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Welcome to the October 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the October 2026 issue of Diabetes. 7:20 First, Kirk welcomes Jia Liu and Zhenqi Liu, MD, both of the Division of Endocrinology and Metabolism at the University of Virginia School of Medicine. Their article, "GIP Acutely Blunts Insulin- and GLP-1–Induced Muscle Microvascular Perfusion," is available for free at doi.org/10.2337/db25-1009. 30:45 Next, Darleen speaks with Clay F. Semenkovich, MD, Chief of the Division of Endocrinology, Metabolism, and Lipid Research at Washington University in St. Louis, and Guifang Dong, PhD, instructor in medicine, also at Washington University. Their article, "Adipose Tissue Palmitoylation Cycling Mediates Insulin Resistance and Preservation of β-Cell Function in Mice," is available at doi.org/10.2337/db26-0023. 53:25 In the latest edition of "Sweet Talk," our hosts are joined by Michael Schwartz, MD, Robert H. Williams Endowed Chair in Medicine Professor of Medicine in the Division of Metabolism, Endocrinology and Nutrition at the University of Washington. Dr. Schwartz's work has helped shape how we think about the brain's role in regulating food intake, body weight, and blood glucose control. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the September 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the September 2026 issue of Diabetes. 9:55 First, Kirk welcomes Daniel Ferguson, PhD, and Sandip Mukherjee, PhD, both of the Division of Nutrition Science and Obesity at Washington University in St. Louis. Their article, "Adipose Tissue Overexpression of Nicotinamide Phosphoribosyltransferase Prevents Metabolic Dysfunction in Obese Mice via Extracellular Vesicles", is available for free at doi.org/10.2337/db25-0914. 37:55 Next, our hosts speak with Subhasmita Rout, doctoral student, and Ran Hee Choi, both of the Department of Nutrition and Integrative Physiology at the University of Utah College of Health. Their article, "Females Are Completely Resistant to Semaglutide-Induced Muscle Loss in ob/ob Mice", is available for free at doi.org/10.2337/db26-0229. 1:03:35 In honor of National Childhood Obesity Awareness Month, the latest "Sweet Talk" features three guests who speak to the infrastructure needed to advance the study, care, and treatment of those living with obesity and diabetes. Anthony Ferrante, MD, PhD, is co-director of the New York Nutrition Obesity Research Center at Columbia University, Darrell Neufer, PhD, directs the North Carolina Diabetes Research Center at East Carolina University, and Theresa Strong, PhD, is Director of Research Programs at the Foundation for Prader-Willi Research. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the August 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the August 2026 issue of Diabetes. This special episode will highlight articles from the Diabetes Symposium, "Non-Classical Complications of Diabetes: Epidemiology, Mechanism, Treatment," presented at the 86th Scientific Sessions in New Orleans. 7:10 First, Kevin welcomes John Ussher, PhD, of the University of Alberta. His article, "Focusing on Diastolic Dysfunction to Achieve Consensus With the Term Diabetic Cardiomyopathy," is available for free at doi.org/10.2337/dbi26-0002. 35:00 Next, our hosts welcome Norbert Stefan, MD, PhD, an endocrinologist with the University Hospital in Tübingen, Germany. His article, "MASLD as Complication of Diabetes," is available for free at doi.org/10.2337/dbi26-0001. 1:06:25 Finally, our hosts speak with Julia A. Critchley, PhD, MPH Tess Harris, MD, MSc and Liza Bowen, PhD, MSc, all of City St. Georges University of London. Their article, "Increased Risk of Infections in People Living With Diabetes," is available for free at doi.org/10.2337/dbi26-0004. Listeners can watch these symposium talks on demand at ADA.org. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

In this special crossover episode, recorded live at the American Diabetes Association's Scientific Sessions in New Orleans, the hosts of the ADA's professional podcasts—DOC Updates, Diabetes Care "On Air", DiabetesBio, and The Points of CARE—come together to discuss key highlights and groundbreaking research presented at the 2026 meeting. They share expert insights across the bench-to-bedside spectrum, including basic science, clinical research, and the latest in diabetes care and education. Tune in for thoughtful reflections on what this year's findings mean for clinical practice and future research. Available now across all ADA professional podcast channels. Featured Podcasts: DOC Updates – ADA's podcast for primary care Diabetes Care "On Air" – From ADA's clinical research journal, Diabetes Care DiabetesBio – From ADA's flagship research journal, Diabetes The Points of CARE - The official podcast of Diabetes, Obesity, and CardioMetabolic CARE Join the Discussion with: Alice Cheng, MD – Co-host of Diabetes Care "On Air" Kirk Habegger, PhD – Co-host of DiabetesBio Michael Rickels, MD, MS – Co-host of Diabetes Care "On Air" Neil Skolnik, MD – Co-host of DOC Updates and Diabetes Day by Day Kevin Williams, PhD – Co-host of DiabetesBio Richard Beaser, MD – Co-host of The Points of CARE 🔗 Learn more about ADA's full podcast portfolio: https://diabetesjournals.org/journals/pages/podcasts Subscribe to DOC Updates, Diabetes Care "On Air", DiabetesBio, and The Points of CARE on Apple Podcasts, Amazon Music, Spotify, or your preferred platform.

Welcome to the July 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the July 2026 issue of Diabetes. 5:40 Kirk welcomes Jennifer Thompson, PhD, Associate Professor in the Department of Biochemistry and Molecular Biology at the University of Calgary, and Taylor Scheidl, a doctoral student in Thomson's lab. Their article, "Estrogen Mediates Capacity for Hyperplastic Adipose Expansion and Preserves Adipose Progenitor Cell Availability in Subcutaneous Depots of Female Mice," is the latest Paper of the Month, and available for free at doi.org/10.2337/db25-0773. 36:20 In the latest edition of "Sweet Talk," our hosts speak with Jeffrey Zigman, MD, PhD, Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Endocrinology. Dr. Zigman, who has type 1 diabetes himself, has spent his career studying ghrelin as a hormone to regulate food intake, body weight, blood glucose regulation, and many other aspects of metabolism. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the June 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the June 2026 issue of Diabetes. 7:00 To discuss this issue's Paper of the Month, our hosts speak with Alyssa Hasty, PhD, Vice Provost and Senior Associate Dean of Faculty Affairs at UT Southwestern in Dallas, and Jamie Garcia, PhD, Associate Director for Scientific Partnerships and Engagement at Jane Coffin Childs Memorial Fund for Medical Research. Their article, "Interrupting T-Cell Memory Ameliorates Exaggerated Metabolic Response to Weight Cycling," is available for free at doi.org/10.2337/db25-0605. 27:35 Next, Darleen is joined by Randy J. Seeley, PhD, Henry King Ransom Professor of Surgery and Professor of Internal Medicine and Nutritional Sciences at the University of Michigan School of Medicine, as well as Nadejda Bozadjieva Kramer, PhD, Assistant Professor of Surgery at the University of Michigan School of Medicine. Their article, "Gut-Derived FGF15 Modulates Lean Mass, Bone, and Bile Acid Responses to Weight Loss," is available for free at doi.org/10.2337/db25-0466. 57:40 In the latest edition of "Sweet Talk," our hosts speak with Martin Myers, MD, PhD, Marilyn H Vincent Professor of Diabetes Research at the University of Michigan, Director of the Elizabeth Caswell Diabetes Institute, and recipient of the 2010 Outstanding Scientific Achievement Award from the American Diabetes Association. They talk about his work in leptin receptor signaling and the way brain circuitry works alongside GLP-1 based drugs to induce weight loss. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the May 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the May 2026 issue of Diabetes. 6:45 Our hosts speak with Sushant Bhatnagar, PhD, an associate professor in the Division of Endocrinology, Diabetes, and Metabolism in the Department of Medicine at the University of Alabama at Birmingham. He is corresponding author of May's Paper of the Month, "Tomosyn-2 Regulates Postnatal β-Cell Expansion and Insulin Secretion to Maintain Glucose Homeostasis," available for free at doi.org/10.2337/db25-0644. 30:45 Next, Darleen is joined by Vladimer Darsalia, PhD, a docent in neuroscience in the Department of Clinical Science and Education at the Karolinska Institute in Solna, Sweden. He is co-corresponding author of the article "Normalization of Insulin Resistance Rather Than Hyperglycemia Before Stroke Improves Functional Outcomes in a Mouse Model of Type 2 Diabetes," available for free at doi.org/10.2337/db25-0532. 48:30 In the latest edition of "Sweet Talk," our hosts speak with Dr. Timo Mueller, Director of the Institute for Diabetes and Obesity at Helmholtz in Munich and professor at the Walter Straub Institute for Pharmacology and Toxicology at Ludwig Maximilian University of Munich. Mueller is the current recipient of the American Diabetes Association's Outstanding Scientific Achievement Award for his work with brain GIP receptors, crucial for understanding the functionality of GLP-1s. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the April 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the April 2026 issue of Diabetes. 5:30 Our hosts speak with Valeria Fabriciova, a PhD student in the group of Gabriela Pavlinkova, PhD, DSc, laboratory head at the Institute of Biotechnology at the Czech Academy of Sciences in Prague. They are co-authors of the article, "ISL1 Restricts Progenitor Programs and Promotes β-Cell Maturation, Revealing Sex Differences in Diabetes Progression," available for free at doi.org/10.2337/db25-0673. 40:00 Next, Darleen is joined by Beatriz Delgado-Corrales, a postdoctoral fellow in the lab of Ki Wook Kim, PhD, senior lecturer and principal investigator at the University of New South Wales in Sydney, Australia. They are the authors of "Distinct Enterovirus Antigen Landscape in Children With Islet Autoimmunity," available for free at doi.org/10.2337/db25-0805. 1:07:35 In the latest edition of "Sweet Talk," Kevin and Darleen speak with Lora K. Heisler, PhD, Chair in Human Nutrition and Head of the Obesity and Food Choice Division of the Rowett Institute at the University of Aberdeen, Scotland. Dr. Heisler was also the recipient of the 2018 Outstanding Scientific Achievement Award from the American Diabetes Association for her work on harnessing brain circuits to improve type 2 diabetes. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the March 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the March 2026 issue of Diabetes. 8:15 Kirk speaks with Matthew Merrins, PhD, Joseph F. Hoffman Professor of Cellular and Molecular Physiology at Yale School of Medicine. He is senior author on the article "Amino Acid Sensing by the α-Cell Mitochondrial Phosphoenolpyruvate Cycle Regulates Intracellular Ca2+Levels Without Affecting Glucagon Secretion," available at doi.org/10.2337/db25-0510. 29:25 Next, Darleen is joined by Noah Levi, an MD-PhD student in the group of Alejandro Caicedo, PhD, professor in the Division of Endocrinology, Diabetes and Metabolism, Department of Medicine at the University of Miami Miller School of Medicine. They are corresponding authors of the article "Activating Muscarinic Receptor Signaling in Intrapancreatic Neurons Is Required for Parasympathetic Cholinergic Control of Pancreatic Cell Function," available at doi.org/10.2337/db25-0604. 51:20 In the latest edition of "Sweet Talk," Kevin speaks with Mark Atkinson, PhD, about the American Diabetes Association's annual conference, Scientific Sessions. Atkinson is Eminent Scholar for Diabetes Research at the University of Florida and chair of the Scientific Sessions Programming Committee. More information about this year's Scientific Sessions, taking place June 5-8 in New Orleans, is available at professional.diabetes.org/scientific-sessions. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the February 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2026 issue of Diabetes. 6:10 To discuss this issue's Paper of the Month, our hosts are joined by authors Christopher Wilson, PhD and Daniel J. Moore, MD, PhD, both of Vanderbilt University. Their article, "B Lymphocytes Impede Tregs to Erode Islet Tolerance in Type 1 Diabetes," is available for free at doi.org/10.2337/db25-0241. 37:05 Next, Darleen speaks with Bettina Mittendorfer, PhD. Dr. Mittendorfer is Senior Associate Dean for Research and Director of NextGen Precision Health, Clinical and Translational Science Unit at the University of Missouri and the lead author of "Effects of Marked Weight Loss Induced by Gastric Bypass Surgery or Low-Calorie Diet Alone on Postprandial Glucose Disposal in Type 2 Diabetes," available for free at doi.org/10.2337/db25-0737. 56:00 In the latest edition of "Sweet Talk," Kevin introduces Sir Stephen O'Rahilly, a clinical scientist at the University of Cambridge and past recipient of the American Diabetes Association's Banting Medal for Scientific Achievement. They discuss O'Rahilly's career, which reshaped scientists' understanding of metabolism and metabolic disease. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the January 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the January 2026 issue of Diabetes. 17:40 After sharing their predictions for the new year, our hosts are joined by Masaya Oshima, PhD, a contract researcher at Institut Cochin in Paris, France. He is the lead author on the January Paper of the Month, "Killing of Human β-Cells by CD8+ T Cells Triggers Inflammatory Paracrine Signaling and Neighboring β-Cell Dysfunction," available for free at doi.org/10.2337/db25-0473. 33:10 In the latest edition of "Sweet Talk," Kevin speaks with Sarah Stanley, MBBCh, PhD, an associate professor at the Icahn School of Medicine at Mount Sinai in New York and recipient of the American Diabetes Association's Pathway to Stop Diabetes Award. Her article, "Neural Regulation of Blood Glucose in Acute Stress: A Report on Research Supported by Pathway to Stop Diabetes," is available for free at doi.org/10.2337/dbi24-0051 To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the December 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the December 2025 issue of Diabetes. 13:10 After discussing their favorite interviews of the past two years, our hosts are joined by Bryan Bergman, PhD, a professor in the Division of Endocrinology, Metabolism, and Diabetes at the University of Colorado Anschutz Medical Campus. He is the corresponding author of "Combined Weight Loss and Exercise Training Alters Skeletal Muscle Subcellular Lipid Localization and Intermuscular Adipose Tissue Cellular Composition," a featured article in this month's issue. The article is available for free at doi.org/10.2337/db25-0492. 35:25 To discuss the latest Paper of the Month, our hosts are joined by authors Kathryn Walters, PhD, postdoctoral researcher at CU Anschutz, Roberto Castro-Gutierrez, PhD, a postdoctoral fellow at the University of California San Francisco, Neelanjan Mukherjee, PhD, Assistant Professor in the Department of Biochemistry and Molecular Genetics at the CU Anschutz, and Holger Russ, PhD, Associate Professor in the Department of Pharmacology and Therapeutics at the University of Florida. Their article, "Proteogenomic Discovery of Novel Open Reading Frames With HLA Immune Presentation on Human β-Cells," is available for free at doi.org/10.2337/db24-0527. 1:00:50 In the latest edition of "Sweet Talk," Kevin and Kirk explore how new technologies shape the ways we assess metabolism. They are joined by Alexander Banks, PhD, Director of the Energy Balance core facility at Beth Israel Deaconess Medical Center (BIDMC) at Harvard Medical School, Corey Holman, PhD, Technical Director of the Rodent Metabolic Phenotyping Core at the University of Pennsylvania, and Louise Lantier, PhD, Metabolic Pathophysiology Core Managing Director at Vanderbilt University Medical Center. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the November 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the November 2025 issue of Diabetes. 6:00 In the first segment, our hosts are joined by Kaylia Reynolds, MS and Nora Franceschini, MD, MPH, FAHA, both of the Department of Epidemiology at the Gillings School of Global Public Health at the University of North Carolina. Their paper, "Diabetes Genetic Clusters and Clinical Outcomes in American Indians," is available for free at doi.org/10.2337/db25-0322. 20:40 To discuss the latest Paper of the Month, our hosts are joined by first author Stephanie K. Holm, a postdoctoral student in the Clemmensen group, and Christoffer Clemmensen, Associate Professor in the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen. Their paper, "Sustained Weight Loss With Combined LEAP2 and Semaglutide Treatment in Mice," is available for free at doi.org/10.2337/db24-1056. 38:15 In the latest edition of "Sweet Talk," Kevin and Kirk speak with Banting Medal recipient Jens Juul Holst, MD, DMSc, of the University of Copenhagen, whose work with incretin hormones laid the foundation for therapies now used around the world. His article, "Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture," is available for free at doi.org/10.2337/dbi21-0026. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the October 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the October 2025 issue of Diabetes. 5:50 In the first segment, our hosts are joined by Tessa M. Cacciottolo, PhD, a Chain Florey TTI Fellow in the MRC Laboratory of Medical Sciences at Imperial College London. She is the first author of the article "Glucagon Receptor Deficiency Causes Early-Onset Hepatic Steatosis," available for free at doi.org/10.2337/db25-0209. 22:15 In honor of last month being Childhood Obesity Month, in this month's edition of "Sweet Talk", our hosts speak with Kristen Nadeau, MD, MS, a professor of pediatrics at the University of Colorado Anschutz Medical Campus, and Bethany Cartwright, MD, PhD, an Assistant Instructor in the Department of Pediatrics at UT Southwestern Medical Center. They discuss the complications children with obesity can face, as well as the stigma and weight biases that accompany these diagnoses. Cartwright's article, "Adipose Tissue as a Target for Precision Medicine Approaches in Childhood Obesity," is available for free at doi.org/10.2337/dbi24-0044. 49:10 In a special segment, Nadeau and Cartwright take questions directly from kids of various ages on the topics of diabetes and obesity. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the September 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the September 2025 issue of Diabetes. 5:25 In the first segment, our hosts are joined by Carmelo Quarta, PhD, a principal investigator at INSERM (National Institute of Health and Medical Research) and a group leader at the Bordeaux Neurocampus at the University of Bordeaux in France. He is the co-corresponding author of "GLP-1–Mediated Targeting of Inflammation Corrects Obesogenic Memory in Male Mice," available for free at doi.org/10.2337/db24-1071. 27:30 Next, Darleen and Kirk speak with Willa A. Hsueh, MD, Professor of Medicine in the Division of Endocrinology at the Ohio State University College of Medicine. She is a corresponding author on this month's Paper of the Month, "The GLP-1 Receptor Agonist Dulaglutide Attenuates Hepatic Steatosis in Obesity via a Weight-Independent Mechanism," available for free at doi.org/10.2337/db24-0861. 46:20 Lastly, in this month's edition of "Sweet Talk," Kevin and Darleen are joined by Alexander R. Nectow, MD, PhD. A recipient of the American Diabetes Association's Pathway to Stop Diabetes Award, Dr. Nectow lab at Columbia University studies the dorsal raphe nucleus (DRN) and its relation to metabolism. His article, "The Dorsal Raphe Nucleus and the Integrative Control of Feeding: A Report on Research Supported by Pathway to Stop Diabetes," is available for free at doi.org/10.2337/dbi24-0015. To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!