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Preconception Counseling for High-Risk Women   Guest: Katie Young, M.D. Guest: Carl Rose, M.D. Host: Marysia Tweet, M.D.   Preconception counseling for high-risk women focuses on identifying and optimizing cardiovascular, metabolic, and medical conditions before pregnancy to reduce maternal and fetal risk. This podcast highlights risk stratification, medication review, and delivery planning considerations that can meaningfully improve pregnancy and postpartum outcomes.   Topics Discussed: Core components of a comprehensive preconception evaluation How do tools like modified WHO classification and CARPREG II inform counseling? Cardiac medications and pregnancy Cardiovascular surveillance across pregnancy in high-risk patients    2025 ESC Guidelines for the management of cardiovascular disease and pregnancy: https://academic.oup.com/eurheartj/article/46/43/4462/8234487   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 08-January-2026

Common Scenarios in ACHD   Guest: Maan Jokhadar, M.D. Host: Malcolm Bell, M.D.   In this third and final episode discussing ACHD, Drs. Bell and Jokhadar review practical management considerations for adults with congenital heart disease, focusing on common conditions encountered in general cardiology and primary care. The discussion highlights bicuspid aortic valve disease and associated aortopathy, repaired tetralogy of Fallot and coarctation of the aorta, prosthetic valve management, anticoagulation and bridging decisions, and current recommendations for endocarditis prophylaxis. Emphasis is placed on surveillance, complication prevention, and thoughtful risk–benefit assessment in routine and procedural care. Be sure to listen to the previous two episodes, “The Hospitalized ACHD Patient” and “ACHD for the Primary Care Provider.”   Topics Discussed: Bicuspid Aortic Valve (BAV) Coarctation of the Aorta (COA) Tetralogy of Fallot (TOF) Mechanical and Bioprosthetic Valves Anticoagulation Management Subacute Bacterial Endocarditis (SBE) Prophylaxis   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 04-November-2025

Menorrhagia Management in Women with Cardiovascular Disease   Guest: Shannon Laughlin-Tommaso, M.D. Host: Marysia Tweet, M.D., M.S.   Heavy menstrual bleeding is a condition that occurs before menopause and can be caused by both hormonal and structural conditions, like fibroids or adenomyosis. There are many medical and procedural options for treating bleeding which are safe in women with CVD. Although hysterectomy is a definitive option for HMB, it can increase risks of CVD in young women.   Topics Discussed: What are the causes of heavy menstrual bleeding? what are the options for treating heavy menstrual bleeding in patients on or off anticoagulation?  Is heavy menstrual bleeding a risk factor for CVD?    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded 06-January-2026

ACHD for the Primary Care Provider   Guest: Maan Jokhadar, M.D. Host: Malcolm Bell, M.D.    This is the second of three episodes on adult congenital heart disease. Be sure to go back and listen to episode one, “The Hospitalized ACHD Patient.” In this episode, listeners will hear a primer on caring for adults with congenital heart disease (ACHD) in the primary care setting. Dr. Malcolm Bell and Dr. Maan Jokhadar discuss when ACHD patients should be referred for specialized evaluation, how to locate clinics, and which symptoms should raise concern. Key practical tips are shared to help avoid common pitfalls and ensure safe, effective care for this unique patient population.   Topics Discussed: Do all patients with CHD need to be seen in an ACHD clinic? How to locate ACHD clinic? What are some alarm symptoms for ACHD? Common pitfalls to avoid   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 04-November-2025

Pacing and Defibrillation Without Leads   Guest: Nicholas Tan, M.D. Host: Anthony Kashou, M.D.   In this episode, listeners will hear about the history of pacemakers and defibrillators, both with and without leads. Potential risks and complications associated with transvenous cardiac devices are discussed. The listener should gain an awareness of leadless pacing and extravascular defibrillator systems.   Topics Discussed: What are some of the risks associated with transvenous device implants? What is leadless pacing, and how is it generally performed? How does a defibrillator without transvenous leads work? When will you consider “transvenous-free” pacing or defibrillation systems?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   09-December-2025

The Hospitalized ACHD Patient   Guest: Maan Jokhadar, M.D. Host: Malcolm Bell, M.D.   This is the first of three episodes on adult congenital heart disease. Adults with congenital heart disease are often admitted for a wide range of cardiac and non-cardiac issues, many of which carry unique management considerations. This episode emphasizes the importance of early ACHD consultation, especially in patients with cyanosis or prior complex repairs, and why even “simple” lesions deserve careful attention. We also touch on key bedside considerations that can significantly impact outcomes if overlooked. The goal is to build awareness and confidence when caring for this growing and complex patient population.   Topics Discussed: Why are ACHD patients admitted?  When should a practitioner consult ACHD for their patient?  What are some of the common pitfalls to avoid?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 04-November-2025

Does Lifestyle Affect Pregnancy and Congenital Birth Defects?   Guest: Katie Young, M.D. Guest: Carl Rose, M.D. Host: Marysia Tweet, M.D., M.S.   Lifestyle choices before and during pregnancy can shape both maternal cardiovascular risk and fetal development. In this podcast, we explore how lifestyle factors before and during pregnancy influence maternal cardiovascular health and pregnancy outcomes.   Topics Discussed: If a woman wishes to become pregnant, what can she do to minimize risk of adverse events during pregnancy or the postpartum period?  Are there certain lifestyle choices that are known to cause pregnancy complications?  Are there certain lifestyle choices that are known to cause congenital birth defects?  Are there any women for whom you would advise daily baby aspirin during pregnancy?  Are there lifestyle factors that should prompt enhanced fetal cardiac surveillance? What cardiovascular or metabolic risk factors should ideally be optimized before conception? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.

Gene Therapy and Genetic Cardiomyopathies   Guest: John Giudicessi, M.D., Ph.D. Host: Malcolm Bell, M.D.   In this podcast, listeners will learn what gene therapy is and the types of genes therapies under development for an array of genetically mediated cardiovascular disorders. In addition, active and upcoming gene therapy clinical trials for the treatment of specific arrhythmogenic, dilated, hypertrophic and restrictive cardiomyopathy genotypes will be discussed.   Topics Discussed: What is gene therapy? How do gene therapies differ from conventional management of genetic arrhythmogenic, dilated, hypertrophic and restrictive cardiomyopathies? Are there different types of gene therapies? What gene therapy trials are currently active or upcoming at Mayo Clinic and other institutions?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded 21-October-2025

Leadless Pacemakers and Extravascular ICDs   Guest: Alan M. Sugrue, M.B., B.Ch., B.A.O. Host: Sharonne Hayes, M.D.   This episode of “Interviews With the Experts” explores how leadless pacemakers and extravascular ICDs are redefining device therapy by minimizing lead- and pocket-related complications while expanding options for patients with complex anatomy or infection risk. Listeners will learn how these systems differ from traditional transvenous technologies, review key data on safety and efficacy, and understand which patient profiles are best suited for each approach.   Topics Discussed: How do leadless pacemakers differ from traditional transvenous systems in terms of technology, complication profile, and clinical outcomes? In which patient populations should leadless pacing be considered as a first-line option? What are the key design and functional differences between extravascular and subcutaneous ICDs? What advantages and limitations should clinicians understand when deciding between these two systems?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded 21-October-2025

Translating the DGA Into Real-World Cardiometabolic Care   Guest: Stephen L. Kopecky, M.D. Host: Kyla M. Lara-Breitinger, M.D., M.H.S.   In this third episode roundtable, Dr. Lara Breitinger and Dr. Steve Kopecky examine what the DGAs get right—and where they fall short—for cardiovascular risk, from their emphasis on whole-food patterns to ongoing gaps around food processing, nutrient oversimplification, and sustainability messaging. They share how they translate the guidelines into real-world cardiometabolic care, including the evidence-based principles they use in clinic and when to individualize beyond national recommendations. Looking ahead, they explore the future of nutrition guidance—food as medicine, precision cardiometabolic care, and outcomes-driven recommendations—reminding listeners that the DGA is a starting point and to focus on "one bite at a time."   Topics Discussed: The mismatch between guidelines and patients What the DGA gets right—and wrong—for CV risk How you counsel patients today Where nutrition guidance needs to go next   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 10-February-2026

Applications of the New DGA   Guest: Tara Schmidt, RDN, LD Host: Kyla Lara-Breitinger, M.D., M.H.S.   Every five years, new dietary guidelines for Americans are put out by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA). The Dietary Guidelines for Americans, 2025-2030 (10th edition) was recently published in early 2026 and has sparked some controversy with not only its visual icon, but some of its emphases as well. In this second episode reviewing the new DGA, Dr. Kyla-Lara Breitinger and Tara Schmidt, RDN, LD review what the new guidelines advise and what may be confusing for consumers.     Topics Discussed: Do you want to share a bit of history around the DGAs? What recommendations from the new DGAs align with longstanding nutrition science? Are there elements of the new guidelines that raise any concern? What should be some key nutritional focuses for Americans, given what we know about their health status?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 05-February-2026

Dietary Guidelines of America: What Changed, What Didn’t, and Why it Matters   Guest: Dariush Mozaffarian, M.D., Dr.P.H. Host: Kyla Lara-Breitinger, M.D., M.H.S.   The release of the new Dietary Guidelines for Americans has sparked important conversations across medicine, public health, and clinical practice. In this three-episode Interview with the Experts mini-series, Mayo Clinic preventive cardiologist Dr. Kyla Lara-Breitinger brings clarity to what the guidelines mean for patients and clinicians alike—cutting through headlines, controversy, and confusion with evidence-based insights from national and Mayo Clinic experts. Together, we explore what’s new, what remains unchanged, where debate persists, and how these guidelines translate into real-world cardiometabolic care, with a strong emphasis on practical, patient-centered nutrition advice.   Topics Discussed: Why does the new DGA matter for cardiology? What’s new vs. recycled? Core controversies Clinical takeaways   Referenced article: Mozaffarian D. The 2025-2030 Dietary Guidelines for Americans. JAMA. Published online January 14, 2026. doi:10.1001/jama.2026.0283 The 2025-2030 Dietary Guidelines for Americans | Lifestyle Behaviors | JAMA | JAMA Network    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 27-January-2026

Conduction System Pacing   Guest: Nicholas Tan, M.D., M.S. Host: Anthony Kashou, M.D.   In this episode of the “ECG Making Waves” segment of Mayo Clinic’s cardiovascular podcast series “Interviews with the Experts,” Dr. Nicholas Tan joins us to discuss conduction system pacing. The listener will hear about the basics and rationale of conduction system pacing, as well as clinical scenarios where it should be considered.   Topics Discussed: How does conduction system pacing (or CSP) differ from conventional means of pacing? In broad strokes, how is CSP performed? In what situations would you consider doing CSP? Are there any risks or uncertainties regarding CSP?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded 09-December-2025

AI Detection of Cardiac Amyloidosis   Guest: Patricia Pellikka, M.D. Host: Malcolm Bell, M.D.   Dr. Patricia Pellikka dives into the AI model she helped build. Working with an AI echo company, Ultromics Ltd., her team built an AI echo model to detect cardiac amyloidosis. The model works from an apical 4 chamber videoclip and was approved by the FDA via the breakthrough pathway. They have validated it internationally in a population with 22% prevalence of cardiac amyloidosis and it had a sensitivity of 85%, specificity 93%, PPV 78%, NPV 96%, and AUC 0.93.  The performance of the model was consistent across cardiac amyloid types; among AL, wild type ATTR, and hereditary ATTR, the sensitivity was 84%, 85%, and 86%, respectively.  The performance of the model was also superior to previously validated scores which use clinical and echocardiographic variables for detecting cardiac amyloidosis. The results of the study were published online in the European Heart Journal in July.   Topics Discussed: You have built an AI echo model to detect cardiac amyloidosis.  How did you get into this? Tell us about the model that you built. How did you validate it? How does the model compare with other screening methods for detecting cardiac amyloidosis? What are the next steps for your research?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.

Clopidogrel Monotherapy in Chronic Coronary Artery Disease   Guest: Keri Zieminski, APRN, C.N.P., D.N.P. Host: Sharonne Hayes, M.D.   This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of clopidogrel monotherapy in patients with chronic CAD that are not on anticoagulation. Discussion will include why there has been a shift towards redefining antiplatelet medical therapy for this patient population, brief overview of recent trials, and how to manage a patient on clopidogrel monotherapy that needs to undergo noncardiac surgery.   Topics Discussed: Why has there been a shift towards redefining antiplatelet medical therapy in patients with chronic CAD? What's changed? Recently published trials that highlight clopidogrel monotherapy. What is your process for managing a patient on clopidogrel monotherapy that needs to go for noncardiac surgery?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.