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In this episode of Scientists, Unedited, Luigi Naldini, PhD, Professor of Cell and Tissue Biology and of Gene and Cell Therapy at the San Raffaele University School of Medicine and Scientific Director of the San Raffaele Telethon Institute for Gene Therapy, joins host Eirini Vamva, PhD, for a discussion on his story. Dr. Naldini, a pioneer of lentiviral vectors, reflects on the unexpected path that led him to gene therapy and helped turn a bold scientific idea into a clinical reality. He discusses the risks, setbacks, collaborations, and family support that shaped his career, as well as the future of gene therapy and why meaningful scientific progress requires persistence, teamwork, and time. Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

In this episode of The Issue, CEO of Life Biosciences Jerry McLaughlin joins hosts Sanjay D’Souza, PhD and Jason West, PhD for a discussion on how epigenetic reprogramming could restore function in aging and injured cells. He explains the science behind ER-100, an investigational gene therapy now in a Phase 1 trial for optic neuropathies, and explores the broader promise of targeting age-related diseases to help improve quality of life. Music: ‘Bright New Morning’ by Steven O’Brien – released under CC-BY 4.0. https://www.steven-obrien.net/  Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

This episode, hosted by Daniel Stone, Associate Editor-in-Chief of Molecular Therapy Advances, focuses on the article, Normothermic perfusion of human livers for profiling lentiviral vector pharmacokinetics and transduction. Listen as Robert Carlisle and Brannon Nicholls from the University of Oxford discuss their approach to studying lentiviral vector transduction and pharmacokinetics in the human liver ex vivo.  Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

In this episode of Scientists, Unedited, host Eirini Vamva, PhD, talks with Bruce Levine, PhD, about his personal life and career in cell therapy. Dr. Levine talks about finding his way into immunology, learning from pivotal mentors, and following the unexpected opportunities that led him to the forefront of cell therapy. He reflects on the patients who inspired his work and the teamwork behind major breakthroughs. He also shares the story behind a CAR-T song he helped write and talks about some of the things that make him who he is outside the lab, including cycling and his love of wildlife and dancing. Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

Molecular Therapy Oncology has released a new special collection, Advancements in Pediatric Cancer Therapy. Listen in as guest editor Nirali Shah and Editor-in-Chief Timothy Cripe discuss articles in this special collection, which covers the history, current landscape, and future direction of pediatric cancer therapy. Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.au Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

In this episode of The Issue, Sara Johnson Davis, Senior Director of Government Affairs at Ardelyx and former Vice President, Head of Patient Advocacy & Policy at Fulcrum Therapeutics, joins host Sanjay D’Souza, PhD, to discuss the essential role of patient advocacy in cell and gene therapy. The conversation covers the evolving role of patient advocacy in drug development, from early research and clinical trial design to policy, commercialization, and access. Sara shares lessons from the sickle cell disease community, reflects on the transition of gene editing from experimental science to approved therapy, and explains why trust, infrastructure, and policy are essential to ensuring transformative treatments actually reach patients. Music: ‘Bright New Morning’ by Steven O’Brien – released under CC-BY 4.0. https://www.steven-obrien.net/ Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

Recorded live at the ASGCT 2026 Annual Meeting in Boston, Le Cong, PhD joins hosts Jason West, PhD and Sanjay D’Souza, PhD for a discussion on his work in genome engineering and the early development of CRISPR/Cas9. The three then dive into Dr. Cong’s use of artificial intelligence tools developed and currently used by his lab. Dr. Cong is a 2026 recipient of ASGCT’s Outstanding New Investigator Awards. Music: ‘Bright New Morning’ by Steven O’Brien – released under CC-BY 4.0. https://www.steven-obrien.net/ Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

This episode focuses on Molecular Therapy’s upcoming special issue, the biological clock of aging and the possibility of lifespan extension. Listen in as Dr. Joseph Glorioso, Editor-in-Chief of Molecular Therapy, discusses the molecular mechanisms that drive senescence, determine longevity, and contribute to healthy aging with the guest editors of the special issue, Dr. Christin Glorioso from NeuroAge Therapeutics and Dr. John Bell from the University of Ottawa. Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.au Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

In this episode recorded live at the ASGCT 2026 Annual Meeting in Boston, host Eirini Vamva, PhD interviews Anna Maurer, PhD of the University of Michigan. Dr. Maurer shares her story of growing up in Michigan and how her path led her to Harvard Medical School. She discusses her work in AAV and gives advice to individuals looking to enter the field of cell and gene therapy. Music: 'Dreamer' by Steven O'Brien – Released under CC-BY 4.0. https://www.steven-obrien.net/ Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

Recorded on site at the ASGCT 2026 Annual Meeting in Boston, host Sanjay D’Souza, PhD, talks with Fyodor Urnov, PhD, about the evolution and future of gene editing. One of the 2026 ASGCT Catalyst Award co-recipients, Dr. Urnov, talks about his work in gene editing and discusses the need for collaboration in the field to bring more cell and gene therapies to patients. Music: ‘Bright New Morning’ by Steven O’Brien – released under CC-BY 4.0. https://www.steven-obrien.net/ Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

This episode, recorded at the ASGCT 2026 Annual Meeting in Boston, focuses on Molecular Therapy Advances’ upcoming special issue, Beyond prevalance: How rare diseases are reshaping therapeutic innovation. Listen as Editor-in-Chief of Molecular Therapy Advances, Dr. Mohamed Abou-el-Enein, discusses the evolution of therapeutic development for rare diseases with guest editors Drs. Jennifer Adair, Claire Booth, Terence Flotte, and Donald Kohn. Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.au Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

Scientists, Unedited is a monthly podcast hosted by Eirini Vamva, PhD, that spotlights the people behind scientific breakthroughs – their journeys, motivations, and lives beyond the lab. Each episode begins with personal stories, explores passions outside of science, and closes with an accessible conversation about the guest’s work for a general audience. In this first episode, Dr. Vamva sits down with ASGCT President Matthew Porteus, PhD, for a conversation about the winding path that brought him full circle back to Stanford University. The conversation offers a candid look at the personal experiences and motivations that have shaped Dr. Porteus’s career and his leadership in the field of cell and gene therapy. Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

Recorded on site at the ASGCT 2026 Annual Meeting in Boston, this mini-series introduces listeners to ASGCT members and the work driving progress across the cell and gene therapy field. In each episode, members are invited to share their backgrounds, discuss the current state of the field, and reflect on the value of ASGCT membership. This series of brief, engaging conversations will help listeners get to know the people, perspectives, and ideas shaping the ASGCT community. In this episode, host Ben McLeod of the ASGCT Communications Committee talks with Godwin Iroanya of the University of Missouri. Godwin shares his current work and research and how ASGCT membership has helped his career, including the Molecular Therapy Family of Journals and the Society’s pilot Mentor Program. Music: 'Origami' by Scott Buckley – released under CC-BY 4.0. www.scottbuckley.com.au Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

In this episode of The Issue, new co-hosts Jason West, PhD, and Sanjay D’Souza, PhD, turn the mics on themselves to introduce one another to listeners. Recorded live at the ASGCT 2026 Annual Meeting in Boston, this episode invites listeners to get to know the new co-hosts as they share their backgrounds, ask each other questions, and share how listeners can get involved with future content of The Issue podcast. Music: ‘Bright New Morning’ by Steven O’Brien – released under CC-BY 4.0. https://www.steven-obrien.net/ Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.

Recorded on site at the ASGCT 2026 Annual Meeting in Boston, this mini-series introduces listeners to ASGCT members and the work driving progress across the cell and gene therapy field. In each episode, members are invited to share their backgrounds, discuss the current state of the field, and reflect on the value of ASGCT membership. This series of brief, engaging conversations will help listeners get to know the people, perspectives, and ideas shaping the ASGCT community. In this episode, host Ben McLeod of the ASGCT Communications Committee talks with Dylan Bechtle, Director of Regulatory Policy in North America at Johnson & Johnson. Dylan shares how ASGCT membership has been valuable to his career in the regulatory space, both through its community and its resources for staying up to date with the CGT field. Music: 'Origami' by Scott Buckley – released under CC-BY 4.0. www.scottbuckley.com.au Show your support for ASGCT!: https://asgct.org/membership/donate See omnystudio.com/listener for privacy information.