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★★★★★

4.9

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Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform better in business, optimize your daily routines, achieve peak performance, biohacking your age, and more. Claudia is a Peak Performance Coach and Serial Entrepreneur passionate about helping you thrive in all areas of your life & business! She knows what it’s like to feel close to burnout and not be at your best. Thanks to 10+ years of research, countless interviews with global pioneers, and hundreds of thousands spent, she continues to uncover how you, too, can achieve peak performance to live your life at its best - all while having lots of fun! So make sure to TUNE IN and start living the best version of yourself!

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#246 Claudia von Boeselager on Women Who Lead And Sell Podcast | Reverse Your Biology, Reclaim Your Power: From Burnout to Biohacking & Purpose

2026/04/23

Claudia von Boeselager is a former Goldman Sachs banker turned biohacker, longevity entrepreneur, peak performance coach, and investor who reversed her biological age by 18 years. In this conversation, she shares the burnout moment that changed everything, what biohacking really means beyond supplements and gadgets, how purpose and alignment affect health and performance, and why women can use their biology as an advantage in leadership, business, and life. [00:00] Introduction to Claudia’s journey [03:00] Purpose, alignment, and “following your bliss” [07:00] What biohacking really means [15:00] The burnout moment that changed everything [20:00] Women, leadership, and playing small [30:00] Female biology as a business advantage [40:00] Sales, money mindset, and impact [50:00] Building businesses with purpose [58:00] Rapid-fire insights and lessons Claudia von Boeselager is the founder of Longevity & Lifestyle, a platform focused on helping ambitious people optimize health, performance, and lifespan through science-backed tools, expert insights, and practical strategies. Her work sits at the intersection of longevity, women’s health, biohacking, and high performance. Newsletter: https://longevity-and-lifestyle.com/llinsider Website: https://longevity-and-lifestyle.com/ Follow on Instagram: https://www.instagram.com/longevityandlifestyle/ Follow Claudia on LinkedIn: https://www.linkedin.com/in/claudia-von-boeselager Subscribe on YouTube: https://www.youtube.com/channel/UCZF-s8jsUejc0TpVqnFE1lQ

#245 Matt Abrahams — Why You Freeze Under Pressure: How to Think Faster, Speak Smarter & Communicate with Confidence

2026/04/23

Ever blanked in a meeting or "frozen" during a big presentation? You aren't alone. Communication expert Matt Abrahams joins Claudia von Boeselager to explain the science of why high performers blank out and how to rewire your brain to stay calm and clear. Download my FREE 10 Life & Longevity Hacks Playbook to start living smarter and stronger: https://longevity-and-lifestyle.com/freebie In this episode, we dive into: 00:00 – Why smart people "freeze" when the stakes are high05:30 – The biology of anxiety and cognitive overload12:00 – Why connection matters more than perfection18:45 – The "Pace, Space, Grace" framework for better listening25:10 – How to use structure instead of memorization32:00 – Practical tools for high-stakes interviews & meetings40:00 – The key to becoming a master communicator Additional Resources: ✨ Join the LLInsider for peak performance strategies: https://longevity-and-lifestyle.com/llinsider ✨ Full show notes & links: http://longevity-and-lifestyle.com/podcast-245-matt-abrahams #LongevityAndLifestyle #CommunicationSkills #MattAbrahams #PublicSpeaking #MindsetShift #PeakPerformance #LeadershipDevelopment

#244 I Lost My Voice for 3 Days - Here’s What It Taught Me | Claudia von Boeselager

2026/03/25

In this personal solo episode, Claudia shares a powerful and unexpected experience - losing her voice completely for three days. What initially felt frustrating became a profound reminder of how the body communicates when we’re moving too fast. In this reflective conversation, Claudia explores the deeper meaning behind forced silence and what it taught her about listening, slowing down, and reconnecting with our inner signals. In this episode we explore: • What losing her voice revealed about stress and overextension • Why the body often speaks before burnout appears • The hidden intelligence of the body and how it communicates with us • The power of silence and stillness in a hyper-stimulated world • How to start listening more carefully to your body’s signals This episode is an invitation to slow down, reflect, and reconnect with the wisdom already within you.

#243 Dr. Meenal Agarwal - The Eye-Brain Connection, Screen-Induced Vision Loss & Spatial Awareness: How Modern Life Is Rewiring Your Brain

2026/03/18

What if your vision was telling you far more about your health than you realized? In this fascinating episode, Dr. Meenal Agarwal, board-certified optometrist, spatial awareness expert, and authority on the eye–brain connection, reveals how vision is not just about eyesight - it’s a direct reflection of brain function, nervous system state, and emotional health. Blending clinical science, neuroscience, mindfulness, and compassion, Dr. Agarwal explains how stress, trauma, and chronic overload subtly alter how we see the world - and how retraining vision can support healing, resilience, and longevity. From spatial awareness to visual processing, this conversation reframes vision as an active brain skill and a powerful portal into whole-body wellbeing. We explore: The eye–brain connection and nervous system regulationHow stress and trauma show up in visionSpatial awareness and its role in balance, safety & longevityWhy vision is a brain function, not just an eye issueHow mindful vision practices can support healing and clarity This episode invites you to see differently - both literally and metaphorically.

#242 Olga Kaplan — Sacred Sexuality, BDSM, Trauma Healing & Intimacy: Reclaiming Pleasure, Power & Emotional Safety

2026/03/12

What if desire isn’t indulgence - but your life force? In this deeply embodied conversation, intimacy and sacred sexuality coach Olga Kaplan returns to explore how trauma lives in the body, why intimacy is about presence, and how conscious kink and BDSM can be used therapeutically for healing. We explore: • What intimacy truly means (deep presence with yourself and another) • Tantra as weaving life experiences into embodied aliveness • The difference between kink, BDSM and trauma-informed practice • Why trauma is not the event — but what happened without consent • How impact play, consent and role dynamics can help rewire the nervous system • Why libido is a powerful biomarker of health and vitality • The “sex recession” and why younger generations are disconnecting • Practical tools: breath, sound, movement & energetic hygiene • How long-term couples can revive polarity, play and desire This episode is about reclaiming your body, your pleasure, your vitality — and remembering that your desire is not shameful, it’s sacred.

#241 Dr. Chris Davis & LUMARA Collective - The Real Cause of Heart Aging: Oxidative Stress, Nitric Oxide & Vascular Health

2026/03/04

What if “heart health” isn’t about managing numbers… but fixing what’s driving vascular aging in the first place? In this episode, triple board-certified cardiologist Dr. Chris Davis joins Claudia (with Lumara co-founders Ashley Madsen and Alexandra Cochrane) to unpack a modern, prevention-first approach to cardiovascular longevity. We explore: Why conventional cardiology often becomes a “revolving door” of repeat events and proceduresThe “getting rusty inside” explanation of oxidative + nitrosative stress (and what it does to your arteries)How nitric oxide signaling influences vascular function, performance, and agingWhy Lp(a) is trending, what matters now, and how to think about outcomes vs numbersWhy coronary imaging (calcium and plaque assessment) can remove the guessworkHow toxins, membranes, and mitochondria connect to cardiometabolic declineThe emerging frontier: membrane medicine + mitochondrial support (including peptide discussion)Practical levers you can start with: Zone 2, environment upgrades, and reducing daily toxin load This is a high-signal conversation for anyone who wants to measure what matters, reduce risk upstream, and build a stronger, longer healthspan.

#240 Dr. Louise Hecker — Can Psilocybin Slow Aging? The First Study on Telomeres, Cellular Longevity & Systemic Anti-Aging

2026/02/25

What if psilocybin wasn’t just a mental health breakthrough — but a longevity intervention? In this powerful, science-driven conversation, Dr. Louise Hecker shares groundbreaking research exploring how psilocybin’s active metabolite, psilocin, may influence the fundamental biology of aging. We explore: • How psilocybin impacts cellular senescence, one of the key drivers of aging • The surprising effects on oxidative stress and antioxidant pathways • What happened to telomere length in aging cell models • Why serotonin (5-HT) receptors exist throughout the body — not just the brain • The dramatic survival results in aged mice given monthly high-dose psilocybin • Why psychedelic research was stalled for decades — and what’s changing now • The potential role of psilocybin as a future geroprotective agent This episode moves beyond hype and into mechanism — exploring how psychedelics may influence healthspan at the cellular and systemic level. A fascinating look at how a once-misunderstood compound could reshape preventative medicine and aging science.

#239 Dr. Ash Kapoor — Root Cause Longevity: Fasting, Trauma Healing, Detox & Reversing Chronic Disease

2026/02/18

What if aging, fatigue, and chronic disease all shared the same root cause? In this episode, Dr. Ash Kapoor, physician and expert in precision and longevity medicine, reveals why mitochondrial dysfunction sits at the center of metabolic breakdown, cardiovascular disease, inflammation, and accelerated aging. Rather than focusing on symptoms, Dr. Kapoor explains how cellular energy production determines how well we heal, perform, and age. We explore why calorie counting misses the mark, how modern lifestyles damage mitochondrial function, and why restoring metabolic flexibility is one of the most powerful levers for longevity. This conversation reframes health from surface-level metrics to what’s happening deep inside the cell. We explore: Why mitochondria drive energy, inflammation & agingThe link between metabolic dysfunction and chronic diseaseHow precision diagnostics reveal early dysfunctionWhy weight is a poor proxy for metabolic healthWhat actually restores cellular energy & resilience This episode offers a clear, science-based roadmap for rebuilding energy and extending healthspan—starting at the cellular level.

#238 Naveen Jain – Moonshot Thinking, Imagining a World Where Illness Is Optional: AI, Microbiome Intelligence & Reversing Chronic Disease

2026/02/12

What if disease wasn’t inevitable — but preventable? In this thought-provoking episode, visionary entrepreneur and philanthropist Naveen Jain challenges the foundations of modern medicine and makes the case for a bold new approach to longevity. Known for his moonshot mindset, Naveen explains why healthcare is broken, why we wait until we’re sick to act, and how proactive diagnostics and gut health could radically extend healthspan. Drawing on his work in microbiome research, data-driven diagnostics, and preventive health, Naveen shares why curiosity, accountability, and big thinking are essential if we want to end chronic disease — not just manage it. We explore: Why reactive medicine fails long-term healthThe role of gut health in disease preventionHow diagnostics can predict illness years earlierMoonshot thinking applied to longevityWhat it really takes to live disease-free longer This conversation is a wake-up call — and an invitation to rethink what’s possible for human health. This epidsode was brought to you by: Kineon

#237 Dr. Shivani Gupta — On Ayurveda Meets Modern Science: Inflammation, Gut Health, Circadian Rhythm & Personalized Longevity

2026/02/04

Inflammation may feel like a modern problem — but Ayurveda understood it over 5,000 years ago. In this deeply grounding episode, Dr. Shivani Gupta, Ayurvedic practitioner, researcher, and author of The Inflammation Code, reveals how ancient Ayurvedic wisdom is finally being validated by modern science. From circadian rhythm and gut health to nervous system regulation and women’s hormones, Dr. Shivani explains why so many of us are chronically inflamed — and how simple daily rituals can restore balance, energy, and longevity. We explore why inflammation, not aging, is driving fatigue, brain fog, hormonal chaos, and perimenopause symptoms, how “mental inflammation” manifests in the body, and why turmeric and other adaptogenic herbs remain some of the most powerful anti-inflammatory tools available. We explore: Why inflammation is the real root of chronic diseaseVata, Pitta & Kapha — and how personalization really worksGut-brain connection through an Ayurvedic lensMental inflammation, stress & nervous system overloadHow rhythm, sleep, food & ritual restore vitalityThis is a powerful reminder that healing doesn’t require more force — it requires alignment.

#236 Mastering HRV & Nervous System Sovereignty — How Emotional Athleticism Shapes Longevity, Leadership & Stress Resilience with Salim Najjar

2026/01/28

What if stress wasn’t your enemy—but your greatest teacher? In this episode, nervous system and HRV expert Salim Najjar reveals how heart rate variability acts as the language of the nervous system, guiding us toward emotional resilience, clarity, and longevity. Drawing from his own journey—from entrepreneurial burnout to nervous system sovereignty—Salim explains why learning to regulate stress is no longer optional in modern life. We explore How childhood patterns shape adult reactionsWhy you can’t think your way out of overwhelmHow practices like breathwork, sleep, reframing, and community can transform both health and performance. This conversation reframes stress as a training ground and HRV as the compass back to balance, purpose, and embodied leadership. This episode was brought to you by: CAROL BikeKineon

#235 Dr. Kelly Starrett - On Building a Durable Body for Life, Pain-Free Longevity, Mobility, Sleep & the Power of Daily Movement

2026/01/23

What if pain isn’t a sign of damage — but a signal for change? In this powerful conversation, Dr. Kelly Starrett, world-renowned coach, physical therapist, and co-founder of The Ready State, breaks down what actually keeps the human body healthy, mobile, and resilient across a lifetime. From movement and sleep to nervous system safety and social connection, Kelly explains why most people are chasing optimization while ignoring the fundamentals that truly matter. We explore why sitting is quietly destroying mobility, how the brain interprets pain as threat, why movement signals safety to the nervous system, and how small daily habits — like walking, sitting on the floor, breathing, and sleeping consistently — compound into extraordinary long-term health. We explore: Why pain is information, not damageHow mobility restores nervous system safetyThe overlooked role of sleep, walking & playWhy adherence matters more than intensityHow to build a body that supports adventure, not fear This episode is a return to basics — and a reminder that longevity isn’t about doing more, but doing what matters, consistently. This Episode was brought to you by: CAROL Bike

#234 Emotional Biohacking, Brain DNA & Rewiring Stress for Longevity With Dr. Alok Trivedi (Dr. Rewire)

2026/01/14

What if your stress responses, emotional patterns, and even motivation weren’t flaws to fix but signals to understand? In this powerful episode, Dr. Rewire (Dr. Alok Trivedi) reveals how emotional biohacking and brain DNA insights can transform the way we relate to stress, performance, and ourselves. Drawing on nearly three decades of clinical experience, Dr. Rewire explains why emotions are data, not directives and how rewiring the nervous system can unlock peace of mind, resilience, and longevity. We explore how personalised brain DNA patterns influence motivation, stress tolerance, recovery, and relationships and why one-size-fits-all biohacking often backfires. This conversation reframes mental health from “fixing what’s broken” to understanding how the brain is designed to protect us and how to work with it instead of against it. We explore: Emotional biohacking and nervous system regulationBrain DNA, neurotransmitters & neuroflexibilityWhy stress, anxiety & burnout are adaptive signalsPersonalised approaches to mindset, health & longevityHow to rewire emotions for clarity, balance & peace of mind This is a grounded, empowering conversation that invites you to know yourself — scientifically and live in alignment with your unique design. Tune in!

#233 The Science of Hunger: GLP-1, Appetite Control & Natural Weight Management With Sarah Kennedy

2026/01/08

Why does hunger feel so loud — and why does willpower so often fail? In this illuminating episode, Sarah Kennedy, founder and CEO of Calocurb, unpacks the biology of hunger, the gut-brain axis, and the powerful role of GLP-1 in appetite regulation. Drawing on over 15 years and $30 million of New Zealand government-backed science, Sarah explains why hunger is driven by our most primitive brain systems — and how understanding this biology can finally bring peace with food. We explore how bitter taste receptors in the gut stimulate appetite-suppressing hormones, why dieting can actually increase hunger over time, and how natural GLP-1 activation differs fundamentally from pharmaceutical injections like Ozempic. We explore: The evolutionary biology of hunger and food noiseHow GLP-1, CCK and PYY regulate appetiteWhy calorie restriction backfires long-termNatural vs synthetic GLP-1 pathwaysHow appetite regulation supports metabolic health, insulin sensitivity & longevity This is a science-grounded, compassionate conversation that reframes hunger — not as a personal failure, but as biology you can finally work with. This episode was brought to you by: Calocurb

#232 Jenn Drummond — The Moment That Changed Everything: Near-Death, Everest & Building Unbreakable Resilience

2025/12/18

What happens when life gives you a second chance? In this powerful episode, world-record mountaineer, author, and resilience expert Jenn Drummond shares how surviving a near-fatal car crash became the defining line between the life she was living — and the life she chose to claim. From promising she’d “do something significant” if she lived, to summiting Everest and completing the second-highest peaks on every continent, Jenn reveals why courage isn’t something you’re born with — it’s something you build, one brave step at a time. We explore: How trauma can become a catalyst for purposeWhy courage is trained, not innateThe mindset that turns fear into forward motionWhat it means to shift from success to significanceHow to model resilience for your children — and yourself This is a deeply human conversation about choosing life, rewriting identity, and climbing the inner mountains that matter most. This episode was brought to you by: CarolbikeKineonCalocurb

Podcast reviews

Read The Longevity & Lifestyle Podcast podcast reviews

4.9 out of 5

28 reviews

★★★★★

Matt gerlach 2024/08/27

This podcast is everything I wish I knew when I started my healing journey

Everything on this podcast is incredible. We need to take care of our body holistically, and this podcast has given me so many ideas about ways that I...

★☆☆☆☆

Mike797979 2025/02/04

Buyer Beware

Plenty of purveyors of, at best, pseudoscientific ideas and practices are hosted on this podcast. Calling some of them outright conspiracy theorists w...

★★★★★

Lienna M 2024/07/05

My new favorite ❤️

Claudia von Boeselager is here to empower you to live at your best and reach your highest potential. I absolutely love this podcast because Claudia sh...

★★★★★

Mike Modula 2023/06/26

Insightful and thought provoking

This podcast breathes new life into topics that impact day to day life! I love the interesting perspectives that the guests bring which have allowed m...

★★★★★

fear into joy 2023/05/02

Powerful and Expansive Content!

I’m so thankful for the extensive content that has been thoughtfully cultivated and curated by Claudia! She’s brought top thought leaders and cutting ...

★★★★★

danafrost 2022/06/21

Go to longevity podcast

Claudia brings forth cutting edge Biohackers & lifestyle experts. She asks probing questions and the conversations keep me wanting more.

★★★★★

Adarcus 2022/06/16

Learn something new each time!

Longevity

★★★★★

Mandy J Russell 2021/06/25

Love your life, own your well-being!

Claudia had managed to put together a wide ranging group of experts who have opened my eyes to new thinking and approaches in an area that is already ...

★★★★★

JonathanQuick 2021/06/17

Must listen to anyone trying to improve their health

Claudia is bringing on incredible guests who are at the forefront of thinking about how to improve our health. This podcast gives actionable steps on ...

★★★★★

philgartennispro 2021/06/09

Lifestyle and Longeviy podcast

A very interesting podcast for me and my friends and I look forward to more episodes.

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