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Stephanie Gambetta starts this episode with a solo update on what’s happening with Loop Health, her current peptide routine, the upcoming Loop Beauty line, and some of the changes she’s making in her own health at 51. She talks about building muscle in midlife, improving her sleep during menopause, prioritizing recovery, monitoring her blood work, and the mitochondrial stack she’s currently using. She also gets personal about the realities of building Loop Health, navigating life without Instagram, experimenting with TikTok, and making more time for friendships, travel, and the things that actually fill her back up.  Then Stephanie sits down with Aabid Farukhi, a board-certified musculoskeletal radiologist, to break down DEXA scans and why the number on your bathroom scale doesn’t tell the whole story. They explain how a DEXA scan measures muscle mass, body fat, visceral fat, bone density, and even muscle symmetry between different sides of your body. Stephanie also walks through her own DEXA results, including gaining a pound of muscle while microdosing a GLP-1, and shares why she uses these scans to see whether her training, nutrition, peptides, and lifestyle are actually changing her body composition.  Stephanie and Aabid also dig into one of the biggest concerns surrounding GLP-1s: losing muscle and bone mass while losing weight. They discuss resistance training, protein, visceral fat, bone health during perimenopause and menopause, and why tracking body composition can give you a much clearer picture of your progress than obsessing over weight alone. Whether you’re using GLP-1s and peptides or simply trying to build muscle, lose fat, and stay strong as you age, this episode is about understanding what’s actually happening inside your body.  This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing medications, peptides, supplements, hormones, or other treatments. Peptides & Compounds Discussed SS-31MOTS-c5-Amino-1MQNAD+Thymosin Alpha-1KPVGLP-1 receptor agonistsGlutathioneGHK-CuProgesteroneMagnesiumCreatine LOOPHEALTH20 to get 20% off a dexascan with Dexafit OC (https://www.oc.dexafit.com/)

Psychologist Dr. Sarah Sarkis returns to The Loop Podcast to talk about the psychology of midlife and why the changes that happen in your 40s and 50s can feel so uncomfortable. Stephanie and Sarah break down the idea of a “midlife crisis” and look at what’s actually happening when your identity, relationships, career, family life, hormones, and priorities all begin shifting at the same time. Sarah explains why discomfort doesn’t necessarily mean something is wrong, how the things that worked earlier in life may need to be upgraded, and why the whispers telling you something needs to change can eventually become impossible to ignore.  Stephanie also shares what this has looked like in her own life, from divorce and rebuilding her identity to the recent challenges with Instagram, postponing her Loop event, and unexpectedly finding a new creative outlet on TikTok. They talk about what happens when your growth makes the people around you uncomfortable, why progress includes plateaus and even periods of regression, dealing with comparison and rejection, grieving an old version of your life, and learning to keep moving when you have no idea exactly where you're headed. Sarah also shares a different way to think about whether a major life change is “working”: sometimes constantly measuring your progress is perfectionism disguised as excellence. Stephanie and Sarah also preview the upcoming Aspen retreat, where Sarah will help women explore the stories they’re carrying into midlife, decide which ones still serve them, and become more intentional about what they want the next chapter of their lives to look like. Join Steph & Dr. Sarkis at the Loop retreat ( http://www.theloopway.com/events/aspen ), $500 off exclusively for podcast listeners available here:  https://buy.stripe.com/8x27sKfz30JKb1S7jo3gk01

Karen Martel, CEO of Midlife Solutions, joins Stephanie Gambetta for a candid conversation about perimenopause, menopause, hormone replacement therapy, peptides, GLP-1s, and what actually changes in a woman’s body during midlife. Karen shares how her own experience being pushed into early menopause at 42 changed the direction of her career, despite already working as a nutritionist and doing everything she thought was “right.” She and Stephanie break down the early signs of perimenopause, progesterone and estrogen loss, stubborn midlife weight gain, brain fog, mood changes, and why you can’t always diet, exercise, or biohack your way out of hormonal changes. Stephanie also opens up about her own HRT journey at 51, including progesterone, estrogen, testosterone pellets, and the changes she’s currently navigating. Together, she and Karen discuss why HRT and peptides can work together rather than compete, combining GLP-1s with optimized hormones, microdosing, food noise, preserving muscle, thyroid health, and why some women plateau on GLP-1s even at higher doses. They also get into starting HRT later in life, overdoing biohacking, wearable data, DEXA scans, peptide safety, and why women need individualized protocols instead of copying whatever someone else is taking online. Karen and Stephanie also challenge the idea that suffering through menopause deserves a badge of honor. The goal isn’t perfection or doing every wellness trend imaginable. It’s understanding your body, finding the right tools, and building a sustainable approach that helps you feel strong, confident, and healthy through the second half of life. Use code LOOP10 for 10% off at Midlife Solutions. Shop Midlife Solutions This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing hormones, medications, peptides, supplements, or other treatments. Peptides, Hormones & Compounds Discussed Hormone Replacement Therapy (HRT)EstrogenProgesteroneTestosteroneGLP-1 receptor agonistsRetatrutideGHK-CuTB-500BPC-157MOTS-cTesamorelinThyroid medication

Sienna Olson, founder of SLO Rx, joins The Loop Podcast for a conversation about what happens when you’re doing everything “right” but your body still isn’t responding. Sienna holds a Doctorate in Chiropractic and a Master’s in Sports Medicine, and her own journey from ski racing and bodybuilding to gaining 50 pounds in five months changed the way she thinks about metabolism, body composition, and women’s health. Today, she works with women who are juggling careers, families, and packed schedules but still wondering why their energy is low and their hard work isn’t showing up in the mirror. Her philosophy is simple: more isn’t better, right is. Stephanie and Sienna break down GLP-1s, peptides, protein, resistance training, body composition, and why simply increasing a dose or adding another wellness tool isn’t always the answer. They discuss tirzepatide versus retatrutide, microdosing, BPC-157, why Sienna takes a conservative approach to peptides, and how the scale can completely distort your perception of progress when you’re building muscle. They also get into comparison, consistency, sleep, finding a sustainable routine, and giving women permission to want to feel healthy, strong, confident, and hot without apologizing for it. It’s a conversation about getting away from quick fixes and finding the tools that actually fit your body and your life.  Peptides & Compounds Discussed TirzepatideRetatrutideGLP-1 receptor agonistsBPC-157SelankSemaxMicrodosing GLP-1s / peptide protocols This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing medications, peptides, supplements, training, or other treatments.

Plastic surgeon Dr. Jonathan Zelken returns to The Loop Podcast for a candid conversation about plastic surgery, peptides, aging, and the treatments that are actually worth your time and money. Stephanie opens up publicly about getting a deep plane facelift at 48, why she chose to do it before she felt like she “needed” one, and what the recovery was really like. Together, Stephanie and Dr. Zelken break down deep plane versus SMAS facelifts, fat transfer versus filler, Botox, buccal fat removal, rhinoplasty, breast augmentation, skin resurfacing, body contouring after weight loss, and why subtle results often require more work than social media makes it seem. Then they flip the script and put Stephanie in the expert seat for a rapid-fire round on peptides, GLP-1s, HRT, muscle building, sleep, libido, recovery, and injectable versus oral peptide therapy. Stephanie also challenges Dr. Zelken to try a new peptide and body-composition protocol before returning to the podcast later this year. It’s an honest, funny conversation about looking better, feeling better, and making informed choices without pretending there’s one right way to age. This episode is for educational purposes only and should not be considered medical advice. Always consult qualified medical professionals before undergoing surgery or beginning or changing medications, peptides, hormones, supplements, or other treatments. Peptides & Compounds DiscussedBPC-157TB-500CJC-1295IpamorelinGHK-CuGLP-1 receptor agonistsRetatrutideTesamorelinPT-141Thymosin Alpha-1EpitalonDSIPHGH / growth hormoneHormone Replacement Therapy (HRT)

Peptide expert and manufacturer Trevor Kruder returns to The Loop Podcast for an inside look at what’s happening behind the scenes in the rapidly changing world of peptides. Trevor joins Stephanie Gambetta to break down the recent FDA hearings, what they actually mean for compounded peptides, why manufacturing quality and sterility matter, and how to tell the difference between legitimate products and questionable sources. They also explore some of the most exciting developments Trevor is working on, including Klotho research, longer-lasting peptides, oral peptide technology, new applications for women’s health, regenerative medicine, and even peptide therapies for pets. Trevor also shares an incredible personal update involving fertility after believing for decades that he couldn’t have children, while Stephanie opens up about her own experiences with peptide reactions, GLP-1 microdosing, muscle gain, and finding the right tools for her body. This episode is a deep dive into where peptide science is headed and why education, testing, quality, and responsible use matter more than ever. This episode is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional before starting or changing medications, peptides, supplements, or other treatments. Peptides & Compounds Discussed KlothoBPC-157TB-500CJC-1295IpamorelinTesamorelinGHK-CuGLP-1 receptor agonistsPT-1415-Amino-1MQP21NAD+GlutathioneMK-677, which Trevor specifically notes is not a peptideGrowth hormone / growth-hormone-related therapies

Lauren Pronger, founder of SuperWell and Well Inspired Travels, joins Stephanie Gambetta for an honest conversation about burnout, midlife wellness, peptides, and learning how to take care of yourself without turning health into another full-time job. Lauren shares how a period of intense family health challenges, including her husband Chris Pronger’s career-ending concussion, pushed her own body into severe burnout and eventually inspired the SuperWell philosophy. Together, Lauren and Stephanie discuss the eight pillars of SuperWell living, why sleep can be an early warning sign for burnout, creating space and boundaries, balancing wellness with actually enjoying your life, using health data without obsessing over it, building muscle through protein and progressive overload, and why peptides and HRT should support a strong lifestyle foundation rather than replace it. They also dive into peptide cycling, gut health, GLP-1 microdosing, wellness travel, and the idea that becoming “super well” isn’t about perfection. It’s about consistently finding the tools that help you feel your best. This episode is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional before starting or changing medications, peptides, hormone therapy, supplements, or other treatments. Peptides & Compounds Discussed GHK-CuThymosin Alpha-1KPVMOTS-cSS-31NAD+GLP-1 MicrodosingSelank

Trainer Brad Davidson returns to The Loop Podcast to break down why lasting body composition change comes from strategy, patience, and recovery, not punishing workouts or quick fixes. Stephanie shares how Brad helped her rebuild strength after her injury and completely change the way she thinks about exercise, food, and her body. Together, they explain German Body Composition training, progressive overload, why lifting weights can outperform excessive cardio, how rest periods and training cycles affect results, and why fitness needs to change as we get older. They also discuss peptides as recovery tools, nutrition, DEXA scans, building muscle while microdosing a GLP-1, and the new Loop Health workout program designed to take the guesswork out of strength training. If you're tired of working harder without seeing results, this episode is about learning how to train smarter and build a body that supports your life. This episode is for educational purposes only and should not be considered medical or fitness advice. Consult qualified healthcare and fitness professionals before making changes to your training, medications, peptides, or wellness routine. Peptides Discussed CJC-1295TesamorelinBPC-157TB-500GHK-Cu / “Glow”GLP-1 receptor agonists including Stephanie's discussion of microdosing Join Loop Health to start Steph & Brad’s workout: https://loop.health/movement And interested in getting a Dexascan?  Use code LOOPHEALTH20 at www.dexafit.com for 20% off. Join Stephanie & Loop IRL, check out our upcoming events here: “https://www.theloopway.com/events”

Entrepreneur, investor, and podcast host Chris Harder joins Stephanie Gambetta to share one of the most personal stories he's ever told publicly. After suffering a stroke in his sleep at just 46 years old, Chris opens up about losing part of his vision, battling brain fog, depression, and anxiety, and the tools that helped him reclaim his health and confidence. Together, Chris and Stephanie discuss how peptides became part of his recovery journey, the importance of therapy, why compliance and proper dosing matter, and how lifestyle choices can dramatically impact long-term health. They also explore GLP-1 microdosing, food noise, strength training, entrepreneurship, burnout, collaboration, and why asking for help is one of the strongest things you can do. Whether you're curious about peptides, navigating your own health journey, or simply looking for inspiration after a setback, this conversation is packed with honest insights and practical takeaways. In this episode you'll learn: • Chris Harder's stroke recovery story  • How peptides supported his brain health journey  • The importance of therapy and mental health after trauma  • Why "more isn't always better" with supplements and hormones  • GLP-1 microdosing beyond weight loss  • The psychology of food noise and metabolic health  • How high performers can avoid burnout  • Why collaboration is the ultimate business advantage This episode is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional before beginning or changing any medication, peptide, supplement, or treatment plan. Peptides Discussed SemaxSelankNAD+BPC-157TB-500GLP-1 receptor agonists (microdosing)Testosterone replacement therapy (TRT) (discussed alongside peptide protocols) Join Stephanie & Loop IRL, check out our upcoming events here: “https://www.theloopway.com/events”

Sara Banta joins Stephanie Gambetta for an eye-opening conversation about peptides, GLP-1 medications, liver health, thyroid function, and why the foundation of your health matters before adding any new treatment or supplement. Sara shares the personal health journey that inspired her supplement company, the challenges her family faced, and what she learned while helping her children overcome serious health issues. Together, they discuss why some people experience histamine reactions to peptides, the role of liver function in getting results, how to simplify your supplement routine, and why nutrition, blood work, and metabolic health should come before chasing the next wellness trend. If you've ever wondered why peptides or GLP-1s aren't giving you the results you expected, this episode offers a thoughtful perspective on building a healthier body from the inside out. This episode is for educational purposes only and should not be considered medical advice. Always consult your healthcare provider before starting or changing any medication, peptide, supplement, or treatment plan. Peptides Discussed GLP-1 receptor agonistsTirzepatideBPC-157GHK-CuKPVThymosin Alpha-1Peptide bioregulators (general discussion) Shop the peptides & supplements Stephanie trusts, with 15% off your first purchase: https://startwithloop.com/?ref=STEPHANIEGAMBETTA Book a coaching call with Stephanie: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-?month=2025-11 https://acceleratedhealthproducts.com/LOOP 10% coupon code = LOOP10 Join Stephanie & Loop IRL, check out our upcoming events here: “https://www.theloopway.com/events”

Returning guest Renetta Ascher Caya joins Stephanie Gambetta for a fun, honest conversation about peptides, GLP-1 microdosing, hormones, strength training, and the wellness habits that actually make a difference in midlife. Renetta shares how she travels with peptides, the dosing mistake that led to an unforgettable holiday disaster, and the treatments she consistently keeps in her routine. Together, they challenge common GLP-1 myths, explain why muscle loss is often connected to nutrition and lifestyle rather than the medication alone, compare oral peptides with injections, and build peptide stacks for fat loss, recovery, longevity, sleep, and brain health. They also discuss blood work, testosterone pellets, cold plunges, creatine, protein, peptide quality, and the importance of finding an approach that works for your individual body. Plus, Stephanie introduces the new Loop Health app and the support it will provide for peptide protocols, reconstitution, dosing reminders, nutrition, workouts, and community. This conversation shares personal experiences and is intended for educational purposes. Individual health needs vary, so work with a qualified healthcare professional before beginning or changing any treatment. Peptides Discussed GLP-1 receptor agonistsTirzepatideRetatrutide, referred to as “Retta”BPC-157KPVThymosin Alpha-1SemaxEpitalonIpamorelinTB-500GHK-CuSS-31MOTS-cNAD+••Glutathione Join the Loop Health Community: https://loop.health Shop the peptides & supplements Stephanie trusts, with 15% off your first purchase: https://startwithloop.com/?ref=STEPHANIEGAMBETTA  Book a coaching call with Stephanie: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-?month=2025-11

Entrepreneur and Kroma Wellness founder Lisa Odenweller joins Stephanie Gambetta for one of the most honest conversations yet about health, hormones, entrepreneurship, and learning to advocate for yourself. Lisa shares the incredible story behind building Beaming into one of the country's most successful healthy café brands before walking away to rebuild her life and launch Kroma Wellness. She also opens up about the years-long health mystery that left her exhausted, inflamed, and unable to tolerate hormone therapy or peptides until she finally uncovered the root cause. Together, Stephanie and Lisa discuss parasites, gut health, AI as a health research tool, blood work, GLP-1s, peptides, muscle building, nutrition, and why making yourself a priority isn't selfish, it's essential. Whether you're navigating perimenopause, optimizing your wellness routine, or simply looking for practical ways to take better care of yourself, this episode is full of actionable insights and practical takeaways to help you become the CEO of your own health. Use code STEPHANIE15 for 15% off at Kroma Wellness: kromawellness.com Peptides Discussed • BPC-157 • MOTS-c • AOD-9604 • GLP-1 medications • DHK-Cu (Copper Peptide) • Collagen peptides • Creatine (discussed alongside peptide protocols) • Hormone Replacement Therapy (HRT)

What happens when you stop surviving and start rebuilding your life? In Episode 61 of The Loop Podcast, Steph sits down with Lauren Orshansky, host of The X-Wives Lounge Pod, for an honest conversation about divorce, motherhood, entrepreneurship, health, and the courage to start over. Lauren shares how becoming a single mom inspired her to create a platform where women feel seen, heard, and supported through life's biggest transitions. Together, Steph and Lauren discuss the emotional work required to leave unhealthy relationships, overcoming fear, raising confident daughters, building authentic friendships, and navigating the pressures of social media. They also dive into how chronic stress impacted Lauren's health, the importance of advocating for yourself, lifestyle changes that supported her recovery, and how peptides fit into a personalized wellness journey. Whether you're navigating divorce, personal growth, entrepreneurship, or simply looking for inspiration to become your healthiest self, this conversation is filled with practical wisdom and hope. In this episode you'll learn: • Why fear often stands between you and freedom  • How to rebuild your identity after divorce  • Why authenticity attracts the right people into your life  • The impact chronic stress has on your health  • Lifestyle changes that supported Lauren's healing journey  • How peptides fit into a personalized wellness plan  • Why staying curious is one of the most powerful life skills Special Offers: ✅ Get Loop Supplements:  TheLoopWay.com ✅ Join the Loop Beauty Beta:  Loop-Beauty.com ✅ Save 10% at Loop BioLabs:  Use code PODCAST at LoopBioLabs.com

Are your peptides or GLP-1 medications really the problem, or is there something else happening beneath the surface? In Episode 60 of The Loop Podcast, Steph is joined by peptide specialist Polo for an in-depth conversation about blood work, nutrient deficiencies, GLP-1 optimization, and why personalized health matters more than following trends. Together they break down why some people stall on GLP-1s, the importance of mitochondrial health, how proper nutrition affects peptide therapies, and why blood testing can reveal issues you would never find with a standard lab panel. They also discuss emerging peptide therapies, ATX403, supplements that support longevity, peptide stacking, sexual health peptides, skincare, and how the new Loop Health community is helping people make informed decisions about their health. Whether you're already using peptides, considering GLP-1 therapy, or simply looking to better understand your body, this episode is packed with practical education to help you optimize your health safely. In this episode you'll learn: Why blood work is essential before changing your protocolThe biggest mistakes people make while using GLP-1 medicationsHow nutrient deficiencies can impact peptide effectivenessWhy personalized coaching leads to better health outcomesEmerging peptides and supplements worth watchingHow Loop Health is changing the way people learn about peptide therapies⚠️ Medical Disclaimer: This podcast is for educational purposes only and should not be considered medical advice. Always consult your healthcare provider before beginning any medication, peptide therapy, supplement, or treatment. Peptides Discussed GLP-1 medicationsRetatrutideATX403MOTS-cSLU-PP-332 (SLU-PP-321 discussion)BPC-157TesamorelinSS-31PT-141 (Bremelanotide)GHK-CuCJC-1295BPC-157CJC/Ipamorelin (Growth Hormone Secretagogues)CmaxSelankThymosin Alpha-1Also discussed: NAC (N-Acetyl Cysteine)GlycineMethylated B VitaminsBerberineUrolithin AGlutathione support

Hey Loop Community! Instead of a new episode of The Loop Podcast, I'm sharing the first episode of my brand-new podcast, I'm Obsessed, with Lori Harder. We started this show because we found ourselves constantly talking about the things we're obsessed with, from peptides and wellness to personal growth, business, relationships, and everything in between. In this quick introduction, I share why Lori and I partnered up, what inspired the name, and why I'm excited to bring these conversations to both of our communities. I hope you enjoy getting to know Lori, learning a little more about me, and checking out the first episode of I'm Obsessed. Next week we'll be back with another episode of The Loop Podcast. Listen here: https://podcasts.apple.com/us/podcast/peptides-glp-1s-womens-health-why-your-best-years-arent/id1087926635?i=1000773080006