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My son was nonverbal. I was told he would never speak, and that if a child does not talk by five, he never will. Jimmy started talking at eight. This is the 11-minute version of my episode on autism recovery: the stories you never hear, what recovery means, how Jimmy started talking, and the five things it takes. THE FULL EPISODE (26 minutes) YouTube: https://www.youtube.com/watch?v=Ib0cyR6MJCE Podcast: episode 40, Autism Recovery Explained, in the Biohacking Autism feed THE LABS TO START WITH + THE COMMUNITY WAIT LIST https://biohacking-autism.kit.com/d9c8b01fd7 One sign-up. You get the exact baseline panel from this episode in one email, the episode summaries every week, and, if you tick the box, a place on the wait list for the private community. IN THIS VERSION The recovery stories you never see on social media, and why Two sons, same house, same protocol, one recovered What recovery means and what it does not (the truck analogy) Where Jimmy is today, 22 years in The speech window I was given at Stanford, and why there is no window How Jimmy started talking at eight: Dr. Klinghardt and Babesia The five things it takes, in order Three things to do this week, not five WHAT YOU WILL HEAR Jimmy is not recovered. We have made real progress, and the work continues at 22. Artemisinin was one herb used under Dr. Dietrich Klinghardt's care alongside pharmaceuticals, for an infection that had been identified. No doses or sources are given, and this is not a recommendation to buy it. The recovery stories are what parents told me directly and what I saw myself. They are not a study. RELATED EPISODES Autism Biology From a Completely Different Point of View (the baseline): https://www.youtube.com/watch?v=s8fnI3xC0ts The 6 Step Healing Order for Sensitive Autism Kids: https://www.youtube.com/watch?v=yEbHibq0q9g MENTIONED Jenny McCarthy, Louder Than Words · Dr. Dietrich Klinghardt · Dr. Dayan Goodenowe FURTHER READING Fein D, et al. Optimal outcome in individuals with a history of autism. J Child Psychol Psychiatry. 2013;54(2):195-205. PMID 23320807. Kang DW, et al. Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota. Sci Rep. 2019;9:5821. CONNECT biohackautism.com · [email protected] · Instagram @biohackautism · TikTok @biohackingautism · linkedin.com/in/nadiaelkhatib If you know one parent who was given a deadline and zero tools, send them this episode. DISCLAIMER One family's experience and what other parents told me directly. Not medical advice, no doses or treatment instructions. Please discuss any testing or treatment with a qualified clinician. I'm not a doctor. I'm a mother who has been doing this for more than 20 years. CHAPTERS 0:00 Recovery is possible. I've seen it. 1:24 Why you never hear these stories 2:31 Two sons, same protocol, one recovered 3:09 What recovery means 4:24 The truck analogy 4:51 Where Jimmy is today 5:33 How Jimmy started talking 6:06 Dr. Klinghardt and Babesia 7:19 The five things it takes 8:39 What to do this week 10:06 For the caregiver 10:25 The wait list This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

Recovery from autism is possible. I’ve seen it, and my own son isn’t there yet. This is my honest answer after 22 years: the families who got there, why you never hear about them, what recovery means, how my son started talking at eight, and the five things it takes. THE LABS TO START WITH + THE COMMUNITY WAIT LIST https://biohacking-autism.kit.com/d9c8b01fd7 One sign-up. You get the exact baseline panel from this episode in one email, the episode summaries every week, and, if you tick the box, a place on the wait list for the private community. IN THIS EPISODE The recovery stories you never see on social media, and why Two sons, same house, same protocol, one recovered What recovery means and what it does not (the truck analogy) Where Jimmy is today, 22 years in Why there is no one protocol for recovery How Jimmy started talking at eight: Dr. Klinghardt, Babesia and artemisinin The five things it takes, in order Three things to do this week, not five WHAT YOU WILL HEAR Jimmy is not recovered. We have made real progress, and the work continues at 22. Artemisinin was one herb used under Dr. Dietrich Klinghardt’s care alongside pharmaceuticals, for an infection that had been identified. No doses or sources are given, and this is not a recommendation to buy it. The recovery stories are what parents told me directly and what I saw myself. They are not a study. WATCH ON YOUTUBE https://youtu.be/Ib0cyR6MJCE RELATED EPISODES Autism Biology From a Completely Different Point of View (the baseline): https://www.youtube.com/watch?v=s8fnI3xC0ts The 6 Step Healing Order for Sensitive Autism Kids: https://www.youtube.com/watch?v=yEbHibq0q9g MENTIONED Jenny McCarthy, Louder Than Words · Dr. Neil Nathan, The Sensitive Patient’s Healing Guide · Dr. Dietrich Klinghardt · Dr. Dayan Goodenowe FURTHER READING Fein D, et al. Optimal outcome in individuals with a history of autism. J Child Psychol Psychiatry. 2013;54(2):195-205. PMID 23320807. Kang DW, et al. Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota. Sci Rep. 2019;9:5821. CONNECT biohackautism.com · [email protected] · Instagram @biohackautism · TikTok @biohackingautism · linkedin.com/in/nadiaelkhatib If you know one parent who was given a deadline and zero tools, send them this episode. DISCLAIMER One family’s experience and what other parents told me directly. Not medical advice, no doses or treatment instructions. Please discuss any testing or treatment with a qualified clinician. I’m not a doctor. I’m a mother who has been doing this for more than 20 years. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

Caregiver burnout, chronic stress and brain health: the core conversation in a 34-minute Essentials edition for caregivers who want a focused starting point. Dr. Tom O'Bryan joins Nadia Elkhatib to discuss neuroinflammation, the gut-brain axis and the caregiver's long-term health. Nadia brings her family's experience with Alzheimer's disease and more than two decades of parenting her son Jimmy, who has autism, into a conversation about the person doing the caring. This shorter edition follows Tom's framework for the stress response, systemic inflammation versus brain immune activity, blood-brain barrier function, LPS and beta-amyloid. Nadia asks about testing, patterns across years of health records, APOE4 and family history. The conversation also raises questions about overlapping biology in autism and Alzheimer's. Tom's recurring theme is learning the big picture one hour a week, rather than looking for one magic answer. For the extended discussion of food sensitivities, gluten, FODMAPs and everyday exposures, continue with the Full interview. FULL INTERVIEW https://www.youtube.com/watch?v=xTmiaKBItGk ABOUT THE GUEST Tom O'Bryan, DC, CCN, DACBN, CIFM, is a functional medicine educator, founder of TheDr.com, and author of You Can Fix Your Brain and The Autoimmune Fix. BOOKS AND EDUCATION You Can Fix Your Brain: https://thedr.com/you-can-fix-your-brain-book/ Book and audiobook formats (Tom narrates the audiobook): https://www.penguinrandomhouse.com/books/592179/you-can-fix-your-brain-by-dr-tom-obryan-foreword-by-mark-hyman-md/ The Autoimmune Fix: https://thedr.com/autoimmune-fix/ The Inflammation Equation, series registration: https://theinflammationequation.com/ The Gluten Summit: https://thedr.com/the-gluten-summit/ Certified Gluten-Free Practitioner training: https://glutenfreepractitioner.com/ CONNECT WITH DR. TOM + ADDITIONAL RESOURCES Website: https://thedr.com/ Email: [email protected] Consultations (paid service): https://thedr.com/consultations/ Root-Cause Health Deep-Dive + Readiness Form (program-fit form): https://thedr.com/rootcause/ Healthspan vs. Lifespan (commercial testing/consultation packages): https://thedr.com/healthspan-vs-lifespan/ Mentorship for practitioners, nutritionists and coaches: https://thedr.com/mentorship/ MORE RESOURCES FROM THE FULL CONVERSATION The Inflammation Equation workbook/guidebooks and access packages, including paid options: https://theinflammationequation.com/thank-you/ Showerhead-cleaning handout: https://thedr.com/shower/ The Stress of Life by Hans Selye (library record): https://www.ncbi.nlm.nih.gov/nlmcatalog/7605231/ Truly Free Home: https://trulyfreehome.com/ Glass-storage retailers mentioned: https://www.mileskimball.com/ https://www.amazon.com/ https://www.costco.com/ PectaSol is also mentioned in this edition. Product mentions are not a recommendation to copy a regimen. BIOHACKING AUTISM Website and episode library: https://biohackautism.com/ Follow the show in your podcast app and share this episode with another caregiver. DISCLOSURE This episode is not sponsored. Biohacking Autism received no payment or free products and earns no affiliate commission from these links. Tom founded TheDr.com and wrote You Can Fix Your Brain and The Autoimmune Fix; some linked resources are paid offerings. In the Full interview, he describes a friendship with the founder of Truly Free. MEDICAL DISCLAIMER This episode is for educational and informational purposes only. It is not medical advice. Always consult with a qualified healthcare provider before making changes to your health protocol or your child's protocol. Guest perspectives and emerging hypotheses are discussed, not established as universal explanations or individual diagnoses. This conversation does not establish that caregiving causes Alzheimer's disease. No product or program is a promised treatment or cure. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

Caregiver burnout deserves more than being dismissed as "just stress." When you've spent years caring for someone else, what questions should you be asking about your own brain health? Dr. Tom O'Bryan joins Nadia Elkhatib for a full conversation about chronic stress, neuroinflammation and the gut-brain axis. Nadia brings her family's experience with Alzheimer's disease and more than two decades of parenting her son Jimmy, who has autism, into a discussion about the caregiver's long-term health. Tom shares his framework for understanding the sympathetic and parasympathetic nervous systems, systemic inflammation, the blood-brain barrier and brain immune activity. The conversation also covers LPS and beta-amyloid, APOE4 and family history, food sensitivities, gluten versus FODMAPs, and why he reviews patterns across years of test results. The practical thread is his "one hour a week" approach to learning and making gradual changes, rather than searching for a single answer. His explanations include guest perspectives and emerging hypotheses, not a diagnosis of the listener or proof that caregiving causes Alzheimer's disease. ABOUT THE GUEST Tom O'Bryan, DC, CCN, DACBN, CIFM, is a functional medicine educator, founder of TheDr.com, and author of You Can Fix Your Brain and The Autoimmune Fix. BOOKS, SERIES AND HANDOUTS You Can Fix Your Brain: https://thedr.com/you-can-fix-your-brain-book/ Audiobook, narrated by Tom (publisher's format options): https://www.penguinrandomhouse.com/books/592179/you-can-fix-your-brain-by-dr-tom-obryan-foreword-by-mark-hyman-md/ The Autoimmune Fix: https://thedr.com/autoimmune-fix/ The Stress of Life by Hans Selye (library record): https://www.ncbi.nlm.nih.gov/nlmcatalog/7605231/ The Inflammation Equation, series registration: https://theinflammationequation.com/ Workbook/guidebooks and access packages, including paid options: https://theinflammationequation.com/thank-you/ Showerhead-cleaning handout: https://thedr.com/shower/ The Gluten Summit: https://thedr.com/the-gluten-summit/ CONNECT WITH DR. TOM + ADDITIONAL RESOURCES Website: https://thedr.com/ Email: [email protected] Consultations (paid service): https://thedr.com/consultations/ Root-Cause Health Deep-Dive + Readiness Form (program-fit form): https://thedr.com/rootcause/ Healthspan vs. Lifespan (commercial testing/consultation packages): https://thedr.com/healthspan-vs-lifespan/ For practitioners, mentorship: https://thedr.com/mentorship/ Certified Gluten-Free Practitioner training: https://glutenfreepractitioner.com/ HOUSEHOLD RESOURCES MENTIONED Truly Free Home: https://trulyfreehome.com/ Retailers mentioned for glass food storage: Miles Kimball: https://www.mileskimball.com/ Amazon: https://www.amazon.com/ Costco: https://www.costco.com/ Vitality C, PectaSol, B vitamins, fish oils and essential oils are also discussed. Names are provided for identification, not as a recommended regimen. BIOHACKING AUTISM Website and episode library: https://biohackautism.com/ Subscribe and share this episode with another caregiver. RELATED EPISODE MCAS Explained with Dr. Debby Hamilton: https://www.youtube.com/watch?v=-KI678um1GY DISCLOSURE This episode is not sponsored. Biohacking Autism received no payment or free products and earns no affiliate commission from these links. Tom founded TheDr.com and wrote You Can Fix Your Brain and The Autoimmune Fix; some linked resources are paid offerings. He also describes a personal friendship with the founder of Truly Free. MEDICAL DISCLAIMER This episode is for educational and informational purposes only. It is not medical advice. Always consult with a qualified healthcare provider before making changes to your health protocol or your child's protocol. Guest perspectives and emerging hypotheses are discussed, not established as universal explanations or individual diagnoses. No product or program is a promised treatment or cure. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

This is the Essentials edition, a 25-minute cut of our conversation with Dr. Uli K. Chettipally, MD, MPH, an emergency physician, Silicon Valley entrepreneur, and father of Siri, a non-speaking young woman with autism. For the full conversation, see the full episode of Biohacking Autism in this feed. In this edition: what an intensive exercise program did for Siri after she aged out of school at 22, why Uli believes movement acts on the brain through neuroplasticity, how a VR-based exercise system developed for stroke rehabilitation became Cognitive Sensorimotor Therapy, what the n=9 feasibility study measured and what it did not, why a non-speaking person may be able to spell but not speak, how Siri reached the dean's list at College of San Mateo, and the AI Uli is training to reduce the dependence on a trained communication partner. The full episode adds Uli's story of becoming Siri's father, the outcomes study he is planning, how he uses the AI day to day, the touchless letterboard in development, and his smart-home vision for independence. Connect with the guest Sirica Center: https://www.siricacenter.com/ Dr. Uli K. Chettipally on LinkedIn: https://www.linkedin.com/in/ulichettipally Disclosure Dr. Chettipally is the founder of Sirica Therapeutics, which develops the exercise system discussed in this episode. The system is currently used as an exercise machine and has not been evaluated by any regulatory body as a treatment for autism. The research discussed was a small feasibility study measuring tolerance, learnability, and enjoyment, not outcomes. Medical disclaimer This podcast is for educational and informational purposes only and does not constitute medical advice. Nothing in this episode is a recommendation to start, stop, or change any treatment or medication. Please work with your own qualified healthcare professionals when making decisions for yourself and your child. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

Dr. Uli K. Chettipally, MD, MPH, is an emergency physician, a Silicon Valley entrepreneur, and the father of Siri, a non-speaking young woman with autism. In this episode he explains what an intensive exercise program did for Siri after she aged out of school at 22, why he believes movement acts on the brain through neuroplasticity, and how a VR-based exercise system developed for stroke rehabilitation became Cognitive Sensorimotor Therapy. We also cover non-speaking autism and spelling to communicate: how a letterboard failed for Siri at seven and worked at eighteen, why Uli believes the challenge is motor planning rather than intelligence, how Siri got to the dean's list at College of San Mateo, and the AI he is training to reduce the dependence on a trained communication partner. What you'll hear: - Autism and exercise: what changed in anxiety, focus, and weight after Siri started an intensive program - Neuroplasticity and autism: the cognitive, sensory, and motor components of the exercise system - Why a non-speaking person may be able to spell but not speak - The n=9 feasibility study: what it measured and what it did not - Presuming competence, RPM, and letterboards - AI for autism: assistive technology for non-speaking communication - Uli's vision of independence through technology Connect with the guest Sirica Center: https://www.siricacenter.com/ Dr. Uli K. Chettipally on LinkedIn: https://www.linkedin.com/in/ulichettipally Disclosure Dr. Chettipally is the founder of Sirica Therapeutics, which develops the exercise system discussed in this episode. The system is currently used as an exercise machine and has not been evaluated by any regulatory body as a treatment for autism. The research discussed was a small feasibility study measuring tolerance, learnability, and enjoyment, not outcomes. Medical disclaimer This podcast is for educational and informational purposes only and does not constitute medical advice. Nothing in this episode is a recommendation to start, stop, or change any treatment or medication. Please work with your own qualified healthcare professionals when making decisions for yourself and your child. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

What’s driving inflammation in autism? In this Biohacking Autism Essentials edition, Dr. Richard Horowitz walks through the core ideas from his 16-point MSIDS framework and explains how multiple biological systems may contribute to chronic inflammation and symptoms in autism. This shorter, focused edition covers: • The 16-point MSIDS framework • The six “rivers of inflammation” • Neuroinflammation and microglial activation • Gut health, leaky gut, and the microbiome • Mast cell activation and histamine • Mitochondrial dysfunction and the cell danger response • Lyme disease and Bartonella • POTS, dysautonomia, and hypermobility • Autism biomarkers including NfL, GFAP, CRP, VEGF, tau, and p-tau • Why different children may have very different biological drivers Dr. Horowitz’s MSIDS framework was developed for complex chronic illness, not specifically for autism. In this conversation, he explains how he believes the framework may help families and clinicians think more broadly about overlapping contributors to inflammation and chronic symptoms. This is the shorter Essentials edition. For the complete technical discussion, listen to the Full Episode with Dr. Richard Horowitz. CONNECT WITH DR. RICHARD HOROWITZ Get Dr. Horowitz’s new book, Ending Chronic Illness: https://cangetbetter.com/ending-chronic-illness/ Website: https://cangetbetter.com/ Medical Detective Substack: https://medicaldetective.substack.com/ Horowitz Lyme-MSIDS Questionnaire: https://msidsfoundation.org/questionnaire/ For physicians with questions about complex cases: [email protected] MEDICAL DISCLAIMER This episode is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. Always discuss testing and treatment decisions with a qualified healthcare professional. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

Autism inflammation is often discussed as if it were one problem with one cause. In this episode, Dr. Richard Horowitz joins Nadia to walk through his 16-point MSIDS framework for complex chronic illness and discuss how he applies it to questions families and clinicians raise around autism. The conversation covers what Dr. Horowitz calls the six “rivers of inflammation”: infections, environmental toxins, microbiome disruption, intestinal permeability and mast-cell activation, nutrient deficiencies, and sleep. They also explore mitochondrial dysfunction and the cell danger response, neuroinflammation, POTS and dysautonomia, hypermobility, maternal inflammation, and biomarkers including CRP, VEGF, neurofilament light, GFAP, tau, and p-tau. Dr. Horowitz explains why he favors a multifactorial, symptom-guided approach rather than assuming one diagnosis has one underlying mechanism. The discussion includes Lyme and Bartonella, mold, gut-brain signaling, histamine and mast cells, mitochondria, and how different symptoms can point clinicians toward different systems to investigate. The MSIDS framework was developed for complex chronic illness, not specifically for autism. In this conversation, Dr. Horowitz discusses how he believes it may help autism families and clinicians ask broader questions about overlapping contributors to inflammation and chronic symptoms. Connect with Dr. Richard Horowitz: Get Dr. Horowitz’s new book, Ending Chronic Illness: https://cangetbetter.com/ending-chronic-illness/ MSIDS Foundation Dr. Richard Horowitz’s website: https://cangetbetter.com/ Medical Detective Substack: https://medicaldetective.substack.com/ Medical Detective Horowitz Lyme-MSIDS Questionnaire: https://msidsfoundation.org/questionnaire/ MSIDS Foundation For physicians with questions about complex cases: [email protected] Medical Disclaimer: This podcast is for educational and informational purposes only and is not medical advice, diagnosis, or treatment. Always discuss testing and treatment decisions with a qualified healthcare professional. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

This is the 29-minute Essentials edition of my conversation with Dr. Dayan Goodenowe. The full episode, with more on testing, maternal health and where his research is headed, is here: https://biohackautism.com/podcast/dayan-goodenowe-autism-brain-development-plasmalogens/ What does the brain need to build itself, and why does the answer matter for a child with autism and for the parent caring for them? Dr. Dayan Goodenowe, PhD, is a neuroscientist, biochemist and the founder of Prodrome Sciences. In this condensed edition he walks through the brain as a wiring project: raw wires at birth, myelin as the insulation that lets signals stay separate, and why myelination is adaptive rather than pre-programmed. From there he explains why incomplete myelination can make noise and light overwhelming, why children with autism show reduced white matter on imaging, and where neuroinflammation and mitochondrial stress fit in. The middle of the conversation is about plasmalogens: what they are, why the body has to make them in peroxisomes, why they cannot be eaten intact, and how the body spends them like a fire blanket on inflammation. Nadia and Dr. Goodenowe then follow the same biology into later life: age as the main driver of cognitive decline, what ApoE4 actually changes, cortical thickness as the brain's muscle, and why a baseline measurement matters more than a diagnosis. IN THIS EDITION The brain as a wiring diagram: axons, synapses and myelinWhy myelination is adaptive, and why deep sleep is part of itSensory overload explained through incomplete myelinationWe learn by receiving: what that changes for parentsWhat plasmalogens are and why the brain needs themWhy plasmalogens cannot be eaten intactNeuroinflammation, white matter and resilience in autismAutism and Alzheimer's as two ends of the same biologyAge, ApoE4 and when dementia startsCortical thickness: the brain's muscleBaseline testing without obsessing over it CONNECT WITH DR. DAYAN GOODENOWE Dr. Dayan Goodenowe is a neuroscientist and biochemist, the founder of Prodrome Sciences, founder of Dr. Goodenowe's Dietary Therapeutics, and the author of Breaking Alzheimer's. Dr. Goodenowe's education site: https://drgoodenowe.com Prodrome Sciences (for practitioners): https://prodrome.com Dr. Goodenowe has a financial interest in Prodrome Sciences and in plasmalogen products discussed during this conversation. FULL EPISODE Episode 34, the complete conversation: https://biohackautism.com/podcast/dayan-goodenowe-autism-brain-development-plasmalogens/ Episode 28 (solo, hormones and lipids), where this conversation was first previewed: https://biohackautism.com/podcast/autism-blood-work-thyroid-hormones-insulin/ MEDICAL DISCLAIMER This episode is for educational and informational purposes only. It is not medical advice. Always consult with a qualified healthcare provider before making changes to your health protocol or your child's protocol. Several compounds and tests discussed in this episode are investigational or are not FDA-approved for the uses discussed. The plasmalogen precursor program described is in a pre-IND stage of an FDA-regulated development pathway. Biohacking Autism does not provide individualized treatment protocols, dosing instructions, or sourcing guidance for regulated compounds. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

What does the brain need to build itself, and why does the answer matter for a child with autism and for the aging brain? In this episode of Biohacking Autism, Nadia Elkhatib talks with Dr. Dayan Goodenowe, PhD, neuroscientist, biochemist and founder of Prodrome Sciences, about autism brain development, white matter and myelination, mitochondrial dysfunction and brain inflammation in autism, and the lipid raw materials the brain needs to build itself, plasmalogens among them. Dr. Goodenowe reframes the developing brain as a wiring project. Myelin is the insulation that lets signals stay separate, and he explains why incomplete myelination can make a crowded room, a bright store or a loud classroom feel like every conversation arriving at once. He describes what he sees in the white matter of children with autism, why he views many autism-related changes as adaptation rather than attack, and where mitochondrial function and neuroinflammation fit in. From there the conversation turns to plasmalogens: what they do in the brain, why the body has to make them in peroxisomes, why you cannot simply eat them intact, and what plasmalogen precursors are. Nadia and Dr. Goodenowe then follow the same biology into the second half of life: cortical thickness as the brain's muscle, ApoE4 as a question of when rather than whether, what he measures in his testing and imaging work, and why caregiver brain health across decades belongs in the autism conversation. IN THIS EPISODE The brain as a wiring diagram: axons, synapses and myelinWhy myelination is adaptive and why deep sleep is part of itSensory overload explained through incomplete myelinationWhite matter, the corpus callosum and imaging in autismMitochondrial dysfunction and brain inflammation in autismMaternal metabolic health, discussed without blameWhat plasmalogens are and why they matter for the brainWhy plasmalogens cannot be eaten intact, and what precursors areAutism and Alzheimer's as two ends of the same biologyCortical thickness, brain volume and the aging brainApoE4 and when dementia starts, rather than whetherTesting, biomarkers and what a caregiver in their fifties might measureThe Moose Jaw, Saskatchewan community study CONNECT WITH DR. DAYAN GOODENOWE Dr. Dayan Goodenowe is a neuroscientist and biochemist, the founder of Prodrome Sciences, founder of Dr. Goodenowe's Dietary Therapeutics, and the author of Breaking Alzheimer's. Dr. Goodenowe's education site: https://drgoodenowe.com Prodrome Sciences (for practitioners): https://prodrome.com Dr. Goodenowe has a financial interest in Prodrome Sciences and in plasmalogen products discussed during this conversation. MEDICAL DISCLAIMER This episode is for educational and informational purposes only. It is not medical advice. Always consult with a qualified healthcare provider before making changes to your health protocol or your child's protocol. Several compounds and tests discussed in this episode are investigational or are not FDA-approved for the uses discussed. The plasmalogen precursor program described is in a pre-IND stage of an FDA-regulated development pathway. Biohacking Autism does not provide individualized treatment protocols, dosing instructions, or sourcing guidance for regulated compounds. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

More than 600 companies are building autism technology, yet most families have never heard of them. This 20-MIN ESSENTIALS edition condenses my conversation with Dan Feshbach, founder of Multiple and co-founder of TeachTown, into the core ideas families need most. Dan and I explore AI for autism, AAC, assistive technology, communication tools, sensory technology, and what it will take for useful technology to actually reach families. We also talk about why autism technology needs to move at the “speed of family,” why families need trusted tools rather than more shiny objects, and how emerging technology could support communication, work, connection, and greater independence. Dan shares the deeply personal reason this work matters to him. During a letterboard session, his son Reed described his experience in four words: “I live in silence.” His vision of a normal life was not about technology itself. It was about friendship, meaningful work, communication, independence, and being able to move through the world more freely. IN THIS ESSENTIALS EDITION: • Why autism technology needs to move at the “speed of family” • How AI can accelerate development and testing • Why 600+ autism technology companies remain largely invisible to families • The “first mile of capital” problem in autism innovation • Why families need trusted tools, not more shiny objects • AI-powered communication and support tools • Sensory eyewear and screen-free regulation technology • AAC and communication support for nonspeaking people • AI and biomedical pattern recognition • Brain-computer interfaces • Why technology should support a person's life, not become the life • Why waiting another 15 years for meaningful solutions is unacceptable WATCH THE FULL 67-MINUTE CONVERSATION: https://www.youtube.com/watch?v=fZjnQwfAhk0 CONNECT WITH DAN FESHBACH Multiple: https://www.multiplehub.org/ Multiple Autism-Tech Database: https://www.multiplehub.org/autism-tech-database CONNECT WITH BIOHACKING AUTISM Website: https://biohackautism.com/ Instagram: https://www.instagram.com/biohackautism/ LinkedIn: https://www.linkedin.com/in/nadiaelkhatib/ DISCLOSURE Dan Feshbach is the founder of Multiple and discusses companies and initiatives connected to Multiple's accelerator and autism-innovation ecosystem. Biohacking Autism has not independently evaluated or endorsed the companies, apps, devices, technologies, or research programs discussed in this episode. DISCLAIMER This program is for educational and informational purposes only and is not medical advice. Always consult a qualified healthcare professional before making changes to your health protocol or your child's protocol. Emerging technologies and research discussed in this episode may be investigational, early-stage, or not yet validated for autism. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

More than 600 companies are building autism technology, yet most families have never heard of them. What could change if AI, communication tools, sensory technology, and future neurotechnology reached the people who need them? Dan Feshbach, founder of Multiple and co-founder of TeachTown, joins Nadia Elkhatib to explore the hidden world of autism technology. They discuss what families actually need from innovation, why strong ideas often fail before they reach daily life, and how technology may support communication, connection, regulation, employment, and independence. Dan also shares the deeply personal experience that shaped his work. During a letterboard session, his son Reed described his experience in four words: “I live in silence.” His vision of a normal life was not about technology itself. It was about friendship, meaningful work, communication, independence, and being able to move through the world more freely. In this episode: • Why more than 600 autism technology companies remain largely invisible to families • AI and autism, including pattern recognition, faster prototyping, and the limits of current systems • AAC for autism and communication support for nonspeaking people • Assistive technology for autism, including augmented reality, sensory tools, haptic devices, distraction-filtering eyewear, and digital support characters • Why technology should support a person’s life rather than become the life • What makes a useful tool different from a shiny object • Why autism innovation faces a “first mile of capital” problem • What Multiple looks for in founders applying to its accelerator • What mission-aligned investors, donors, mentors, and limited partners can contribute • The future of brain-computer interfaces and minimally invasive communication technology • Why families cannot wait another 15 years for meaningful solutions CONNECT WITH DAN FESHBACH AND MULTIPLE Multiple: https://www.multiplehub.org/ Multiple Autism-Tech Database: https://www.multiplehub.org/autism-tech-database CONNECT WITH BIOHACKING AUTISM Website: https://biohackautism.com/ YouTube: https://www.youtube.com/@BiohackingAutism Instagram: https://www.instagram.com/biohackautism/ LinkedIn: https://www.linkedin.com/in/nadiaelkhatib/ Follow Biohacking Autism on your podcast app, and share this episode with someone who wants a clearer view of the technology, communication tools, and innovation being built for people with autism. DISCLOSURE Dan Feshbach is the founder of Multiple and discusses companies and initiatives connected to Multiple’s accelerator and autism-innovation ecosystem. Biohacking Autism has not independently evaluated or endorsed the companies, apps, devices, technologies, or research programs discussed in this episode. MEDICAL AND EDUCATIONAL DISCLAIMER This episode is for educational and informational purposes only. It is not medical advice. Always consult with a qualified healthcare provider before making changes to your health protocol or your child’s protocol. Emerging technologies and research discussed in this episode may be investigational, early-stage, or not yet validated for autism. ABOUT BIOHACKING AUTISM Biohacking Autism with Nadia Elkhatib explores complex questions affecting people with autism and the families who love them. Through expert conversations, lived experience, and evidence-aware discussion, the podcast examines communication, nervous-system regulation, caregiver health, emerging research, technology, and the practical decisions families face every day. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

A shorter, focused edition of our full John Slattery conversation. Leucovorin, also known as folinic acid, has become one of the most discussed topics in autism research. John Slattery, co-author of the 2018 randomized double-blind placebo-controlled trial of folinic acid in children with autism and language impairment, joins Nadia Elkhatib to explain the essential findings in about 24 minutes. They cover what the trial actually measured, why language and communication mattered, folate receptor alpha autoantibodies (FRAAs), FOLR1, how folate reaches the brain, the reduced folate carrier, testing, and why some children may respond while others do not. John also clarifies what the FDA actually approved in 2026 — FOLR1-related cerebral folate transport deficiency — and why that is not the same as a broad FDA approval of leucovorin for autism. The conversation also addresses a practical question many families raise when their own clinician is unfamiliar with leucovorin, and John describes the access model being developed by Meadow Biosciences. This discussion is descriptive and educational; Biohacking Autism does not provide prescribing or medication-acquisition services. Want the complete science and context? Watch the full 1:41 conversation: https://www.youtube.com/watch?v=VP-Rm0XOLsg Connect with John Slattery Meadow Biosciences: https://www.meadowbiosciences.com/ Research & References 2018 Molecular Psychiatry randomized trial: https://www.nature.com/articles/mp2016168 FDA — FOLR1-related cerebral folate transport deficiency approval: https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-patients-cerebral-folate-transport-deficiency American Academy of Pediatrics — leucovorin and autism interim guidance: https://www.aap.org/en/patient-care/autism/use-of-leucovorin-in-autistic-pediatric-patients/ Disclosure John Slattery is Co-founder, President, and CEO of Meadow Biosciences and has disclosed advisory relationships with BioTess Ingredients, Tesseract Medical Research, and Advanced Powder Dynamics. These relationships are disclosed for transparency. Medical Disclaimer This episode is for educational and informational purposes only. It is not medical advice or an individualized treatment recommendation. Leucovorin is a prescription medication. Individual testing and treatment decisions should be made with a qualified healthcare professional who knows the person’s medical history. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

Leucovorin, also known as folinic acid, has become one of the most discussed topics in autism research. John Slattery, co-author of the 2018 randomized double-blind placebo-controlled trial of folinic acid in children with autism and language impairment, joins Nadia Elkhatib to separate the research from the noise. They unpack what the trial actually measured and found; why folate receptor alpha autoantibodies (FRAAs) may matter; how FOLR1, cerebral folate deficiency, the folate receptor, and the reduced folate carrier affect folate transport to the brain; and why testing has to be interpreted in the context of the individual. John also explains the connections among folate metabolism, methylation, redox balance, and mitochondrial biology, along with the uncertainty around responder and non-responder profiles. They clarify the FDA’s 2026 approval of Wellcovorin (leucovorin calcium) for FOLR1-related cerebral folate transport deficiency — and why that is not the same as a broad FDA approval for autism. Connect with John Slattery Meadow Biosciences: https://www.meadowbiosciences.com/ Research & References 2018 Molecular Psychiatry randomized trial: https://www.nature.com/articles/mp2016168 FDA — FOLR1-related cerebral folate transport deficiency approval: https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-patients-cerebral-folate-transport-deficiency American Academy of Pediatrics — leucovorin and autism interim guidance: https://www.aap.org/en/patient-care/autism/use-of-leucovorin-in-autistic-pediatric-patients/ Disclosure John Slattery is Co-founder, President, and CEO of Meadow Biosciences and has disclosed advisory relationships with BioTess Ingredients, Tesseract Medical Research, and Advanced Powder Dynamics. These relationships are disclosed for transparency. Medical Disclaimer This episode is for educational and informational purposes only. It is not medical advice or an individualized treatment recommendation. Leucovorin is a prescription medication. Discuss testing and treatment decisions with a qualified healthcare professional who knows the person’s medical history. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy

When a child or adult with autism has multiple overlapping health concerns, where do you start, what comes next, and what may need to wait? Scott Forsgren, founder of BetterHealthGuy, joins Nadia to walk through the 16-step roadmap he developed from nearly three decades of navigating complex chronic illness, and to explore what autism families may be able to learn from that framework. The conversation begins with nervous system regulation, mast cells and histamine, detoxification and drainage, and the external environment. Scott then explains why sleep, movement, nutrition, the microbiome, mitochondria, immune modulation, coagulation, microbial burden, dental health, structure, and regeneration may belong in a broader sequence rather than a collection of disconnected interventions. They also discuss mold illness, Lyme disease, MCAS, sensitivity to interventions, why “more aggressive” is not always better, and how autism families can use a chronic-illness framework like this to ask better questions with qualified practitioners. Connect with Scott Forsgren BetterHealthGuy: https://www.betterhealthguy.com/ BetterHealthGuy Podcast: https://www.betterhealthguy.com/podcast Episode Resource Scott Forsgren’s 16-Step Health Recovery Framework and downloadable slides: https://www.betterhealthguy.com/steps Disclosure Scott Forsgren has disclosed relationships with FREmedica / WeAreNIKKI as an advisor, Ravel Health as an ambassador and investor, Prodrome as an affiliate, and advertising relationships through BetterHealthGuy. These relationships are disclosed for transparency. Medical Disclaimer This episode is for educational and informational purposes only. It is not medical advice. Always consult with a qualified healthcare provider before making changes to your health protocol or your child’s protocol. This discussion includes personal experiences, prescription and off-label references, emerging regenerative approaches, and category-level discussion of peptides and peptide bioregulators. It is not a recommendation or individualized treatment plan. This podcast uses the following third-party services for analysis: OP3 - https://op3.dev/privacy