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Send us Fan Mail Can a GLP-1 actually change your fertility? For many women with PMOS (formerly called PCOS), the answer may be yes, and that changes everything from birth control to baby planning. Reproductive endocrinologist Dr. Sasha Hakman walks through the whole arc: how GLP-1-assisted weight loss can help restart ovulation, why the guidance is still to stop two months before trying to conceive, what early data suggests if you get pregnant while on one, and why some birth control pills may be less reliable on these medications. Then she and Ana get honest about prenatals, breastfeeding, the pressure to "bounce back" after a baby, and a pattern she has noticed in a handful of men's semen analyses. IN THIS EPISODE - What a fertility doctor does besides IVF - How PMOS (formerly PCOS) disrupts ovulation, and how GLP-1-assisted weight loss can help restore it - Why you still stop a GLP-1 two months before trying to conceive - Metformin as a bridge, and why pregnancy weight gain can be harder after stopping - What early data suggests about pregnancies that happen while on a GLP-1 - What to do if you find out you're pregnant on a GLP-1 - Early, experimental reports from women with endometriosis - Why birth control pills may be less reliable on a GLP-1, and which options are less affected - How GLP-1s can make irregular cycles more predictable - Why every woman of reproductive age should take a prenatal, and the folic acid vs. methylfolate debate - Prenatals after 60 and the iron question - Breastfeeding, milk supply, and when to restart a GLP-1 after delivery - The postpartum "bounce back" pressure, and why you should give yourself time - GLP-1s and men's fertility, plus why men should prepare at least three months before trying ABOUT THE GUEST Dr. Sasha Hakman, MD, is a Los Angeles-based, double board-certified physician in Obstetrics and Gynecology and Reproductive Endocrinology and Infertility. She cares for patients across the full range of reproductive medicine, from fertility testing and optimization before trying to recurrent pregnancy loss and IVF. She is also the host of the podcast Trying with Dr. Hakman, where she covers fertility, hormones, pregnancy, postpartum, and women's health. CONNECT WITH DR. SASHA HAKMAN Website: https://www.sashahakmanmd.com Instagram: https://www.instagram.com/sashahakmanmd/ YouTube: https://www.youtube.com/@sashahakmanmd Trying with Dr. Hakman (podcast on YouTube): https://www.youtube.com/@tryingpodwithdrhakman SPONSORS This episode is brought to you by Tyde Wellness, the GLP-1 provider Ana uses, with nutrition guidance built for GLP-1s, consults with independent licensed providers, and a care team that answers when something comes up. Go to https://tydewellness.com/GLP1Hub and use code GLP1Hub50 for $50 off your first month. This episode is also brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours. CHAPTERS 00:00 Can a GLP-1 change your fertility? 00:31 Intro 01:42 Welcome, Dr. Sasha Hakman 02:10 What a fertility doctor actually does 03:37 GLP-1s, PMOS, and ovulation 06:52 Why you stop two months before trying to conceive 08:04 Metformin and pregnancy weight after stopping 09:29 What the data shows if you conceive on a GLP-1 09:57 Pregnant on a GLP-1? What to do next 10:47 Endometriosis and early reports 12:10 Birth control that may be less reliable on a GLP-1 13:27 GLP-1s and your menstrual cycle 15:16 Sponsor: Tyde Wellness 16:31 Eating for pregnancy when your appetite is small 18:01 Why every reproductive-age woman needs a prenatal 18:35 Folic acid vs. methylfolate 20:54 Prenatals after 60 and the iron question 22:41 Breastfeeding and restarting a GLP-1 25:36 The postpartum bounce-back pressure 29:24 Sponsor: Timeline 30:32 GLP-1s and men's fertility 32:19 Why not everyone needs a GLP-1 33:26 Men's prenatals and the three-month window 34:42 Where to find Dr. Hakman 35:46 Ana's final thoughts MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail After gastric bypass, some people make so much of their own GLP-1 that their blood sugar rockets after a meal and then crashes, and the juice or glucose tabs meant to rescue them can restart the whole cycle. Stanford endocrinologist Dr. Marilyn Tan explains post-bariatric hypoglycemia, a condition many patients live with for years before anyone names it, and whether GLP-1 medications make sense after surgery for weight regain. Then she shares phase 3 results for avexitide, an investigational drug that works in the opposite direction from the GLP-1 medications everyone is talking about. **IN THIS EPISODE** - Hypoglycemia vs. hyperglycemia in plain language, including what "level 3" low blood sugar means - What your body's own GLP-1 does after you eat, and why gastric bypass and sleeve surgery amplify it - Why diabetes can resolve within days of surgery, before the weight comes off - Whether GLP-1 medications are safe to use after bariatric surgery for weight regain - What post-bariatric hypoglycemia (PBH) is, who tends to get it, and why it often shows up six months or more after surgery - The spike-then-crash pattern one to three hours after a carb-heavy meal - Why the usual low blood sugar advice can backfire for PBH, and what helps stabilize instead - The strict PBH diet (about 30 grams of carbs per meal, 15 per snack) and how it can tip into malnutrition - Why PBH is underdiagnosed, and the new ICD-10 diagnosis code - Inside the phase 3 LUCIDITY trial of avexitide, a GLP-1 blocker that is not FDA approved - What GLP-1 agonists do and don't do for people who already have PBH - What's next for avexitide and who else it may help **ABOUT THE GUEST** Dr. Marilyn Tan, MD, FACE, FACP, is double board certified in Endocrinology and Internal Medicine. She is a Clinical Professor of Medicine at Stanford University School of Medicine and Chief of the Endocrine Clinic at Stanford Health Care. Her clinical focus is outpatient and inpatient diabetes management, and her research includes diabetes and post-bariatric hypoglycemia. She is also actively involved in resident and fellow education and mentorship. **CONNECT WITH DR. MARILYN TAN** Stanford Health Care profile: https://stanfordhealthcare.org/doctors/t/marilyn-tan.html **SPONSOR** This episode is brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours. **CHAPTERS** 00:00 Cold open 00:22 Ana's intro 01:23 Welcome, Dr. Marilyn Tan 02:30 Low vs. high blood sugar, explained 04:04 What GLP-1 does when you eat 04:27 Why gastric bypass supercharges your GLP-1 response 07:02 GLP-1, the brain, and appetite after surgery 09:39 Can you take a GLP-1 after bariatric surgery? 10:49 Who gets post-bariatric hypoglycemia 12:05 The spike and the crash, symptoms to know 13:27 Sponsor break, Timeline 14:22 Why juice and glucose tabs can backfire 14:52 Stabilizing lows and the strict PBH diet 17:12 How common PBH is, and its new diagnosis code 19:05 Inside the phase 3 avexitide trial 20:51 How a GLP-1 blocker works 22:04 Do GLP-1 medications help or hurt PBH? 24:56 From Ana, the Beyond the Shot guide 26:04 The results, 55% fewer serious lows 26:51 What happens next for avexitide 27:39 Side effects and daily injections 29:00 Where to learn more 29:50 Beyond bariatric surgery, who else this could help 31:08 Closing MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail Does a dinner out or a big trip ever feel like it could undo your progress on a GLP-1? Registered dietitian Holly Larson joins Ana to explain why a GLP-1 is a tool, not a diet, and how to enjoy restaurants and vacations without feeling terrible the next day. You'll learn how to read a menu, what to do with your medication when you travel, and the one word that tells you diet culture is doing the talking. **IN THIS EPISODE** - Why a GLP-1 is a tool, not another restrictive diet - How to spot the "should" voice and talk back to it - Ordering at a special-occasion restaurant: protein, appetizers as mains, and the foods most likely to cause the "icks" - Being mindful (not rigid) with bread baskets, alcohol, and fancy coffee drinks - Everyday restaurant eating: 25 to 30 grams of protein and plenty of fiber - Continuing or pausing your dose for a trip, and why that decision belongs with your prescriber - Traveling with your pen: insulin cooler cases, carry-on only, TSA, and international limits - Planning your vacation meals around the one you're most excited about - Packing for hydration and GI comfort: electrolytes, prunes, and backup medications **ABOUT THE GUEST** Holly Larson is a registered dietitian with almost two decades of experience. She runs a virtual private practice in Ohio supporting women, especially those using GLP-1 medications, with a food-first, no-shame approach. **CONNECT** Website: https://hollylarsonnutrition.com Instagram: @hollylarsonnutrition **SPONSOR** Tyde Wellness is the GLP-1 provider Ana uses herself. Visit https://tydewellness.com/GLP1Hub and use code GLP1Hub50 for $50 off your first month. **CHAPTERS** 00:00 Skip a dose for a food trip? 00:32 Welcome and episode preview 01:25 Meet Holly Larson 03:16 A GLP-1 is a tool, not a diet 05:20 Quieting the "should" voice 09:07 How to order at a special restaurant 10:51 Bread baskets and alcohol 12:05 Sponsor: Tyde Wellness 13:04 Eating out every day 14:48 Drinks and the hidden-calorie salad 16:09 Your medication and travel 18:07 Carrying your pen, TSA, and international trips 21:30 How to eat on vacation 23:22 Ana's Beyond the Shot guide 24:23 Balancing breakfast, steps, and indulgent dinners 26:15 Hydration and GI prep for travel 29:37 Final thoughts and where to find Holly MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail If the scale has stalled or you're worried about losing muscle on a GLP-1, that number may not be telling you the whole story. Fitness coach and competitive powerlifter Andrew Menechian explains why body composition matters more than your weight or BMI, how to set a protein target that actually fits your body, and the minimum strength training it takes to hold on to muscle. You'll also hear why he thinks cutting calories lower and lower backfires, and the diet-break approach he uses instead. **IN THIS EPISODE** - What body composition means, and why two people at the same weight can look completely different - Why BMI misses people who are "skinny fat" and labels muscular athletes as obese - Beginner gains: why people new to strength training can build muscle and lose fat at the same time - The two things that protect muscle on a GLP-1: protein and resistance training - How to set a protein target based on lean body mass instead of total body weight - How much strength training it takes to maintain muscle versus build it - Why training first thing in the morning makes the habit easier to keep - Simple options for older adults and people with injuries or physical limitations - Muscle first or fat loss first when you're already at a healthy weight - Metabolic adaptation, reverse dieting, and his diet-break strategy for plateaus **ABOUT THE GUEST** Andrew Menechian is an online health coach and head of fitness at Fit Commit, with about 15 years of coaching experience. He is a former head coach at the Clean Health Fitness Institute and former education manager at Fitness Playground in Australia. A competitive bodybuilder and powerlifter, he won the 2015 IFBB Australasian Men's League title and unofficially broke an Australian under-90 kg deadlift record. **CONNECT WITH ANDREW MENECHIAN** FitCommit Website: https://fitcommit.ai Instagram: https://www.instagram.com/fitcommitai/ YouTube: https://www.youtube.com/@fitcommitai Andrew Menechian Instagram: https://www.instagram.com/andrewmenechian/ YouTube: https://www.youtube.com/@andrewmenechian X: https://x.com/andrewmenechian LinkedIn: https://www.linkedin.com/in/andrewmenechian/ **SPONSOR** This episode is brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours. **CHAPTERS** 00:00 Preview: why the scale isn't the whole story 00:25 What's in this episode 01:21 Welcome, Andrew Menechian 02:19 From shy kid to bodybuilder and record deadlifter 04:51 Why a goal weight can set you up for disappointment 05:45 What body composition really means 08:06 Why BMI falls short 08:52 Can you build muscle and lose fat at the same time? 11:41 Sponsor: Timeline 12:35 How to avoid losing muscle on a GLP-1 13:12 How much protein you really need 16:53 How much strength training it takes to keep muscle 18:36 Why morning workouts make the habit stick 21:09 Strength training with injuries or physical limitations 23:35 The Plateau Breakthrough Playbook 24:57 Fat loss first or muscle first? 26:56 Metabolic adaptation and reverse dieting 27:24 His diet-break strategy for plateaus 30:33 Where to find Andrew MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail Most people think of a GLP-1 as a weight loss medication, but for your heart, the story starts before the scale moves much at all. Board-certified cardiologist and lipidologist Dr. Sirisha Vadali explains what the research shows about GLP-1s and cardiovascular risk, the simple routine she starts her patients on, and what she monitors along the way. You'll also hear why she doesn't recommend a GLP-1 for family history alone, and about one genetic cholesterol marker that diet and exercise can't change, a lab she says everyone should have checked once in their lifetime. **IN THIS EPISODE** - How GLP-1s went from diabetes drugs to heart protection, with or without diabetes - Why some heart benefit appears before major weight loss, and why no one knows exactly how yet - Who GLP-1s are currently indicated for in cardiovascular risk reduction, and why semaglutide (Wegovy) is the one with outcomes data so far - Why muscle mass, protein, and strength training belong in every GLP-1 plan - Dr. Vadali's simple phase one: 100 grams of protein (30 to 40 grams in the morning), 25 grams of fiber, water, and strength training twice a week at home - Watching blood pressure, heart rate, hydration, and kidney function on a GLP-1 - Fatigue and low motivation after the shot: what to rule out first - Whether family history alone is a reason to start a GLP-1 - The heart labs she checks, including Lp(a), ApoB, hs-CRP, and a coronary calcium score - What Lp(a) is, why it's a one-time lifetime screening, and the treatments expected in the next few years - A word of caution on buying unapproved triple agonists online - Simple longevity habits: sleep, stress, walking after meals, and the 80/20 approach - Why hunger coming back isn't a reason to panic **ABOUT THE GUEST** Dr. Sirisha Vadali, MD, is a board-certified cardiologist and advanced lipidologist specializing in prevention, cardiometabolic medicine, and women's heart health. She is program director for HonorHealth's Cardiometabolic Program in Scottsdale, Arizona, and a member of the HonorHealth Women's Heart Health team. Dr. Vadali focuses on prevention-forward care, using advanced lipid testing, coronary calcium scoring, and lifestyle medicine to help patients lower cardiovascular risk and build sustainable, healthy habits. **CONNECT WITH DR. SIRISHA VADALI** Website: https://www.sirishavadali.com Instagram: https://www.instagram.com/vadalimd/ HonorHealth Cardiometabolic Program: https://www.honorhealth.com/physicians/sirisha-vadali **SPONSORS** This episode is brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours. This episode is also brought to you by Tyde Wellness, the GLP-1 provider Ana uses, with nutrition guidance built for GLP-1s, independent licensed providers, and a care team that answers when something comes up. Go to https://tydewellness.com/GLP1Hub and use code GLP1Hub50 for $50 off your first month. **CHAPTERS** 00:00 Preview: why wait for a heart attack? 00:12 What's in this episode 01:07 Welcome, Dr. Sirisha Vadali 02:11 How GLP-1s went from diabetes drugs to heart protection 03:35 How GLP-1s protect the heart, even before weight loss 05:35 Semaglutide vs. tirzepatide: which she uses and why 06:17 What lower obesity rates could mean for heart health 08:44 Lower BMI and high risk: lifestyle first, then a low dose 10:26 Her simple phase one routine and at-home strength training 13:23 Kidneys, hydration, and how often to check blood pressure 14:33 Fatigue and low motivation after the shot 15:59 Sponsor: Timeline 16:53 Is family history a reason to start a GLP-1? 18:31 The heart lab panel she recommends 20:10 New Lp(a) treatments on the way 21:08 What Lp(a) is and why it matters 23:25 A caution on unapproved triple agonists 26:41 Sponsor: Tyde Wellness 27:42 Longevity basics: sleep, stress, walks, and 80/20 30:29 Quick fixes, food noise, and when hunger comes back 32:09 Where to find Dr. Vadali MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail A daily GLP-1 pill sounds like an easy way to maintain your weight loss, but what happens when it doesn't work like the shot did? Registered dietitian Whitney Black, who lives with type 1 diabetes, shares what happened when she switched from Zepbound to Foundayo (orforglipron) for maintenance, and why she went back after two months. You'll hear how her fullness cues, blood sugar, and insulin needs changed, and what she tells clients about weight regain. The surprise wasn't the food noise. It was a different signal that quietly went missing. This is one person's experience, not a verdict on how the pill will work for everyone. IN THIS EPISODE - Whitney's path to Zepbound with type 1 diabetes, Hashimoto's, and PCOS - Why hunger and fullness dysregulation is biology, not a personal failing - Where GLP-1s stand for type 1 diabetes, and why insulin changes need your care team - What Foundayo is (an oral GLP-1 from Eli Lilly, not tirzepatide) and how its dosing differs - How her fullness cues and blood sugar changed on Foundayo, and the roughly 15 pounds she regained in two months - Cost versus effectiveness when choosing a maintenance option - Switching back to Zepbound and slowly titrating up again - Practical and mental strategies when weight comes back after a break in medication ABOUT THE GUEST Whitney Black, MBA, MS, RD, LD, LMNT, is a registered dietitian specializing in weight management and practical nutrition for individuals using GLP-1 medications. Through her private practice and online education, she helps people navigate nutrition, weight management, and metabolic health with an evidence-based, realistic approach. Whitney also brings her own lived experience with weight management and GLP-1 medications to her work, allowing her to connect clinical expertise with the real-life experience of navigating these treatments. She is also the author of an upcoming GLP-1-focused cookbook with Fair Winds Press. CONNECT WITH WHITNEY BLACK Instagram: https://www.instagram.com/whitney.the.dietitian/ Work with Whitney (Nourish): https://signup.nourish.com/providers/whitney-black SPONSORS This episode is brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours. This episode is also brought to you by Tyde Wellness, the GLP-1 provider Ana uses, with nutrition guidance built for GLP-1s, independent licensed providers, and a care team that answers when something comes up. Go to https://tydewellness.com/GLP1Hub and use code GLP1Hub50 for $50 off your first month. CHAPTERS 00:00 Preview: why the pill appealed to her 00:21 Introduction 01:04 Welcome, Whitney Black 02:17 Life before GLP-1s with type 1 diabetes, Hashimoto's, and PCOS 04:54 Starting Zepbound as a dietitian 06:53 Fullness cues: it's biology, not willpower 08:38 GLP-1s and type 1 diabetes today 12:29 Maintenance, dosing, and why she tried Foundayo 12:57 What Foundayo is (and isn't) 14:29 Sponsor: Timeline 15:23 Foundayo dosing and the first weeks 16:44 Losing the fullness signal 18:53 Rising blood sugar and insulin resistance 19:26 Cost versus effectiveness 21:40 Back on Zepbound 24:00 Advice when weight comes back after a break 26:14 Sponsor: Tyde Wellness 27:14 Why it's not just an appetite suppressant 30:08 Where to find Whitney 31:26 Closing MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail If you're taking a GLP-1, headlines about sudden vision loss can leave you wondering whether the medication helping you lose weight is putting your eyesight at risk. Ana Reisdorf talks with Dr. Luke Sorrell about NAION, a rare optic nerve condition, and the semaglutide research behind those headlines. You'll learn how to put "double the risk" into perspective, what questions to bring to your doctor, and why your health history matters to the conversation. **IN THIS EPISODE** - What NAION is and how it can affect vision - What semaglutide studies suggest, and the limits of observational research - Why relative risk and absolute risk tell different parts of the story - How diabetes, sleep apnea, cardiovascular health, and optic nerve anatomy fit into the discussion - Blood pressure changes, dehydration, and rapid blood sugar changes as possible contributing factors - Questions to ask your prescriber and eye care professional about your individual risk - What remains uncertain about tirzepatide and other GLP-1 medications - Weighing potential eye risks alongside the benefits of GLP-1 treatment **ABOUT THE GUEST** Dr. Luke Sorrell is a board-certified internal medicine physician, Fellow of the American College of Physicians, and founder of Sorrell MD, a concierge longevity and precision telemedicine practice based in Dallas-Fort Worth, Texas, serving patients across the U.S. He trained at UT Houston McGovern Medical School and completed his residency at Baylor University Medical Center in Dallas. His career has spanned hospital medicine, primary care, and longevity medicine. Today, he works with high-performing and health-conscious individuals across the country, using tools like cardiac CT angiography, VO2 max and metabolic testing, DEXA, genomics, and advanced hormone and lipid panels to identify health risks earlier. He also advises health tech companies building the next generation of care. **CONNECT WITH DR. LUKE SORRELL** Website: https://www.sorrell-md.com LinkedIn: https://www.linkedin.com/in/luke-sorrell-md/ Instagram: https://www.instagram.com/sorrellmd/ Facebook: https://www.facebook.com/SorrellMD Substack: https://substack.com/@sorrellmd **SPONSOR** Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month. https://tydewellness.com/GLP1Hub **CHAPTERS** 00:00 GLP-1s and NAION: The "double risk" headline 01:42 Meet Dr. Luke Sorrell 02:52 What is NAION? 05:10 How rare is NAION? 06:13 Diabetes, sleep apnea, and other risk factors 07:50 What the studies show and their limitations 10:49 Relative risk versus absolute risk 11:58 Sponsor: Tyde Wellness 13:22 Semaglutide, tirzepatide, and unanswered questions 14:22 Possible mechanisms: Blood pressure, oxygen, and hydration 19:05 Eye exams, optic nerve anatomy, and rapid A1C changes 22:15 Questions to bring to your doctor 24:54 Ana's Plateau Breakthrough Playbook 26:15 Staying grounded when health headlines spread 27:20 Retatrutide and the future of GLP-1 treatment 29:31 Connect with Dr. Sorrell 30:01 Weighing eye concerns against cardiovascular benefits 31:25 Closing thoughts and podcast reviews MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail If breast cancer runs in your family, you may be wondering whether you're getting the right screening and what else you can do to lower your risk. Ana Reisdorf talks with Dr. Anne Peled about how GLP-1s may shift the balance, what everyday habits you should build, and why weight can become harder to manage during and after treatment. You'll learn which questions to bring to your care team, how to protect your nutrition, and what emerging GLP-1 research still hasn't answered. **IN THIS EPISODE** - How family history and breast density can shape your screening conversation - Exercise, alcohol, and food choices in the discussion about lowering breast cancer risk - Why weight, inflammation, and cancer risk are more complicated than a single cause - What early GLP-1 research suggests, and why prevention questions remain unanswered - Why hormone-blocking medications and other cancer treatments can affect weight - Protecting protein and nutrient intake while coordinating weight management with cancer care - Personalized treatment, emerging research, and advocating for yourself **ABOUT THE GUEST** Dr. Anne Peled is a breast cancer and reconstructive surgeon in San Francisco and a two-time breast cancer survivor. She earned her medical degree at Harvard Medical School and completed plastic and reconstructive surgery training and a breast surgical oncology fellowship at UCSF. She is co-director of the Breast Care Center of Excellence at Sutter Health California Pacific Medical Center. Her work focuses on improving breast surgery and reconstruction outcomes, and she brings both a surgeon's and a patient's perspective to care. **CONNECT WITH DR. ANNE PELED** Website: https://www.annepeledmd.com Instagram: https://www.instagram.com/drannepeled/ **SPONSOR** Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month. https://tydewellness.com/GLP1Hub **CHAPTERS** 00:00 Body fat, estrogen, and breast cancer risk 00:24 Ana's personal connection and the questions this episode explores 01:33 Meet Dr. Anne Peled 03:29 Early detection, family history, and breast density 05:59 Mammograms and questions about additional scans 07:33 Exercise, alcohol, and nutrition 10:05 Weight, inflammation, and emerging GLP-1 research 11:18 GLP-1s for prevention: What we still don't know 13:39 Sponsor: Tyde Wellness 15:05 GLP-1 cancer concerns and unanswered questions 16:30 Why breast cancer treatment can affect weight 18:58 Discussing GLP-1 treatment with your care team 20:12 Protecting nutrition during cancer treatment 22:53 Survivorship and personalized treatment 25:12 Emerging microbiome research 26:44 Beyond the Shot guide 27:46 Genetics and the future of personalized screening 31:03 Self-advocacy, second opinions, and everyday movement 32:46 Connect with Dr. Peled MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail How are GLP-1 type medications and weight control changing the landscape of heart health? If you're using a GLP-1 for weight or blood sugar, which habits and risk factors still deserve attention? Ana Reisdorf talks with Dr. Melanie Icard about stress, sleep, muscle, food choices, and questions to bring to your healthcare team when heart disease runs in the family. Dr. Icard shares how her experience with prediabetes shaped her practice and why she asks patients, "What are you doing to relax?" Ana brings the GLP-1 user's perspective: how to eat well with a smaller appetite and make strength work realistic when life is already full. They also discuss what Ana's family history has prompted her to ask about lab markers and heart imaging. **IN THIS EPISODE** - Why stress and sleep belong in a conversation about heart and metabolic health - What it can look like to make room for real rest during a busy week - How strength work and everyday movement fit into GLP-1 weight loss - Choosing nourishing meals when your appetite is smaller - Questions to ask your clinician about family history, lab markers, and heart imaging - Building habits you can keep up as your health goals change **ABOUT THE GUEST** Dr. Melanie Icard, NMD, is a naturopathic and regenerative medicine physician with 24 years of clinical experience, including 11 years in hospital medicine. She leads Dr. Mel Holistic, a cardiovascular and metabolic medicine practice in Scottsdale and Sedona, Arizona, with a national virtual practice. Her Biohacked Heart Blueprint™ examines how chronic stress and HPA axis dysregulation (changes in the body's stress response) may relate to cardiovascular and metabolic health. She teaches the framework to medical professionals nationally. **CONNECT WITH DR. MELANIE ICARD** Website: https://www.drmelanieicard.com/ Instagram: https://www.instagram.com/drmelholistic/ YouTube: https://www.youtube.com/@Itsdrmel **SPONSORS** Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month. https://tydewellness.com/GLP1Hub **CHAPTERS** 00:00 What are you doing to relax? 00:18 Ana's family history and heart health beyond the scale 01:11 Meet Dr. Melanie Icard 06:23 Family history, calcium scoring, and prevention 07:09 Stress and sleep in the heart health conversation 08:44 Heart imaging and risk questions 12:58 Finding time to truly relax 15:42 Sponsor: Tyde Wellness 17:19 Stress, blood sugar, and GLP-1 goals 20:41 Meal habits and nutrient dense choices 23:54 Lab markers, imaging, and family risk 26:53 GLP-1s and preserving muscle 28:09 Making relaxation realistic 29:23 Beyond the Shot guide 30:24 Workload, boundaries, and healthy habits 32:10 Who Dr. Icard works with 33:42 Connect with Dr. Icard MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail If you're taking a GLP-1, you've probably heard plenty about protein and strength training. Where does creatine fit, and what does it mean if the scale rises after you start taking it? Ana Reisdorf talks with Kristin Kirkpatrick about muscle health, the practical choices involved in taking creatine, and what the research can and cannot yet tell us about benefits beyond the gym. Kristin explains how creatine works alongside resistance training, why a loading phase may not be necessary, and what to consider when choosing a form. She and Ana also discuss bloating, water retention, early research on brain health, and whether you can build muscle after starting a GLP-1. **IN THIS EPISODE** - What creatine does in the body and why it comes up in the muscle-health conversation - How creatine, protein, and resistance training fit together during GLP-1 weight loss - What emerging research suggests about brain health and what it does not establish - Creatine monohydrate, HCl, powders, and gummies: questions to consider when choosing a product - Loading phases, dose, and timing, and why individual needs vary - Water retention, bloating, and why a change on the scale may not mean fat gain - Building strength and muscle after starting a GLP-1 **ABOUT THE GUEST** Kristin Kirkpatrick, MS, RD, is a registered dietitian at Cleveland Clinic and president of KAK Consulting, LLC. She has worked in nutrition and integrative care for more than 20 years, contributes to TODAY.com, and co-authored Skinny Liver and Regenerative Health with gastroenterologist Ibrahim Hanouneh, MD. **CONNECT WITH KRISTIN** Website: https://www.kristinkirkpatrick.com/ Instagram: https://www.instagram.com/fuelwellwithkrissy/ **SPONSOR** Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month. https://tydewellness.com/GLP1Hub Velogenix's Project Aeterna offers a free at-home mobility baseline and Pro assessments of strength, balance, and gait. Use code OFF for $50 off your first year of Pro. https://velogenix.com **CHAPTERS** 00:00 Why creatine is getting attention beyond the gym 01:30 Meet Kristin Kirkpatrick 03:22 Kristin's approach to integrative nutrition 06:09 What creatine does in the body 08:05 Creatine myths: Is it just for bodybuilders? 09:09 What the brain-health research can and cannot tell us 12:03 Creatine, strength training, and GLP-1 muscle health 15:13 Sponsor: Tyde Wellness 16:39 Monohydrate vs. HCl, dose, and timing 19:29 Gummies, powder, and the coffee question 23:24 Water retention, side effects, and the scale 26:07 Do you need a loading phase? 28:11 Sponsor: Velogenix 29:14 Muscle, mobility, and healthy aging 31:55 Can you build muscle after starting a GLP-1? 32:58 Connect with Kristin MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail What can getting out of a chair tell you about your muscle health? Ana Reisdorf, Registered Dietitian and GLP-1 user, joins muscle and bone researcher Mark Hamrick to explore staying strong during GLP-1 weight loss, perimenopause, and menopause. You'll learn what three simple assessments can reveal about physical function, and why muscle size alone doesn't tell the whole story. Mark explains the differences between muscle mass, quality, strength, and power, and how they connect to everyday movement and healthy aging. Ana shares her own assessment results and asks whether her regular exercise routine is enough. They also discuss bone density, fall risk, and finding an approach to exercise that works when pain or physical limitations get in the way. **IN THIS EPISODE** - Why losing muscle size doesn't necessarily mean losing the same amount of strength - What chair rises, single-leg balance, and walking speed can tell you about physical function - How menopause, sleep, and activity levels enter the muscle-health conversation - Resistance training, protein, and the research Mark discusses on creatine - Adapting exercise with help from a physical therapist when movement is painful - Bone density, DEXA scans, fall risk, and questions to bring to your healthcare provider **ABOUT THE GUEST** Mark Hamrick is president and co-founder of Velogenix and a former Regents Professor at the Medical College of Georgia. His research on muscle and bone aging has received NIH funding over the last two decades. He has published more than 225 peer-reviewed papers and advised NASA on muscle and bone loss in space. At Velogenix, he is applying that experience to tools for quickly assessing muscle health at home. **CONNECT WITH MARK** Website: https://velogenix.com LinkedIn: https://www.linkedin.com/in/mark-hamrick-44b287121/ **SPONSORS** Velogenix, co-founded by our guest, Mark Hamrick. Project Aeterna offers at-home assessments of strength, balance, and walking speed. Try the free baseline test, or use code OFF for $50 off your first year of Pro. https://velogenix.com Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month. https://tydewellness.com/GLP1Hub **CHAPTERS** 00:00 Why muscle and bone health deserve attention 01:27 Meet Mark Hamrick 02:39 Three simple assessments of physical function 05:11 Muscle size, quality, and the menopause transition 09:59 The connection between muscle and longevity 12:21 Walking, strength training, and protein 13:57 Everyday signs your strength may be changing 15:08 Sponsor: Tyde Wellness 16:33 What to do with your assessment results 17:48 Exercising with pain or physical limitations 19:13 Ana's results: Is regular exercise enough? 22:22 Sitting, standing, and moving more 24:08 Bone density, DEXA scans, and fall risk 28:46 Beyond the Shot guide 29:47 Mark's three takeaways for muscle and bone health 34:19 Try Project Aeterna and connect with Mark MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail You've reached your goal weight on a GLP-1. Now what: stay on it, lower the dose, or take a break? Ana Reisdorf, Registered Dietitian and GLP-1 user, joins pharmacist Dr. Stephanie Redmond to explore microdosing, cycling on and off medication, and the questions coming up around perimenopause and menopause. You'll hear where clinical experience meets unanswered questions—and why a smaller dose can still bring surprises. Stephanie shares her own experience with low-dose side effects and returning hunger. Together, they discuss concerns about weight regain and muscle loss, telehealth screening, and why your long-term plan deserves as much attention as getting started. **IN THIS EPISODE** - What people mean by GLP-1 "microdosing" and why the term can be confusing - Emerging uses beyond weight loss and diabetes, and where evidence is still limited - Stephanie's experience with constipation, bloating, and returning hunger - Questions about cycling, stopping treatment, and maintaining weight loss - Perimenopause, menopause, insulin resistance, and individualized care - The role of muscle preservation, nutrition, movement, and ongoing clinical support **ABOUT THE GUEST** Dr. Stephanie Redmond, PharmD, CDE, BC-ADM, is a pharmacist specializing in hormone health and diabetes management. She founded the Medication Therapy Management practice at Ridgeview Clinic System in Minnesota and has educated clinicians nationally on GLP-1 therapies. She is also the founder of Dr. Stephanie's®, a clinician-led supplement brand focused on GLP-1 support, hormone health, and women's wellness. **CONNECT WITH STEPHANIE** Website: https://drstephanies.com Instagram: https://www.instagram.com/drstephanies YouTube: https://www.youtube.com/@drstephanies **SPONSORS** Svalto Cooler Pro is a portable, battery-powered cooler for refrigerated medication. Use code GLP1HUB for 15% off. https://svalto.com Velogenix's Project Aeterna offers at-home assessments of strength, balance, and mobility. Take the free baseline test, or use code OFF for $50 off your first year of Pro. https://velogenix.com **CHAPTERS** 00:00 GLP-1 maintenance: What happens next? 01:34 Meet Dr. Stephanie Redmond 04:08 Emerging uses and gaps in the evidence 07:46 What does "microdosing" actually mean? 11:08 Telehealth screening and questions about inflammation 14:24 Sponsor: Svalto 15:20 Weighing the risks of low-dose use 17:05 Stephanie's personal experience with side effects 18:43 Cycling, returning hunger, and weight regain 22:39 GLP-1s, perimenopause, and menopause 26:59 Sponsor: Velogenix 27:58 The future of GLP-1 use and long-term planning 32:24 Connect with Dr. Stephanie Redmond 34:19 Stay connected with GLP-1 Hub MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail You can feel good about your GLP-1 weight loss and still wonder why your face looks different. Ana Reisdorf, Registered Dietitian and GLP-1 user, talks with wound-healing scientist Brian Pilcher, PhD, about what people call "Ozempic face," how volume loss differs from loose skin, and the treatment options available today. Could future treatments help the body rebuild some of its own tissue? Brian explains the science behind tissue regeneration and what his company, Conexeu Sciences, is studying. Its technology remains preclinical, with safety and effectiveness still to be established in human trials. **IN THIS EPISODE** - How weight loss can change facial volume and skin support - The differences between fillers, biostimulators, and skin-tightening treatments - Why tissue regeneration involves cells, biological signals, and a supporting framework - What early research can tell us, and what still needs to be tested in people - Why wound-care development and potential aesthetic applications have different timelines - Unanswered questions about GLP-1s and skin, plus caution around exosome claims **ABOUT THE GUEST** Brian Pilcher, PhD, is a wound-healing biologist and Chief Medical Officer of Conexeu Sciences. He brings more than 25 years of experience in dermatology and aesthetics, including leadership roles at BioForm Medical, Merz North America, and Suneva Medical. He holds a doctorate in cell and molecular biology from the University of Oklahoma College of Medicine. His research career included postdoctoral work at Washington University in St. Louis and a faculty position studying wound repair at UT Southwestern Medical Center. Today, his work focuses on translating tissue-repair science into the development of medical devices and potential regenerative treatments. **CONNECT WITH BRIAN** Conexeu Sciences: https://www.conexeu.com/ **SPONSORS** Tyde Wellness offers clinician-guided GLP-1 care and ongoing support. Get $50 off your first month with code GLP1Hub50. https://tydewellness.com/GLP1Hub Calocurb is an appetite-support supplement made with Amarasate hops extract. Use code ANA10 for 10% off. https://www.calocurb.com/ **CHAPTERS** 00:00 Facial changes after GLP-1 weight loss 05:23 What people mean by "Ozempic face" 08:58 What tissue regeneration actually means 13:51 Sponsor: Tyde Wellness 15:17 Targeting different tissues 16:27 Fillers, biostimulators, and skin tightening 21:27 What researchers still need to prove about safety 22:52 Human studies and the development timeline 26:32 Combining treatments and deciding when to start 28:23 Sponsor: Calocurb 29:22 Unanswered questions about GLP-1s and skin 30:45 Future research and caution around exosomes 33:42 Where to learn more and breast-tissue research 35:05 Stay connected with GLP-1 Hub MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail Your appetite is smaller on a GLP-1, but how do you know whether those few bites are giving you what you need? US Dietitian Ana Reisdorf and UK Nutritionist Rob Hobson explore how to put together balanced meals, make room for protein and fiber, and eat regularly without returning to calorie counting. They also unpack why familiar diet rules can make nourishing yourself harder when you’re already eating less. **IN THIS EPISODE** - What “every bite counts” means when your appetite and portions shrink - Moving beyond calorie counting and fear of carbohydrates or healthy fats - Finding a regular eating pattern that works with a low appetite - Rob’s “rule of four” for building meals with protein, produce, a fiber-rich carbohydrate, and healthy fat - Using convenient foods like precooked chicken, canned beans, and frozen vegetables - Looking beyond high-protein labels and understanding where protein shakes can fit - Understanding lean mass versus muscle loss and the role of resistance exercise - Adding fiber gradually, staying hydrated, and taking a food-first approach to supplements **ABOUT THE GUEST** Rob Hobson is an award-winning Registered Nutritionist and Sunday Times bestselling author with over 20 years of experience in public health and sports nutrition. His latest book, Every Bite Counts, explores how to maximize nutrition when appetite is reduced, including during GLP-1 treatment. His practical approach focuses on building nutrient-dense meals that support muscle, energy, long-term health, and sustainable eating habits. **CONNECT WITH ROB** Instagram: https://www.instagram.com/robhobsonnutritionist YouTube: https://www.youtube.com/@robhobsonnutritionist Website: https://robhobson.co.uk Every Bite Counts: https://theexperimentpublishing.com/catalogs/summer-2026/every-bite-counts/ **SPONSORS** This episode is supported by Svalto and CaloCurb. Svalto: Learn more about the Svalto Cooler Pro, the portable medication cooler for traveling with your GLP-1 or peptides medications, at https://svalto.com. Use code GLP1HUB for 15% off. CaloCurb: Learn more about the plant-based supplement featured in this episode’s sponsor message at https://calocurb.com. Use code ANA10 for 10% off. Discuss supplement use with your healthcare provider. **CHAPTERS** 00:00 Making every bite count with a smaller appetite 04:42 Nutrient density and moving beyond calorie counting 09:23 Eating regularly when you’re not hungry 12:55 Sponsor: Svalto 13:47 Building balanced meals with the rule of four 16:10 Convenience foods that make meals easier 18:31 Protein-added foods and when shakes can help 20:40 Protein, muscle, and resistance exercise 24:45 Sponsor: CaloCurb 25:45 Fiber, hydration, and starting small 27:37 A food-first approach to supplements 29:29 Building habits without chasing perfection 31:00 Where to find Rob and Every Bite Counts MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail Poor sleep, mood changes, low energy, and new weight around the midsection can be easy to blame on aging or GLP-1 treatment alone. In this episode, Ana Reisdorf and Sharon Lemoine explore how hormone changes, thyroid function, insulin resistance, muscle loss, and lifestyle can overlap, and what a more complete evaluation may include. You’ll learn what to look for in a hormone-informed provider, why protein and muscle monitoring matter when using a GLP-1, and why a “normal” test result may not tell the whole story. **IN THIS EPISODE** - Sharon’s experience with type 1 diabetes, surgical menopause, Graves’ disease, and thyroid cancer - What hormones do and why hormone-related symptoms can be difficult to recognize - Common signs of changing estrogen, progesterone, and testosterone levels - Why patients may still feel something is wrong after being told their results are normal - Questions to discuss with a provider when considering hormone testing or therapy - How menopause, muscle loss, and insulin resistance may contribute to changes in body composition - Why protein, resistance training, and body-composition monitoring matter during GLP-1 treatment - How Sharon decides when a GLP-1 may fit into a broader health plan - Hormone-related symptoms and low testosterone in men - How to find a qualified provider who listens and evaluates the complete picture - Why hormone therapy requires an individualized discussion of potential risks and benefits **SPONSORS** CaloCurb: https://calocurb.com Use code ANA10 for 10% off. Tyde Wellness: https://tydewellness.com/GLP1Hub Use code GLP1Hub50 for $50 off your first month. **ABOUT THE GUEST** Sharon Lemoine, MSN, ARNP, is a Nurse Practitioner, entrepreneur, public speaker, and advocate for a new model of healthcare that integrates faith, science, and personal responsibility. With more than 25 years of experience in emergency medicine and over 30 years in healthcare, Sharon has dedicated her career to helping patients move beyond symptom management and reclaim ownership of their health through hormone optimization, functional medicine, preventative care, and faith-based wellness principles. **CONNECT WITH SHARON** Website: https://gigharbormedicalspa.com/ YouTube: https://www.youtube.com/@SharonLemoine-ARNP **CHAPTERS** 00:00 When Hormonal Symptoms Feel Overwhelming 00:26 What This Episode Covers 01:42 Meet Sharon Lemoine 02:42 Type 1 Diabetes, Surgical Menopause, and Thyroid Disease 07:13 What Hormones Do 08:29 Signs Your Hormones May Be Involved 10:57 Common Perimenopause and Menopause Symptoms 12:49 How Long Does Hormone Therapy Continue? 15:37 Sponsor: CaloCurb 16:36 Life After the Menopause Transition 17:35 Midsection Weight Gain, Hormones, and GLP-1s 20:41 Lifestyle and When a GLP-1 May Fit 22:04 Finding the Right Hormone Provider 23:05 Hormone Panels and Other Lab Tests 24:50 Hormone Concerns in Men 26:48 Sponsor: Tyde Wellness 28:13 Low Testosterone in Younger Adults 30:36 The Future of Hormone Health and Peptides 31:31 Hormone-Therapy Fears and Individual Risk 33:17 Connect With Sharon MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.