As a double board-certified OB-GYN and reproductive endocrinologist, I’ve dedicated my career to helping individuals navigate their reproductive health. However, my passion for this podcast stems not just from my professional background, but from my own fertility journey—giving me a firsthand understanding of the emotional and physical challenges that come with trying to conceive. Through this platform, I will break down the science of fertility in an approachable way, share real patient stories, and explore the latest innovations in reproductive medicine. My goal is to provide compassionate, evidence-based guidance that empowers listeners to make informed decisions about their fertility and future.
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Check latest episodes from Trying to Conceive with Dr. Sasha Hakman podcast
Which IVF Add-Ons Actually Work? PRP, Growth Hormone, Intralipids & More
2026/10/21
Are IVF add-ons actually improving your chances of having a baby, or are you spending thousands of dollars on treatments that haven't been proven to work? In this solo episode, Dr. Sasha breaks down the science behind some of the most commonly offered IVF add-ons, from growth hormone and ovarian PRP to embryo transfer medications and endometrial receptivity testing. Using the latest research, clinical trials, and her own experience as both a reproductive endocrinologist and IVF patient, she explains which treatments may benefit specific patients, which lack convincing evidence, and why live birth rates, not just egg counts or positive pregnancy tests, should be the ultimate measure of success. Whether you're preparing for your first IVF cycle or navigating repeated failed treatments, this episode will help you better understand your options and have informed conversations with your fertility doctor.
In this episode, we cover:
→ IVF add-ons explained: Why additional treatments aren't always better, how to evaluate the research behind them, and the difference between improving egg retrieval, fertilization, pregnancy, and live birth rates
→ Growth hormone during ovarian stimulation: How it works alongside FSH and LH, why it's sometimes used for diminished ovarian reserve (DOR) or poor ovarian response, and what the research actually shows about egg quality, embryo development, and live births
→ Rapamycin for ovarian aging: The emerging research on ovarian reserve, cellular aging, and the mTOR pathway, including why this treatment remains experimental despite promising preliminary findings
→ Ovarian PRP and ovarian rejuvenation: How platelet-rich plasma injections are intended to stimulate ovarian follicles, what the PROVA randomized controlled trial found, and why Dr. Sasha questions the cost and effectiveness of this procedure
→ Calcium ionophore and fertilization failure: How assisted oocyte activation works with ICSI, and why it may improve outcomes in cases of severe male factor infertility, previous poor fertilization, or globozoospermia
→ PICSI vs. ICSI: How hyaluronic acid binding is used to select sperm, the potential impact on miscarriage rates, and why PICSI hasn't consistently demonstrated improved live birth rates
→ Recurrent implantation failure: Why failed embryo transfers don't necessarily mean there's a problem with the uterus, and the role of embryo quality, chromosomal abnormalities, adenomyosis, fibroids, polyps, and uterine scar tissue
→ Intrauterine hCG wash and Neupogen (G-CSF): The theories behind improving endometrial receptivity, implantation, and thin uterine lining, and why evidence for improved live birth rates remains limited
→ Uterine PRP for thin endometrial lining: How platelet-rich plasma may support endometrial growth and implantation, why some studies are promising, and the limitations of the available evidence
→ IV intralipids and reproductive immunology: The theory behind suppressing natural killer cell activity, why intralipid infusions are offered for recurrent implantation failure, and Dr. Sasha's personal experience using them during her own IVF pregnancy
→ Corticosteroids and low-dose aspirin: When steroids are medically indicated, including Dr. Sasha's experience with partial 21-hydroxylase deficiency, and why baby aspirin may help prevent preeclampsia without necessarily improving embryo transfer success
→ Antihistamine protocols: Why some fertility clinics prescribe Claritin, Pepcid, and steroids as part of a "kitchen sink" protocol, and what the research shows about implantation and pregnancy outcomes
→ ERA, EMMA, and ALICE testing: Whether endometrial receptivity testing, microbiome analysis, and endometrial biopsies improve IVF outcomes, and why personalized embryo transfer timing hasn't consistently demonstrated a benefit
→ How to make informed IVF decisions: Understanding randomized controlled trials, meta-analyses, Cochrane reviews, experimental treatments, and why an add-on that helps a specific subgroup of patients may not benefit everyone
Additional episodes mentioned:
→ IVF Medication Protocols: Understanding stimulation protocols, including options for diminished ovarian reserve
→ Embryo Genetic Testing: Exploring the limitations of traditional preimplantation genetic testing and emerging approaches to embryo analysis
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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Postpartum Depression, Anxiety & Psychosis Explained: What Every Woman Should Know
2026/10/14
Mental health during infertility, pregnancy, and postpartum is often misunderstood, and knowing what's normal, what's not, and when to seek help can make all the difference. In this educational episode, Dr. Sasha sits down with Dr. Kristin Lassiter, a board-certified psychiatrist specializing in reproductive psychiatry, to break down the mental health conditions women may experience throughout their reproductive years. Together, they explain the differences between anxiety, depression, OCD, postpartum baby blues, and postpartum psychosis, while addressing common misconceptions about intrusive thoughts and psychiatric medications during pregnancy. From understanding the safety of antidepressants and ADHD medications to recognizing warning signs and knowing where to turn for help, this conversation is designed to give women and their families the knowledge to make informed decisions and advocate for appropriate care.
Mental health resources mentioned in this episode:
Postpartum Support International: postpartum.net
National Maternal Mental Health Hotline: Call or text 1-833-TLC-MAMA (1-833-852-6262) for free, confidential support, available 24/7.
If you or someone you love is experiencing symptoms of postpartum psychosis or an immediate risk of harm, seek emergency medical care.
Medication decisions during pregnancy should always be made with your treating healthcare professional. Do not stop or change prescribed psychiatric medications without medical guidance.
Follow Dr. Kristin Lassiter!
Instagram: @the.reproductive.psychiatrist
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
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How to Make a Birth Plan: Induction, Epidurals, VBAC & Labor Explained
2026/10/07
A birth plan can help you feel prepared for labor, but birth does not always go according to plan. In this solo episode, Dr. Sasha Hakman shares her perspective as both a board-certified OB-GYN and a mom preparing for her third delivery after IVF. She breaks down birth plans, hospital vs. home birth, induction at 39 weeks, VBAC and TOLAC, epidurals, doulas, delayed cord clamping, cord blood banking, and the interventions that may come up during labor. Most importantly, she explains why informed decision-making, flexibility, and finding a care team you trust matter more than creating the "perfect" birth experience.
In this episode, we cover:
→ How to create a realistic birth plan, why Dr. Sasha prefers a one-page list of preferences, and why shared decision-making and informed consent should be at the center of your delivery experience
→ The different approaches to birth, including low-intervention and unmedicated labor, epidural-focused plans, planned induction, scheduled C-section, and TOLAC (trial of labor after cesarean) with the goal of a VBAC
→ Home birth vs. hospital birth, the risks Dr. Sasha considers when choosing where to deliver, who should not consider a home birth, and why she personally prioritizes delivering at a hospital with a high-level NICU
→ Dr. Sasha's first two birth stories, including her scheduled C-section for a breech baby, her unexpectedly fast TOLAC and vaginal delivery, and what those experiences have changed about her birth plan for baby number three
→ 39-week induction vs. waiting for spontaneous labor, what the ARRIVE trial found about elective induction, and why Dr. Sasha personally hopes to deliver by 39 weeks
→ How an induction of labor actually works, including cervical ripening, Foley balloons, Pitocin (oxytocin), medication options, membrane sweeps, dates, nipple stimulation, and why some induction medications are not appropriate after a previous C-section
→ Low-intervention labor, when to go to the hospital, why active labor is now generally considered around 6 centimeters, intermittent vs. continuous fetal monitoring, eating and drinking during labor, and choosing the position that feels best for you
→ Why Dr. Sasha has changed her perspective on doulas, how the right doula can provide continuous support and advocacy, and why your partner may need support during labor too
→ Epidurals and pain management, including the benefits and risks of epidural anesthesia, whether epidurals increase C-section risk, IV pain medication, spinal headaches, blood pressure changes, and why Dr. Sasha plans to request an epidural early this time
→ What happens during pushing and delivery, including tearing vs. episiotomy, vacuum and forceps-assisted delivery, and when interventions may help avoid an emergency C-section
→ What happens immediately after birth, including skin-to-skin, delayed cord clamping for 30 to 60 seconds, placenta delivery, postpartum Pitocin, breastfeeding, and monitoring for postpartum hemorrhage
→ Cord blood banking vs. donation, why Dr. Sasha does not personally plan to use private cord blood banking, and why she prefers donating cord blood to a public bank when possible
→ Dr. Sasha's birth plan for baby number three: spontaneous labor if possible, delivery by 39 weeks, early pain control, continuous fetal monitoring, openness to intervention when medically necessary, and ultimately one priority, a healthy mom and healthy baby
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
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Dr. Mona Amin on Sleep Training, Co-Sleeping & Gentle Parenting (Part 2)
2026/09/30
What does it actually take to raise emotionally resilient kids without losing yourself in the process?
In Part 2 of my conversation with pediatrician and PedsDocTalk founder Dr. Mona Amin, we move from her personal journey into some of the most debated topics in modern parenting: sleep training, co-sleeping, gentle parenting, attachment, boundaries, emotional regulation, and the pressure to get everything "right."
Dr. Mona explains why parenting is rarely as black and white as social media makes it seem. We talk about what the research actually says about sleep training and attachment, why parental sleep matters too, and how families can think about co-sleeping through the lens of risk reduction rather than judgment.
We also unpack the difference between gentle, permissive, authoritative, and authoritarian parenting. Dr. Mona shares why validation alone isn't always enough, why some children actually become more dysregulated when parents over-explain their emotions, and how loving limits can give children both the connection and boundaries they need.
Plus, we get into tantrums, hitting, whining, yelling, parental guilt, repairing after you lose your cool, and why modeling emotional regulation may be one of the most powerful tools we have as parents.
This conversation is such an important reminder that no parent is going to get every moment right. What matters is building a relationship where your child knows they are loved, their emotions are safe with you, and they can always come back to you.
In this episode
→ How Dr. Mona's own birth trauma changed the way she communicates medical and parenting information
→ What the research says about sleep training, attachment, and the Ferber method
→ Why there is no one-size-fits-all approach to infant and toddler sleep
→ Co-sleeping, bed sharing, safe sleep, SIDS risk, and the importance of risk reduction
→ Why a child's temperament and "cuddle quota" can completely change what works for their family
→ Gentle parenting versus permissive, authoritative, and authoritarian parenting
→ Why over-validating a child during a tantrum can sometimes make things worse
→ How to set firm boundaries without shaming or dismissing your child's emotions
→ What to do when your child hits, whines, screams, or becomes completely dysregulated
→ Why parents need to regulate themselves before they can help regulate their children
→ How apologizing after yelling or losing your temper can model accountability
→ Why repair matters more than being a perfect parent
→ How positive reinforcement helps shape behavior without creating shame
→ What emotional resilience actually looks like as children grow
→ Dr. Mona's approach to evidence-based medicine without fear mongering
→ The parenting myths she is most tired of correcting online
→ What she hopes her own children understand about their childhood when they're adults
Follow Dr. Mona!Instagram: @pedsdoctalk
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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Secondary Infertility After a C-Section: Dr. Mona's Journey to IVF
2026/09/23
WARNING: This episode includes detailed discussion of traumatic birth, a NICU stay, a newborn stroke and seizures, maternal sepsis, repeat surgeries, and fear of dying in childbirth.
What happens when the birth experience you imagined becomes a medical emergency, and the journey to growing your family takes a turn you never expected?
In this deeply personal episode of Trying, Dr. Sasha Hakman sits down for part 1 of 2 episodes with pediatrician and mother of two Dr. Mona Amin, known as Dr. Mona of PedsDocTalk, to discuss her journey through birth trauma, a NICU stay, secondary infertility, IVF, and the emotional work of healing after an unexpected birth experience.
Dr. Mona shares the terrifying complications surrounding the birth of her son, including an emergency during her C-section, his neonatal stroke and seizures, and her own life-threatening postpartum complications. Despite being a physician herself, she describes what it felt like to have her symptoms dismissed and the importance of advocating for yourself when something doesn't feel right.
When she and her husband decided to try for a second child, Dr. Mona discovered that scar tissue from her previous surgeries had caused a hydrosalpinx, a fluid-filled, blocked fallopian tube that complicated her ability to conceive. She takes us through the decision to pursue IVF, the emotional weight of having only one viable embryo, and the eventual birth of her daughter.
Together, Dr. Sasha and Dr. Mona explore the grief that can accompany an unexpected birth experience, the impact of medical trauma on both parents, and why motherhood, bonding, and healing do not have to look the way we originally imagined.
In this episode
A C-section that turned into an emergency, and what her ER-doctor husband saw in the OR
Spotting her newborn's seizures when staff first missed them
Being dismissed as "dramatic" in the hospital where she worked
Seeking accountability and protocol changes rather than a lawsuit
Secondary infertility, hydrosalpinx, and choosing IVF
Seven eggs, four fertilized, one blastocyst: her "miracle embryo"
Why her second postpartum complication finally led to a diagnosis
Deciding their family is complete
Why doctor-patients may feel more fear, not less
EMDR, therapy, and how both parents processed the trauma
Naming grief as the loss of an expectation, and why bonding lasts a lifetime
Follow Dr. Mona!Instagram: @pedsdoctalk
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors!
Go to https://olliesmile.com and enter code TRYING at checkout for 10% off your order!
Use my link at thrivemarket.com/trying to get $20 off your first three orders — That covers your membership fee! Sign up now before this exclusive offer ends
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timeline.com/SASHA and 20% off your Mitopure® Gummies.
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In this solo Q&A episode of Trying with Dr. Sasha Hakman, Dr. Sasha answers listener questions across fertility, IVF, embryo transfer, hormone health, pregnancy, exercise, and reproductive genetics.
From adenomyosis treatment before embryo transfer and ways to support a short luteal phase to whole genome sequencing, balanced translocations, IVF in your 40s, male factor infertility, and exercise during treatment, Dr. Sasha breaks down what the evidence tells us, where the research is still limited, and why fertility care often needs to be highly individualized.
As always, this episode is for general education and is not personal medical advice.
In this episode, we cover:
➜ Adenomyosis, why it can affect implantation, and when Depo Lupron and letrozole may be considered before embryo transfer
➜ Using Inito to track FSH, LH, estrogen, and progesterone, confirm ovulation, and potentially identify a luteal phase defect
➜ Whole genome sequencing of embryos, polygenic risk scores, monogenic conditions, Juniper Genomics, Orchid, Nucleus, and the limitations of embryo genetic testing
➜ Persistent chronic endometritis after doxycycline, when additional antibiotics may be needed, and where EMMA/ALICE testing may have a role
➜ Resistance training, powerlifting, pelvic floor health, urinary incontinence, prolapse, and what researcher Margie Davenport's work suggests about exercise in pregnancy
➜ Balanced translocations, genetic counseling, untested embryos, embryo biopsy and re-freezing, and how maternal age can influence decisions around PGT
➜ Vaginal estrogen and the vaginal microbiome, Evvy testing, and using progesterone supplementation to support a short luteal phase
➜ Reproductive immunology after miscarriage or failed embryo transfer, plus when a rheumatologist or reproductive immunologist may be helpful
➜ ICSI for male factor infertility, high AMH, reproductive urology, varicoceles, hypothalamic amenorrhea, restoring ovulation, and trying to conceive after losing your period
➜ Fertility and IVF in your 40s, including the realities of egg quality, ovarian reserve, repeated IVF cycles, and when donor eggs may enter the conversation
➜ Pregnancy symptoms that deserve evaluation, including ocular migraines, shortness of breath, severe fatigue, low ferritin, and iron deficiency
➜ IVF add-ons including Neupogen, hCG washes, steroids, IV intralipids, and uterine PRP, and why limited evidence does not always stop patients with recurrent implantation failure from considering them
➜ Luteal phase ovarian stimulation, estrogen and testosterone priming, diminished ovarian reserve, follicle synchronization, and individualized stimulation protocols
➜ Exercise during ovarian stimulation and after frozen embryo transfer, plus microdose Lupron protocols, FSH stimulation, hCG triggers, and OHSS risk
CHAPTERS
00:00 Solo Q&A and a reminder about general medical advice01:00 Adenomyosis treatment before transfer and tracking ovulation with Inito08:03 Whole genome sequencing, embryo genetics and chronic endometritis13:55 Resistance training, pelvic floor health, balanced translocations and untested embryos20:44 Vaginal estrogen, the microbiome and lengthening the luteal phase23:44 Reproductive immunology, ICSI and male factor infertility27:29 Hypothalamic amenorrhea and trying for another baby in your 40s30:34 Migraines in pregnancy, iron deficiency and IVF success in the mid to late 40s35:22 Neupogen, IVF add-ons and luteal phase stimulation39:06 Exercise during IVF and after embryo transfer, plus microdose Lupron protocols
Episodes and experts mentioned:
Whole genome sequencing with Juniper Genomics CEO Jeremy Greco
IVF medications
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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Fetal Movement, Kick Counts & Stillbirth Prevention with Count the Kicks
2026/09/09
Stillbirth is a topic many expectant parents are afraid to talk about, but understanding your baby’s movement patterns can be an empowering tool during pregnancy.
In this episode of Trying with Dr. Sasha Hakman, Dr. Sasha sits down with Karina Bennett, ambassador for Count the Kicks, a stillbirth prevention program created by Healthy Birth Day, Inc. Karina shares the story of losing her son to stillbirth and how that experience led her to advocacy, education, and a mission to help other families recognize changes in fetal movement before it is too late.
Together, Sasha and Karina break down what kick counting actually looks like, when to start, what counts as movement, and why knowing your baby’s individual pattern matters more than comparing your pregnancy to someone else’s. They also discuss anterior placentas, decreased fetal movement, advocating for yourself when something feels wrong, the limitations of at-home Dopplers, and why seeking evaluation is never an overreaction.
This conversation is not about creating fear. It is about giving pregnant women information they can use to feel more connected to their baby, more confident in what is normal, and more empowered to speak up when something changes.
In this episode, we cover:
→ Karina’s personal experience with stillbirth and how losing her son led her to Count the Kicks and stillbirth prevention advocacy
→ Why talking about stillbirth does not have to be fear-based and how education can help expectant parents feel more empowered during pregnancy
→ What fetal movement can tell you about your baby’s well-being and why changes in your baby’s normal pattern deserve attention
→ When to begin tracking fetal movement in the third trimester and how recommendations may differ for higher-risk pregnancies
→ What actually counts as a “kick,” including jabs, rolls, swishes, and other movements
→ Why the goal is not simply reaching a universal number of kicks, but learning how long it typically takes your individual baby to reach 10 movements
→ How the free Count the Kicks app tracks movement patterns, timing, and movement strength over time
→ How tracking fetal movement may reduce anxiety, create reassurance, and help parents bond with their baby during pregnancy
→ What an anterior placenta can mean for your perception of fetal movement and why knowing your own baby’s pattern is still important
→ Why hearing a heartbeat with an at-home Doppler does not replace evaluation for decreased fetal movement or testing like a nonstress test
→ What to do when your baby’s movement pattern changes and why you should never worry about being a burden for asking to be evaluated
→ How to advocate for yourself if you feel dismissed by a provider, including seeking another provider or going to labor and delivery when something does not feel right
→ The ripple effect of pregnancy loss on mothers, fathers, siblings, grandparents, and entire families, and why partners need space and support to grieve too
→ Finding support after stillbirth through therapy, community, advocacy, creative outlets, and giving yourself space to process an unimaginable loss
Learn more about Karina + Count the Kicks
Count the Kicks is a free fetal movement tracking resource designed to help expectant parents learn their baby’s normal movement patterns during the third trimester.
Instagram: @countthekicksusDownload the free Count the Kicks app on iOS or Android.
Stay connected with Dr. Sasha
Follow Trying with Dr. Sasha Hakman for honest, expert-led conversations about fertility, pregnancy, reproductive health, and everything that comes with trying to grow a family.
Subscribe wherever you listen to podcasts and on YouTube @tryingpodwithdrhakman.
Have a question or a topic you want Dr. Sasha to cover? Leave it in the comments or submit it for an upcoming episode.
New episodes drop every Wednesday.
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Join the newsletter for fertility education, reproductive health insights, episode updates, and more from Dr. Sasha.
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OHSS: What You Need to Know Before IVF or Egg Freezing
2026/09/02
Ovarian hyperstimulation syndrome, or OHSS, is a potential complication of ovarian stimulation that Dr. Sasha believes every patient going through IVF or egg freezing should understand. After seeing thousands of women comment that they wished they had known about OHSS before treatment, she knew it deserved a deeper conversation.
In this solo episode, Dr. Sasha breaks down what OHSS actually is, why it happens, who is most at risk, and the steps fertility doctors can take to help prevent it. She explains the important role trigger shots play, the difference between mild and more serious cases, and the symptoms patients should know to look out for. She also opens up about her own experience with OHSS and shares what she’s learned from managing it in her patients.
In this episode:
What OHSS is and why it happens after ovarian stimulation
Who may be at higher risk during IVF or egg freezing
Why the HCG trigger can increase the risk of OHSS
How fertility protocols can be adjusted to help prevent it
What symptoms to watch for and when to contact your doctor
Dr. Sasha’s personal experience with OHSS and what recovery can look like
The biggest takeaway: OHSS shouldn’t be something you first learn about after it happens. The more you understand your risk factors and treatment options, the better equipped you are to have informed conversations with your doctor throughout your fertility journey.
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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How to Get in Shape After Baby: Postpartum Fitness, Nutrition & Strength with Samantha Christine
2026/08/26
Getting stronger after pregnancy is not about "bouncing back." It is about rebuilding your body, fueling it properly, and creating habits you can actually maintain. In this episode, Dr. Sasha sits down with certified personal trainer and nutritionist Samantha Christine to talk about postpartum body recomposition, strength training, nutrition, macros, GLP-1 medications, and what it really takes to feel strong and confident in your body again. Samantha also opens up about her own postpartum transformation, losing her period at a very low body fat percentage, and why she now encourages women to chase strength instead of a number on the scale.
In this episode, we cover:
→ Samantha's postpartum transformation, how she lost 18% body fat through nutrition and progressive overload, and why meaningful body recomposition takes time
→ Why we need to move away from "bounce back" culture and give the body time to recover after pregnancy, birth, and breastfeeding
→ Where to start with postpartum nutrition, including adequate calories, protein, healthy fats, carbohydrates, fiber, whole foods, and why cutting calories too quickly can backfire
→ Body recomposition and progressive overload explained, plus why building lean muscle can completely change your body even when the number on the scale barely moves
→ How to start tracking macros without becoming overwhelmed, including Samantha's approach to protein intake and why calories alone do not tell the full story
→ Why some women may actually be undereating, what basal metabolic rate (BMR) means, and how chronically low calorie intake can interfere with energy, training, and body composition goals
→ GLP-1 medications, the rise of "skinny culture," and the potential consequences of using weight loss medications to become increasingly lean, including menstrual cycle loss and concerns about bone health
→ Samantha's experience losing her period for 13 months at approximately 11% body fat and why being smaller did not ultimately mean being stronger or healthier
→ How to balance cardio and strength training without sacrificing muscle, including the nutrition strategy Samantha used while training for a Half Ironman
→ Reverse dieting explained, why Samantha gradually increases calories for some clients who have been chronically undereating, and why eating more can sometimes be part of improving body composition
→ How busy women and moms can make fitness sustainable with simple 30 to 45 minute workouts, compound movements, at-home options, and realistic goals
→ Why consistency matters more than perfection, how long to give a new nutrition and fitness routine before judging your progress, and why the best plan is one you can still follow on your worst days
→ How motherhood can shift the motivation to exercise from simply changing your appearance to taking care of your children's mother and modeling healthy behaviors for your family
Follow Samantha Christine!
Instagram: @samcfit_
Listen to the EMPWR Podcast and find Samantha's Elevate fitness and nutrition app for more from Samantha.
Follow Dr. Sasha!
TikTok: @sashahakmanmd @tryingwithdrhakman
Instagram: @sashahakmanmd @tryingwithdrhakman
YouTube: @sashahakmanmd
Want to receive my weekly newsletter?
Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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The IVF Protocol No One Explains: What Actually Determines Your Results
2026/08/19
IVF medication protocols can be one of the most confusing parts of fertility treatment. In this solo episode, reproductive endocrinologist Dr. Sasha Hakman explains how IVF medications actually work, why different patients may need different stimulation protocols, and how factors like AMH, ovarian reserve, age, previous IVF response, and risk of ovarian hyperstimulation syndrome (OHSS) influence treatment decisions.
In this episode, we cover:
How the hypothalamic-pituitary-ovarian (HPO) axis controls the menstrual cycle, including the roles of gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), estrogen, and progesterone
How IVF medications recruit multiple follicles and why AMH, antral follicle count, and ovarian reserve influence your stimulation protocol and medication dose
The main IVF stimulation medications, including recombinant FSH, human menopausal gonadotropin (hMG/Menopur), GnRH agonists, GnRH antagonists, and hCG
How IVF trigger shots work, including Lupron vs. hCG, dual or co-triggers, double Lupron triggers, final egg maturation, and meiosis
The antagonist IVF protocol, how Ganirelix and Cetrotide help prevent premature ovulation, and why this is one of the most commonly used IVF protocols
Ovarian hyperstimulation syndrome (OHSS), how hCG and vascular endothelial growth factor (VEGF) contribute to risk, and why trigger selection matters for high responders
The microdose Lupron flare protocol, who may benefit from it, and why Dr. Sasha often considers it for diminished ovarian reserve or a previous poor response to IVF stimulation
The long Clomid protocol, Provera protocols, and mini IVF, including when lower-dose stimulation may make sense and why mini IVF does not automatically mean better egg quality
IVF add-ons including letrozole, Clomid, and Omnitrope (growth hormone), what the research actually shows, and why letrozole may be useful for breast cancer, endometriosis, and other estrogen-sensitive conditions
IVF priming with birth control, estrogen, testosterone or AndroGel, and growth hormone, plus why Dr. Sasha does not routinely recommend DHEA supplementation
How estrogen priming and luteal-phase starts may help patients with diminished ovarian reserve (DOR) prevent early follicle recruitment and improve follicle synchrony
Why a previous IVF cycle can provide valuable information for choosing your next protocol, and the surprising research on repeating the same IVF protocol vs. switching protocols after a poor response
Why there is no single “best” IVF protocol and when individualized protocols may matter most, particularly for patients approaching or over 40, diminished ovarian reserve, poor egg maturity, or previous failed IVF cycles
Episodes Dr. Sasha mentions:
IVF 101: A foundational breakdown of IVF, follicle development, and the IVF process
Dr. Sasha's IVF cycles at 32 and 37: Dr. Sasha shares the different medication protocols she personally used and how her blastocyst yield compared between cycles five years apart
Quick terminology guide:
HPO axis = hypothalamic-pituitary-ovarian axis | GnRH = gonadotropin-releasing hormone | FSH = follicle-stimulating hormone | LH = luteinizing hormone | AMH = anti-Müllerian hormone | hMG = human menopausal gonadotropin | hCG = human chorionic gonadotropin | OHSS = ovarian hyperstimulation syndrome | VEGF = vascular endothelial growth factor | DOR = diminished ovarian reserve
Follow Dr. Sasha!
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Dr. Mamina Turegano on Hormonal Acne, Hair Loss & Skincare That Works
2026/08/12
We share more with a reproductive endocrinologist than you'd think — hormones drive skin and hair just as much as fertility. In this episode, Dr. Sasha sits down with triple board-certified dermatologist Dr. Mamina Turegano to break down what's really behind hormonal acne and hair loss, the environmental factors quietly wrecking our skin, and the exact prescriptions, supplements, and skincare routines that actually work.
In this episode, we cover:
Why acne is so common (80-90%+ of women experience it) and why it's rising in adulthood
The environmental theories behind the "acne epidemic" — diet, sugar, dairy, fiber intake, caffeine, microplastics, and endocrine disruptors
Why chronic stress, poor sleep, and constant phone/screen stimulation are affecting our hormones and skin
How to tell if your acne is truly "hormonal" — jawline breakouts, cystic bumps, and the testosterone-to-estrogen ratio (not the absolute number) that drives flares
PMOS (formerly PCOS) and how androgen imbalances show up as cystic acne, hirsutism, and hair loss
Dr. Turegano's diagnostic workup: history, hormone testing, functional medicine referrals, Dutch tests, and gut microbiome testing
The acne treatment ladder — topical retinoids, spironolactone, isotretinoin (Accutane), and where supplements like omega-3s, zinc, pumpkin seed oil, vitex, and DIM fit in
Why the type of progestin in your birth control can make acne better or worse — and the role of drospirenone (Yasmin)
Coming off birth control or spironolactone without your skin spiraling
Normal vs. abnormal hair shedding, telogen effluvium vs. androgenic alopecia, and why postpartum hair loss hits so hard
The most common hidden cause of hair loss: iron deficiency (even without anemia) — plus the trick to actually absorbing your iron supplement
Dr. Turegano's hair loss lab panel: thyroid (TSH, free T3/T4, antibodies), vitamin D, zinc, ANA, ferritin, and androgens
Hair growth treatments ranked: topical and oral minoxidil, finasteride/dutasteride, spironolactone, and the supplements worth trying (Nutrafol, Viviscal Pro, biotin myths)
The truth about biotin — why it can mask a real heart attack on lab testing
Building a skincare routine: cleanser, moisturizer, sunscreen as the non-negotiable foundation, plus where retinoids and vitamin C serums fit in
Dr. Turegano's personal AM/PM skincare routine and product picks
Follow Dr. Mamina Turegano! Instagram/social: @dr.mamino
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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Secondary Infertility Causes, Diagnosis & Treatment: Everything You Need to Know
2026/08/05
Secondary infertility affects millions of women — and yet it remains one of the most isolating diagnoses in the fertility space. You already have a child, so you feel like you can't complain. But the confusion, grief, and frustration are completely real. In this solo episode, Dr. Sasha Hakman breaks down exactly what secondary infertility is, why it happens, and what to do about it — including causes that will genuinely surprise you. If you've been pregnant before and are struggling to get pregnant again, this episode was made for you.
In this episode, we cover:
What secondary infertility actually is by definition — and why pregnancy loss counts too, even if you never brought a baby home
Ovulatory dysfunction: why it's the #1 cause of secondary infertility, how PCOS, thyroid disease, and high prolactin play a role, and how postpartum weight changes can quietly shut down ovulation
How to track your cycle and confirm ovulation at home — including Dr. Sasha's favorite tools (Inito, LH strips, and progesterone testing)
The age factor no one talks about enough: what the statistics actually say about childless-not-by-choice rates for women 35–40 and 40+
Premature ovarian insufficiency (POI): why some women enter early menopause between babies — and why waiting too long between pregnancies can dramatically change your options
Tubal disease and endometriosis: how tubes that were once open can become blocked between pregnancies, and what an HSG actually involves
Uterine factors: fibroids, polyps, Ashman syndrome, and why a saline infusion sonogram catches what a regular ultrasound misses
Male factor infertility: why "he already has kids" is not a reason to skip the semen analysis, and how sleep deprivation, weight gain, and lifestyle changes after baby can tank sperm quality
Unexplained secondary infertility: why it's the most frustrating diagnosis, and how Dr. Sasha expands her workup to look for hidden endometriosis, insulin resistance, and sleep disruption
C-sections and fertility: what a meta-analysis of 600,000 women found about C-section's impact on subsequent pregnancy and live birth rates
Isthmocele explained: what it is, how a C-section scar defect can trap fluid and create a hostile environment for embryos, and how it's diagnosed and treated
Why Dr. Sasha pursued a VBAC after her first C-section — and the fertility reasoning behind that decision
The full diagnostic workup for secondary infertility: what your doctor should be evaluating and what to ask for if they're not
Treatment options: from super ovulation with IUI to IVF, to surgical correction of structural issues — and how the approach depends entirely on what the workup reveals
Why breastfeeding may be the simplest thing standing between you and your next pregnancy
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
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The Truth About Cycle Syncing, Fasted Training & Building Muscle After 40
2026/07/29
Most women have been told at some point that their menstrual cycle should dictate how they train, that fasted workouts are wrecking their hormones, or that muscle-building becomes nearly impossible after 40. In this episode, Dr. Sasha Hakman sits down with researcher and women's health expert Dr. Lauren Colenso-Semple to separate what the science actually shows from what the fitness industry is selling. They break down why cycle syncing isn't backed by the data, whether fasted training really matters, how much protein your body can actually use at once, and what's really true (and not true) about building muscle in perimenopause and menopause. If you've ever felt confused, discouraged, or like you needed to buy one more program to finally "get it right," this episode is for you.
In this episode, we cover:
Why the fitness industry profits from confusion — and how "cycle syncing" programs oversell the effect of hormones on your training
Fasted vs. fed training: does it affect fat loss, muscle growth, or strength adaptations? (Spoiler: no)
Low energy availability explained — who's actually at risk, and why it's different from simply training fasted
The truth about the "anabolic window" and post-workout protein timing
How much protein your body can actually use in one sitting, and why more isn't always better
Why weight training under stable, loaded conditions beats unstable-surface or "functional" exercises for building muscle
Understanding "the neighborhood of failure" — how close to failure you really need to train, and how to get started if you're intimidated by the weight room
Rep ranges myths: why sets of 5 and sets of 25 can build the same amount of muscle
Does the menstrual cycle affect training performance or adaptation? What the actual research says (not the extrapolated animal studies)
Hormonal birth control, "brain changes," and exercise capacity — what's real and what's not
Why so much of exercise science excluded women — and why that gap is closing faster than the internet gives it credit for
Testosterone and muscle growth: why massive differences in testosterone levels between men and women don't translate to massive differences in ability to build muscle
Can you make up for "lost time" if you didn't start lifting until your 40s, 50s, or later?
Menopause and muscle: does estrogen decline really make it harder to build muscle, and does hormone therapy change that?
Supplements that are actually worth your money — creatine dosing, why BCAAs are a waste, and why collagen is a poor protein source for muscle
Whey vs. pea protein, jumping for bone health, and whether weighted vests actually do anything
The single biggest myth stopping women from reaching their fitness goals
Follow Dr. Lauren Colenso-Semple! Instagram: @drlaurencs1
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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What IVF Protocol Did a Fertility Doctor Choose for Herself?
2026/07/22
You asked for it, and here it is. In this solo episode, Dr. Sasha Hakman walks through her own two IVF cycles in full detail — the exact medications, doses, trigger decisions, lab outcomes, and the reasoning behind every choice she made. As a reproductive endocrinologist who has navigated IVF both as a clinician and a patient, she brings a level of transparency you rarely get from a doctor. From a purely elective embryo freeze at 32 to a second retrieval at 37, this episode breaks down what actually goes into building a family through IVF — and helps you understand your own protocol along the way.
In this episode, we cover:
Why Dr. Sasha chose to freeze embryos at 32 — before she was ready to have children — and the reasoning behind creating embryos vs. freezing eggs
Her diagnosis of Non-Classical Congenital Adrenal Hyperplasia (NCAH), what it is, and how it contributed to her ovulatory dysfunction
Her baseline fertility stats: AMH of 4 ng/mL and 30+ follicles — even while on continuous birth control pills
Cycle 1 at age 32: antagonist protocol, 275 units of Gonal-F + 75 units of Menopur, and why she chose a combination Lupron + low-dose hCG trigger The OHSS she developed after her first retrieval — how bad it got, and how she managed it at home
Why she got 26 eggs but only 11 were mature — and why she was so disappointed with that outcome
Cycle 2 at age 37: what changed in her protocol, and what the data from cycle 1 taught her
Final embryo outcome: 6 blastocysts, 3 euploid (1 male, 2 female), 3 aneuploid
ICSI — why she chose it even without a male factor diagnosis, and the case for doing it even when sperm looks great
Assisted hatching — what it is, why she opted in, and the small but real risk of monozygotic twinning
PGT-A genetic testing — how it works and why she would never transfer an aneuploid embryo
Delayed vs. immediate egg stripping — an inside look at embryology lab practices most patients never hear about
What she did NOT add to her protocol — no growth hormone, no embryo glue — and why she kept it evidence-based and simple
The future of IVF: personalized genetic protocols that could one day predict how your ovaries will respond before your first injection
Pregnancy update: 23 weeks, scheduled for a fetal echo, and feeling every bit of the third trimester
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more!
If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week.
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Does a Hysterectomy Cure Endometriosis? An Endo Surgeon Answers Your Top Googled Questions
2026/07/15
Endometriosis affects at least 1 in 10 women, yet the average patient waits years for a diagnosis — often after being told their pain is normal. In this episode, Dr. Sasha Hakman sits down with board-certified OB/GYN and endometriosis surgeon Dr. Mallory Stuparich to break down what endometriosis actually is, why it's now understood as a systemic immune and neuro-inflammatory condition rather than a purely hormonal one, and how patients can push back when they're being dismissed. If you've ever been told your pain is "just part of being a woman," this episode is for you.
In this episode, we cover:
What endometriosis actually is — and why "endometrial-like tissue" outside the uterus is now understood as part of a systemic neuro-inflammatory and neuro-immune disorder, not just a hormonal one
Why endometriosis so often overlaps with mast cell activation, POTS, Ehlers-Danlos syndrome, autoimmune conditions, and migraines
The leading theories on what causes endometriosis, and why retrograde menstruation alone doesn't explain it
Normal period pain vs. abnormal period pain — and the questions to ask yourself to know the difference
Red flag symptoms beyond pelvic pain: GI issues (painful bowel movements, incomplete emptying, bleeding), bladder urgency, pelvic floor dysfunction, painful sex, and brain fog
Why the amount of pain a patient feels doesn't always correlate with how much disease is actually present
What a real diagnostic workup looks like, and why a "normal" ultrasound or MRI does not rule out endometriosis
Post-surgical hormone therapy — why suppression after excision matters, and who isn't a candidate
Adenomyosis explained: what it is, how it differs from fibroids, and treatment options including adenomyomectomy, uterine artery embolization, and microwave ablation
The links between endometriosis, infertility, and miscarriage — including why 50% of women with endo do not experience infertility
Recurrence after excision surgery, and why what looks like "recurrence" is often incomplete removal the first time around
Lightning round: Is endometriosis genetic? Can you have it with completely normal labs and imaging? Does a hysterectomy cure it? Can it still affect you after menopause?
Follow Dr. Mallory Stuparich! Instagram/social: @MalloryStuparichMD
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
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Podcast reviews
Read Trying to Conceive with Dr. Sasha Hakman podcast reviews
4.8 out of 5
24 reviews
★★★★★
habanero_sauce 2026/10/10
Genuinely helpful
This is my favorite fertility podcast because it really gets into the mechanistics, research methodologies, and details that help you wade through the...
★★★★★
Zoë Alberta 2026/06/27
So informative
I love this podcast! Dr. Hakman clearly cares so much about her patients and getting this important information out to all women/people trying to conc...
★★★★★
Banana Anna 123 2026/04/28
Endo
I so respect you and all of the education you were bringing our way! I just listen to the endometriosis episode, and it was so much more informative a...