Advertise on podcast: The Tell-Tale Heart: The Pharmacist's Cardiovascular Digest

This was a collaboration with the National Lipid Association's Lipid Insights podcast. You can listen to more Lipid Insights on Apple Podcasts or Spotify. Michael J. Wilkinson, MD, FACC, FNLA, is an associate professor of medicine and director of the advanced lipid treatment program at UC San Diego Health. You can find him on Linkedin.

Dr. Morris and Dr. Beavers discuss the 2026 American College of Cardiology (ACC) expert consensus decision pathway for heart failure with preserved ejection fraction (HFpEF), published in the Journal of the American College of Cardiology. You can read the report here. About the Guest  Alanna Morris, MD, MSc, is a heart failure cardiologist and the Executive Medical Director, US Medical Affairs at Bayer.  Upcoming Meeting  The Heart Failure Society of America Annual Scientific Meeting 2026 takes place October 9–12, 2026, in Phoenix, Arizona.

Trials Discussed:STAREE (NCT02099123)REACT (NCT06692127)AMUNDSEN (NCT04951856)ENRICH-AF (NCT03950076)LIBREXIA-ACS (NCT05754957)PREMIUM (NCT05709626)SWITCH SWEDEHEART (NCT05183178) EMAIL-HF (NCT05890131)ADHERE-ASCVD (NCT07522645)TIME-HF  (CTRI/2021/11/037797)H-HeFT & Met-HeFT  (DANHEART, NCT03514108)ACASA-TAVI (NCT05035277)

CARDIO-TTRansform — eplontersen in transthyretin amyloid cardiomyopathy (ATTR-CM). ClinicalTrials.gov: NCT04136171 SINGLE-AF — direct oral anticoagulation in patients with atrial fibrillation at intermediate stroke risk. ClinicalTrials.gov: NCT04437654 POET II — response-tailored, shortened antibiotic therapy in left-sided infective endocarditis. ClinicalTrials.gov: NCT03851575

Management of Heart Failure With Preserved Ejection Fraction: 2026 ACC Expert Consensus Decision Pathway: A Report of the American College of Cardiology Solution Set Oversight Committee

Learn more about the AHA scientific statement here.

In this episode of The Tell-Tale Heart, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, welcomes back Lavinia Salama, PharmD, BCACP, BCGP, BC-ADM, CDCES, for an in-depth look at the new cardiovascular-kidney-metabolic (CKM) guidelines and how they translate into everyday practice. Salama says she's encouraged that CKM recommendations have evolved from a conceptual framework into a formal, multisociety guideline, with new emphasis on albuminuria, the PREVENT risk equation, and routine screening for obstructive sleep apnea, MASLD/MASH, and social determinants of health.

In this solo episode of the Tell-Tale Heart podcast, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, delivers an immediate reaction to the newly released 2026 AHA/ACC/ADA/ASN guidelines for cardiovascular kidney metabolic (CKM) syndrome. Beavers calls the document a landmark framework that formally unites obesity, diabetes, chronic kidney disease, heart failure, and atherosclerotic cardiovascular disease into a single disease continuum — a shift he argues changes everything about how clinicians should approach prevention.

In this mini news episode of the Tell-Tale Heart podcast, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, highlights three major developments in cardiovascular and cardiometabolic medicine that pharmacists should have on their radar.

In this episode of The Tell-Tale Heart, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, speaks with Rhonda Monroe, MBA, a heart failure survivor and lead advocate at HeartLife, about her lived experience with spontaneous coronary artery dissection (SCAD) and the systemic failures that nearly cost her life. Following the birth of her third child, Monroe experienced classic cardiac symptoms but was repeatedly misdiagnosed as having indigestion or "hysterical motherhood" despite an EKG confirming an acute myocardial infarction.

SPIRIT-HF  CHAMPION-AF  SMART-DECISION  VESALIUS-CV (sub-study)  CORAL REEF  Ez-PAVE

You can learn more about the 2026 dyslipidemia guidelines here: 2026 Dyslipidemia Guideline Hub | JACC

You can reach the guests on this episode here: Kristen Campbell, PharmD

Learn more about the HI-PEITHO trial here.You can reach the guest on this episode here:Allison Burnett, PharmD, PhC, CACP, on LinkedIn

Learn more about the OCEANIC-STROKE trial here.