
Advertise on podcast: pureANIMAL Collective
Rating
3.7from
This podcast has
95 episodes
Language
EnglishPublisher
pureANIMAL CollectiveExplicit
No
Date created
2018/11/29
Latest episode
2026/10/06
Average duration
53 min.
Release period
31 days
Description
The Pure Animal Podcast shares cutting edge science, clinical wisdom, and inspiration on integrative veterinary medicine. Each month, we interview industry experts who explore the fields of joint health, dermatology, internal medicine, integrative and functional medicine and allied health modalities. Our mission is to create a world where integrative veterinary medicine is accessible to all, to empower and inspire other veterinary professionals and pet parents alike, and to ultimately improve the health and wellbeing of pets. Host Dr Sarah Howard is a veterinarian and lifelong student of natural health.
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Check latest episodes from pureANIMAL Collective podcast
Rethinking Omega 3 fatty acids with Dr Nicole Rous
2026/10/06
This month Dr Sarah Howard discusses Omega-3 fatty acids with our ambassador Dr Nicole Rous.
Topics discussed include:
What is there to re-think about Omega-3s? Components, quality and formulation of Omega-3's What about Omega-6? Is it really pro or anti-inflammatory? How sources and formulations of Omega-3's change the conversion efficiency of EPA/DHA depending on dietary format. Does added Omega-6 improve or hinder conversion? What influence does fatty acids have on the body, and when is it indicated? How to measure Omega-3's - what is the optimal Omega-3 index range? What is red blood cell fatty data? What is the best ratio for dietary Omega-3:6? How do they compete for absorption? How to set a base line for each patient, including interval timeline for tracking supplementation Where human medicine literature fits vs veterinary medicine Should we be proactive or reactive when implementing Omega-3 strategies? EPA/DHA ratios - how to maximise therapeutic benefits What Omega-3 research is still missing Sign up to the pureANIMAL eDM here:
https://forms.office.com/Pages/ResponsePage.aspx?id=lMwqDE_nw0GpT3Rwh45wwTpamnXk-KNLocqVxzPS4LpURTlIVzA5RURKRDlJRjRaWlE0TVZHOFNSMy4u
This episode was brought to you by PAW, Pure Animal Wellbeing - developed by vets, inspired by nature and dedicated to supporting lifelong health in pets. PAW | Pure Animal Wellbeing
See omnystudio.com/listener for privacy information.
A functional approach to managing osteoarthritis in pets with Dr Matthew Muir
2026/09/01
In this episode, Dr Sarah Howard discusses a functional approach to managing osteoarthritis with Dr Matthew Muir.
Topics discussed include:
Osteoarthritis is not just wear and tear - Dr Muir explains what actually happens during this condition. How does functional medicine complement conventional osteoarthritic care? Addressing cartilage degeneration with nutrition and nutraceuticals. Matthew discusses how he decides what to target first in osteoarthritic cases. The role nutraceuticals play in managing osteoarthritis and combining them with other modalities. Dr Muir's preferred joint supplements, their mechanism of action and the additional benefits they can provide. Therapies that are useful in conjunction with supplements and pharmaceuticals. Deescalating a management plan - the reason for this and what treatment to remove first. Escalating a management plan with the addition of pharmaceuticals - Dr Matt describes the best time to do this. Sign up to the pureANIMAL eDM here:
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This episode was brought to you by PAW, Pure Animal Wellbeing - developed by vets, inspired by nature and dedicated to supporting lifelong health in pets. PAW | Pure Animal Wellbeing
See omnystudio.com/listener for privacy information.
The use of antibiotics during the critical developmental window with Professor Caroline Mansfield
2026/08/04
In this episode with Professor Caroline Mansfield, we discuss the use of antibiotics during the critical developmental window of puppies and kittens and the impact in long term risk of skin allergic disease and behaviour.
Topics discussed include:
What is the critical developmental window and what body systems it can affect and impact? The link between the microbiome and its role in shaping the immune system in puppies and kittens. Evidence in the use of antibiotics early in life in children and how it can affect the incidence of asthma and allergic skin disease. The impact of metronidazole and how it can alter the microbiome. Professor Caroline discusses a study linking antibiotic use and atopic dermatitis and behavioural issues in dogs. Professor Mansfield gives her expert advice to pet parents on how to support the immune and gastrointestinal systems during their pet's developmental window. Clarifying the misconceptions on antibiotics, allergic and immune mediated disease. What is the latest research in this area of the critical developmental window and the impact of antibiotics? Sign up to the pureANIMAL eDM here:
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This episode was brought to you by PAW, Pure Animal Wellbeing - developed by vets, inspired by nature and dedicated to supporting lifelong health in pets. PAW | Pure Animal Wellbeing
See omnystudio.com/listener for privacy information.
Dermatology with veterinary nurse Karin Murik
2026/06/30
Karin Murik is a Registered Veterinary Nurse at Animal Dermatology Clinic in Perth, WesternAustralia, a specialist referral clinic dedicated to the diagnosis and treatment of complex skin, allergy and ear diseases in dogs, cats and horses. Originally from Estonia, Karin graduated in 2016 and has worked across a range of veterinary disciplines including general practice, dermatology, cardiology, emergency and oncology nursing. She has a particular passion for allergies and allergen-specific immunotherapy, with extensive involvement in allergy testing, immunotherapy preparation, patient care and client education. Karin is committed to helping pet owners better understand and manage chronic skin disease, improving both patient comfort and long-term treatment success. She is also actively involved in veterinary communication and education through social media and client outreach initiatives.
Topics discussed include:
What drew Karin to become a veterinary dermatology nurse. The role of a dermatology nurse at dermatology clinics. Karin shares what nursing skills are most important when dealing with dermatology cases. The importance of supporting pet parents in managing treatment plans for their pets and ensuring compliance. The procedures that veterinary dermatology nurses responsible for. Karin dives into all aspects of immunotherapy. What is the biggest difference that pet parents can make at home when caring for their allergic pets. Karin gives her advice on what nurses can do to pursue a career with a dermatology focus.
Sign up to the pureANIMAL eDM here:
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For more information on the Animal Dermatology Clinic visit their website: https://www.animaldermatologyclinic.com.au/
This episode was brought to you by PAW, Pure Animal Wellbeing - developed by vets, inspired by nature and dedicated to supporting lifelong health in pets. PAW | Pure Animal Wellbeing
See omnystudio.com/listener for privacy information.
Managing inflammation and titre testing with Dr Nicole Rous
2026/06/02
In this episode, we welcome back Dr Nicole Rous for her first 2026 podcast discussing inflammation and titre testing.
Topics discussed include:
· The shift towards personalised care beyond routine care through collaborative approach · Understanding and managing the inflammatory load · Multifactorial contribution to inflammation: genetics, diet, environment and modern lifestyle · The gut mucosa and the impact of “leaky gut” triggering the overreaction of the immune system · Food intolerances due to poor gut resilience often mislabeled as allergies · The choice between routine vaccine versus titre test · 2024 WSAVA vaccination guideline recognises titre testing as a method for protection monitoring · Titre test options: in-house or commercial laboratory analysis · Titre testing for pets with co-morbidities and those with previous adverse reaction to vaccines · Strategic approach to parasite prevention through screening · Resistance risks associated with routine anthelmintic use This episode was brought to you by PAW, Pure Animal Wellbeing - developed by vets, inspired by nature and dedicated to supporting lifelong health in pets. PAW | Pure Animal Wellbeing
Sign up to the pureANIMAL eDM here:
https://forms.office.com/Pages/ResponsePage.aspx?id=lMwqDE_nw0GpT3Rwh45wwTpamnXk-KNLocqVxzPS4LpURTlIVzA5RURKRDlJRjRaWlE0TVZHOFNSMy4u
See omnystudio.com/listener for privacy information.
Everything acupuncture and joint health with Dr Alison Shen
2026/05/05
In this month's episode, we welcome veterinarian Dr Alison Shen to discuss everything acupuncture and joint health.
Dr Alison Shen has a keen interest in acupuncture and traditional Chinese medicine, embracing a holistic approach to animal health and wellbeing. She completed her Certificate in Veterinary Acupuncture through the International Veterinary Acupuncture Society in 2008 and has also earned a Certificate in Clinical Integrative Canine Rehabilitation from the College of Integrative Veterinary Therapies. Dr Shen practices in Brisbane and travels to Sydney, once a month as part of her business, The Acupuncture Vet.
She also runs the popular Future Vet Kids Camp in various locations in Australia and they are both part of the team of veterinarians on the TV show – Bondi Vet.
Topics discussed include:
Dr Alison's journey to becoming a veterinary acupuncturist. The most common reason pet owners seek acupuncture treatment for their animals. How does acupuncture work to reduce pain and inflammation? What happens during a typical consultation with Dr Shen? The frequency of treatment most patients require. How early can pain reduction be noticed and what to expect after treatment? Tools and techniques that pet parents can use at home to continue with their pet's management. What modalities does Dr Alison offer to her patients and for which cases? Dr Alison explains the difference between acupuncture and electroacupuncture. How can veterinarians get certified in veterinary acupuncture? Dr Alison's takeaway from today's episode.
Acupuncture certification courses:
International Veterinary Acupuncture Society
Home | College of Integrative Veterinary Therapies
Veterinary Acupuncture - Chi University
This episode was brought to you by PAW, Pure Animal Wellbeing - developed by vets, inspired by nature and dedicated to supporting lifelong health in pets. PAW | Pure Animal Wellbeing
Sign up to the pureANIMAL eDM here:
https://forms.office.com/Pages/ResponsePage.aspx?id=lMwqDE_nw0GpT3Rwh45wwTpamnXk-KNLocqVxzPS4LpURTlIVzA5RURKRDlJRjRaWlE0TVZHOFNSMy4u
See omnystudio.com/listener for privacy information.
Feline nutrition, microbiome and chronic disease with Dr Matthew Muir
2026/03/31
We welcome back Dr Matthew Muir with a masterclass on functional veterinary medicine looking specifically at feline nutrition. microbiome and chronic disease.
Topics discussed include:
How do we start providing better care to cats, especially with regards to their diet? All diseases start in the gut, is this also true for cats? In nature, what would cats self-select to eat and how does that compare to commercial diets? Feeding management vs diet composition and their impact on diabetes mellitus. The impact of low protein diets on cats. What macronutrient ratio should we be aiming for in a cat's diet? How do diet needs change from kittens to senior cats? The role ultra-processed foods play in chronic disease. Can diets help manage chronic enteropathies? The importance of hydration in cats and does it change depending on their diets? How does nutrition impact mental health disorders in cats? What does a functional preventative protocol look like for a general practitioner?
Sign up to the pureANIMAL eDM here:
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Dr Matt's resources:
https://icatcare.org/resources/five-a-day_felix_full_report.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC6390407/
https://vetmed.illinois.edu/wp-content/uploads/2021/12/How-to-Make-the-Trip-to-the-Vet-Hospital-Fear-Free_EDITED.pdf
https://catinfo.org/
See omnystudio.com/listener for privacy information.
Episode Encore - Caroline Moeser talks about probiotics in practice
2026/03/03
In this episode encore, Dr Sarah Howard talks to Dr Caroline Moeser about probiotics in practice.
Topics include:
How Caroline became a vet and ended up at Guide Dogs Australia Caroline’s main interests in Veterinary medicine Dr Moeser talks about how probiotics can shape the gut microbiome and how they have helped the dogs at Guide Dogs Australia How probiotics has helped reduce the incidence of diarrhoea at Guide Dogs When is the right time to introduce the dams and pups to probiotics? Can probiotics help with allergic skin disease? The link between a healthy microbiome and development of behavioural conditions Besides prebiotics and probiotics, Caroline talks about other things that can help to keep a healthy microbiome Dr Moeser discusses faecal transplants in dogs, its indications and benefits Microbiome analysis in dogs See omnystudio.com/listener for privacy information.
Episode Encore - PEA and allergic skin disease with Dr Meng Siak
2026/02/03
In this episode encore, Dr Meng Siak talks about PEA and allergic skin disease. Topics discussed include:
Dr Meng discusses what PEA is and how it works. How does PEA relate to the endocannabinoid system? The properties of PEA and where they act within the body. Meng goes over the literature that is available for PEA. What dermatology cases would PEA be beneficial for? Dr Siak discusses whether PEA can reduce the requirement for pharmaceuticals. What side effects can be expected with the use of PEA? Safety of PEA and interactions with other drugs. Dr Meng shares his practical advice on how to use PEA. This was a podcast re-play, and the webinar link is no longer available.
See omnystudio.com/listener for privacy information.
How to create a calm clinic environment with vet nurse Jacinta Van Eeden
2026/01/06
In this month's episode we welcome our first vet nurse guest, Jacinta Van Eeden to discuss the changes that can be implemented to create a calm veterinary clinic environment.
Topics discussed include:
The importance of a calm clinic environment. Common signs that indicate a pet may be anxious or stressed. Ways to get puppies and kittens used to visiting vet clinics. How our tone of voice can impact a pet's behaviour. Practical tools that clinics can implement to provide a relaxing environment. Steps that pet parents can take to prepare their pets for clinics visits. Fear free certification for veterinary clinics. Jacinta shares how to reduce anxiety in pet parents when their pet has a vet consultation. The number on tip Jacinta has for pet parents to ensure their pet doesn't become anxious when visiting vet clinics. See omnystudio.com/listener for privacy information.
Functional approach to managing allergic dermatitis with Dr Matthew Muir
2025/12/02
In this episode, Dr Sarah Howard speaks to Dr Matthew Muir on his functional approach to managing allergic dermatitis.
Topics discussed include:
Dr Matthew Muir's approach to pets with allergic dermatitis The reason immunotherapy is so under-utilised and its limitations. Conventional allergy management pharmaceuticals and how they work. How diet plays a role in Dr Muir's functional approach (immuno-nutrition). The relationship between the microbiome and allergies. The nutraceuticals Matthew might use when managing a dermatology case. How can we manage acute cases outside of a pharmaceutical approach? Dr Matthew discusses what is new and emerging in this field. What can pet owners do to decrease the risk of skin allergies in dogs? See omnystudio.com/listener for privacy information.
Setting your puppy up for success with Dr Nicole Rous
2025/11/04
In this episode Dr Nicole Rous breaks down the process of bringing a puppy home and providing the optimal environment for physical and behavioral development.
Topics discussed include:
Tips on selecting the right puppy from a breeder, shelter or pet shop. The benefits of finding a good breeder and maintaining a good relationship. How to get a good idea of the innate temperament of the parents. Puppy socialisation timeline and the value of positive socialisation. How the breed compatibility with the owner lifestyles matters to the development of the puppy. Dr Rous discusses how we should approach to puppy behavioural training and the common mistakes we make. Positive reinforcement training and understanding how to read behavioural signals. Common mistakes that pet parents make. Importance of the vet role in the fear free experience. Nutrition needs for puppies, the benefits to their trainability and the optimal puppy diet. Dr Rous describes the considerations behind choosing a good chew for puppies. Desexing considerations. To listen to Dr Rous' podcast on desexing, go to this link https://omny.fm/shows/pure-animal-podcast/neutering-insights-with-dr-nicole-rous
To register to Dr Matthew Muir's dermatology webinar, go to this link https://my.demio.com/ref/w0mUrHThNOb0WpKe
See omnystudio.com/listener for privacy information.
Nutrient-based psychiatry with Dr Matthew Muir
2025/09/30
In this month's episode, Dr Sarah Howard discusses nutrient based psychiatry in the veterinary field with Dr Matthew Muir.
Topics discussed include:
Dr Muir explains what nutrient-based psychiatry is. How does Matthew apply nutrient based psychiatry in the veterinary field? What research is available supporting the importance that nutrition and microbiome diversity has on behaviour in dogs? What nutrients are missing from some commercial diets? How important is diet diversity? Ingredients present in diets that can be detrimental to dogs. Choosing the correct nutritional diet for your pet. Dr Muir's number one advice for veterinarians when it comes to nutrition and behaviour. See omnystudio.com/listener for privacy information.
Urolithiasis and the microbiome with Professor Caroline Mansfield
2025/09/02
In this episode, we discuss with Professor Caroline Mansfield, urolithiasis in dogs and cats and their relationship with the microbiome.
Topics discussed included:
What are uroliths and how are they formed? The different types of uroliths and the risk factors for their development. The way in which the gut microbiome can influence the development of urinary crystals and stones. Can microbiome modification form part of urolith management? Links between development of urolith and gut disease. Is there a clear gut-kidney axis? Can dysbiosis contribute to kidney disease? Professor Caroline shares the management plan she uses for her urolith cases. Probiotics that could be helpful in urinary cases. See omnystudio.com/listener for privacy information.
Rethinking healthy ageing in dogs with Dr Matthew Muir
2025/08/05
In this episode Dr Sarah Howard discusses healthy ageing in dogs with Dr Matthew Muir.
Topics discussed include:
The reason ageing is currently a hot topic. What leads to an increased lifespan and better quality of life? Diet changes that can impact ageing in dogs. Dr Muir discusses what we should avoid in order to increase lifespan. Matthew goes into details of what dogs' diets should look like to prevent disease. How often should we be feeding our pets? What happens to the gut microbiome as dogs get older? Dr Muir delves into supplements that can be beneficial for ageing and emerging tools that are becoming available. The importance of preventative medicine - proactive vs reactive care. Accelerators of biological ageing. Additional resources:
https://pubmed.ncbi.nlm.nih.gov/11991408/ https://pmc.ncbi.nlm.nih.gov/articles/PMC11675035/https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1355560/full https://pmc.ncbi.nlm.nih.gov/articles/PMC11505706/ https://www.mdpi.com/1660-3397/18/11/564https://pmc.ncbi.nlm.nih.gov/articles/PMC4936929/ https://pubmed.ncbi.nlm.nih.gov/22216092/
Adams VJ, Watson P, Carmichael S, Gerry S, Penell J, Morgan DM. Exceptional longevity and potential determinants of successful ageing in a cohort of 39 Labrador retrievers: results of a prospective longitudinal study. Acta Vet Scand. 2016;58:29. doi:10.1186/s13028-016-0204-8 Cupp CJ, Jean-Philippe C, Kerr WW, Patil AR. Effect of nutritional interventions on longevity of senior cats. Int J Appl Res Vet Med. 2007;5(3):133–149 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Jackson J, Radford AD, Belshaw Z, Wallis LJ, Kubinyi E, German AJ, Westgarth C. Using veterinary health records at scale to investigate ageing dogs and their common issues in primary care. J Small Anim Pract. 2025;66(2):81–91. doi:10.1111/jsap.13809 Creevy KE, O'Neill DG, Promislow DEL. Morbidity and mortality in elderly dogs – a model for human aging. BMC Vet Res. 2022;18(1):456. doi:10.1186/s12917-022-03518-8 Lewis TW, Wiles BM, Llewellyn-Zaidi AM, Evans KM, O’Neill DG. Longevity and mortality in Kennel Club registered dog breeds in the UK in 2014. Canine Genet Epidemiol. 2018;5:10. doi:10.1186/s40575-018-0066-8 Kealy RD, Lawler DF, Ballam JM, Mantz SL, Biery DN, Greeley EH, Lust G, Segre M, Smith GK, Stowe HD. Effects of diet restriction on life span and age-related changes in dogs. J Am Vet Med Assoc. 2002;220(9):1315–1320. doi:10.2460/javma.2002.220.1315 Guelfi G, Capaccia C, Tedeschi M, Bufalari A, Leonardi L, Cenci-Goga B, Maranesi M. Dog aging: a comprehensive review of molecular, cellular, and physiological processes. Cells. 2024;13(24):2101. doi:10.3390/cells13242101 Laflamme DP. Nutritional care for aging cats and dogs. Vet Clin North Am Small Anim Pract. 2012;42(4):769–791. doi:10.1016/j.cvsm.2012.04.002 Hall JA, Jewell DE. Feeding healthy beagles medium-chain triglycerides, fish oil, and L-carnitine offsets age-related changes in serum fatty acids and carnitine metabolites. PLoS One. 2012;7(11):e49510. doi:10.1371/journal.pone.0049510 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Bray EE, Zheng Z, Tolbert MK, McCoy BM, Kaeberlein M, Kerr KF; Dog Aging Project Consortium. Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project. GeroScience. 2022;44(3):1779–1790. doi:10.1007/s11357-022-00575-7 Palaseweenun P, Hagen‐Plantinga EA, Schonewille JT, Koop G, Butre C, Jonathan M, Wierenga PA, Hendriks WH. Urinary excretion of advanced glycation end products in dogs and cats. J Anim Physiol Anim Nutr (Berl). 2021;105(1):149–156. doi:10.1111/jpn.13347 Yang L, Yang L, Cai Y, Luo Y, Wang H, Wang L, Chen J, Liu X, Wu Y, Qin Y, Wu Z, Liu N. Natural mycotoxin contamination in dog food: a review on toxicity and detoxification methods. Ecotoxicol Environ Saf. 2023;257:114948. doi:10.1016/j.ecoenv.2023.114948 Bridglalsingh S, Archer-Hartmann S, Azadi P, Barbier de La Serre C, Remillard RL, Sunvold GD, Bartges JW. Association of four differently processed diets with plasma and urine advanced glycation end products and serum soluble receptor for advanced glycation end products concentration in healthy dogs. J Anim Physiol Anim Nutr (Berl). 2024;108(3):735–751. doi:10.1111/jpn.13927 Marchi PH, Vendramini THA, Perini MP, Zafalon RVA, Amaral AR, Ochamotto VA, Da Silveira JC, Dagli MLZ, Brunetto MA. Obesity, inflammation, and cancer in dogs: review and perspectives. Front Vet Sci. 2022;9:1004122. doi:10.3389/fvets.2022.1004122 Schmid SM, Hoffman JM, Prescott J, Ernst H, Promislow DEL, Creevy KE; Dog Aging Project Consortium. The companion dog as a model for inflammaging: a cross-sectional pilot study. GeroScience. 2024;46(6):5395–5407. doi:10.1007/s11357-024-01217-w Ren J, Li H, Zeng G, Pang B, Wang Q, Wei J. Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time? Front Pharmacol. 2023;14:1178596. doi:10.3389/fphar.2023.1178596 Parker A, Romano S, Ansorge R, Aboelnour A, Le Gall G, Savva GM, Pontifex MG, Telatin A, Baker D, Jones E, Vauzour D, Rudder S, Blackshaw LA, Jeffery G, Carding SR. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome. 2022;10:68. doi:10.1186/s40168-022-01262-3 Ulluwishewa D, Anderson RC, McNabb WC, et al. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr. 2011;141(5):769–76. doi:10.3945/jn.110.135657 Cao L, Lee SG, Lim KT, Kim HR. Potential anti-aging substances derived from seaweeds. Mar Drugs. 2020;18(11):564. doi:10.3390/md18110564 Grzeczka A, Graczyk S, Kordowitzki P. Pleiotropic effects of resveratrol on aging-related cardiovascular diseases—what can we learn from research in dogs? Cells. 2024;13(20):1732. doi:10.3390/cells13201732 Kusaba A, Arai T. Shiitake mushroom powder supplementation increases antioxidative activity in dogs. Front Vet Sci. 2024;11:1355560. doi:10.3389/fvets.2024.1355560 Cho HW, Choi S, Seo K, Kim KH, Jeon JH, Kim CH, Lim S, Jeong S, Chun JL. Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus. J Anim Sci Technol. 2022 Sep;64(5):937-949. Kaur J, Seshadri S, Golla KH, Sampara P. Efficacy and safety of standardized ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial. J Vet Behav. 2022;51:8–15. Bharani KK, Devarasetti AK, Carey L, Khurana A, Kollipaka R, Hanuman DDV, Chetla VS, Banothu AK. Effects of ashwagandha (Withania somnifera) root extract on aging-related changes in healthy geriatric dogs: A randomized, double-blinded placebo-controlled study. Vet Med Sci. 2024 Sep;10(5):e1556 Sacoor C, Marugg JD, Lima NR, Empadinhas N, Montezinho L. Gut-brain axis impact on canine anxiety disorders: new challenges for behavioral veterinary medicine. Vet Med Int. 2024;2024:2856759. doi:10.1155/2024/2856759 Lee E, Carreras-Gallo N, Lopez L, Turner L, Lin A, Mendez TL, Went H, Tomusiak A, Verdin E, Corley M, Ndhlovu L, Smith R, Dwaraka VB. Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions. Aging (Albany NY). 2024;16(4):3088–3106. doi:10.18632/aging.205581 Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice. eLife. 2016;5:e16351. doi:10.7554/eLife.16351 Urfer SR, Kaeberlein TL, Mailheau S, Bergman PJ, Creevy KE, Promislow DEL, Kaeberlein M. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. GeroScience. 2017;39(2):117–127. doi:10.1007/s11357-017-9972-z Kaeberlein M, Creevy KE, Promislow DEL. The Dog Aging Project: translational geroscience in companion animals. Mamm Genome. 2016;27(7–8):279–288. doi:10.1007/s00335-016-9638- Mulder IE, Schmidt B, Lewis M, Delday M, Stokes CR, Bailey M, Aminov RI, Gill BP, Pluske JR, Mayer CD, Kelly D. Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity. PLoS One. 2011;6(12):e28279. doi:10.1371/journal.pone.0028279 Hemida M, Vuori KA, Moore R, Anturaniemi J, Hielm-Björkman A. Early life modifiable exposures and their association with owner-reported inflammatory bowel disease symptoms in adult dogs. Front Vet Sci. 2021;8:552350. doi:10.3389/fvets.2021.552350 McMahon JE, Graves JL, Tovar AP, Peloquin M, Greenwood K, Chen FL, Nelson M, McCandless EE, Halioua-Haubold CL, Juarez-Salinas D. Translational immune and metabolic markers of aging in dogs. Sci Rep. 2025;15:14460. doi:10.1038/s41598-025-51976-3 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Santos JDP, Cunha E, Nunes T, Tavares L, Oliveira M. Relation between periodontal disease and systemic diseases in dogs. Res Vet Sci. 2019;125:136–140. doi:10.1016/j.rvsc.2019.05.011 Selting KA, Ringold R, Husbands B, Pithua PO. Thymidine kinase type 1 and C-reactive protein concentrations in dogs with spontaneously occurring cancer. J Vet Intern Med. 2016;30(4):1159–1166. doi:10.1111/jvim.13954 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Clar
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