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In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, interviews Dr. Brent Sear, director of the Clinical Pharmacology Shared Resource at KU Cancer Center. Brent shares his unique career journey into clinical pharmacology, the role of clinical pharmacology in advancing cancer therapies, and the critical work his team does in guiding clinical trials and personalizing cancer treatment. They also discuss emerging technologies and their potential impact on the future of cancer research. Tune in to learn more about the intricate processes that ensure safe and effective cancer therapies. 00:00 Introduction to the Podcast and Guest 01:06 Brent Sear's Journey into Cancer Research 03:21 Understanding Clinical Pharmacology 04:54 The Role of Clinical Pharmacology Shared Resource 06:40 Importance of Precise Measurement in Cancer Treatment 08:40 Collaborative Projects and Scientific Insights 09:55 Advice for Aspiring Researchers 11:52 Future of Clinical Pharmacology in Cancer Research 13:33 Conclusion and Farewell Links from this Episode: ·       Learn more about the Clinical Pharmacology Shared Resource at KU Cancer Center ·       Learn about Brent Sear, director of the Clinical Pharmacology Shared Resource ·       Learn about Shared Resources and Core Facilities at KU Cancer Center To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, hosts Dr. Kristy Brown, a nationally recognized expert in cancer metabolism and hormone signaling. Dr. Brown discusses the latest breakthroughs in understanding the relationship between obesity, estrogen, and cancer, along with how these discoveries shape more effective treatments. She reflects on her career and shares moving accounts of patient interactions that fuel her research. The conversation delves into emerging opportunities in cancer treatment and prevention, the role of artificial intelligence in research, and offers advice for early-career scientists on making a meaningful impact. Dr. Brown expresses optimism for future cancer research advancements and the potential for improved patient outcomes. 00:00 Introduction to the Podcast and Today's Topic 00:28 Meet Dr. Kristy Brown: Expert in Cancer Metabolism 01:02 Optimism in Cancer Research: Key Developments 02:31 Proud Moments in Cancer Research 04:15 Obesity, Metabolism, and Cancer: Emerging Discoveries 06:10 Translational Research: From Lab to Clinic 09:08 Advice for Early Career Scientists 12:18 Hope for the Future: Personal Reflections 13:24 Conclusion and Resources Links from this Episode: ·       Learn more about Dr. Kristy Brown ·       Learn about Dr. Brown's research ·       Learn about cancer prevention at KU Cancer Center To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

In this episode of Bench to Bedside, Dr. Roy Jensen speaks with Dr. Anna Arthur and Dr. Gregory Gan about their innovative cross-disciplinary work at the intersection of nutrition and radiation oncology. They explore how their combined expertise leads to holistic cancer treatment approaches, focusing on the effects of diet, inflammation, and treatment response on patient outcomes. Both experts share their personal and professional journeys into their respective fields, the collaborative projects they have undertaken, and the way they integrate multidisciplinary insights into improving cancer care. They also highlight their efforts to mentor the next generation of researchers, underscoring the value of collaboration in scientific innovation. 00:00 Introduction to Cross-Disciplinary Collaboration 00:41 Meet the Experts: Dr. Anna Arthur and Dr. Gregory Gan 00:48 Journey into Their Respective Fields 02:02 Challenges and Realizations in Cancer Research 05:22 The Intersection of Nutrition and Radiation Oncology 10:28 Collaborative Projects and Their Impact 19:31 Mentoring the Next Generation of Researchers 23:14 Future Directions in Integrating Nutrition and Cancer Treatment 25:04 Conclusion and Final Thoughts Links from this Episode: ·       Learn more about Dr. Anna Arthur ·       Learn about Dr. Gregory Gan ·       Learn about the Nutrition Shared Resource at the cancer center ·       Learn about head and neck cancer To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, talks with Marilyn Mahan and Karl Frees, members of Patient and Investigator Voices Organizing Together (PIVOT) – KU Cancer Center's patient research advocacy group – and co-chairs of the PIVOT Educational Task Force. They discuss PIVOT, an initiative bringing patients, survivors, caregivers, and researchers together to enhance cancer research. Marilyn and Karl share how PIVOT integrates patient perspectives into research, the ways advocates collaborate with researchers, and the program's impact on studies and researcher motivation. Both guests recount their personal cancer journeys and their dedication to influencing cancer research to become more patient-centered and effective. They stress the importance of patient advocacy, the empowerment that comes with shared knowledge, and the future goals of expanding PIVOT's reach and impact. 00:00 Introduction to Bench to Bedside 00:18 What is PIVOT? 02:03 How PIVOT Advocates Collaborate with Researchers 04:15 Impact of Patient Involvement on Research 06:34 Personal Cancer Journeys 13:53 Future Goals for PIVOT 18:58 Encouraging Advocacy and Involvement 21:17 Conclusion and How to Get Involved Links from this Episode: ·       Learn more about PIVOT and how to join ·       Learn about Lynch Syndrome ·       Learn about oral cancer ·       Follow PIVOT on Instagram To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, speaks with Dr. Ronald Chen, chair of Radiation Oncology and associate director for Community Outreach and Engagement at KU Cancer Center. Dr. Chen shares his personal and professional journey from growing up in Topeka to Harvard and a career on the East Coast and back to Kansas, focusing on his motivation to return home and how his work impacts rural communities. He discusses his efforts in cancer care, telehealth and clinical trials, emphasizing the importance of bringing skills back to Kansas to improve local healthcare. 00:00 Introduction to Bench to Bedside 00:47 Meet Dr. Ron Chen 01:33 Dr. Chen's Educational Journey 03:41 Returning to Kansas 05:40 Advice for Young Kansans 07:19 Midwest Reflections 09:50 Addressing Rural Healthcare Challenges 12:35 Community Engagement and Partnerships 14:46 Balancing Clinical Care and Research 17:02 Future of Cancer Care at KU 19:30 Conclusion and Farewell Links from this Episode: ·       Learn more about Dr. Ronald Chen ·       Read this Q&A with Dr. Chen focused on eliminating health disparities ·       Learn more about community outreach and engagement at KU Cancer Center ·       Read about the Masonic Cancer Alliance To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by Dr. Anthony Sung and Dr. Jennifer Klemp, leaders in cancer survivorship research. They discuss their personal motivations, the importance of comprehensive survivorship care starting from diagnosis, and the innovative programs and research efforts at the KU Center for Survivorship and Patient-Oriented Research. The conversation highlights the challenges faced by cancer survivors, the need for individualized care, and the role of community support and research in improving survivor outcomes. The episode emphasizes KU Cancer Center's mission to become a national leader in patient-oriented survivorship care and research. 00:00 Introduction to Bench to Bedside 00:33 Exploring Cancer Survivorship 01:09 Personal Motivations in Cancer Research 04:21 Defining Cancer Survivorship 07:40 Vision for the KU Center for Survivorship and Patient Oriented Research 13:29 Future of Cancer Survivorship Research 26:45 Conclusion and Resources Links from this Episode: ·       Learn more about Dr. Anthony Sung ·       Learn more about Dr. Jennifer Klemp ·       Learn more about the KU Center for Survivorship and Patient-Oriented Research To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.  

In the season six premiere of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, sits down with his friend and colleague Dr. Gary Doolittle, medical director of the Masonic Cancer Alliance (MCA) and melanoma expert. Dr. Doolittle shares his personal and professional experiences in oncology, including his own cancer diagnosis and how it has influenced his approach to patient care. They discuss the unique challenges rural communities face in accessing cancer treatment and the role initiatives like the Masonic Cancer Alliance and telemedicine play in improving care accessibility. Dr. Doolittle offers insights from his dual perspective as a physician and a cancer survivor, emphasizing the importance of empathy, swift patient management and building trust in healthcare systems. 00:00 Introduction to Bench to Bedside 00:33 Meet Dr. Gary Doolittle 01:29 Dr. Doolittle's Personal Cancer Journey 03:01 Impact on Patient Care 06:36 Challenges in Rural Cancer Care 12:59 Telemedicine and the MCA 18:50 Advice for Patients and Physicians 21:33 Conclusion and Final Thoughts Links from this Episode: ·       Learn more about Dr. Gary Doolittle ·       Learn more about the Masonic Cancer Alliance ·       Learn more about the MCA's community outreach and engagement efforts For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, sits down with Dr. David Akhavan, a physician-scientist pioneering cell therapy research for brain cancer. Dr. Akhavan discusses the revolutionary potential of chimeric antigen receptor (CAR) T-cell therapy in treating cancers like glioblastoma, the complexities involved and the innovative approaches his team is employing, such as smarter engineered T-cells and nanoparticles. Highlighting the collaboration within KU Cancer Center, Dr. Akhavan also shares personal insights into his motivation and the future of cancer treatment. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Learn more about cell therapy at KU Cancer Center Learn more about brain cancer Read more about Dr. Akhavan's work on the KU Cancer Center blog, "Exploring Immunotherapy Treatments to Treat Brain Cancer" Learn about Head for the Cure Read how physician-scientists at KU Cancer Center bridge the gap between the laboratory and the clinic  

In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by two special guests: Paul Seyferth, a stage IV lung and prostate cancer survivor and creator of the Wall of Hope Project at KU Cancer Center, and Rebecca Keunen, clinical case manager lead at the cancer center and a cancer survivor herself. They discuss Paul's emotional journey through his diagnosis and the creation of the Wall of Hope installation, which features cancer patients' photos, videos and stories to inspire hope. Rebecca shares her involvement in the project and her perspective on the importance of personal connections in cancer care. Both guests offer valuable insights and advice for cancer patients and survivors, emphasizing the importance of strategic thinking and support systems in the survival journey. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Learn more about the Wall of Hope and view videos from participants Learn more about survivorship care at KU Cancer Center Find information about Paul's book, "Will to Live:  A Deep Survival Guide to stage IV Lung Cancer" Learn more about the Brandmeyer Patient Resource Center at KU Cancer Center

In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, sits down with Dr. Rebecca Whelan, an associate professor of chemistry at the University of Kansas and member of KU Cancer Center's Cancer Biology research program. The discussion focuses on the limitations of the CA125 blood test for ovarian cancer detection and Dr. Whelan's groundbreaking research, which reveals new insights into the structure of the CA125 protein. Dr. Whelan explains how new DNA sequencing technologies and artificial intelligence, specifically the Alpha Fold program, have helped her team improve the understanding and detection of ovarian cancer. Additionally, Dr. Whelan talks about collaborative efforts to identify new biomarkers for early diagnosis of ovarian cancer and shares advice for young scientists interested in making a difference in medicine through chemistry. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Learn more about Dr. Whelan's research into CA125 Learn more about ovarian cancer  Read about ovarian cancer screening and diagnosis at KU Cancer Center Learn more about Dr. Rebecca Whelan

In this episode of the Bench to Bedside podcast Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, discusses the critical topic of alcohol consumption and its link to cancer risk with Dr. Lauren Nye, medical oncologist at the cancer center and associate professor of Internal Medicine at the University of Kansas Medical Center. They delve into the recent advisory from the US Surgeon General highlighting the increased cancer risk associated with alcohol consumption, explore how alcohol can promote cancer development through various mechanisms, and offer practical advice for reducing alcohol intake. Dr. Nye underscores the importance of public awareness and the role of healthcare professionals in disseminating this information, while also emphasizing the need for sustainable lifestyle changes. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Read the US Surgeon General's Advisory "Alcohol and Cancer Risk" Read "Understanding Breast Cancer Prevention" by Dr. Lauren Nye on the KU Cancer Center blog Learn about cancer prevention and risk reduction on the KU Cancer Center website

In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by Dr. Lisa Harlan-Williams, associate director for education at the cancer center, to discuss the variety of careers involved in the field of cancer care and research, beyond doctors and nurses. Dr. Harlan-Williams shares her own career path and talks about various initiatives at KU Cancer Center to attract and train for the oncology workforce. They highlight the importance of early exposure to different career opportunities and the educational programs available, including shadowing professionals and summer research internships. The discussion also touches on the growing demand for cancer care professionals due to increasing cancer cases and workforce shortages. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Learn more about educational opportunities and programs for students considering a career in cancer research at KU Cancer Center Learn about the Accelerate Cancer Education summer research program at KU Cancer Center Read about the C-CLEAR summer internship program at KU Cancer Center Learn more about the Jewell Summer Research Training Program at KU Cancer Center    

In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, hosts Dr. Marc Hoffmann, associate professor specializing in Hematologic Malignancies and Cellular Therapeutics at the University of Kansas Medical Center and medical director of the lymphoma program at KU Cancer Center, where he also serves as medical director for quality improvement initiatives. Beyond his clinical expertise, Dr. Hoffmann has contributed significantly to research in lymphoma and chronic lymphocytic leukemia (CLL), and he actively participates in national cooperative group clinical trials. Dr. Hoffmann shares his career path into the field of oncology, innovations in lymphoma and CLL treatments, as well as the unique aspects of KU Cancer Center's lymphoma program. The conversation also covers Dr. Hoffmann's Peace Corps experience in West Africa, his involvement in clinical trials, and advice for medical students interested in hematology and oncology. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Learn more about the lymphoma program at KU Cancer Center Learn about chronic lymphocytic leukemia (CLL) Learn more about CAR T-cell therapy at KU Cancer Center Learn more about Dr. Marc Hoffmann Watch a video of Dr. Hoffmann explaining how blood cancer is diagnosed  

In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by Dr. Andrew Godwin, director of KU Cancer Center's Biospecimen Shared Resource. They discuss the critical role that volunteers who donate biospecimens play in advancing cancer research. The podcast delves into the types of biospecimens collected, their use in medical studies, and how the KU Cancer Center's repository has grown to include over one million samples. Dr. Godwin shares insights on successful projects, including the Triple Negative Breast Cancer Registry and emerging technologies in biomarker analysis. He also emphasizes the importance of community participation in the biobank and offers advice for young investigators in the field of biomedical research. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode:  Learn more about KU Cancer Center's Biospecimen Shared Resource Learn how to donate to the KU BioBank Read more about how the Biospecimen Shared Resource supports the Early Detection Program within the KU BioBank Learn more about Dr. Andrew Godwin

In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, engages in an insightful conversation with Dr. Robert Winn, Director and Lippman Chair in Oncology at Massey Comprehensive Cancer Center at Virginia Commonwealth University. They discuss Dr. Winn's pioneering work in cancer research and health equity, especially focusing on underserved communities. The episode highlights the significance of the Inclusive Excellence initiative Dr. Winn is leading as president of the American Association of Cancer Institutes (AACI), as well as disparities in cancer care in rural areas, the exciting advancements in immunotherapy and molecular therapies, and the essential role of trust and communication in healthcare. The dialogue underscores the critical need for appropriate investment in cancer research to continue making significant strides in reducing cancer mortality and improving patient outcomes. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at [email protected], and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Learn more about Dr. Robert Winn Read about the AACI Inclusive Excellence initiative Learn about the National Cancer Institute and the designated cancer centers program