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Age of Aging

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Rating
★★★★★
5
from
19 reviews
This podcast has
33 episodes
Language
English
Explicit
No
Date created
2024/07/15
Latest episode
2026/01/27
Average duration
37 min.
Release period
17 days

Description

Welcome to the Age of Aging, a podcast about living well with an aging brain. The Age of Aging is a podcast released every other Tuesday, covering a wide range of stories in aging research. Co-hosted by Jake Johnson and Terrence Casey from the Penn Memory Center communications team, each episode they will explore what it means to age with independence and dignity in the modern world. You can expect to hear from the University of Pennsylvania’s world-class researchers, caregivers of those with cognitive difficulties, and everyday people who want to keep their brain as healthy as possible as they age. The Age of Aging is produced by the Penn Memory Center and made possible by generous support from the Michael Naidoff Communications Hub fund.

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What Do You Wish People Understood More about Aging?
2026/01/27
In season 4 of the Age of Aging, we decided to end every interview with the same question: what do you wish people understood more about aging?     In this special bonus episode of the podcast, we share some of their answers. They remind us of the prevalence of ageism, the many benefits of old age, and that we always have the ability to grow and change at any age.      Special thanks this episode to Lucy Davenport, Andrew Borba, Amanda Lee Williams, James Bonas, Tracey Leigh, Leo Marks, Jennifer Craft Morgan, PhD, Bruce Miller, MD, Leah Lawler, Candace Kemp, PhD, and Jake Broder.   The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Dalia Elsaid, Jason Karlawish, Emily Largent, and Alison Lynn. The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsors, the TIAA Institute and Rothkoff Law Group. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging.    Caring for an aging loved one isn’t easy — but you don’t have to do it alone. At Rothkoff Law Group, we guide families across New Jersey and Pennsylvania through every stage of your aging journey. Our team of elder care attorneys, geriatric care coordinators, and public benefits specialists advocate for your loved one’s well-being and your peace of mind. Rothkoff Law Group — your partner in advocacy and senior care planning, every step of the way. Visit RothkoffLaw.com.     
Rx for Alzheimer's
2026/01/13
The year 2025 was full of breakthroughs, debates, and big questions in Alzheimer’s research. One event that shaped many of these conversations? The Clinical Trials on Alzheimer’s Disease (CTAD) Conference. It may not have been on everyone’s radar, but its impact was undeniable.    In this special episode, Penn Memory Center Co-Directors Dr. Jason Karlawish and Dr. David Wolk share what stood out at CTAD, what’s changing in the field, and what to watch next.    Inside this episode:  Anti-amyloid therapies update: Where things stand with lecanemab and donanemab, and what the next generation of these drugs could look like   GLP-1 disappointment: Why Novo Nordisk’s semaglutide trials for Alzheimer’s disease came up short   Lifestyle interventions: The latest findings from the POINTER Study and what they mean for brain health  Resources available on the episode webpage linked below  Visit CTAD’s website  More information on anti-amyloid therapies  Novo Nordisk’s announcement of negative results “EVOKE” and “EVOKE+” trials  More information on the POINTER Study     Special thanks this episode to Jason Karlawish, MD and David Wolk, MD.  The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.    The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsors, the TIAA Institute and Rothkoff Law Group. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging.    Caring for an aging loved one isn’t easy — but you don’t have to do it alone. At Rothkoff Law Group, we guide families across New Jersey and Pennsylvania through every stage of your aging journey. Our team of elder care attorneys, geriatric care coordinators, and public benefits specialists advocate for your loved one’s well-being and your peace of mind. Rothkoff Law Group — your partner in advocacy and senior care planning, every step of the way. Visit RothkoffLaw.com. 
A Disease's Final Kiss
2025/12/23
Art that tries to teach you things “stinks,” says playwright and actor Jake Broder.  “And yet there is a profound need for education, for awareness, for reducing stigma, for supporting the community and for medical education,” he said. A few years ago, while writing his latest play about the two individuals with frontotemporal dementia, he wrestled with how he could do both.  In the season 4 finale of the Age of Aging, we tell the story of UnRavelled, a play about perseverance through neurodegeneration, burgeoning creativity late in life and an artistic relationship across time. Producer Jake Johnson shares his first-hand experience of the play’s premiere and how it combined theater with community outreach and education.  What’s inside:   A historical perspective on composer Maurice Ravel’s brain condition and his work, “Bolero.”  An explanation from Dr. Bruce Miller on the relationship between frontotemporal degeneration and creativity.   Jake Broder’s insight into the inspiration and creation of the play as well as the associated Brain Health Festival.  The perspective of the show’s director and cast on creating the play and its core themes.  Resources available on the episode webpage linked below   Listen to Maurice Ravell’s Bolero  Learn more about Dr. Bruce Miller  Listen to Unraveling Bolero (Radiolab)  Learn more about Jake Broder  More information on For Their Thoughts Foundation  Visit the official website of UnRavelled   Subscribe to the Age of Aging Newsletter    Special thanks this episode to Dr. Bruce Miller, Jake Broder, Betsy Hall, Lucy Davenport, James Bonas, Leo Marks, Tracy Leigh, and the entire UnRavelled team.  The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.    The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsors, the TIAA Institute and Rothkoff Law Group. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging.    Caring for an aging loved one isn’t easy — but you don’t have to do it alone. At Rothkoff Law Group, we guide families across New Jersey and Pennsylvania through every stage of your aging journey. Our team of elder care attorneys, geriatric care coordinators, and public benefits specialists advocate for your loved one’s well-being and your peace of mind. Rothkoff Law Group — your partner in advocacy and senior care planning, every step of the way. Visit RothkoffLaw.com.         
Yes And...
2025/12/09
If you asked most caregivers, they would probably say there’s nothing funny about caring for someone with dementia. The stress, grief, and frustration can feel overwhelming. But what if the principles of improv comedy — being present, saying “yes,” and working together — could make caregiving easier and more joyful?  In this episode of the Age of Aging, we explore the surprising connection between improv and dementia care. You’ll hear how techniques from the stage are helping caregivers reduce stress, improve communication, and find moments of joy.  What’s inside:   A peek inside the Penn Memory Center’s Cognitive Comedy class, where caregivers and people living with dementia learn improv basics.   Dr. Anne Basting on why asking questions and staying present matters in tough caregiving moments.   Improv teacher and elder care educator Karen Stobbe shares her personal story of using improv to care for her mother with Alzheimer’s.   Researchers Dr. Candace Kemp, Dr. Jennifer Craft Morgan, and Amanda Lee Williams discuss the science behind improv’s benefits for caregivers.   Leah Lawler, creator of Cognitive Comedy, explains why teaching improv to older adults is her passion.   Whether you’re a caregiver, a healthcare professional, or simply curious about creative approaches to aging, this episode offers practical insights and inspiring stories that will change the way you think about care.  Resources available on the episode webpage linked below   Check out the Penn Memory Center’s Cognitive Comedy class  Learn more about improv (UChicago News)  Explore Timeslips’ website   Learn more about Anne Basting   Check out Karen Stobbe’s “In the Moment”  Listen to Karen and Mondy’s story in This American Life   Read Dr. Kemp and Dr. Morgan’s study on improv and dementia care (The Gerontologist)  Watch more of Leah Lawler talking about Cognitive Comedy  A list of improv games/exercises (improvencylcopedia.org)    Special thanks this episode to Jean Haskell and her Cognitive Comedy participants, Barry and Ray, as well as Anne Basting, PhD, Karen Stobbe, Candace Kemp, PhD, Jennifer Craft Morgan, PhD, and Amanda Lee Williams.  T Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.    The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsors, the TIAA Institute and Rothkoff Law Group. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging.    C...
Can AI Provide Artificial Care?
2025/11/25
Artificial intelligence is everywhere in 2025, and elder care is no exception. As the older adult population continues to grow, AI has the potential to provide desperately needed support. Both at home and in the hospital, AI systems are being developed that can summarize data, predict patient outcomes, and offer preventative interventions. These systems could help clinicians be more efficient as well as shoulder some of caregivers’ many responsibilities. Yet for as many problems as AI seems to solve in healthcare, many more questions arise as to how these innovative tools can be implemented ethically.  On this episode of the Age of Aging, we take a deep dive into the developing role of AI in the care of older adults.   We first hear from expert researchers in this space about the potential ways AI could be used to assist in the lives of older adults. Then, the co-founder of New Days AI, Dr. Babak Parviz, discusses how his company utilizes AI to help older adults protect against dementia. Finally, we look into the potential challenges and ethical questions that come with implementing AI in dementia care.   Resources available on the episode webpage linked below   NASA’s definition of artificial intelligence  Learn more about Dr. Alex Mihailidis  More on Dr. George Demiris  More information on Penn AI Tech   Visit New Days AI’s website  Learn more about Dr. Mai Lee Chang  More information on Oonjee Oh  “AI Photos” (Saturday Night Live)    Special thanks this episode to Alex Mihailidis PhD, PEng, George Demiris PhD, FACMI, Babak Parviz, PhD, Mai Lee Chang, PhD, and Oonjee Oh, MSN, RN    The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.    The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsors, the TIAA Institute and Rothkoff Law Group. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging.    Caring for an aging loved one isn’t easy — but you don’t have to do it alone. At Rothkoff Law Group, we guide families across New Jersey and Pennsylvania through every stage of your aging journey. Our team of elder care attorneys, geriatric care coordinators, and public benefits specialists advocate for your loved one’s well-being and your peace of mind. Rothkoff Law Group — your partner in advocacy and senior care planning, every step of the way. Visit RothkoffLaw.com.     
Democratizing Dementia
2025/11/11
Innovation in dementia care is revolutionizing the way we diagnose and treat older adults with neurodegenerative diseases. New tests have allowed doctors to diagnose patients with diseases like Alzheimer’s more accurately than ever before. The anti-amyloid therapies Lecanemab and Donanemab provide a real treatment for those living with Alzheimer’s. While these innovations are incredible for those experiencing dementia, they are also beginning to change our culture around dementia generally.  On this episode of the Age of Aging, Terrence Casey sits down with Dr. Jason Karlawish to talk about major steps forward in dementia care and how they’re changing the way we speak about dementia.   The topics in this conversation are pulled directly from the Dr. Karlawish’s new column, Neurotransmissions, in STAT News. Dr. Karlawish discusses the stigma-based way we talk about dementia in popular culture and the damage it does to older adults. He explains how new diagnostic tests and treatments are reshaping this culture by providing patients and caregivers with greater knowledge of their condition as well as hope for improvement. Dr. Karlawish said these changes will ultimately reduce the stigma associated with dementia and allow for further progress in the care of older adults.   Resources available on the episode webpage linked below   Read Dr. Karlawish’s column, Neurotransmissions, on STAT News  Read Illness as a Metaphor and AIDS and Its Metaphors by Susan Sontag  Learn more about LATE   Read Joshua Grill’s piece in the Philadelphia Inquirer    Special thanks to Dr. Jason Karlawish, MD, for being a part of this episode.   The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.    The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsors, the TIAA Institute and Rothkoff Law Group. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging.    Caring for an aging loved one isn’t easy — but you don’t have to do it alone. At Rothkoff Law Group, we guide families across New Jersey and Pennsylvania through every stage of your aging journey. Our team of elder care attorneys, geriatric ca...
Making Art, Creating Mind
2025/10/28
Although the Age of Aging often focuses on science, art has been a recurring theme. In Season 2, Episode 2, “Diet, Exercise, and... Doodling?”, we explored how creativity can support longevity. However, beyond art’s apparent health benefits, making and consuming art can also help us better understand the experience of aging. In many ways, the change and loss associated with aging are best understood through art.  Today’s episode of the Age of Aging looks once again at art creation in aging through the stories and work of three artists living with brain disease.   Joe Vanek, a stage designer for more than 40 years, experienced a stroke that changed how he viewed time and creativity.  Scott LaMascus left graduate school in poetry to care for his father with ALS, finding meaning through writing and reflection.  Neesa Becker-Procaccino, a professional illustrator, stopped working after an Alzheimer’s diagnosis but returned to art as a way to heal and connect.  Each artist faced disruption. Yet through art, each found a way to continue creating and redefining identity in the face of illness.   Resources available on the episode webpage linked below  Watch the full video featuring Neesa Becker-Procaccino   Learn more about Joe Vanek  Read more of Joe Vanek’s story  Read “Dispatches from the Dark Side of the Moon” and “Hesitant Light”  Check out more of Joe Vanek’s illustrations  Saint Patrick  The Queen of Hearts  Our Lady Guadalupe   The Child of Prague  Nutcracker  The Snow Queen  Follow Joe Vanek on Instagram  Learn more about Scott LaMascus ...
What is it Like to be Dan?
2025/10/14
Over the past year, the Age of Aging has spoken with expert clinicians who study the brain, as well as individuals living with neurodegenerative diseases like Alzheimer’s. We believe that these two perspectives are essential for fully understanding dementia in 2025.  In today’s episode, we hear from someone who can speak to both perspectives.  Dr. Daniel Gibbs is a retired neurologist and author currently living with Alzheimer’s disease. Joined by his wife and caregiver, Lois Seed, he sat down with Age of Aging Executive Producer Dr. Jason Karlawish to discuss Dan’s experience. While the two physicians have had repeated conversations over the years concerning Dan’s diagnosis, Lois’ presence highlights how the disease has progressed and how their relationship has taken on new caregiving dynamics.  What you will hear is an authentic depiction of living with Alzheimer’s disease, along with insights on how a partner begins to care for that person’s changing mind.  Resources available on the episode webpage linked below  Read A Tattoo on My Brain: A Neurologists Personal Battle with Alzheimer’s Disease. Watch the documentary, A Tattoo on My Brain  Learn more about Dan and Lois’ story  (American Heart Association)  Read Dr. Daniel Gibbs’ blog   Special thanks to Daniel Gibbs, MD, PhD, and Lois Seed for being a part of this episode.   The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharpe.  The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsor, the TIAA Institute. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging. 
Canine Care
2025/09/30
At the Penn Memory Center, we often recommend exercise, social engagement, and a solid support system to help people age well. Owning a dog is not on that list, but maybe it should be. For many older adults, dogs are more than companions. They’re motivators to stay active, reasons to connect with neighbors, and steady sources of comfort through life’s challenges. Emerging research suggests that that this age-old bond between humans and dogs may be one of our healthiest friendships. On this episode of The Age of Aging, we celebrate dogs, and how they might help us live long, healthy lives.   First, we hear from caregivers and dog owners about how their dogs help them care for their loved ones with dementia. Then, Professor Philip Tedeschi explains how humans’ co-evolution with dogs has made us perfect support system for one another. Lynn Cronomiz recounts how a powerful moment between a therapy dog and her mother with Alzheimer’s helped her process her mother’s passing. Finally, we explore humans’ inseparable connection with nature through the biophilia hypothesis.  Resources available on the episode webpage linked below Dog ownership in the U.S. statistics – American Veterinary Medical Association  “2025 Alzheimer’s Facts and Figures” –  Alzheimer’s Association  Listen to Season 1 Episode 4, “Diagnosing Dementia,” featuring Lynn Cronomiz  Learn more about the Insitute for Human-Animal Connection  Visit KPETS, which Lynn Cronomiz does her therapy dog work with  Learn more about the “biophilia hypothesis”  Petfinder to adopt a pet near you  Visit the American Kennel Club website for more information on dog breeds    Special thanks to Tom Casey, Miguel Centeno, Kathy Oldfield, Philip Tedeschi LCSW, MSSW, Lynn Cronomiz, and Carlo Siracusa DVM, PhD, DACVB, DECAWBM    The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.    The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsor, the TIAA Institute. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insig...
Just Aging
2025/09/16
When we think about justice, older adults aren’t always top of mind. Yet in the United States, seniors often face stigma, exploitation, and insufficient social support, all while navigating cognitive and physical decline. As lifespans continue to grow globally, aging is a future we all hope to reach. So how do we ensure that future is just? And what does justice for older adults truly look like?    Welcome to Season 4 of The Age of Aging! We’re kicking off with a vital and multifaceted topic: elder justice. Joining us are three leading voices who help unpack the legal, cultural, and systemic challenges facing older adults — and what can be done to address them.  MT Connolly, author and elder justice advocate, explores the deep-rooted cultural and structural issues that shape aging in America, and offers ideas for meaningful reform.  Charlie Sabatino, former director of the American Bar Association’s Commission on Law and Aging, explains how working with an elder law attorney can help preserve autonomy and dignity throughout the aging process.  Judge Lois Murphy shares insights from the courtroom, including a real-life guardianship case that illustrates the complexities and consequences of our legal system’s approach to elder care.  If you enjoy the episode, please leave us a review and share it with a friend. Got a story idea for Season 4 or beyond? Reach out to us at [email protected].    Resources  Listen to Season 1 Episode 2, “Living Well with Purpose,” about supported decision-making.  Read The Measure of Our Age: Navigating Care, Safety, Money, and Meaning Later in Life by MT Connolly.  Learn more about MT Connolly.  More information on the RISE model  CDC Mortality Trend Graph  2023 CDC Life Expectancy  Learn more about Charlie Sabatino  More information on guardianship in Pennsylvania   Learn more about Judge Murphy     Special thanks to Charlie Sabatino JD, MT Connolly JD, and Judge Lois Murphy.  The Age of Aging is a Penn Memory Center production hoste...
This Moment in Alzheimer's: Taking Stock and Look Forward
2025/08/26
Welcome to a mid-year bonus episode of The Age of Aging! While the podcast takes a short break between seasons, we wanted to bring you a special update on the state of Alzheimer’s today. Penn Memory Center Co-Directors Dr. Jason Karlawish and Dr. David Wolk sat down with Terrence Casey to share their reflections from this year’s Alzheimer’s Association International Conference (AAIC), which they attended earlier this summer. They discuss their biggest takeaways, including the impact of NIH funding cuts, the rapid innovations that continue to shape the field, and what they’re keeping their eye on for next year’s conference in London.   We hope you enjoy and stay tuned for season 4 of The Age of Aging this fall! If you enjoy the show, leave us a review and share this episode with a friend. If you have any story suggestions for Season 4 and beyond, contact us at [email protected].   Resources  Learn more about the Alzheimer’s Association and AAIC  Special thanks to Jason Karlawish, MD and David Wolk, MD.  The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp. 
Season 3 Finale: Neither Superheroes, Nor Angels
2025/07/22
When we talk about dementia on this podcast, we are often talking about its most common cause: Alzheimer's disease. However, dementia has many causes, and among the most prevalent after Alzheimer’s is Lewy Body Disease. Though it can share similarities with Alzheimer’s, Lewy Body Dementia (LBD) has distinct symptoms and challenges that can complicate diagnosis, treatment, and caregiving.   On the season 3 finale of the Age of Aging, we explore Lewy Body Disease and its impact on caregivers and families.   We begin with a clip from the documentary Facing the Wind, which follows two caregivers as they navigate caring for their husbands with Lewy Body Disease. Then, Co-Host Terrence Casey shares his reflections on a live Q&A following a screening of the film in Philadelphia. Finally, Dr. Jason Karlawish provides a deeper insight into Lewy Body Disease, its significance in the world of aging research, and what it reveals about caregiving today.  Resources  Find an upcoming screening of Facing the Wind  Learn more about Lewy Body Dementia  National Institute of Health booklet on Lewy Body Dementia  More resources on Lewy Body Dementia Association website  Special thanks to Tony Heriza, Deirdra Fishel, and Linda Szypula for sharing their film with us and being a part of this episode. Special thanks as well to ARTZ Philidelphia for presenting the screening and Q&A. The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp. 
Okay, Let's Talk About Sex and Dementia
2025/07/08
Sex and intimacy can be difficult topics to navigate, especially for caregivers and their partners facing the challenges of a dementia diagnosis. These conversations are often avoided, yet the emotional toll of intimacy-related struggles can be profound, bringing feelings of grief, confusion, and isolation. The stigma surrounding sex and dementia only deepens this silence, making open dialogue all the more essential.   On this episode of The Age of Aging, we explore one caregiver’s deeply personal journey through love, loss, and change. Alison Lynn, Director of Social Work at the Penn Memory Center, speaks with author and advocate Lisa Marshall about her book Oh, Hello Alzheimer’s: A Caregiver’s Journey of Love.   Lisa shares the story of her husband Peter’s Alzheimer’s diagnosis and the emotional complexities that followed — including her decision to end their sexual relationship. With honesty and vulnerability, she reflects on the grief, guilt, and growth that came with that choice, offering insight and solidarity to others navigating similar paths.  Resources  This week’s Beautiful Question: What is a place with special meaning to you? Leave us a message at (571) 449-6474.  Read Lisa Marshall’s book, Oh, Hello Alzheimer's: A Caregiver's Journey of Love  Visit Lisa’s website   Special thanks to Lisa Marshall and Alison Lynn, MSW, LCSW for being a part of this episode.    The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.   
Transforming a System of Care
2025/06/24
The U.S. healthcare system is changing—especially when it comes to caring for older adults. The COVID-19 pandemic revealed how vulnerable our aging population is, and how unprepared many parts of the system remain. Overstressed nursing homes, overworked primary care physicians, and a lack of accessible resources for dementia care remain persistent challenges.   But there’s hope. New technologies, treatments, and care models are reshaping what aging and diagnosis can look like. The question now is: How do we deliver these advances to the people that need them most?   In this episode of the Age of Aging, we explore the evolving landscape of elder care in the U.S.  We start with Dr. PJ Brennan, the Chief Medical Officer of Penn Medicine who discusses the challenges the U.S. healthcare system is currently facing with its elder population. Then Dr. Kyra O’brien explains why the new anti-amyloid therapies, lecanemab and donanemab, might help more people get diagnosed and allow clinics like the Penn Memory Center to expand their resources. Finally, Dr. O’Brien dives into the new federal program “GUIDE,” which aims to reshape dementia care across the country.    Resources  This week’s Beautiful Question: What is something that you could teach someone? Leave us a message at (571) 449-6474.  Listen to our episode on anti-amyloid therapies, “In Sickness and in Health”  Read more about anti-amyloid therapies  More information about GUIDE at Penn Medicine  Penn GUIDE interest form  General information on GUIDE (cms.gov)  Special thanks to PJ Brennan, MD, and Kyra O’Brien, MD, for being a part of this episode.   The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.   
Early Onset Caregiving
2025/06/10
We often think of dementia as something that affects the oldest among us, and that’s often true; at the Penn Memory Center, the average age of diagnosis is between 70 and 75. In most of those cases, caregiving falls to a spouse, partner, or adult child. But what happens when dementia is diagnosed before the age of 65?  In this episode of the Age of Aging, we explore early onset dementia and the young caregivers who step up when their lives are just beginning. The stories of teens and young adults reveal the unique challenges of caregiving and what they can teach us about care across all ages.  We begin with a segment from a recent episode of Science Friday, where Executive Producer Dr. Jason Karlawish discussed the FDA’s recent approval of new diagnostic blood tests for Alzheimer’s disease. Then, Paige Censale shares the life-changing decision she faced: accept a full scholarship to college or stay home as the sole caregiver for her mother. We then learn about Lorenzo’s House, an organization dedicated to supporting young caregivers and families impacted by early onset dementia. Finally, we hear from Sierra, a 16-year-old from South Pasadena California who began caring for her father with early onset dementia when she was just 8 years old.    Resources  This week’s Beautiful Question: What is something in your home that you treasure? Leave us a message at (571) 449-6474.  Thank you to Science Friday for letting us play part of their episode with Dr. Karlawish. You can listen to the full episode here.   Check out Paige Censale’s website  Learn more about early onset dementia (WebMD)  Learn more about Lorenzo’s House  Join Lorenzo’s House’s “Youth Summit” (June 20 – 21)   Special thanks to the Science Friday team, Jason Karlawish, MD, Paige Censale, Diana Cose M. ED, Patti LaFleur M. ED, CPD, Sierra Mercer, and Alison Lynn, MSW, LCSW, for being a part of this episode.   The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp. 

Podcast reviews

Read Age of Aging podcast reviews


5 out of 5
19 reviews
★★★★★
SSzamK 2026/01/16
Rx for Alzheimer’s
Dr. Karlawish and Dr. Wolk provided a great overview of the current state of Alzheimer’s treatments and the exciting developments in the pipeline. It...
★★★★★
janmcj 2025/12/18
Interesting and varied
Some awesome hosts! Love all their insights on the variety of topics :)
★★★★★
Running Drained 2025/12/10
Better Than I Expected
Age of Aging replaces fear with insight and practical advice. Smart, engaging hosts and genuinely inspiring guests.
★★★★★
kathygirl52000 2025/11/12
Science brings hope!
For the first time in my career in senior living I see hope for patients carrying a dementia diagnosis and for upcoming generations!
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