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At the 19th World Congress of the Societies of Anaesthesiologists (WCSA 2026) in Marrakesh, TopMedTalk welcomes Desiree Chappell back alongside Kate Leslie to interview Professor Palesa Motshabi-Chakane, Associate Professor and Head of Anaesthesiology at the University of the Witwatersrand and her colleague, Dr Mullai Slave a PhD candidate at University of the Witwatersrand. They discuss a study of 629 women undergoing cesarean section with spinal anesthesia at Chris Hani Baragwanath Hospital, where 23–33% are HIV positive. Using standard monitoring plus Edwards/BD noninvasive continuous hemodynamic monitoring, they compared HIV-positive and HIV-negative patients and found higher hypotension incidence in HIV-positive women (68% vs 64%), with lower heart rate and lower cardiac index over 60 minutes. Additional testing included echocardiography with speckle tracking, pro-BNP, and autonomic assessments, with HIV-positive patients showing stiffer ventricles; Apgar scores did not differ. They discuss replication, multicenter research, and potential machine-learning tools to predict hypotension risk, and describe BD grant support enabling equipment, sensors, staffing, and training (~200 staff) to complete data collection in about six months. Desiree Chappell, former Co Editor in Chief of TopMedTalk, is now Director, Medical Science Liaison, Medical Affairs, BD Advanced Patient Monitoring. The views expressed on this program are her own and not those of her employers.  We mention Adrian Gelb, if you'd like to hear his recent conversation with us go here: https://topmedtalk.libsyn.com/professor-adrian-gelb-on-patient-safety-and-essential-medicines-in-anaesthesia -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/  

Live from the 19th World Congress of Anaesthesiologists (WCA 2026) in Marrakesh with over 4,000 delegates from 150 countries, TopMedTalk's Kate Leslie and Mike Grocott interview Professor Adrian Gelb, past World Federation of the Societies of Anaesthesiologists (WFSA) president, about his career from South Africa to Canada and UCSF and his focus on lower-resource settings, patient safety, and WHO engagement. Gelb argues patient safety improvements require system and workflow changes, not just guidelines. The comparison is drawn to road safety reforms and urging anesthesiologists to use their leverage in hospitals and governance. He reflects on the impact of Harvard monitoring standards and leadership that advanced safety, and calls for national societies to prioritize patient-centered advocacy and implementation support using human factors and knowledge translation expertise. He also describes work on WHO essential medicines lists and proposes a tiered, anesthesia-led WFSA essential medicines list by country income level via a global Delphi process, ending with a call for anesthesiologists to choose to lead again. More about the congress here: https://wcacongress.org/ -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

Our coverage of the World Federation of Societies of Anaesthesiologists annual conference begins with an exclusive conversation with this year's recipients of the WFSA Blood Health Innovation Award, Vijay Anand Ismavel and Ann Miriam Devarathnam. Andy Cumpstey finds out about their collaborative project with Kerala Digital University to develop an intraoperative auto-transfusion device, designed to recycle a patient's own blood during surgery in resource-constrained environments. For more information about this device, see: https://jogs.one/icigs_1003_70/ -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

This piece sees the launch of a new series on TopMedTalk: we're delving further into the world of Artificial Intelligence in healthcare and we're going to do so at least once a month. Coming from the Association of Anaesthetists in London, Andy Cumpstey welcomes back former TopMedTalk Co-editor in Chief, Desiree Chappell, alongside editor-in-chief Professor Mike Grocott and Associate Professor James Bowness, Consultant in Anaesthesia at University College Hospitals London NHS Foundation Trust and Honorary Associate Professor of Anaesthesia at University College London and clinical scientist with G.E. Healthcare. As well as announcing the new series, featuring monthly AI-focused episodes with clinicians, policymakers, industry, and patient representatives. Specially recorded at the third stage of a UK and Ireland "demand signaling" exercise for AI in anesthesia, perioperative medicine, and pain management. It's a process designed to focus on clinicians' real-world needs rather than forcing unwanted technology use cases. The process includes surveying Royal College of Anaesthetists and Association members. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/  

Part two of our retrospective on TopMedTalk's coverage of last year's fascinating ANESTHESIOLOGY® 2025 in San Antonio, Texas, USA. This is part two of a two part piece. Part 1 is here: https://topmedtalk.libsyn.com/anesthesiology-2025-digest-part-1 This podcast contains clips and discussion from the following podcasts in our free archive: Exciting news from Desiree Chappell https://topmedtalk.libsyn.com/exciting-news-from-desiree-chappell Innovations in Anesthesia: GE Healthcare's Advanced Solutions at ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/innovations-in-anesthesia-ge-healthcares-advanced-solutions-at-anesthesiology-2025 Exploring the Future of Perioperative Care: Insights from ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/exploring-the-future-of-perioperative-care-insights-from-anesthesiology-2025 Perioperative Profile, Steven Shafer https://topmedtalk.libsyn.com/perioperative-profile-steven-shafer Optimizing Pediatric Blood Health: Insights from ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/optimizing-pediatric-blood-health-insights-from-anesthesiology-2025 Exploring Viscoelastic Testing and Patient Blood Management at ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/exploring-viscoelastic-testing-and-patient-blood-management-at-anesthesiology-2025 Insights from ANESTHESIOLOGY® 2025: Enhancing Research and Publishing in Obstetric Anesthesia https://topmedtalk.libsyn.com/insights-from-anesthesiology-2025-enhancing-research-and-publishing-in-obstetric-anesthesia Understanding Medical Errors: Cognitive Basis and Systemic Solutions at ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/understanding-medical-errors-cognitive-basis-and-systemic-solutions-at-anesthesiology-2025 Insights from ANESTHESIOLOGY® 2025: Surgical Site Infections, Oxygen Therapy, and Thermoregulation https://topmedtalk.libsyn.com/insights-from-anesthesiology-2025-surgical-site-infections-oxygen-therapy-and-thermoregulation Advancing Patient-Centered Monitoring Outcomes ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/advancing-patient-centered-monitoring-outcomes-anesthesiology-2025 Adrian Gelb on Neuroanesthesia, Global Patient Safety, and WFSA-WHO International Standards https://topmedtalk.libsyn.com/adrian-gelb-on-neuroanesthesia-global-patient-safety-and-wfsa-who-international-standards -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

A look back on the TopMedTalk coverage of last year's incredible ANESTHESIOLOGY® 2025 in San Antonio, Texas, USA. This is part one of a two part piece. Featuring clips and discussion from the following podcasts: Pediatric Airway Management Advances: Insights from Annery Garcia-Marcinkiewicz https://topmedtalk.libsyn.com/pediatric-airway-management-advances-insights-from-annery-garcia-marcinkiewicz The Center for Anesthesia Workforce Studies at ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/the-center-for-anesthesia-workforce-studies-at-the-asa-2025 Understanding Anesthesia Information Management Systems with Dr. David Kennedy https://topmedtalk.libsyn.com/understanding-anesthesia-information-management-systems-with-dr-david-kennedy Transforming Pain Medicine: An Insight into the Pain Medicine Coalition https://topmedtalk.libsyn.com/transforming-pain-medicine-an-insight-into-the-pain-medicine-coalition Clinical Readiness and Training Affiliation in Army Anesthesiology https://topmedtalk.libsyn.com/clinical-readiness-and-training-affiliation-in-army-anesthesiology Navigating Governance in Anesthesiology Groups: Insights from ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/navigating-governance-in-anesthesiology-groups-insights-from-asa-2025 Anesthesiology Economics: Current Trends and Future Directions https://topmedtalk.libsyn.com/anesthesiology-economics-current-trends-and-future-directions Insights on the Future of Anesthesia Quality Improvement with AQI https://topmedtalk.libsyn.com/insights-on-the-future-of-anesthesia-quality-improvement-with-aqi Insights from ANESTHESIOLOGY® 2025: New Guidelines for Anesthesiology in Older Adults https://topmedtalk.libsyn.com/insights-from-anesthesiology-2025-new-guidelines-for-anesthesiology-in-older-adults Nitrous Oxide as a Treatment for Severe Depression: Insights from ANESTHESIOLOGY® 2025 https://topmedtalk.libsyn.com/nitrous-oxide-as-a-treatment-for-severe-depression-insights-from-anesthesiology-2025 -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

TopMedTalk is proud to present Perioperative Profiles. This month we speak with Rupert Pearse, OBE, professor of intensive care medicine at Queen Mary University of London and a consultant at Royal London Hospital, known for his research on improving outcomes in high-risk surgical patients. In this fascinating piece we speak about his career in perioperative and critical care medicine. Raised in rural Bedfordshire as a farmer's son, he switched late from plans to study agriculture to medicine, took a year out working as an auxiliary nurse and carer, and entered St George's, London, where an intercalated BSc introduced him to research. He reflects on receiving an OBE, and outlines future priorities: growing his East London research group, global health collaborations, leadership, mentorship, and health equity.   Like this? You may enjoy our interview with Bruce Biccard from 2024: https://topmedtalk.libsyn.com/talks-to-bruce-biccard-tmt-in-prato -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

TopMedTalk are proud to present The Siobhan Mythen Plenary Lecture, taken from our coverage of Evidence Based Perioperative Medicine (EBPOM) Ireland 2025. Professor Ellen O'Sullivan trained in anaesthesiology and intensive care in UK and USA and is now a Consultant Anaesthesiologist at St James's Hospital Dublin, Ireland, affiliated to Trinity College Dublin. She specializes in airway management and is Director of the Fellowship in Advanced Airway Management and Simulation. She is Past President of the Difficult Airway Society, DAS, and was appointed DAS Professor of Anaesthesia & Airway Management. She outlines the "The difficult anatomical airway" and introduces the Siobhan Mythen plenary lecturer Professor John Laffey. John Laffey is Professor of Anaesthesia and Intensive Care Medicine at the University of Galway (formerly National University of Ireland, Galway), where he also serves in clinical and research leadership roles. His work focuses on critical illnesses, particularly Acute Respiratory Distress Syndrome (ARDS), sepsis, mechanical ventilation strategies, and translational research including cell/gene therapies for these conditions. He discusses, "The Difficult Physiology Airway" -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

At the Royal College of Anaesthetists' Centre for Perioperative Care (CPOC) Perioperative Leads Day in London, host Andy Cumpstey speaks with James White, a perioperative medicine clinician (and qualified general practitioner) working within the NHS in Cheshire and Merseyside, serving as Clinical Lead for Perioperative Medicine and contributing to national improvement work with the Centre for Perioperative Care, Simon Rang, consultant anaesthetist at East Kent Hospitals University NHS Trust who also contributes to national healthcare improvement work including with the Centre for Perioperative Care, and Denny Levett, Director of the Centre for Perioperative Care, and a Professor of Perioperative Medicine and Critical Care and Consultant at University Hospital Southampton NHS Foundation Trust and the University of Southampton. The conversation covers how UK perioperative medicine policy is implemented through evolving NHS structures. They explain the relationship between national policy (Department of Health, NHS England) and delivery via regions, integrated care boards (ICBs), and local trusts, emphasizing integrated pathways spanning primary and secondary care, particularly post-COVID. James outlines five core requirements: early perioperative screening, proactive optimization/prehabilitation, maintaining health while waiting, listing patients only when medically fit, and shared decision-making. The guests discuss how regional and ICB networks share solutions, address variation and barriers (including finances and culture), and use CPOC guidance and resources alongside initiatives like GIRFT to support consistent implementation. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

At the ANESTHESIOLOGY® 2025 meeting in San Antonio, TopMedTalk hosts Andy Cumpstey and Kate Leslie interviewed Professor of Anesthesia and Perioperative Care at University of California, San Francisco, Adrian Gelb, this year's Ellison Pierce Lecturer. Dr Gelb recounts training in South Africa, work in England and Canada, and how he was steered into neuroanesthesia at a high-volume cerebral aneurysm center, becoming engaged by understanding surgical outcomes and encouraging trainees to learn the operative field. He describes developing global health interests, joining the World Federation of Societies of Anaesthesiologists (WFSA) through Alan Merry and others, and progressing from the patient safety committee to WFSA president. Gelb outlines updating WFSA standards with WHO involvement, emphasizing additive "minimum" requirements (e.g., oxygenation and pulse oximetry) and clarifying differences among policies, guidelines, and legally binding standards, urging implementation-focused sequencing. He also highlights AI's potential to advance decision-making, documentation, data, and feedback. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

Andy Cumpstey is joined by Christian Macutkiewicz Consultant General, HPB and Hernia Surgeon at Manchester Royal Infirmary, Director of The Gallstone Clinic and Manchester Hernia at Spire Manchester Hospital and the incoming President of the Association of Surgeons of Great Britain and Ireland, and Dimitris Damaskos Consultant General Surgeon within the Department of Surgery at the Royal Infirmary of Edinburgh (NHS Lothian), Honorary Clinical Senior Lecturer at the University of Edinburgh. They discuss the postoperative period as a critical part of the perioperative journey, emphasizing the importance of clear postoperative communication, reassurance even after "successful" operations, and explaining complications and expected recovery timelines. They highlight challenges in recognizing deterioration, including reduced reliance on clinical examination skills among junior doctors and the systems-based concept of "failure to rescue," arguing that consistent ward-based recognition systems and high-volume units help detect complications earlier. Enhanced Recovery After Surgery (ERAS) pathways are cited, including using day-3 CRP thresholds to trigger CT imaging for early detection of anastomotic leak. They note post-COVID pressures to clear surgical backlogs have increased situations where patients are operated on by surgeons who did not initially see them, potentially weakening trust and continuity when complications occur, and they discuss flattening hierarchy so trainees can do ward rounds with consultant support. The conversation covers future technology, including AI for risk stratification and imaging interpretation, and remote continuous vital-sign monitoring, while acknowledging data governance challenges and potential deskilling. The episode closes with a discussion of robotic surgery: improved optics and precision and usefulness for more complex cases (including abdominal wall reconstruction), but with concerns about cost, rollout, training implications, and differing adoption between the UK, US, and New Zealand. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

In this episode of TopMedTalk, hosted by Andy Cumpstey at the anaesthesia research meeting in Birmingham, we dive into drug allergy and its mislabeling with Louise Savic, consultant anaesthetist and NIHR doctoral researcher at Leeds Teaching Hospitals NHS Trust, UK, who specialises in drug allergy and peri-operative anaphylaxis, and Tom Abbott, clinical senior lecturer in anaesthesia and peri-operative medicine at Queen Mary University of London, UK, and a consultant anaesthetist whose research uses clinical epidemiology and trials to improve surgical outcomes and reduce peri-operative complications. The discussion highlights the vast disparity between true drug allergies and mislabeling, emphasizing that around 90-95% of penicillin allergy labels are incorrect. Dr. Savic shares her journey in drug allergy research, focusing on the perioperative setting, while Dr. Abbott discusses the linkage between antimicrobial prescribing and resistance. The talk covers results from the Sapphire Project, revealing the high incidence of mislabeled drug allergies and their associated increased postoperative risks. The episode also explores potential strategies for 'de-labeling' patients, the role of multidisciplinary collaboration, and the next steps in research and practice change. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

Andy Cumpstey welcomes Joseph Alderman, a clinical lecturer in anaesthesia at the University of Birmingham, to discuss the hurdles AI faces in the healthcare sector. Dr. Alderman, who has a background in cell biology and immunometabolism, shares his insights into why AI technologies often fail to reach patients. He identifies three primary challenges: misalignment between AI development and healthcare needs, inadequate resourcing, and premature solution-oriented thinking. The conversation also touches on the importance of involving patients and clinicians in the AI development process and an exciting new initiative by Dr. Alderman's team to create a health chatbot user guide. The episode concludes with a look into regulatory challenges and the need for better patient empowerment and risk management in AI-driven healthcare. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

Michelle Chew is a Professor of Anesthesiology and Intensive Care Medicine at Karolinska Institutet, Stockholm, Sweden, and editor for the British Journal of Anaesthesia. Hear her sharing her Perioperative Profile on TopMedTalk with Andy Cumpstey. After initial anaesthesia training in Denmark, she moved to Lund University, Sweden, combining clinical work and research, later establishing her own experimental haemodynamics group studying septic and haemorrhagic shock and myocardial changes. She balances academic and family life by prioritizing rather than seeking "life balance," noting challenges for women in academia despite Scandinavian support. She explains journal editing—from rapid assessment, literature checks, peer review coordination, to feedback synthesis—and entered the field via the European Journal of Anaesthesiology, later serving at BJA and other journals. She also describes developing clinical guidelines, emphasizing expert panels, systematic reviews, consensus, and local adaptation, with involvement in Scandinavian and European anesthesia societies. Throughout, she highlights lessons from mentors and family, especially her grandmother, stresses taking opportunities and putting in the work, and emphasizes that science and clinical medicine ultimately serve patients. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

ANESTHESIOLOGY® 2025, the annual meeting of the American Society of Anesthesiologists (ASA), and Desiree Chappell hosts Professor Michael Scott from the University of Rochester and Dr Wael Saasouh, director of research for NorthStar Anesthesia. The discussion centers on the evolution of patient-centered monitoring, the importance of continuous hemodynamic monitoring, and the broader implications of hemodynamic instability. The guests delve into their recent consensus paper with the Anesthesia Patient Safety Foundation and highlight the need for more comprehensive monitoring technologies that are accessible and cost-effective. The conversation also explores international collaborations, differences in practice settings (academic vs. private), and the future of enhanced recovery and post-operative care. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/