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Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health

Advertise on podcast: Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health

Rating
★★★★★
5
from
16 reviews
This podcast has
35 episodes
Language
English
Explicit
No
Date created
2025/02/20
Latest episode
2026/02/02
Average duration
48 min.
Release period
15 days

Description

The Histamine Well is a podcast for health practitioners and patients alike, bridging the gap between complex science and practical understanding. With a focus on histamine, methylation, and related health topics, the show translates advanced concepts into actionable insights for practitioners while empowering patients with accessible, evidence-based knowledge.Your host, Joanne Kennedy, is a naturopath and expert in histamine intolerance, MTHFR, and methylation. She is also an author and runs an online group coaching program for practitioners and students on histamine and methylation. Jo loves breaking down complex science into clear, easy-to-understand language, offering practical tips and the latest insights to empower you to take charge of your health.

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Check latest episodes from Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health podcast


34. Vitamin B12 Explained: Forms, Methylation, Homocysteine & Absorption
2026/02/02
In this episode of The Histamine Well Podcast, Joanne is joined by scientist James Bradshaw for an in-depth discussion on Vitamin B12 and its critical role in human health. Together, they unpack the complex biochemistry of Vitamin B12, exploring how it supports methylation pathways, homocysteine metabolism, and neurological function. This episode provides clarity on why Vitamin B12 deficiency is often overlooked, how genetic variations can impact B12 utilization, and why choosing the correct form of B12 supplementation is essential for optimal outcomes. Joanne and James also examine the different forms of Vitamin B12—including methylcobalamin, hydroxocobalamin, adenosylcobalamin, and cyanocobalamin—discussing how each functions in the body and when one may be more appropriate than another.  The conversation highlights common signs and symptoms of B12 deficiency, from fatigue and brain fog to neurological and mood-related concerns, and offers practical, evidence-informed strategies for assessing and supporting B12 status. This episode is especially valuable for health practitioners, functional medicine clinicians, and individuals seeking a deeper understanding of how Vitamin B12, genetics, and methylation intersect to influence long-term health. In This Episode, You’ll Learn: Why Vitamin B12 is essential for methylation, detoxification, and neurological healthThe different forms of Vitamin B12 and how they work in the bodyCommon and often-missed symptoms of Vitamin B12 deficiencyHow B12 supports homocysteine regulation and cardiovascular healthHow to choose the right B12 supplementation based on individual needsThe connection between genetics, methylation pathways, and B12 metabolism ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
33. Over-Methylation Explained: COMT, Estrogen, Mood & Inflammation
2026/01/26
In this episode of the Histamine Well Podcast, Joanne Kennedy explains why over-methylation is becoming increasingly common, especially among women, and how it’s closely linked to COMT enzyme activity, estrogen dominance, mood disorders, and inflammation. This episode breaks down the biochemistry of methylation in a clear, practical way—exploring how estrogen affects COMT, why some people react badly to methylated B vitamins, and how over-methylation can drive symptoms such as anxiety, irritability, insomnia, nervous system overload, and chronic inflammation. Joanne also introduces the Mood Sense test as a real-time tool for assessing methylation status, helping practitioners and individuals move away from guesswork and toward personalized, symptom-aware support. With insights inspired by James Bradshaw, this episode is essential listening for anyone navigating estrogen-related symptoms, mood instability, or complex supplement reactions. What you’ll learn in this episode: Why over-methylation is becoming more common, especially in womenHow COMT enzyme activity influences mood, stress tolerance, and neurotransmitterThe connection between estrogen dominance and over-methylationCommon emotional and inflammatory symptoms linked to over-methylationWhy methylated supplements can worsen symptoms for some peopleHow the Mood Sense test can help assess methylation status in real timeKey considerations for supporting estrogen balance and calming the nervous system✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
32. Hormone Replacement Therapy in Perimenopause: Interview with Rachel Schaefer
2026/01/12
Are your hormones out of balance? In this episode of The Histamine Well Podcast, Joanne sits down with Rachel Schaefer, founder of Ginkgo Integrative Medicine, to demystify perimenopause and the role of Hormone Replacement Therapy (HRT) in supporting women’s health. They explore what actually happens during hormone fluctuations in perimenopause, how to recognize estrogen dominance, and the benefits and risks of estrogen, progesterone, and testosterone therapy. Rachel shares practical insights on how personalized care, detailed hormone testing, and integrative medicine can help women navigate this transitional stage with confidence. You’ll learn how early intervention with the right HRT protocol can improve energy, mood, sleep, and long-term wellbeing—plus how to avoid common pitfalls with synthetic hormones, patches, and oral estrogen. Whether you’re just entering perimenopause or already considering HRT, this episode offers a clear, empowering look at how to restore hormonal harmony and thrive through midlife. Learn more about Rachel’s integrative approach to hormone health and women’s wellbeing: Website: https://www.ginkgointegrativemedicine.com/ Instagram: @ginkgointegrative🧪 Rachel’s Recommended Annual Serum Lab Panel (Age 40+) Done fasting, ideally once per year. Tracks hormonal shifts & key biomarkers: CBC w/ diff · Ferritin, TIBC, Iron sat · CMP · GGT · SHBG · DHEA-S · Free & Total Testosterone · Estradiol LC/MS (Cycle Day 2–3) · FSH (Day 2–3) · LH · Progesterone LC/MS (Day 20–21) · Homocysteine · MMA · HSCRP · Insulin · HbA1c · ApoB · Lp(a) · TSH · Free T4 · Free T3 · rT3 · TPO antibodies · ANA · Vitamin D Additional testing based on the case: DUTCH · Tiny Health GI Pro · Mira · 3x4 Genetics · Total Tox Burden · DEXA · OATS · Mood Sense 💡 At-Home Hormone Tracking — Listener Discount Rachel checked in with Mira, a home-based hormone urine testing device, to offer a special 20% off discount for listeners of The Histamine Well Podcast. 🔸 Public Discount Code: 2GINGKO20 🔸 Mira Website: www.miracare.com ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
31. How to Protect Your Home from Mold and EMF Exposure with Building Biologist Jo Lia
2025/11/10
Is your home secretly affecting your health? In this episode of The Histamine Well Podcast, Joanne’s colleague Melanie Peers sits down with Building Biologist Jo Lia to uncover the hidden dangers of mold, electromagnetic fields (EMF), and poor indoor air quality. Jo shares her journey into building biology and explains how unseen environmental factors—like hidden mold spores or constant EMF exposure—can impact your immune system, mood, and energy levels. Together, they break down what you can do to make your home a truly healthy space, from proper mold testing and remediation to simple steps that minimize EMF radiation in your daily life. If you’ve struggled with chronic inflammation, fatigue, allergies, or unexplained symptoms, this episode will help you connect the dots between your home environment and your health. What You’ll Learn: How to identify the early signs of mold in your homeThe truth about EMFs and how they affect your healthSimple ways to reduce EMF exposure from Wi-Fi and devicesWhat to do if you suspect mold contamination — and how to remediate safelyWhy modern airtight homes can worsen indoor air qualityHow to improve ventilation and maintain clean indoor airHow to find and work with a certified Building BiologistPractical tips for creating a toxin-free, health-supportive living environment Connect with Jo Lia: 🌿 Website: https://www.notoxrox.com/ 📸 Instagram: @notoxrox 📘 Facebook: facebook.com/notoxrox Australian Society of Building Biologists: https://www.asbb.org.au/ ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
30. Hydrogen Sulfide SIBO Explained: Symptoms, Testing & Treatments with Rosaria Nithart
2025/10/27
In this episode of The Histamine Well Podcast,  Joanne sits down with Rosaria Nithart, a French-based naturopath specializing in digestive health, to uncover the complexities of Hydrogen Sulfide SIBO—one of the most misunderstood forms of Small Intestinal Bacterial Overgrowth (SIBO). Together, they break down how Hydrogen Sulfide SIBO differs from hydrogen- and methane-dominant SIBO, exploring the unique bacteria and biochemical pathways involved. Rosaria shares her step-by-step naturopathic framework for identifying, testing, and treating Hydrogen Sulfide SIBO naturally. The conversation also dives deep into the role of sulfur metabolism, oxalates, and molybdenum in managing symptoms and restoring gut balance. Listeners will learn: The root causes and drivers behind Hydrogen Sulfide SIBOHow to identify key symptoms and understand testing limitationsThe connection between sulfur, oxalates, and bacterial imbalancesPractical treatment strategies that support gut healing without extreme dietsHow Hydrogen Sulfide SIBO links to UTIs, histamine intolerance, and detox pathwaysWhether you’re a practitioner seeking deeper clinical insights or a patient navigating chronic gut issues, this episode offers a clear, actionable approach to understanding and managing Hydrogen Sulfide SIBO naturally.  Connect with Rosaria Nithart: Website: rosarianithart.com | rosarianithart.itFacebook: facebook.com/rosaria.nithartInstagram: @rosarianithartnaturopatheBreath Tests for Hydrogen, Methane & Hydrogen Sulfide: Trio Smart (USA / Canada)– Trio-Smart® — The only 3-Gas SIBO Breath Test: https://www.triosmartbreath.com/Nordic Labs (Europe) – https://nordiclabs.com/EProduct.aspxInvivo Healthcare (UK): https://invivohealthcare.com/Teletest (Spain): https://www.teletest.es/ | https://www.facebook.com/teletest/✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
29. Healing Chronic Illness Through Nervous System Regulation with Jacqui Raadschelders
2025/10/13
In this episode of The Histamine Well Podcast, Joanne Kennedy sits down with physiotherapist and neuro-rehabilitation specialist Jacqui Raadschelders to explore the link between nervous system dysregulation and chronic illness. You’ll learn how the limbic system, vagus nerve, neuroplasticity, and brain retraining techniques play a vital role in recovery from conditions influenced by trauma, mold exposure, and stress. Jacqui shares her journey from traditional physiotherapy to a holistic, trauma-informed approach—highlighting the impact of emotions, beliefs, and environment on healing. Key topics include: Fight, flight, and freeze responsesThe role of the limbic system in chronic illnessPractical vagus nerve toning exercisesEmotional regulation and belief system shiftsBrain retraining for long-term resilienceTailored strategies to regulate and recalibrate the nervous systemWhether you’re a practitioner, student, or someone navigating chronic illness, this conversation offers practical tools and evidence-based insights for restoring balance and supporting your nervous system health. Enrol in the Regulate Your Nervous System online program and receive 10% off with the code JOANNE10. This program is for anyone navigating chronic illness, burnout, stress or persistent symptoms who’s ready to understand their body in a new way. Enrol here  ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
28. Oxalates, Adrenal Fatigue & Blood Sugar Imbalance: Tracy’s Journey to Healing
2025/09/29
In this episode of The Histamine Well Podcast, Joanne is joined by colleague Melanie and patient Tracy, who shares her powerful story of navigating the challenges of oxalates, histamine intolerance, adrenal fatigue, and blood sugar imbalances. Tracy’s journey highlights the complex relationship between oxalates, adrenal and blood sugar imbalances, and oxalate dumping symptoms. With support from Melanie, she has worked through paradoxical reactions to magnesium and B6, learned strategies for managing sulfur metabolism, and discovered the importance of patience and persistence in recovery. Melanie provides expert insights into identifying oxalate issues, tailoring dietary strategies, and supporting detoxification pathways. Together, the conversation emphasizes the importance of professional guidance, careful supplementation, and tracking progress when addressing oxalates. Whether you’re a practitioner seeking functional medicine insights or someone personally struggling with oxalates, histamine intolerance, or methylation challenges, this episode offers practical advice and encouragement to support your healing journey. What You’ll Learn in This Episode How oxalates affect adrenal health and blood sugar balanceWhat to know about oxalate dumping symptoms and how to manage themThe role of sulfur metabolism and detox pathways in oxalate sensitivityWhy do some people experience paradoxical reactions to magnesium and B6Dietary and lifestyle strategies for long-term oxalate managementThe link between oxalates, histamine levels, and methylationWhy professional support is crucial for navigating complex health issues Why This Episode Matters Oxalates are often overlooked in discussions about chronic health, but they can play a major role in gut health, nutrient absorption, adrenal function, and histamine intolerance. Tracy’s story shows how challenging—but also how rewarding—it can be to address these issues with the right support and strategies. If you’ve been struggling with fatigue, blood sugar swings, or unexplained reactions to supplements, this conversation offers valuable guidance. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
27. Why Blood Tests & Functional Medicine Tests Aren’t the Full Story: Gut, Histamines, Genes, Hormones & More!
2025/09/15
In this episode of The Histamine Well Podcast, host Joanne Kennedy and guest Mariella Gebhardt unpack the nuances of medical testing in functional medicine—and why lab results alone don’t always tell the full story. From histamine intolerance and methylation issues to gut health, Candida, mold exposure, and hormone imbalances, Joanne and Mariela explore the limitations and benefits of testing while emphasizing the importance of case history, symptoms, and environmental factors in shaping treatment. They break down popular tests—including organic acids tests (OAT), microbiome testing, genetic testing, thyroid panels, iron tests, and hormone testing—highlighting when they’re useful, what they may miss, and how to interpret them in real-world practice. Whether you’re curious about functional medicine, women’s hormones, SIBO, oxalates, DAO enzyme activity, or vitamin B12 deficiency, this episode offers clarity on when testing helps—and when it can be misleading. What You’ll Learn in This Episode: Why clinical context matters more than test results aloneHow to approach Candida, mold, and mycotoxin testingThe role of the DAO enzyme in histamine breakdownPitfalls of genetic and gene testing for methylationHow to interpret iron tests, thyroid panels, and hormone markersInsights on organic acids, oxalates, and gut health testingIf you’ve ever wondered whether your test results reflect the whole picture—or how to navigate functional medicine testing with confidence—this conversation will help you understand the bigger picture. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
26. Mold & Chronic Illness: Symptoms, Testing, and Detox Strategies with Melanie Peers
2025/09/01
Could mold be the missing link in your chronic health puzzle? In this episode of The Histamine Well Podcast, Joanne speaks with Melanie Peers about the hidden impact of mold illness and how it can silently drive histamine intolerance, food sensitivities, and long-term inflammation. You’ll discover how mold exposure can: Raise histamine levels and trigger mast cell activationDisrupt methylation and detoxification pathwaysCause oxalate buildup and sulfur imbalancesLead to neurological, digestive, respiratory, and skin symptomsMelanie shares how to spot the difference between everyday mold allergies and systemic mold-related illness, how to test for mold in your home and body, and what a mold detox protocol can look like in real life. Whether you’re a health practitioner or someone struggling with unexplained symptoms, this episode gives you practical strategies for identifying mold, removing exposure, and supporting recovery. What You’ll Learn in This Episode Key symptoms of mold illness you might be missingHow mold drives histamine intolerance and CIRS (Chronic Inflammatory Response Syndrome)The mold–oxalate connection and why it matters for gut healthEffective mold testing for your home and bodyMold detox strategies and the role of sulfur in recoveryEnvironmental tips for reducing mold exposureReal-life case studies of mold-related illness and recovery ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
25. Energy Healing Essentials for Perimenopause: A Discussion with Claire Tait
2025/08/18
Perimenopause isn’t just a physical transition — it’s an emotional, spiritual, and energetic shift. In this empowering episode of The Histamine Well Podcast, Joanne speaks with Claire Tait, a holistic kinesiologist and intuitive energy healer, about how to navigate perimenopause with greater balance, calm, and self-awareness. Claire shares her expertise on how kinesiology, reiki, acupressure, yoga, and other holistic practices can support women during this powerful life stage. You’ll learn how to regulate your nervous system, address anxiety naturally, and embrace the spiritual metamorphosis of perimenopause. This conversation is filled with practical rituals, personal insights, and empowering perspectives to help you surrender to the changes, reconnect with yourself, and thrive during midlife. What You’ll Learn in This Episode: Emotional & spiritual transitions of perimenopauseHow self-awareness supports hormonal and emotional healthKinesiology: blending Eastern and Western healing methodsReiki, acupressure, and yoga for grounding and calmNatural approaches to easing anxiety during perimenopauseThe role of the nervous system in healingHow intermittent fasting impacts women’s healthEmbracing aging and rejecting societal pressuresThe energetics of female empowerment✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
24. Histamine & Anxiety – How High Histamine Triggers Fight-or-Flight Symptoms
2025/08/11
Can histamine be the hidden reason behind your anxiety? In this episode, I break down how histamine acts as a neurotransmitter in the brain — and why an overload can leave you wired, anxious, and unable to relax. We dive into how methylation, estrogen, mold, and gut inflammation (including SIBO and oxalates) all feed into the histamine-anxiety loop. Whether you're a practitioner treating patients with anxiety or someone who’s tried everything to feel better — this episode gives you a deeper lens into the hidden biochemical drivers of mental health symptoms. If you've ever felt overstimulated, panicked, or like anxiety hits out of nowhere, you're going to want to hear this one. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
23. Could Your Histamine Intolerance Actually Be Sulfur Intolerance?
2025/08/04
We break down how disrupted sulfur metabolism can mimic histamine symptoms—severe bloating, crushing fatigue, joint pain, brain fog, skin flushing—and why reactions to garlic, onions, eggs, brassicas, NAC, and glutathione are key clues. You’ll learn the roles of sulfite/sulfide vs. sulfate, SUOX + molybdenum, B12, mitochondria, hydrogen sulfide overgrowth, and environmental drivers like mold and oxalates. We also cover testing pointers (homocysteine, stool, OAT), why low-sulfur diets are only a short-term tool, and practical next steps for practitioners and patients. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
22. PMDD, Histamine Intolerance & Methylation: Anastasia’s Journey from Breakdown to Breakthrough
2025/07/28
In this deeply personal and powerful episode, Joanne sits down with patient Anastasia Lamont to explore her journey through PMDD (Premenstrual Dysphoric Disorder), histamine intolerance, and overmethylation. Anastasia opens up about the debilitating symptoms she endured — from suicidal ideation and extreme fatigue to chronic pain and severe skin conditions — and how her life transformed through targeted naturopathic treatment. Together, they unpack the emotional and clinical journey, revealing the role of diet, supplements, and real-time methylation testing in stabilizing mood and reclaiming wellness. This is a must-listen for anyone living with PMDD or supporting someone who is — and for practitioners looking to understand the powerful intersection between mood, hormones, and histamine. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
21. How to Treat SIBO Naturally: Diet, Herbs, Testing & the Clinical Approach That Works
2025/07/21
Struggling with persistent SIBO symptoms or unsure where to start with natural treatment? In this episode, I break down exactly how I treat SIBO in clinic — from diet and herbs to overlooked factors like biofilm, enzymes, histamine, and oxalates. Whether you're a health practitioner, student, or someone personally dealing with SIBO, you'll walk away with a deep understanding of the step-by-step process required for real, lasting results — not just temporary relief. What I Cover: ✔️ Why a low FODMAP diet is non-negotiable if you're treating SIBO naturally ✔️ How to use testing — and retesting — to guide effective treatment ✔️ The best herbs for hydrogen and methane SIBO (and why they differ) ✔️ The role of SIFO (Small Intestinal Fungal Overgrowth) and how to spot it ✔️ Why addressing biofilm is essential for treatment success ✔️ How digestive enzymes (including brush border support) accelerate healing ✔️ The hidden role of histamine intolerance in stubborn cases ✔️ Why oxalates can spike on a low FODMAP diet — and what to do about it ✔️ What to do when the migrating motor complex (MMC) isn’t working ✔️ The best prokinetics, binders, and enzyme supplements I use in practice ✔️ When and how to safely reintroduce foods after treatment ✔️ What recurring SIBO is trying to tell you ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!
20. Acid Load, Mineral Depletion & the Hidden Link to Histamine Intolerance & Oxalates
2025/07/14
In this episode of The Histamine Well, we're diving into one of the most overlooked root causes behind symptoms like fatigue, histamine intolerance, hormonal imbalance, oxalate sensitivity, mood swings, and chronic inflammation: acid load and mineral depletion. You'll learn: Where acidity in the body comes from — from diet and inflammation to mitochondrial dysfunction and gut dysbiosisHow acid load disrupts key systems, including hormones, energy, detoxification, and neurotransmittersWhy histamine and oxalates are inherently acidic — and how that ramps up symptoms in sensitive individualsThe role of bicarbonate and minerals in buffering acid and maintaining systemic pH balanceHow to interpret functional blood markers like bicarbonate and the anion gap (and what they actually mean)Why simply adding more supplements won’t fix a stressed nervous system or mineral-depleted biochemistryWhich alkalizing mineral formulas and mitochondrial supports Joanne recommends in clinical practice — including Basica, Orthoplex Alkamin, and ATP FuelWhether you're a practitioner, student, or someone deep in their own healing journey, this episode will shift how you view symptoms and recovery — especially if you’ve hit a wall despite ‘doing all the right things. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. 🎤 Have a topic suggestion? Submit it here!

Podcast reviews

Read Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health podcast reviews


5 out of 5
16 reviews
★★★★★
Chelseamcleod 2025/03/27
Best in class
This information is simply leading to the industry. Highly recommend for patients and practitioners alike 🩷
★★★★★
LaurenReeseYoga 2025/03/08
Thank you for this podcast
As a perimenopausal woman who has been dealing with so many histamine issues I’m incredibly grateful for this podcast and can’t wait for more episodes...
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