
Advertise on podcast: The Hunter Williams Podcast
Rating
4.6from
This podcast has
488 episodes
Language
EnglishPublisher
Hunter WilliamsExplicit
No
Date created
2020/04/09
Latest episode
2026/09/29
Average duration
80 min.
Release period
4 days
Description
Average health is a choice. And it's the wrong one. The Hunter Williams Podcast goes where mainstream medicine won't — deep into the science of peptides, hormone optimization, metabolic health, and biohacking protocols that actually move the needle. Every week, I sit down with elite researchers, doctors, and high-performers to cut through the noise and hand you biological leverage most people will never have access to. This isn't wellness. This is optimization. Subscribe. Take control of your biology.
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Check latest episodes from The Hunter Williams Podcast podcast
The Glutathione Masterclass | A Complete Research Guide (2026)
2026/09/29
Glutathione is the most boring compound I use. It's also one I'd put in my top five peptides.Your cells make it every day. It's your main internal antioxidant, the buffer that soaks up the damaging byproducts of making energy. Levels drop with age, alcohol, illness and hard training.
When that tank runs low, a lot of other therapies stop working as well.In this masterclass I break down redox in plain English. Then I cover who actually benefits and who can probably skip it. I walk through every delivery route and what the human data shows for each. Plain oral does a little. Liposomal does a lot more.I share my three dosing tiers, how I think about cycling, and why I keep injections away from the hours after training. We get into reconstitution, the taurine trick for injection sting, and storage. I also talk about the transdermal version I've been testing.
That one is anecdote only, with no controlled human data yet.Plus why I pair it with mitochondrial peptides, and why toxic burden may be behind a lot of stalled GLP-1 results.If your protocol has plateaued and you can't figure out why, start here.
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links
The ARA-290 Masterclass | A Complete Research Guide (2026)
2026/09/22
Most peptides get knocked for having no human trials.
ARA-290 is one of the few that does. Randomized, placebo-controlled studies show it regrowing small nerve fibers.In this masterclass I walk through where it came from. It was built out of EPO, the kidney hormone made famous by blood doping. The researchers kept the tissue repair side and left out the red blood cell side.
So no rise in hematocrit, which is how thick your blood runs, and no added clotting risk.I cover who this is for. Mainly diabetic neuropathy, small fiber neuropathy from sarcoidosis, and unexplained burning nerve pain.
I also cover who should skip it. If a herniated disc is pressing on a nerve, this won't decompress anything.Then we get practical. The 2017 trial found 4 mg a day beat both 1 mg and 8 mg. I go through cycling, week by week expectations, and why I'd run it before BPC-157 and TB-500. I explain why some vials gel up and how phosphate-buffered saline fixes it.The limits are in here too.
The longest trial ran twelve weeks. The long COVID use is anecdotal only.I don't use it myself. I don't have neuropathy. But if nerve pain is your problem, this one can be a godsend.
For research and entertainment purposes only. Subscribe for more peptide research and analysis.
👇 ALL MY LINKS IN ONE PLACE
https://hunterwilliamshealth.com/links
The Cartalax Masterclass | A Research Guide (2026)
2026/09/15
Most people have never heard of Cartalax. I think it's the peptide that gets healing done when BPC-157 and TB-500 stall out.This is the full masterclass. Cartalax is a three amino acid bioregulator from the Khavinson group in Russia. BPC and TB-500 work on growth factors at the cell surface. Cartalax goes inside the nucleus and changes which genes cartilage cells express. In cell culture it roughly doubled chondrocyte growth and raised SIRT1 and SIRT6, two longevity proteins that drop in arthritic joints. Human data is thin, so I'm clear about where the research ends and my experience begins.I cover why cartilage is so hard to heal, how Cartalax fits next to BPC, TB-500, GHK and KPV, my three dosing tiers from maintenance up to 2mg a day, dosing by goal, cycling logic, reconstitution, where to inject, and the full healing stack people are now calling Wolverine Plus. Plus troubleshooting, contraindications, and the FAQ on capsules, drug testing, bone on bone, and spine issues.There's also the story of how I found it, injecting one sore wrist and comparing it to the other.If you've stalled on the standard healing peptides, this one is for you.For research and entertainment purposes only. Subscribe for more peptide research and analysis.👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links
The LL-37 Masterclass | A Research Guide (2026)
2026/09/08
LL-37 is the peptide I think everyone should have on hand and almost nobody should be taking every day.
It's the only cathelicidin in the human body. That's an antimicrobial peptide your immune system makes to punch holes in bacteria, break up biofilms, and neutralize endotoxins. In this masterclass I walk through how it works. I cover why your vitamin D level decides whether your body can even make it. Then the specific situations where I reach for it. Stubborn sinus infections, bacterial acne, gut biofilms, suspected mold, and high-exposure travel windows.
I also cover who needs to stay away from it. Active autoimmune flares, rosacea, certain cancers, and mast cell issues can all go the wrong direction with LL-37.
Then dosing. I break down why I use 100 to 150mcg instead of the 2mg some people push. I go over how long a cycle should run and why maintenance dosing makes no sense. And I show how I sequence it with Thymosin Alpha 1, BPC-157, and TB-500.
One honest note. Almost all of the LL-37 data is preclinical or anecdotal. The only human trial is topical, and the lower doses beat the higher ones.
If you've ever wondered whether LL-37 belongs in your protocol, this one answers it.
For research and entertainment purposes only. Subscribe for more peptide research and analysis.
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links
Saturday Morning Coffee Talk 9/5/26
2026/09/05
All links here: https://hunterwilliamshealth.com/links
Ep. 8 | The Missing Layer | Yvonne Cropp on Color Puncture, Trauma, and Sovereignty
2026/09/04
We cover what color puncture actually is and the science behind it, how it works on the prefrontal cortex, why emotional trauma has the same cellular imprint as physical injury, what sovereignty actually means and why most people have given theirs away, how color helped Taylor heal plantar fasciitis that peptides and hormones could not touch, the GLP and anhedonia story that stopped me in my tracks, why your partner is not supposed to fill everything, and a lot more.This one goes deep. Not just on peptides but on what it actually means to know yourself.For research and entertainment purposes only.
⚠️ For research and entertainment purposes only.
⚠️👇 ALL MY LINKS IN ONE PLACE: https://hunterwilliamshealth.com/links
Connect with Yvonne:
Website: https://soulvessels.com/
Instagram: https://www.instagram.com/soulvessels
The NAD+ Masterclass | A Research Guide (2026)
2026/09/01
NAD+ is not a peptide. That one fact changes how you should use it.Peptides send a signal. NAD+ is a coenzyme, meaning it does the work itself. There is no receptor to downregulate, so the cycling logic is completely different.In this one I walk through what NAD+ actually does inside the cell, what burns through it, and whether it really crashes with age. The decline is real. It is just far more modest and tissue specific than the biohacking world tells you. Skin drops hard. Brain drops 10 to 13 percent across a lifetime. Liver and muscle barely move at all.I also get into the uncomfortable part. Injected NAD+ probably does not enter your cells intact. Surface enzymes break it down first, which means you may be paying a lot to deliver precursors.Then we cover dosing tiers, subQ versus IM, cycling blocks, methylation, what to track, and the 5-Amino-1MQ combo I run at much lower doses.I am not an NAD+ expert and I say so upfront. This is my lens on where it fits and where it does not.Fix your foundations first. Then decide if you actually need it.⚠️ For research and entertainment purposes only. ⚠️👇 ALL MY LINKS IN ONE PLACE https://hunterwilliamshealth.com/links
Ep. 7 | TRT, Fertility, and Hair Growth | Han Sijmons of Arcanum Health
2026/08/28
Han Sijmons flew in from Holland to sit down with Taylor and me and we just let it rip. Hans is a nurse, an EMT, and one of the most genuinely knowledgeable people I have met in this space. He came up through the same world as Alex Kikel and has been quietly coaching and optimizing people in Europe for years.We covered a lot of ground. His journey starting TRT in Holland as a younger guy and fighting the medical system to get taken seriously. The EMT and nurse peptide stack he built for high stress shift work. How he got his fertility back twice while on testosterone and what that protocol actually looked like. The KY19382 hair serum that outperformed a hair transplant in 14 weeks. Why finasteride is the number one inhibitor of sexual function out of the 600 most prescribed drugs. The GLP and hydration problem nobody is talking about. And a lot more.This was a really fun one. Han is the real deal.
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links
Connect with Han:
Instagram: https://www.instagram.com/arcanumcoaching
YouTube: https://www.youtube.com/@Arcanum-Health
Website: https://www.arcanum.health
⚠️ For research and entertainment purposes only. ⚠️
MGF and PEG-MGF Masterclass | A Research Guide (2026)
2026/08/25
If you already ran BPC-157 and TB-500 and still have a nagging injury, this one is for you.
MGF stands for mechano growth factor. It is a 24 amino acid fragment of IGF-1. That is the growth factor your body makes in response to training and damage. It came out of the bodybuilding world as a site injection peptide. That never panned out.
What it actually does is more interesting to me. It does not raise your IGF-1 levels. It seems to make your tissue more sensitive to the IGF-1 you already have. More bang for your buck out of what is already there.
I want to be straight about the evidence. Novartis and GlaxoSmithKline both tried to reproduce the original findings and failed. Human data is thin. Most of what we have is animal work on bone healing, cardiac recovery, and tissue quality.
I cover what MGF is and how PEG-MGF differs. Dosing tiers, cycling, injection technique, and troubleshooting. Plus how to stack it with BPC-157, TB-500, GHK, and growth hormone peptides.
Think of this one as a supporting actor. It makes everything else you are doing work better. It is not going to grow your glutes on its own.
⚠️ For research and entertainment purposes only. ⚠️
👇 ALL MY LINKS IN ONE PLACE https://hunterwilliamshealth.com/links
Saturday Morning Coffee Talk 8/22/26
2026/08/22
All Links Here: https://hunterwilliamshealth.com/links
Ep. 6 | Perimenopausal Women, GLPs, and the Peptide Wild West | Stephanie Gambetta of Loop Health
2026/08/21
Stephanie Gambetta flew out to North Carolina and sat down with Taylor and me for what ended up being one of the most honest conversations I have had about the peptide space.Stephanie runs Loop Health and has probably worked with more perimenopausal and menopausal women on peptides and GLPs than anyone in the country. She has the boots on the ground data that most people in this space do not have access to.We cover the biggest mistakes people are making right now, why women in their 40s and 50s are being thrown on GLPs before their hormones are even checked, the Adderall connection that nobody talks about, peptides in college culture and what parents need to know, the wild west of the research peptide industry, TFA versus acetate salt and why almost nobody selling peptides knows what that means, the SIBO and GLP connection, and where all of this is heading.Taylor jumps in throughout and this one covers a lot of ground.⚠️ For research and entertainment purposes only. ⚠️👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksExplore the Loop ecosystem and join the community: https://loop.health/stephaniegambettaConnect with Stephanie:https://www.stephaniegambetta.comhttps://www.instagram.com/stephanie_gambettahttps://www.instagram.com/loop.way
The Epitalon Masterclass | A Research Guide (2026)
2026/08/18
All Links Here: https://hunterwilliamshealth.com/links
Epitalon might be the most requested masterclass I have done. It might also be the most misunderstood peptide out there.
Most people run 5 to 10 milligrams a day because that number is everywhere online. I dig into where it actually came from, and it is not where you think. Those doses were built around epithalamin, the crude pineal extract from cow glands. Epitalon is the synthetic four amino acid version. They are not the same thing.
I walk through the pineal gland and why melatonin production falls off with age. I cover how Epitalon seems to skip the usual receptor route and go straight into the cell nucleus. That is the proposed mechanism behind the clock gene and telomerase effects.
I also cover the telomere data honestly. The 2025 work is in vitro, meaning cells in a dish, not people.
Then we get practical. My three dosing tiers. Cycling logic. How to sequence it with growth hormone peptides, DSIP, Thymalin, and Pinealon. Reconstitution, oral, and intranasal. Troubleshooting for the people who feel nothing, and the people who end up wired at night.
Plus the cancer question, which deserves a straight answer instead of a dodge.
Melanotan 1 and 2 Masterclass | A Research Guide (2026)
2026/08/11
All Links Here: https://hunterwilliamshealth.com/links
Melanotan 1 and Melanotan 2 are the two peptides people ask me about every summer. So I put together the full masterclass on both.
I combined them because you cannot really talk about one without the other. They came out of the same research program at the University of Arizona. But they hit different receptors, and that changes everything about how you use them.
We get into how the melanocortin system works and why sunlight is still required. I walk through the eumelanin shift, which is the pigment that actually protects you. Melanotan 1 is FDA approved for a rare light sensitivity condition. Melanotan 2 has three small studies from the 90s and a lot of gray market use.
I cover my dosing tiers, dosing by skin type, cycling patterns, and how to time a cycle around a beach trip or a wedding. I also cover what to stack it with and what to never run alongside. Then the side effects nobody warns you about. Nausea, flushing, darkening moles, and priapism are all real.
I talk honestly about the skin cancer question. Nobody knows for sure, and I say that.
My verdict is at the end. For most people it is not the one they expect.
Saturday Morning Coffee Talk 8/8/26
2026/08/09
All links here: https://hunterwilliamshealth.com/links
CJC-1295 Masterclass | A Complete Research Guide (2026)
2026/08/04
CJC-1295 is one of the most purchased peptides in the research space. It is also one of the least understood.Most people pick it up because a friend told them to. Then they run into side effects nobody warned them about. Around 70% get injection site reactions. Plenty get flushing, hives, or headaches. That does not make it a bad peptide. It just means you should know what you are walking into.In this one I cover both versions, DAC and no DAC, and where I land on each. We get into how GHRH analogs signal the pituitary to release growth hormone. I explain the four amino acid swaps and why they matter. We also talk about the halted 2006 trial and the death that still follows this compound around.Then we get practical. Dosing tiers, why fasting is not optional here, cycle length, and the order I would introduce ipamorelin. I also cover who should skip CJC entirely and what to track while you run it.Human data on CJC is thin compared to tesamorelin. I say so where it matters.If you are running it already or thinking about it, this is the full picture.⚠️ For research and entertainment purposes only. ⚠️👇 ALL MY LINKS IN ONE PLACE https://hunterwilliamshealth.com/links
Podcast reviews
Read The Hunter Williams Podcast podcast reviews
Jane Fankhauser 2026/09/02
Favorite podcast
The Hunter Williams Podcast is my go to podcast for all things peptides. Hunter communicates his knowledge & expertise in a concise & interesting mann...
Joey Garlenski 2026/09/01
Thank you Hunter
Best peptide podcast out there by a long shot. Very objective and detailed for every compound he discusses. Amazing this resource is free, thank you H...
GWillyD 2026/08/27
The Pod Father
I listen to a lot of podcasts, and hunger for knowledge around peptides: All roads lead back to Hunter. Even other podcasters reference his master cla...
HealthTwoOnw 2026/08/10
Honesty
Dangerous to rattle off a peptide for anything and everything as if any of it is proven through human-studies. Rats were tested in many cases. Be clea...
Jriefkrisb 2026/07/24
Just reads
I like this guy but all he does is read off stuff. I can do that on my own. He needs to watch JD and Will. They know their stuff and don't read pa...
TDG07 2026/07/21
Great Info
I listen to a lot of podcasts tying to really understand peptides. I think l this podcast is my favorite. I prefer when it’s just Hunter. I can’t get ...
1545Beachy 2026/07/18
Great content/average quality of recording
The content of your episodes is great. I struggle with Hunters voice volume, often you let the end of sentences “fall away” making it very difficult t...
Simply1246 2026/07/16
Say what?
I listened to the Mot-C podcast and had no clue what it meant. Sounded like you were speaking in a foreign language. Just keep it simple.
Dignan13 2026/07/14
So much great information
I found this podcast while trying to find information on peptides and haven’t stopped listening. Hunter does a phenomenal job explaining peptides from...
Jen Kruba-Couch 2026/06/30
Excellent Pep Education
One of the best peptide podcasts out there! Thank you for bringing this education to the forefront where we can learn from someone who has used and st...
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