-gM  Full episode show notes: https://outliyr.com/276 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Your annual physical came back "normal," so why do you still feel foggy, tired, and stuck? Dr. Adrijana Kekic says your biology has probably been drifting for years before any standard test notices. Former Mayo Clinic pharmacogenomics specialist and Futurome founder Dr. Adrijana Kekic reveals what a standard 30 to 100 marker panel misses, how multi-omics testing catches metabolic drift early, and why women age differently after 40. After a preventable pulmonary embolism nearly killed her, she rebuilt her own health and now maps cellular aging for people who look fine on paper. Meet our guest Dr. Adrijana Kekic is a pharmacist and nutritionist trained in genetics, one of the first pharmacogenomics clinical specialists at Mayo Clinic and winner of its 2023 Innovation Award. She founded Futurome, a precision health intelligence company that reads thousands of biomarkers to map cellular aging, with a special focus on female biology. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Standard panels lean on late markers; fasting insulin and HOMA-IR flag metabolic trouble years earlier. Multi-omics testing reads thousands of markers across genomics, proteomics, metabolomics, and microbiome. Cellular aging spikes around 40 and 60, the windows where personalization pays off most. The highest mitochondrial density in women sits in the ovaries; decline can surface there before any blood test. Perimenopause is estrogen swinging up and down, not just falling; it hides on standard labs. Women make about 50% less gut serotonin than men, so fasting protocols should differ by sex. Foundation first: sleep, magnesium, vitamin D, movement, and a CGM before advanced interventions. Episode highlights 0:00 Normal labs, hidden aging 6:09 What standard bloodwork misses 18:24 The two aging cliffs at 40 & 60 25:33 The perimenopause you don't notice 30:27 The ICU wake-up call 40:40 Foundation before shiny objects 46:18 Why men & women differ Links Watch it on YouTube: https://youtu.be/1P-vuKmzvtw  Full episode show notes: https://outliyr.com/275 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Can you reverse type 2 diabetes without drugs? Chris Reade did, and it came down to one nutrient most people never think about. He took his A1C from a diabetic 9.3 back to normal, no medication, no extreme dieting. In this episode he breaks down the soluble-fiber approach and the simple habits that made it stick for almost a decade. Meet our guest Chris Reade is a former software CEO with no medical background who reversed his own type 2 diabetes after an accidental blood test caught his blood sugar sky-high. He now shares a science-first, practical plan built on soluble fiber, walking, sleep, and stress control in his book Beating Diabetes. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Soluble fiber (edamame, chickpeas, beans, broccoli, oats) slows digestion and blunts glucose spikes. Starting a meal with edamame keeps blood sugar flat and curbs your appetite. Chris dropped nearly 25 pounds in 6 months with no portion control. A short post-meal walk lowers blood sugar as much as a supplement. Berberine matched metformin for him; cinnamon and apple cider vinegar were busts. 1 gram of visceral fat on the pancreas can trigger type 2 diabetes, and losing it can reverse it. Use a CGM short-term to learn, then avoid the long-term analysis paralysis.   Episode highlights 0:00 The accidental blood test 4:06 The one nutrient: soluble fiber 6:09 Edamame before sushi 21:24 Berberine vs cinnamon 7:44 The post-meal walk 43:35 One gram of fat 49:24 Where to find Chris Links Watch it on YouTube: https://youtu.be/LRT8c3T09Ko  Full episode show notes: https://outliyr.com/274 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Why does the average dog now live 7 fewer years than one did in the 1970s? Holistic veterinarian Dr. Judy Morgan says the answer is sitting in the food bowl, and it's fixable. With 36 years in practice and a base in traditional Chinese veterinary medicine, Dr. Judy Morgan explains how food became the foundation of her work, why dry kibble fails dogs and cats, and the simple whole foods that add years of healthy life. This is a rare episode on how pet health and human health mirror each other. Meet our guest Dr. Judy Morgan (DVM, CVA, CVCP, CVFT) is an integrative veterinarian, acupuncturist, chiropractor, food therapist, and best-selling author with more than 40 years in animal health. Named IAOTP Holistic Veterinarian of the Decade for 2024, she runs Dr. Judy Morgan's Naturally Healthy Pets, helping pet parents worldwide heal with food and natural therapies instead of defaulting to chemicals and processed food. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways The average medium-sized dog's lifespan fell from 17 years to about 10, which Dr. Morgan considers reversible. Dry kibble is capped near 30% meat and can be 50 to 60% carbohydrates, which pets do not require. Roughly 40% of pet-food ingredients are upcycled byproducts, and unnamed "meat meal" can be any species. Pets test 10 to 25 times higher than their owners for cancer-linked household chemicals. Low phosphorus and high moisture matter far more than restricting protein in kidney disease. Cheap whole-food toppers like sardines, eggs, blueberries, and pumpkin make a real difference. Delaying spay or neuter protects joints, hormones, and longevity in large breeds.   Episode highlights 00:00 The dog healed by food, and the owners who lost 200 pounds 06:37 Why moisture matters more than the bag admits 26:53 What really goes into "meat meal" 32:29 Pets need zero carbohydrates 42:12 Lifespan 17 to 10, and why it's reversible 44:45 The cheap whole foods to add today 59:04 The spay and neuter timing rethink Links Watch it on YouTube: https://youtu.be/mU0sdbXCj3s  Full episode show notes: https://outliyr.com/273 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Performing random acts of kindness can calm your parasympathetic nervous system and improve overall longevity. Full episode: https://outliyr.com/podcast/nervous-system-connection-longevity-framework-blair-lacorte

What if your brain fog, anxiety, and memory lapses all trace back to one thing: an inflamed brain? Naturopathic physician Dr. Jaquel Patterson, ND, MBA joins Nick Urban to explain neuroinflammation in plain language and map the root causes behind it. With 16 years of clinical experience in Lyme disease, autoimmune conditions, and integrative psychiatry, she connects the gut, hormones, chronic infections, and environmental toxins to the same inflammatory loop, and lays out how to calm it naturally. Meet our guest Dr. Jaquel Patterson is an internationally recognized naturopathic physician, three-time Amazon bestselling author, and founder and CEO of Fairfield Family Health, a multidisciplinary practice in Connecticut with 9 doctors offering telemedicine nationwide. She has a TEDx talk on root-cause medicine coming soon. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Neuroinflammation shows up as brain fog, poor focus, memory lapses, and mood swings, an inflamed brain "on fire" The blood-brain barrier keeps out about 98% of solutes until chronic inflammation breaks it down About 90% of your serotonin is made in the gut, linking gut health directly to mood and cognition Deep sleep runs the brain's lymphatic clean-out, and sauna lowers CRP and IL-6 A standard CBC can miss iron deficiency for 3 to 6 months Curcumin downregulates IL-6, and phosphatidylserine lowers cortisol while sharpening focus Small, consistent micro-moments beat dramatic overhauls that never stick   Episode highlights 01:09 The "brain on fire" explanation 02:30 Microglia as your brain's garbage men 11:51 Leaky gut, leaky brain 17:13 Sleep and sauna to lower inflammation 27:58 The iron test most doctors skip 48:31 Curcumin for mood and IL-6 57:02 The cheapest thing you can do for your brain Links Watch it on YouTube: https://youtu.be/yWFYfc80Q1U  Full episode show notes: https://outliyr.com/272  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick