FoundMyFitness

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Rating
4.8
from
4729 reviews
This podcast has
75 episodes
Language
Explicit
No
Date created
2014/02/10
Last published
2022/05/31
Average duration
109 min.
Release period
34 days

Description

A podcast about health, science, nutrition, aging, and fitness.

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Podcast episodes

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#075 Intestinal Permeability: the Bacterial link to Aging, Brain Barrier Dysfunction & Metabolic Disorder
2022/05/31
The intestinal barrier serves as a gatekeeper to the human body. The loss of the health and integrity of this barrier influences multiple aspects of human health – including cardiometabolic function, neurological health, behavior, and more – in surprising and unexpected ways. One of these ways involves lipopolysaccharide, or LPS, a bacterial product that arises in the intestine, and its interaction with far distal tissues and organs via the induction of immune mediators. Dr. Rhonda Patrick was the keynote speaker for the Metabolic Health Summit, held May 5 – 8, 2022, in Santa Barbara, California. Her presentation described the role that intestinal permeability and bacterial products play in aging, inflammation, and chronic disease. Show notes and video CHAPTERS: 06:04 - Introduction 08:12 - Atherosclerosis 13:49 - Brain 16:07 - Circulating LPS and behavior 19:05 - Toll-like receptors and inflammation 24:00 - Factors that affect intestinal permeability 30:10 - Alcohol 32:07 - Gluten 35:21 - Butyrate and dietary fiber 37:48 - Dietary fat 42:21 - Biomarkers of intestinal permeability 43:11 - Omega-3 fatty acids 50:02 - Q&A LEARN MORE: Coinciding with this release, you can now find a variety of deep resources on the FoundMyFitness website for all of the topics covered in this episode. Learn about the blood-brain barrier Learn about intestinal permeability Learn about toll-like receptors Learn about cerebral small vessel disease SUPPORT THE CHANNEL: Many of these magnificent resources exist directly as a result of our premium members. As a premium member, listeners get access to our exclusive podcast The Aliquot, monthly Q&As, a special summary of scientific research every other week called the Science Digest, and more. Sign up to become a premium member and nurture the existence of the FoundMyFitness platform. Become a member
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#074 Dr. Dominic D'Agostino on Developing a Well-Designed Ketogenic Diet and Harnessing Its Benefits
2022/04/28
Dr. Dominic ("Dom") D'Agostino is an expert on a wide range of topics related to metabolic health, ketosis, and ketogenic diets. As one of the world's foremost experts on the ketogenic diet, Dom has personally practiced some variation of ketogenic diet for over a decade, bringing a substantial amount of practical experience along with his anecdotes from human and animal research. In this episode, we discuss: 00:04:59 - What is "keto” (and what it is not) 00:08:42 - Types of ketogenic diets 00:15:27 - Lifestyle Ketogenic Diet 00:26:36 - Biomarkers and hyperlipidemia 00:29:41 - Micronutrients and Supplementation 00:33:40 - Exogenous Ketones 00:55:48 - Optimal blood concentration of ketones (Dom's pick) 01:13:31 - Exercise performance and anti-catabolic effects 01:34:37 - Brain and Memory 01:42:39 - Intermittent Fasting 01:51:43 - Neurodegenerative Diseases 01:58:05 - Migraines 02:04:17 - Autoimmune diseases 02:06:15 - Cancer 02:22:03 - Carnivore diet 02:28:22 - Dom's lifestyle habits 02:31:46 - Measuring ketones Watch this episode on YouTube: https://www.youtube.com/watch?v=RWkv9ad7zvc If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/dominic-dagostino-2 Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor
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#073 Sauna Benefits Deep Dive and Optimal Use with Dr. Rhonda Patrick & MedCram
2022/04/13
This episode features a discussion with MedCram co-founder Kyle Allred on the effects of sauna. I had the pleasure of being interviewed by Kyle on all things sauna science and we're posting that discussion for you here. As an exercise mimetic, sauna use has anti-inflammatory, mood-elevating, and detoxifying properties that research increasingly shows may deliver cardiovascular and brain benefits. The science of sauna use has been a research interest of mine for many years and this discussion is by far one of the most well-rounded discussions I've had on the subject. Thanks to Kyle and MedCram for having me for his interview. In this episode, we'll discuss: 00:00:00 - Introduction 00:02:46 - Summary of sauna benefits 00:10:47 - Heat as an aerobic exercise mimetic 00:14:45 - Effects of heat acclimation on endurance 00:17:37 - Why heat shock proteins may protect against dementia 00:23:20 - The stress-relieving effects of sauna use (personal anecdote) 00:27:43 - Investigating sauna for depression 00:30:32 - Brain-derived neurotrophic factor (BDNF) and endorphins response 00:34:51 - Cellular repair mechanisms elicited by sauna use 00:40:05 - Prevention of muscle atrophy 00:42:45 - Detoxification of heavy metals  00:44:50 - Heart rate variability, a measure of stress resilience 00:46:40 - The synergy of sauna use and exercise 00:52:13 - Cross-cultural and historical prevalence of heat therapy 00:56:12 - Infrared sauna vs. traditional saunas 00:58:31 - Rhonda's personal sauna protocol: duration, temperature, humidity, and frequency 01:03:22 - How jacuzzi, hot baths, and hot showers compare to sauna use 01:06:19 - Hydration, cold therapy, and sauna safety  01:11:18 - Who should not use saunas? 01:15:21 - Does sauna use increase blood sugar levels? 01:17:16 - Limitations of current sauna research and hopes for future research MedCram is a YouTube channel created by Kyle Allred, PA-C and Roger Sehuelt, MD, master educators of health and medical science. Their videos cover important topics such as immunity, metabolism, and vitamin D in an authoritative, but approachable way. Visit the MedCram YouTube channel for more efficient, engaging, fun, and lasting way to learn and review medical topics. Watch this episode on MedCram: https://www.youtube.com/watch?v=RWkv9ad7zvc If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/medcram-sauna Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor
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#072 Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration — can we change the pace?
2022/04/12
Morgan Levine, Ph.D., developed the phenotypic aging clock called PhenoAge and is a Founding Principal Investigator at Altos Labs, a biotech company that seeks to understand the mechanisms that drive the aging process and age-related diseases with the hope of identifying possible interventions. Additionally, Dr. Levine is an assistant professor of pathology at the Yale University School of Medicine, where her research focuses on the science of biological aging. Dr. Levine completed a postdoctoral fellowship with previous guest Dr. Steve Horvath, a pioneer in the field of epigenetic clocks.  In this episode, Dr. Levine and I discuss:  00:01:19 - What is aging and why does it matter to scientists? 00:04:45 - Hallmarks of aging 00:08:59 - The advantage of epigenetic clocks in research 00:19:05 - Epigenetic age acceleration 00:36:40 - Are epigenetic changes in aging a cause or consequence? 00:42:15 - Reversing epigenetic age with interrupted reprogramming techniques 00:49:27 - Therapeutic plasma exchange in aging and pro-aging factors in blood  00:56:01 - Lifestyle factors that accelerate epigenetic age 01:03:23 - Reliability of consumer epigenetic aging tests 01:06:12 - Construct validity of epigenetic clocks 01:12:06 - Thoughts on most exciting research in aging field  01:13:44 - Dr. Levine's lifestyle habits Get the show notes: foundmyfitness.com/episodes/morgan-levine Looking for more?  Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Try thirty days of our FoundMyFitness premium member to get access to exclusive episodes, emails, a live Q+A with Rhonda and more: https://www.foundmyfitness.com/trial
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#071 Peter Diamandis, MD, and Tony Robbins on strategies that promote longevity now – and in the very near future
2022/03/09
Dr. Peter Diamandis is a serial entrepreneur and founder of XPRIZE, a non-profit organization that designs and conducts global competitions that incentivize the development of technological breakthroughs that propel humanity toward a better future.    Tony Robbins is an entrepreneur, bestselling author, philanthropist, and business strategist. He provides business and life coaching to millions of people worldwide through his audio programs, educational videos, and live seminars.    Diamandis and Robbins are a dynamic duo, having paired up with co-author Dr. Robert Hariri to write Life Force, a best-selling book that describes breakthroughs in precision medicine and health technologies that can help people live longer, healthier, more fulfilling lives – in the very near future.   In this episode, Tony Robbins, Peter Diamandis and I discuss… 00:07:09 - How Tony Robbins and Peter Diamandis met  00:18:08 - Tony and Peter discuss their lifestyle habits 00:29:32 - GRAIL cancer screening blood test 00:30:16 - Cleerly AI-driven coronary CT scan  00:36:13 - The role of DNA damage in aging 00:37:25 - Epigenetics, NAD+, and sirtuins 00:44:33 - Interrupted cellular reprogramming 00:52:15 - Longevity escape velocity 00:57:50 - What do we do after longevity is "solved?"  01:04:19 - Space travel, gene therapy, and organogenesis 01:21:48 - Promises and challenges of future technologies 01:26:10 - How mRNA vaccine technology may impact aging Get the show notes: https://www.foundmyfitness.com/episodes/robbins-diamandis Looking for more?  Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Try thirty days of our FoundMyFitness premium member to get access to exclusive episodes, emails, a live Q+A with Rhonda and more: https://www.foundmyfitness.com/trial
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#070 Dr. Eran Elinav on Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut
2022/02/08
Eran Elinav, MD, PhD, is a professor of immunology and principal investigator at the Weizmann Institute of Science in Tel Aviv, Israel, where he co-directs the Personalized Nutrition Project. Dr. Elinav is also a principal investigator at the German Cancer Research Center in Heidelberg, Germany. His research focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease. In this episode, Dr. Elinav and I discuss... 00:06:38 - Circadian rhythm of the microbiome 00:17:17 - Lessons from Hunter-gatherers 00:24:44 - Nurturing the microbiome in children 00:35:16 - Triglycerides and cholesterol 00:38:58 - Saturated fat 00:40:25 - Effect of artificial sweeteners on the microbiome 00:56:10 - What causes recurrent obesity 00:58:17 - Impact of caloric restriction 00:59:26 - Intestinal permeability (gut leakiness) 01:19:54 - Bacteriophage therapy and precision probiotics 01:34:44 - Bacterial role in TMAO risk 01:40:33 - Weight gain from smoking cessation 01:41:53 - Tips for diet personalization Get the show notes: https://www.foundmyfitness.com/episodes/eran-elinav Looking for more?  Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Try thirty days of our FoundMyFitness premium member to get access to exclusive episodes, emails, a live Q+A with Rhonda and more: https://www.foundmyfitness.com/trial
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#069 COVID Vaccine Myths, Questions, and Rumors with Rhonda Patrick and Roger Seheult
2021/09/17
In this nearly 2.5-hour episode, Dr. Rhonda Patrick and Dr. Roger Seheult and Kyle Allred of MedCram make a thoughtful, merit-based, and truly comprehensive discussion of COVID-19 vaccination. In addition to being a co-founder of MedCram Medical Lectures, Dr. Roger Seheult is, as you will find out in the conversation, a boots on the ground, critical care pulmonologist. For Dr. Seheult, COVID-19 is not just theory. He sees real sick people and for that reason brings a very special context to this conversation. Furthermore, Dr. Seheult is also an academic and educator. He is an Associate Clinical Professor at the University of California, Riverside School of Medicine and an Assistant Clinical Professor at the School of Medicine and Allied Health at Loma Linda University. He is quadruple-board certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine and Sleep Medicine through the American Board of Internal Medicine. In this episode, we discuss: 00:00:00 - Introduction 00:06:58 - Vaccination in the young and healthy 00:12:25 - Risk of myocarditis from COVID-19 is greater than for vaccination 00:16:18 - Long-haul COVID is often preceded by mild infection 00:25:36 - The spike protein generated from vaccination is not the same as the viral one 00:34:16 - Biodistribution of vaccine particles 00:41:17 - COVID-19 Vaccine Adverse Event Reporting System (VAERS) 01:06:55 - Antibody-dependent enhancement isn't a concern for the SARS-CoV-2 vaccine 01:14:54 - Do the COVID-19 vaccines damage human fertility? 01:19:51 - Can mRNA vaccines alter human DNA? 01:28:10 - Current ivermectin evidence 01:47:40 - Delta-variant and breakthrough infections 02:01:42 - Viral evolution (virulence vs. immune escape) 02:10:45 - T-cell immunity vs. antibody immunity Watch the annotated video: https://www.youtube.com/watch?v=pp-nPZETLTo Subscribe to MedCram on Apple Podcasts: https://podcasts.apple.com/us/podcast/medcram/id1564795918 Subscribe to MedCram on YouTube: https://www.youtube.com/channel/UCG-iSMVtWbbwDDXgXXypARQ
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#068 Dr. Bill Harris on the Omega-3 Index: Increasing Omega-3 to Promote Longevity & Transform Health
2021/09/10
Dr. William ("Bill") Harris is one of the world's preeminent experts in the field of omega-3 fatty acid research. His work has focused on the roles that fatty acids in play in cardiovascular and neurocognitive health. The author of more than 300 scientific papers on fatty acids and health, Dr. Harris is a professor in the Department of Medicine in the Sanford School of Medicine at the University of South Dakota, the co-inventor of the Omega-3 Index, founder of OmegaQuant Analytics, and president and founder of the Fatty Acid Research Institute. In this episode, Dr. Harris and I discuss… 00:00:00 - Introduction 00:06:36 - Early studies on omega-3s, dietary fats, and cholesterol  00:14:44 - Omega-3s may normalize bleeding times  00:20:33 - Plant-based omega-3s are not equivalent in power to marine omega-3s  00:25:23 - Genetic engineering of plants is needed for sustainable omega-3s in the future 00:27:18 - The omega-3 index reveals individual variations in omega-3 needs 00:32:13 - Red blood cell concentration of omega-3s better reflect long-term omega-3 status 00:36:41 - Genetic variants influence omega-3 dietary needs 00:54:20 - The omega-3 index may predict life expectancy 01:05:03 - How metabolites of omega-3 reduce and resolve inflammation 01:17:11 - High omega-3 concentrations halve the risk of COVID-19 death 01:20:10 - DHA may help keep the SARS-CoV-2 spike protein from entering cells 01:22:50 - Concerns over the omega-6/omega-3 ratio may be unfounded Looking for more?  Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor
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#067 Dr. Ashley Mason on Drug-free Approaches for Treating Depression, Insomnia, and Overeating
2021/09/01
Dr. Ashley Mason is a clinical psychologist and director of the Sleep, Eating, and Affect Laboratory at the Osher Center for Integrative Medicine at UCSF. Her research centers on nonpharmacological approaches for treating depression, insomnia, and overeating. In this episode, we discuss: 00:00:00 - Introduction 00:08:10 - Whole-body hyperthermia (WBH) and sauna use differ 00:17:06 - Depression causes thermoregulatory dysfunction – but sauna use may correct it 00:21:12 - WBH and sauna use may reduce symptoms of depression 00:33:22 - Heating the body slowly may improve heat tolerance and increase WBH effectiveness 00:39:35 - Sauna use may benefit people with depression and cardiovascular disease – which often coincide 00:40:18 - Dr. Mason and Rhonda are collaborating on new research on depression and WBH 00:44:19 - Sauna bathing and similar practices often provide opportunities for people to connect socially 00:53:12 - Common causes of insomnia 01:01:26 - Cognitive behavioral therapy, sleep hygiene, stimulus control, and sleep restriction for treating insomnia Looking for more?  Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor
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#066 Dr. Mark Mattson on the Benefits of Stress, Metabolic Switching, Fasting, and Hormesis
2021/08/24
Dr. Mark Mattson Dr. Mark Mattson is a professor of neuroscience at the Johns Hopkins University School of Medicine and the former chief of the Neuroscience Research Laboratory at the National Institute on Aging. He's one of the most cited neuroscientists in the world, with more than 180,000 citations noted in the scientific literature. Dr. Mattson's work has advanced scientific understanding of brain aging and identified fundamental aspects of neurodegenerative disorders, including Alzheimer’s disease and Parkinson’s disease. His most notable work has focused on how the brain responds to mild stressors, such as those associated with exercise and intermittent fasting. In this episode, we discuss... 00:3:31 - Hormetic stressors drive adaptation and prevent physiological complacency 00:13:00 - Intermittent fasting improves health by promoting metabolic switching 00:16:49 - Daily time-restricted eating vs 5:2 weekly fasting  00:27:44 - A ketogenic diet and intermittent fasting differ in terms of brain effects 00:34:23 - Exercising while intermittent fasting exerts additive effects 00:52:32 - Plant-based bioactive compounds induce hormetic stress 01:10:48 - Severe caloric restriction may compromise muscle mass 01:26:25 - Intermittent fasting in young vs. old and in men vs. in women 01:35:20 - The effects of cortisol differ during a fast versus chronic stress 01:53:36 - Fasting-mimetics like resveratrol and spermidine vs actual fasting 02:08:44 - How ketone supplementation may improve brain health Join over 300,000 people and get the latest distilled information on circadian insights straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor
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#065 Dr. Satchin Panda on Circadian Insights into Exercise Timing, Melatonin Biology, and Peak Cognition
2021/07/05
Dr. Satchin Panda Dr. Satchidananda (Satchin) Panda is a professor in the Regulatory Biology Laboratory at the Salk Institute for Biological Studies.  Dr. Panda’s work focuses on chronobiology, the study of the day-night cycles that drive the multifaceted activities of the human body, using genetic, genomic, and biochemical approaches. He is an expert on circadian rhythms and a pioneer in the field of time-restricted eating. A priority for Dr. Panda when designing his studies is to identify strategies that positively impact public health. In this episode, Dr. Panda and I discuss... 00:00:00 - Introduction 00:04:29 - How circadian rhythms influence human health 00:12:30 - Seeking bright light in the morning and avoiding it in the evening improves sleep 00:20:40 - Supplemental melatonin may counteract evening bright light exposure 00:26:16 - The relationship between melatonin and insulin secretion  00:33:15 - Shift work, jet lag, and modern life contribute to circadian dysfunction 00:45:10 - Naps might aid with afternoon sleepiness and sleep loss 00:47:05 - Indoor lighting can be used to promote healthy circadian rhythms 00:51:20 - Time-restricted eating strengthens circadian biology 01:02:13 - Dr. Panda’s ongoing study uses a smartphone app to track diet 01:03:41 - Most people are unaware of their eating patterns 01:07:58 - How Dr. Panda incorporates his research findings into his own life 01:16:21 - Our circadian rhythms dictate when we should exercise If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/satchin-panda-3 Join over 300,000 people and get the latest distilled information on circadian insights straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor
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#064 Dr. Michael Snyder on Continuous Glucose Monitoring and Deep Profiling for Personalized Medicine
2021/05/27
Michael Snyder Dr. Michael Snyder is the director for the Center for Genomics and Personalized Medicine at Stanford and a pioneer and advocate of "deep profiling." Deep profiling seeks to apply intelligent analysis to large data sets to yield specialized clinical insight, ranging from common consumer-grade wearables like Apple Watches to whole-body MRI, continuous glucose monitoring, and metabolomics. In this episode, we discuss: 00:00:00 - Introduction 00:12:51 - Continuous glucose monitor use in people without diabetes 00:31:04 - A smartwatch helped diagnose Dr. Snyder's Lyme disease 00:34:00 - Predicting other illnesses with smartwatches 00:40:41 - Detecting airborne pollutants in the exosome  00:51:04 - Genetics and metabolism tell us our Ageotypes 00:58:05 - Exercise is most important for longevity 01:03:11 - Dr. Snyder's lifestyle habits If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/michael-snyder Join over 300,000 people and get the latest distilled information on personalized medicine straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor
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Podcast Reviews

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4.8 out of 5
4729 reviews
grantegginton 2022/05/29
Awesome podcasts
Rhonda’s podcast are awesome! She takes what are very complex scientific topics and turns them into everyday conversations for the average person. Gre...
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glennfoster 2022/06/06
Great interviews but…
Terrible sound quality. Most listening takes place in the car and the volume levels during some recordings varies from barely audible to distorting th...
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jacipurpleJOY 2022/05/16
Sauna
Loved all the detailed info on sauna use! Excited to get mine going. Thank you!
Papa Esteban 2022/04/20
Superb show
This show has helped me to grow into a healthier person.
Arlie K 2022/03/11
So glad I found this show!
Rhonda and her incredibly knowledgeable guests offer excellent information around the latest science on all things health and exercise. She is intelli...
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ersmed 2022/02/02
A fantastic LONGEVITY, Healthy Living podcast,
A must Podcast to have in your rotation if longevity and healthy living are important to you. Always research based and constantly interviewing the to...
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AllisonMarie123 2021/12/17
Great information
I appreciate the seemingly unbiased content this podcast provides. Thank you Dr. Patrick!
@qrioart 2021/11/05
Progressive Science and Spirit
You are clearly a facts-based awesome fountain of knowledge and I respect all of your work - I believe the world requires scientists like you along wi...
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Housewives Nit 2021/11/14
Meh
I loved her on Joe Rogan’s podcast because he could facilitate/navigate the conversation for the listeners who are not academic, to put a nice bow on ...
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Coach Tracy Wait 2021/11/11
Credibility
The Covid-19 episode is not going to age well. What was advertised to be an open minded and non-biased look at Covid 19 and treatments, is anything bu...
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