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Send us a Text Message (please include your email so we can respond!) Episode 84! In this episode we finish up our discussion of the articles presented with the CCR Down Under Conference with ACTiVE (close loop ventilation) and CLIP2 (cryopreserved platelets for surgical bleeding). Both are neutral trials at best, so we took them both pretty short. ACTiVE: https://pubmed.ncbi.nlm.nih.gov/41361939/ ACTiVE (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2842610 CLIP2: https://pubmed.ncbi.nlm.nih.gov/41360717/ CLIP2 (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2842479 If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 83! Only one article this episode since Todd is feeling a little under the weather, but still a good discussion! ImmunoSep (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2842634 ImmunoSep (pubmed): https://pubmed.ncbi.nlm.nih.gov/41359996/ If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Back by popular demand, year in review! Or probably better titled "Our Favorite Articles of the Year" but I kept the title from last year. A smattering of papers and topics in this one ranging from avalanche survival, to intubation, to cardiac resuscitation and more.  Happy New Year everyone! We will see you in 2026, thanks for listening and spending sometime with us. If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 81! In this episode we talk to Yonathan Fruend the senior author on the MODS study looking at a single questions approach to ruling out pulmonary embolism in the emergency department. This is not our typical patient population but this is a good episode, don't miss this one! MODS: https://pubmed.ncbi.nlm.nih.gov/41135553/ If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) We start our Critical Care Reviews Down Under coverage with RSI talking with the first author of the "Ketamine versus Etomidate for Adults Receiving Emergency Endotrachael Intubation", Jonathan Casey! We will pick up the rest of our CCR Down Under Coverage after the holiday break! If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 79! We talk all about perfusion with arterial lines in EVERDAC and personalized resuscitation with ANDROMEDA SHOCK 2!  EVERDAC: https://pubmed.ncbi.nlm.nih.gov/41159885/ EVERDAC (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2502136 ANDROMEDA SHOCK 2: https://pubmed.ncbi.nlm.nih.gov/41159835/ ANDROMEDA SHOCK 2(JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840823 If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 78! We start our discussion of the trials that drop with ESICM with the much anticipated BICAR-ICU 2! Then we talk briefly about some changes to the SOFA score with the new SOFA-2 score.  BICAR-ICU2: https://pubmed.ncbi.nlm.nih.gov/41159812/ BICAR-ICU 2 (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840824 SOFA-2: https://pubmed.ncbi.nlm.nih.gov/41159833/ SOFA-2 (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840822 If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 77! We will start on ESICM coverage next episode. In this episode we talk about WFIT or "A Randomized Controlled Trial of a Post-ICU Telehealth Care Model" by Bakhru et al published in the blue journal September 2025! A long discussion but a good one! WFIT: https://pubmed.ncbi.nlm.nih.gov/40532205/ Editorial: https://pubmed.ncbi.nlm.nih.gov/40700738/ ICU Recovery Pilot: https://pubmed.ncbi.nlm.nih.gov/31385881/ If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) We were LIVE from the CHEST Annual Meeting 2025! Thanks to everyone who came out and stuck around to chat afterwards. We cover a lot of ground including some conference and Chicago related banter (~8 minutes if you wanted to skip to the learning!) High frequency oscillation: https://pubmed.ncbi.nlm.nih.gov/40983167/ MELLOW: https://pubmed.ncbi.nlm.nih.gov/39800236/ Continuous glucose monitoring: https://pubmed.ncbi.nlm.nih.gov/39956190/ SAFE-ECMO: https://pubmed.ncbi.nlm.nih.gov/40081660/ BASE: https://pubmed.ncbi.nlm.nih.gov/39971001/ If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 75! We talk about melatonin! We highlight MELLOW because it has the best acronym (by Burry et al in CHEST 2025). Then we dive into our mailbag! MELLOW: https://pubmed.ncbi.nlm.nih.gov/39800236/ DEMEL: https://pubmed.ncbi.nlm.nih.gov/40608082/ Meta-analysis: https://pubmed.ncbi.nlm.nih.gov/40662882/ If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 74! We talk about the history and current practice of SBTs with "Providers Consistently Delay Extubation After Successful Spontaneous Breathing Trials" by Barker et al in Annals of the ATS and the original 1996 SBT article by Ely et al in NEJM. SBT: https://pubmed.ncbi.nlm.nih.gov/8948561/ SBT (NEJM): https://www.nejm.org/doi/10.1056/NEJM199612193352502 SBT Timing: https://pubmed.ncbi.nlm.nih.gov/40393063/ SBT Timing (Annals ATS): https://www.atsjournals.org/doi/10.1513/AnnalsATS.202502-188OC If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) We are (were) LIVE at ACNP Critical Care Bootcamp 2025! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the PIC trial or "Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia" by Lemiale et al published in the Lancet Respiratory Medicine September 2025 PIC (pubmed): https://pubmed.ncbi.nlm.nih.gov/40652952/ PIC (LRM): https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00125-0/abstract If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 72! We continue talking about the articles from the CCR25 conference with UK-ROX or "Conservative Oxygen Therapy in Mechanically Ventilated Critically Ill Adult Patients" published in JAMA 2025 by Martin et al and TARGET-Protein or "Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit" by Jaber et al in Lancet 2018. UK-ROX: https://pubmed.ncbi.nlm.nih.gov/40501321/ UK-ROX (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2835384 TARGET-Protein: https://pubmed.ncbi.nlm.nih.gov/40495743/ TARGET-Protein (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2835302 If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 71! We continue talking about the articles from the CCR25 conference with FLUID or "A Crossover Trial of Hospital-Wide Lactated Ringer's Solution versus Normal Saline" published in NEJM 2025 by McIntyre et al and our old article is BICAR-ICU or "Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit" by Jaber et al in Lancet 2018. FLUID: https://pubmed.ncbi.nlm.nih.gov/40503714/ FLUID (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2416761 BICAR-ICU: https://pubmed.ncbi.nlm.nih.gov/29910040/ If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!) Episode 70! In this episode we have a special guest, Wes Ely, join us to talk about A2B or "Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients" by Walsh et al published in JAMA May of 2025. A long discussion but a good one, don't miss this one! Pubmed: https://pubmed.ncbi.nlm.nih.gov/40388916/ JAMA: https://jamanetwork.com/journals/jama/article-abstract/2834276 Editorial: https://jamanetwork.com/journals/jama/article-abstract/2834277 If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!