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What happens when patients become partners in shaping clinical research? In this episode of the ISTH Pulse Podcast, host Dr. Julia Sandrin Gauer is joined by Dr. Sudeep Shivakumar and patient advocate Carol West to explore the role of patient perspectives in the EPCAT III trial, a Canadian-led study examining strategies to prevent venous thromboembolism (VTE) following hip and knee replacement surgery. The discussion highlights the collaboration between the EPCAT III research team and the CanVECTOR Patient Partners Platform, exploring how lived experiences can inform research priorities, trial design and clinical decision-making. Tune in to learn why bringing the patient voice into research matters and how meaningful collaboration can help shape future studies. Read the study here: www.nejm.org/doi/abs/10.1056/NEJMoa2603649?referrer=https%3A%2F%2Fwww.google.com%2F

Women can face unique blood clot risks across different stages of life, from hormonal contraception and pregnancy to the postpartum period and menopause. But there are still gaps in recognition and diganosis. In a special World Thrombosis Day episode of the ISTH Pulse Podcast, host Dr. Geoffrey Barnes is joined by experts Dr. James Douketis and Dr. Angela Weyand to ask an important question: Are we missing the warning signs? Together, they discuss where progress has been made, where gaps remain and what healthcare professionals can do to better recognize and address thrombosis risks in women. The conversation also explores broader challenges in women’s health, opportunities to improve research and clinical care and why this topic is at the center of the World Thrombosis Day campaign. Learn more and find resources at: https://www.worldthrombosisday.org/women-blood-clots/

In episode 3 of this ISTH Pulse Podcast miniseries, experts explore why next-generation mimetic therapies may be needed in hemophilia A and what they could add to an already evolving treatment landscape. The discussion examines how well current prophylactic options control bleeding, where treatment burden and unmet needs remain and whether less-frequent, subcutaneous dosing could support greater treatment convenience, adherence and access. Our experts also considers how factor VIII inhibitor status may influence treatment decisions and which patients could potentially benefit most as new mimetic therapies continue to develop. This episode is supported by an independent medical education grant from Bayer.

In the second episode of a special ISTH Pulse Podcast miniseries, experts explore why next-generation factor mimetics are being developed for hemophilia A and what unmet needs they may help address. The discussion examines the effectiveness of current prophylactic options, ongoing treatment burden and the potential role of less frequent, subcutaneous therapies in supporting treatment adherence and access. The episode also considers how factor VIII inhibitor status may influence treatment needs and what emerging factor mimetics could mean for the evolving hemophilia treatment landscape. This episode is supported by an independent medical education grant from Bayer.

In this first episode of a special ISTH Pulse Podcast miniseries, the discussion explores why next-generation mimetic therapies may be needed and where current treatment approaches may still leave gaps. The conversation examines whether existing prophylaxis provides adequate bleeding control, how treatment burden and less-frequent subcutaneous dosing may affect adherence and access and how factor VIII inhibitor status can influence treatment decisions. Tune in for a focused look at the evolving therapeutic landscape and the considerations shaping future approaches to hemophilia care. This episode is supported by an independent medical education grant from Bayer.

In this episode of the ISTH Pulse Podcast, host Julia Sandrin Gauer is joined by Dr. Sanjay Ahuja and Dr. Allison Wheeler to discuss the evolving landscape of factor mimetics for hemophilia A. They explore emerging therapies including Mim8, NXT007 and Inno8, the unmet needs that remain despite advances with emicizumab and factor replacement therapy, and what next-generation approaches could mean for the future of hemophilia care. The conversation also covers dosing, efficacy, safety, treatment switching and the patient populations that may benefit most as new therapeutic options continue to emerge. See a full transcript of this episode here: https://cdn.ymaws.com/www.isth.org/resource/resmgr/2026/transcript_for_podcast_1_sep.pdf

In this special episode of the ISTH Pulse Podcast, presented in collaboration with the Vasculearn Network, host Julia Sandrin Gauer is joined by Dr. Christian Ruff and Dr. Rushad Patell to discuss GLP-1 receptor agonists and their potential relationship with venous thromboembolism (VTE). The conversation explores what current evidence tells us about GLP-1 therapies and clotting risk, including the possible roles of weight loss, cardiometabolic health and inflammation. Tune in to hear more about the differences across GLP-1 medications, dual GIP/GLP-1 receptor agonists, patient populations that may warrant additional consideration and important gaps in the existing research.

Artificial intelligence (AI) is rapidly moving from the research setting into everyday clinical care, offering new possibilities for risk prediction, clinical decision support, image analysis and more. But as AI becomes increasingly integrated into healthcare, an important question emerges: Who’s really in charge? In this episode of the ISTH Pulse Podcast, we explore the legal and ethical considerations surrounding the use of AI in clinical practice. From accountability and physician responsibility to patient safety and responsible decision-making, tune in for a timely conversation about navigating the opportunities, responsibilities and emerging challenges of using AI in thrombosis and hemostasis care.

Immune thrombocytopenia (ITP) is often defined by a low platelet count, but its impact extends far beyond laboratory results. In this episode, Dr. Danny Hsu and Danielle Boyle discuss the latest findings from the global I-WISh 2.0 Study on patient and physician perceptions about ITP and explore ways to improve ITP patients’ quality of life. This episode is a must listen for people living with ITP and the physicians who care for them. Here are some additional resources to explore: https://onlinelibrary.wiley.com/doi/10.1002/ajh.70379 https://podcasts.apple.com/us/podcast/beyond-the-count/id1825045891

It's the final day of the ISTH Congress Daily Download! As #ISTH2026 comes to a close, join us for one last preview of the day's scientific program and a look back at an incredible week of discovery, collaboration and connection. This episode features a special message from plenary speaker David Lillicrap, along with highlights of today's State of the Art sessions and Oral Communications. Thank you for joining us throughout the ISTH 2026 Congress. We hope these daily updates helped you make the most of your experience in Paris, and we look forward to seeing you again next year!

The ISTH Congress Daily Download is back for Day 5 with your daily roundup of the science, education and networking opportunities happening across #ISTH2026. Start your day with a special plenary soundbite from Alisa Wolberg and a preview of the sessions you won't want to miss. Today's episode highlights Special Sessions, Oral Communications, Expert Insight Sessions, Poster Viewing Networking, Presentation Theaters and SSC Sessions, offering something for every attendee. We'll also remind you about the Networking Event, an opportunity to connect with colleagues from around the world and continue the conversations beyond the scientific program. Tune in for your daily guide to another exciting day at the ISTH Congress!

Description: Women experience unique hematologic health challenges throughout every stage of life, yet many remain underrecognized, underdiagnosed and underserved. In this special episode of the ISTH Pulse Podcast, host Julia Sandrin Gauer is joined by Bethany Samuelson-Bannow, Lan-Lan Smith and Maureen Achebe to discuss the launch of The Lancet Haematology Commission on Global Female Health and Haematology, released in conjunction with the Special Session at the ISTH 2026 Congress in Paris titled, "Periods, Pregnancy, Post-menopause and Poverty: The Lancet Haematology Commission on Global Female Health and Haematology." Listen as they explore why this landmark Commission was needed, the biological, social and structural factors shaping women's hematologic health, and the global inequities that continue to impact care. The conversation spans the female lifespan—from menstruation and pregnancy to menopause—while addressing topics including heavy menstrual bleeding, bleeding disorder diagnosis, pregnancy-associated thrombosis, postpartum hemorrhage, hormonal therapy-related thrombosis, maternal mortality disparities and the role of poverty and other social determinants of health.

Day 4 of the ISTH Congress Daily Download starts with a preview of today's program, including a special preview from plenary speaker Thomas Münzel. In this episode, we also highlight the State of the Art sessions, learn about a special session on women’s health, and preview today's Oral Communications. We'll also cover Expert Insight Sessions, Poster Viewing Networking, Presentation Theaters and SSC Sessions. Tune in for your daily guide to the research, education and conversations you won't want to miss at #ISTH2026.

The ISTH Congress Daily Download returns for Day 3 with everything you need to make the most of your day at #ISTH2026. In this episode, we preview today's State of the Art sessions, highlight a Special Session on regulatory topics, learn about late-breakthrough science, and look ahead to Oral Communications and the opening of the Exhibition Hall. Tune in for your daily guide to the science and key moments shaping the Congress.

Day 2 of the ISTH Congress Daily Download is here! Start your morning with a look at the exciting scientific and networking opportunities ahead. This episode features a message from plenary speaker Nathalie Bondil, plus a spotlight on the Early Career Session with insights from session chair Julia Sandrin Gauer. We'll also preview the Publications Session, Special Sessions, Supported Symposia, Oral Communications and SSC Sessions, before wrapping up with a reminder to join colleagues from around the world at the Opening Reception. Tune in each day for the highlights, updates and can't miss moments from #ISTH2026.