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Barbara Peng spent years running one of the most recognizable brands in business media. Newly out of the CEO seat at Business Insider, she joins Rapid Response for a candid conversation about the state of journalism, the future of trust, and what leaders in every industry need to understand about operating in an AI world. She reflects on her tenure at Business Insider — the pivot back to the brand’s core, the layoffs, the AI-powered paywall that actually worked — and makes the case that media’s resistance to AI isn’t a journalism problem, it’s a business problem. Peng also lands on the insight that may be the most important thing any leader needs to hear right now: it doesn’t matter how fast the technology moves if your organization is too afraid to experiment with it. The sweet spot isn’t the capability. It’s the rate of digestion. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Renee Wegrzyn spent her career building the future of American science — including ARPA-H, the White House agency created to accelerate health breakthroughs. Then the Trump administration showed her the door. Wegrzyn co-founded Transfyr to tackle what she calls one of the most overlooked issues in science: the magic hands problem. She joins Rapid Response to explain why fixing this unglamorous bottleneck is the prerequisite for everything AI promises to deliver in medicine, what the federal funding cuts are really costing science, and why she can feel the next Sputnik moment coming — even if she can’t quite name it yet. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode of Rapid Response first aired in 2025. Live on stage at Masters of Scale Summit in San Francisco, Airbnb co-founder and CEO Brian Chesky explores what role business could and should play in building the future. He shares his candid perspective on politics, creativity, and AI — taking listeners from Airbnb’s humble beginnings to bold plans for the company’s future. Through a designer’s lens, Chesky also reveals the single question leaders must ask themselves, and explores how best to make tricky decisions in a volatile climate.  For more conversations like this, join us at this year’s Masters of Scale Summit, coming up October 20-22 in San Francisco. Visit the Rapid Response website here: rapidresponseshow.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Prediction markets incentivize truth. Everything else incentivizes clickbait. That's the core argument Luana Lopes Lara makes for Kalshi — the prediction market platform she co-founded that has gone from $5 billion to $22 billion in valuation in under a year, and is now being sued by New York's attorney general for $36 billion. Luana joins Rapid Response to make the case that Kalshi is fundamentally different from DraftKings — even though 75% of its volume is sports — explain why George Santos got banned for trying to trade on his own congressional attendance, and share what Kalshi's data actually says about the midterms. Plus the Timothée Chalamet dentist-chair ad, what ballet taught her about running a company, and what it's actually like to become the world's youngest self-made female billionaire. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What happens when you interview an AI? Bob Safian found out, and while it didn't break out into Cantonese, it was stranger than he expected. This episode is split in two: first, a conversation with Eline van der Velden, the Dutch actress-turned-tech-founder who created Tilly Norwood, the AI "actor" who sent Hollywood into a spiral. Then, Bob sits down with Tilly itself. Eline explains how a personal art project became one of the most controversial figures in entertainment — attracting talent agency interest, death threats, and a global debate about whether AI will kill acting or democratize it. She makes the case that great storytelling still requires human craft, and that the most dangerous thing anyone can do right now is stick their head in the sand. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The second a brand like Hershey stops being culturally relevant, says its CEO Kirk Tanner, you should be worried. He joins Rapid Response to explain exactly what he's doing to make sure that never happens. Tanner also reveals why GLP-1 users are actually good for the candy business, how AI is now routing Hershey's sales force in real time through Target and Walmart, and why the Reese's Oreo collaboration (which generated $100 million in its first five months) is the model for how iconic brands find new energy. And with a major Hollywood film about Milton Hershey coming this fall, he talks about whether this is Hershey's Barbie moment. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode of Rapid Response first aired in 2025. Live on stage at Masters of Scale Summit in San Francisco, Patagonia CEO Ryan Gellert and Chobani CEO Hamdi Ulukaya joined the New York Times’ David Gelles to explore the intersection of values and commerce. They reveal their different strategies for dealing with an activist White House, the pressure for what David calls “anticipatory compliance,” and how they grew their businesses while also prioritizing causes like environmental conservation and immigration. The pair also shared personal stories that mark key inflection points for their companies, and what most gives them hope for the future. For more conversations like this, join us at this year’s Masters of Scale Summit, coming up October 20-22 in San Francisco. Go to masters of mastersofscale.com/summit to learn more. Visit the Rapid Response website here: rapidresponseshow.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The world has never faced so many humanitarian crises at once, and the systems built to respond to them are fraying. Tjada McKenna, CEO of Prosper Global — the organization long known as Mercy Corps — joins Rapid Response during UN General Assembly week to share what she's seeing firsthand from Syria to Sudan to Ukraine to Gaza, and why she rebranded a 40-year-old institution in the middle of a funding crisis rather than in spite of one. She explains how the Strait of Hormuz conflict is quietly writing next year's food shortages into fragile countries right now, why Russia's playbook of attacking civilian infrastructure has spread to conflicts around the world, and what she's asking AI companies to do that no one has figured out yet.  Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For nearly two decades, Amy Webb's annual Tech Trends Report was required reading for anyone trying to keep up with technology. But this year, Webb killed the report and replaced it with something more applicable for leaders in an AI era. In this episode, CEO of Future Today Strategy Group Amy Webb joins Pioneers of AI host Rana el Kaliouby to unpack her 2026 Convergence Outlook and examines how AI-driven convergences such as compute shock, living intelligence, and emotional outsourcing will reshape business and daily life. Learn more about Pioneers of AI: http://pioneersof.ai/ Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Own or be owned. That's Codie Sanchez's ultimatum for anyone serious about their financial future. The founder of Contrarian Thinking and author of the new book Own or Be Owned returns to Rapid Response to make her most impassioned case yet for why buying a small business is the most reliable path to wealth that most people are too scared to take. She breaks down what "cowboying" your business is costing you, and why AI isn’t a shortcut for everyone, but instead an accelerator for what's already inside you. Plus, the industries she'd invest in right now, and why most small business owners are solving the wrong problems. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

AI isn't simplifying your life… Yet. It's mass-producing more options, more decisions, and more noise. Axios CEO Jim VandeHei returns to Rapid Response to make the case that the antidote isn't a better productivity app, it's a ruthless, three-part system he calls Confront, Delete, Amplify. VandeHei shares what he's learned from running Axios by these principles, including calling a leadership meeting with the subject heading "Let's Kill S***," and why he shuttered the Axios app despite years of internal resistance. He also reveals his candid read on the midterms and what they mean for business, the data center backlash he thinks could reshape the political landscape, and what's really at stake in Axios's OpenAI content deal.  Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On built a $4 billion sports brand in 16 years with a garden hose, a Roger Federer dinner in Zurich, and a young designer who watched a Halloween YouTube video. Co-founder and co-CEO David Allemann joins Rapid Response to explain why the defining decade for On is still ahead, and why being the most premium brand matters more than being the biggest. He breaks down the leadership shake-up that brought him back into a CEO role, and what the first-of-its-kind LightSpray robotic process says about On’s innovation philosophy. Allemann also makes the case for why the "movement class" is replacing the leisure class as the defining consumer of our time. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The NFL is the world's most valuable sports business, and it keeps growing. But is the growth sustainable? Sports journalist Michele Steele joins Rapid Response to kick off the 2026-2027 NFL season with a clear-eyed look at what's driving record franchise valuations, why quarterback salaries keep exploding, and what the league's dizzying array of streaming platforms means for the fans. She also breaks down the NFL's deliberate "Helmets Off" strategy to grow its female audience, the business calculus behind nine international games this season, and whether the Bears are really leaving Chicago. Plus the uncomfortable CTE question that won't go away: Is the sport actually safer or have fans been sold a story? Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jesse Cole loved baseball. He also knew most people thought it was too long and boring. So he disrupted America’s pastime by putting on a yellow tux - and an incredible show. In this episode of Masters of Scale, the founder of the Savannah Bananas welcomed host Jeff Berman to Anaheim Stadium before a show recently to talk about how he’s scaling Fans First Entertainment into a growing league that sells out pro sports stadiums all over the country. Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For decades, e-commerce rewarded the biggest brands that could buy their way to the top of search results. AI is changing that. Shopify COO Jess Hertz joins Rapid Response to share what Shopify's data reveals about the agentic shopping revolution in real time, and how the company is building the infrastructure layer that makes products discoverable and purchasable by AI. Plus, why Shopify's engineers can spend freely on AI tokens while the rest of the business world agonizes over ROI, and what it looks like when a company powering over 14% of online shopping decides to win the future or die trying. Visit the Rapid Response website here: https://www.rapidresponseshow.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.