Advertise on podcast: from Dreamers to Disruptors

As we enter the new year, the mandate is clear: evolve clinical research or get left behind. Join us to revisit conversations between Medidata CEO Anthony Costello and some of the leading industry minds—including Every Cure's David Fajgenbaum, Digital Medicine Society's Jennifer Goldsack, and Click Therapeutics' David Klein—as they look to the future of life sciences in 2026 and beyond. From unlocking deeper data insights to scaling radical innovation, our guests issue a direct call to action: harness today's cutting-edge technology to build a faster, smarter, and healthier world for patients everywhere. Visit our website Read our blog Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn

David Fajgenbaum's relationship to drug repurposing is personal, professional, and one of the most inspiring stories in modern medicine. Diagnosed with Castleman disease and running out of treatment options, David used his research skills to identify an existing drug that saved his life. Join David and Medidata CEO Anthony Costello to explore the origins of Every Cure—and how David's experience became the seed for a nonprofit that uncovers life-changing uses for treatments already approved for other conditions. Discover Every Cure's innovative approaches to data, the scope of unmet needs across healthcare, and how pharmaceutical companies can contribute to a future where we unlock the full potential of treatments for all. Visit our website Read our blog Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn Follow David: LinkedIn

Jennifer Goldsack has made it her mission to push the boundaries of how technology can enhance healthcare. As founder and CEO of the Digital Medicine Society (DiMe), she supports digital innovators exploring new ways to deliver better outcomes for patients everywhere. Jennifer and Medidata CEO Anthony Costello explore how clinical trials once led the way in life sciences digitization, why they're falling behind, and how we can get our industry back on track. Join them to discover how Jennifer is promoting innovation and making smarter use of clinical data, as well as her personal story of navigating the healthcare system and confronting the everyday challenges patients face. Visit our website Read our blog Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn Follow Jennifer: LinkedIn

Patient-centric trials are essential for the future of clinical development, but there are hurdles to overcome. The industry must adapt to the needs and preferences of patients, incorporate high-quality data, and embrace innovative technology so patients and trials can thrive together. IQVIA is leading the healthcare industry with its unparalleled management of clinical data. SVP, Data Sciences, Safety and Medical Writing Tracy Mayer sits down with Medidata CEO Anthony Costello to explore the growth of patient-centric trials and the adoption of AI that have made this growth possible. Join Tracy and Anthony to discover the future of data management and how it will improve data acquisition and accelerate data delivery, ultimately easing the stress of patient journeys. Visit our website Read our blog Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn Follow Tracy: LinkedIn

Digital therapeutics are poised to transform healthcare as we know it, delivering Software-Enhanced Drugs™ to patients that extend and expand on traditional treatments, as well as valuable data and new commercial opportunities to pharmaceutical companies. Click Therapeutics is a leading light in prescription digital therapeutics, and CEO David Benshoof Klein's insights into their design and implementation are second to none. He joins Medidata Solutions' CEO Anthony Costello to explore the growth of evidence-based, Software-Enhanced Drugs™ and the art of creating effective technologies that change lives. Join David and Anthony to explore the vast potential of digital therapeutics for treating everything from migraines to cancer, and how to build solutions that genuinely benefit patients. They discuss the new Regulatory Considerations for Prescription Drug Use-Related Software (PDURS), and what new legislation means for the growth of software-based treatment adoption around the world. Visit our website Read our blog Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn Follow David: LinkedIn

When it comes to understanding the application and potential of AI in clinical trials, you're unlikely to find a greater expert than Arnaub Chatterjee, Datavant's GM and president, life sciences, ecosystem and public sector. Arnaub has experience working for private companies, the US government, and as a teacher at Harvard Medical School, giving him unparalleled insight into the AI technologies reshaping study design and helping us to draw valuable insights from the vast amounts of data captured by healthcare organizations. Join Arnaub and Medidata CEO Anthony Costello as they take a deep dive into the cutting-edge of clinical data management. They explore Arnaub's pioneering work in the early days of Medidata's adoption of AI, how we can ensure that our models are reliable and unbiased, and our collective project to build an environment that leverages patient data between and beyond clinical trials. Visit our website Read our blog Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn Follow Arnaub: LinkedIn

Marisa Co has built a career based on intimate knowledge of every aspect of the pharmaceutical industry, giving her unparalleled insight into clinical trials and how to drive change in life sciences. Alongside senior roles at some of the biggest names in healthcare, her participation in the launch of Mytrus paved the way for decentralized clinical trials (DCTs). Join Marisa and Medidata CEO Anthony Costello as they dive into the technologies that enable DCTs to give patients ownership of their clinical trial journeys, and the AI boom that is transforming every aspect of clinical research. Marisa shares her unique insights into overcoming risk aversion within the clinical trials industry, and ensuring the successful adoption of game-changing technologies. She and Anthony dig into the progress of incorporating AI and eConsent into studies, and how to successfully deliver transformative change in healthcare.   Visit our website Read our blog Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn Follow Marisa: LinkedIn

As life expectancy increases and survival rates for cancer and heart disease improve, central nervous system (CNS) conditions are increasingly becoming a focus in healthcare. The search to treat Alzheimer's disease and other forms of dementia grows every day as more people feel their impact. Cogstate CEO Brad O'Connor has over 20 years of experience driving his company to expand our collective knowledge and ability to detect CNS diseases as we work towards a cure for dementia. He and Medidata CEO Anthony Costello explore this critical and challenging area of clinical research, plus the strides being made to advance it. Brad shares Cogstate's work to develop new treatments and reliable, universal tests for assessing changes in cognition. From blood-based biomarkers to AI-powered clinical trials, Brad and Anthony outline a future for people with Alzheimer's where earlier identification of risk factors leads to longer, happier lives for patients and loved ones.    Visit our website: www.medidata.com Read our blog: Clinical Minds Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Cogstate: LinkedIn, Instagram, X Follow Anthony: LinkedIn Follow Brad: LinkedIn

As Bayer's first Chief Digital Officer, Jessica Federer is a true pioneer in life sciences. An early driver of digital transformation in clinical research and a champion for women's health, she has a unique grasp on the challenges we face, and the opportunities waiting to be realized. Listen as Medidata CEO Anthony Costello sits down with Jessica to explore her exceptional career, from her work to uplift women's voices in the industry and tackle gender-based inequalities in healthcare, to the potential of AI, digital therapeutics, and other emerging technologies. Jessica shares her insights into the shocking underrepresentation of women in clinical trials, and why their inclusion is essential for our understanding of conditions including autoimmune diseases and Alzheimer's. She and Anthony explore roadblocks to digital adoption in clinical trials, and how pharma companies can promote innovative treatments like precision medicine to transform patient experiences and outcomes.   Visit our website: www.medidata.com Read our blog: Clinical Minds Follow Medidata: LinkedIn, Instagram, X, YouTube Follow Anthony: LinkedIn Follow Jessica: LinkedIn, Instagram, X, Bluesky