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One in Six Billion

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Rating
★★★★★
5
from
6 reviews
This podcast has
52 episodes
Language
English
Date created
2023/11/13
Latest episode
2025/10/28
Average duration
30 min.
Release period
15 days

Description

A podcast about diabetes and genes hosted by Andrew Hattersley and Maggie Shepherd.

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Special Episode 8: Steve Chapman, Andrew Hattersley and Maggie Shepherd. Final reflections on making the One in Six billion podcast.
2025/10/28
In the final episode of the One in Six Billion podcast Andrew and Maggie reflect with producer Steve Chapman on the fun they have had making 51 podcasts with 70 guests in the past 2 years. Send a text
Series 4 Episode 8. Rohini Bajekal and Shivani Misra. The challenge of diagnosing monogenic diabetes in South Asians
2025/10/14
Rohini Bajekal describes how she had years of receiving inappropriate lifestyle advice before Glucokinase MODY was diagnosed.  Dr Shivani Misra’s research has shown that failure to diagnose monogenic diabetes is even common in South Asians than in the white European population. Send a text
Series 4 episode 7. Sarah Richardson. Small extra-islet beta cells matter
2025/09/30
Sarah Richardson talks about her new exciting research on insulin producing beta-cells that are single cells or small clusters rather than in islets.  These extra-islet beta-cells make up most of the insulin producing capacity of the pancreas in young children and are particularly susceptible to immune attack in Type 1 diabetes.  This important research explains why the loss of insulin producing cells in Type 1 diabetes is more severe in young children and informs future work on treating and preventing Type 1 diabetes. Send a text
Series 4 episode 6: Hannah Robinson and Nick Thomas. Taking immunotherapy to delay adult-onset Type 1 diabetes
2025/09/16
Hannah Robinson was the first adult in the UK to be given the new immunotherapy drug Teplizumab, which aims to slow down the development of type 1 diabetes. Hannah had multiple pancreatic autoantibodies and hence is on the path to developing Type 1 diabetes (Series 4 Episode 3). Her consultant, Nick Thomas, arranged 14 consecutive daily hospital visits for her to receive the drug through a drip.  Send a text
Series 4 episode 5. Jerry Gore and Rob Andrews. Living life on the edge with Type 1 diabetes.
2025/09/02
Jerry Gore has always lived life on the edge; he had tackled some of the highest, and most inhospitable mountain climbs in the world before he was diagnosed with Type 1 diabetes aged 40.  His Type 1 diabetes has not held him back and he has learnt how to live well with his Type 1 diabetes when climbing at extreme altitude and bitter cold.  He helps people living with Type 1 diabetes throughout the world, especially in S E Asia as co-founder of Action4Diabetes (A4D). Rob Andrews is a national expert helping people with Type 1 diabetes to adapt their diabetes care so they can do any extreme activity including mountaineering, long distance swimming, and endurance cycling. Send a text
Series 4 episode 4. Chris Bright and Rob Andrews. Type 1 diabetes and Elite Sport.
2025/08/19
Chris Bright was diagnosed with Type 1 diabetes aged 8 but this did not stop him having a very successful football career including playing international futsal for Wales. He describes the challenges he faced and how he over came them.  He has established The Diabetes Football Community that supports football for everyone living with Type 1 diabetes. Dr Rob Andrews helps people with Type 1 diabetes compete in all sports at the highest level.  He has set up the Exercise for Type 1 Diabetes (EXTOD) education program for patients and healthcare professionals. Send a text
Series 4 episode 3: Hannah Robinson and Nick Thomas
2025/08/05
First steps in delaying adult-onset Type 1 diabetes When Hannah Robinson was diagnosed with gestational diabetes and found to have islet auto-antibodies she was recognised as being on the path to future Type 1 diabetes.  With help from her diabetes consultant, Dr Nick Thomas, she became the first adult in the UK to be given Teplizumab, a new treatment that delays the onset of Type 1 diabetes. Send a text
Series 4 Episode 2. Rachel Besser. Identifying children before they develop Type 1 diabetes
2025/07/22
Dr Rachel Besser explains how new treatment options means it is now important to identify children before they get symptomatic Type 1 diabetes.  Rachel is working to make sure testing for risk of Type 1 diabetes is done in the best way for children and their families. Send a text
Series 4 Episode 1. Richard Oram. First steps towards preventing Type 1 diabetes
2025/07/08
Richard Oram explains how recent advances have meant we can now delay type 1 diabetes with immunotherapy.  To do this we need to be able to identify people at very high risk of developing Type 1 diabetes.  Richard thinks genetic analysis could play a part in this identification.   Send a text
Series 3 Episode 17. Jennifer and Helen. Prader Willi syndrome: hunger that never goes away
2025/06/24
Jennifer and her mother Helen explain how being born Prader Willi syndrome has had a lifelong impact.  One challenge is that Jennifer is continually hungry, and so limiting access to food is needed at all times.  Send a text
Special episode 7. Maggie Shepherd (part 2). Inspirational nurse researcher and educator
2025/06/10
Professor Maggie Shepherd reflects back on her career and how she made the massive steps from being a clinical nurse to becoming a nationally leading researcher and educator. Send a text
Special episode 6. Andrew Hattersley (part 2). Building the Exeter diabetes research team
2025/05/27
Andrew Hattersley describes how teamwork and mutual support has helped the Exeter diabetes research team expand and flourish over the past 30 years Send a text
Series 3 Episode 16. Grace Bervoets and Amanda Stride. Cystic Fibrosis related Diabetes
2025/05/13
Grace Bervoets talks about living with cystic fibrosis and cystic fibrosis related-diabetes.  Amanada Stride, who works as a diabetes consultant helping people with cystic fibrosis related-diabetes, explains the many challenges of this unusual type of diabetes. Send a text
Series 3 Episode 15. Tom Staniford. MDP syndrome
2025/04/29
Tom Staniford talks about living with the MDP syndrome, an extremely rare genetic condition. MDP syndrome includes Mandibula hypoplasia, Deafness, and Progeroid features amongst its widespread features. Tom developed Type 2 diabetes as a teenager because of a loss of fat under the skin (lipodystrophy) despite being very thin and active.  Tom has used his communication and media skills to help other people with MDP syndrome get diagnosed and receive the right care. Send a text
Series 3 Episode 14: Farah O'Regan and Matt Johnson. Down syndrome and very young onset diabetes
2025/04/15
Farah O'Regan talks about how her son who had Down syndrome and a severe congenital heart condition needing surgery diagnosed in pregnancy and then developed Type 1 diabetes on day 2 of life.  In early childhood he was diagnosed with 2 more autoimmune conditions, coeliac disease and hypothyroidism.  Researcher Matt Johnson explains his research which has established that Down syndrome directly results in very early-onset autoimmune diabetes.  Send a text

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