
Advertise on podcast: Peptide of The Week
Rating
4.6from
This podcast has
135 episodes
Language
EnglishPublisher
JD Denham and Will HaasExplicit
No
Date created
2025/05/31
Latest episode
2026/10/01
Average duration
68 min.
Release period
4 days
Description
Hosted by JD Denham and Will Haas, The Peptide of The Week Podcastis your no-BS guide to peptides, performance, and total body optimization. Whether you’re an athlete, a high performer, or just hungry to feel better, move better, and live stronger this show’s for you. JD and Will dive deep into real-world protocols, hard-earned lessons, and the science behind what actually works. With expert guests and raw conversations, you’ll get everything from cutting-edge peptide talk to diet, training, recovery, and mindset. No fluff. No filters. Just the tools to rebuild your body and upgrade your life.
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Check latest episodes from Peptide of The Week podcast
Telehealth vs Research Peptides: The Truth Nobody Tells You | Peptide of the Week Q&A #61
2026/10/01
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Warrior Coaching: https://www.warrior-makerscoaching.com
Peptide Of The Week Website: https://peptideoftheweekpod.com
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
JD Denham and William T. Haas are back fresh from the Olympia where they connected with some of the biggest names in the peptide space. This week they settle the telehealth vs research peptide debate once and for all, break down how to mix multiple compounds into one syringe the right way, introduce FLGR 242 as the most exciting new muscle building peptide on the market, cover ALS protocols, foot injury dosing for a teenage athlete, osteoporosis in a 60 year old with celiac, and what to stack when you cannot gain muscle despite doing everything right.
🔬 Topics Covered
• Is your telehealth rep actually lying to you about research peptides?
• The one thing that exposes a fake or underdosed peptide company immediately
• Why mixing the wrong peptides in one syringe could ruin your whole stack
• The new muscle building peptide that is showing 23% growth in early data
• Down 125 pounds and training for HYROX at 49: what his stack actually looks like
• Why this 59 year old functional medicine doctor still cannot gain muscle
• Peptides for a 15 year old athlete with sesamoiditis: what is safe and what is not
• Can Wolverine actually target multiple pain areas at the same time?
• ALS at 72: the best theoretical peptide protocol when nothing is guaranteed
• Osteoporosis with celiac disease: why injectables change everything
Chapters:
00:00 – Cold Open
00:21 – Intro
00:31 – Welcome Back & Olympia Recap
03:40 – School & Coaching Program Updates
06:15 – New Website & YouTube Ban Update
07:58 – JD's Mold-Related Cough Update
08:52 – Q&A: Telehealth vs. Research Peptides
18:15 – Q&A: Combining Multiple Peptides in One Syringe
25:05 – Q&A: TRT Protocol for a 21-Day Costa Rica Hike
31:30 – Q&A: Reconstituting ARA-290 Properly
34:31 – Q&A: Best Peptides for a BJJ Practitioner's Recovery
40:24 – Q&A: Somatropin & Peptide Stack at Goal Weight
45:30 – Q&A: BPC/TB500/KPV for a Teen's Foot Injury
50:01 – Q&A: Peptides to Slow ALS Progression
51:28 – Q&A: Wolverine Stack for Multiple Pain Points
56:38 – Q&A: Osteoporosis, Celiac Disease & Outro
Peptide of the Week: Epithalon & Glutathione – Longevity, Sleep & Detox
2026/09/28
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas get back to basics with two compounds that belong in almost everyone's stack. Epithalon for longevity, sleep, and cellular aging. Glutathione for detox, liver protection, and immune support. Simple, powerful, and underutilized.
Chapters:
00:00 – Intro
00:09 – Show Updates & Shirt Talk
02:15 – Heading to the Olympia
02:58 – Behind the Scenes of Bodybuilding Prep
05:26 – JD's Mold-Related Cough Diagnosis
07:50 – New Podcast Format & Upcoming Compounds
10:01 – School & Coaching Program Updates
10:41 – Carnivore vs. Macros: Finding What Works
13:33 – Epitalon: Origins in Russian Bioregulator Science
15:03 – Why Most Peptides Lack FDA Clinical Trials
17:20 – Big Pharma's Incentives & Hidden Cures
21:53 – Epitalon: Longevity, Immune Support & Sleep
27:53 – What to Stack With & Avoid on Epitalon
32:13 – Glutathione: Why Everyone Should Take It
34:57 – Delivery Methods & Global Uses
39:49 – Dosing Protocols: Epitalon & Glutathione Math
We cover:
🧬 What is Epithalon?
– A four amino acid synthetic peptide made of alanine, glutamate, aspartate, and glycine
– One of Dr. Khavinson's Soviet bioregulators developed in the 1970s military research program
– Works directly on the pineal gland, the pea-sized gland in your brain that regulates sleep and hormones
– In 2026, an FDA advisory committee voted 7 to 4 to recommend adding it to the approved compound list (advisory only, not yet policy)
– Cannot be patented because it is a naturally occurring compound, so there is no financial incentive for big pharma to fund large trials
🔬 What Epithalon does
– Telomere lengthening: Dr. Khavinson's studies showed it extends the telomere caps on your chromosomes, theoretically slowing cellular aging. Animal models showed extended lifespan
– Sleep and circadian rhythm reset: deepens sleep, reduces nighttime waking, helps reset disrupted sleep cycles. One of the top reasons people run it
– Immune resilience: lowers free radical damage systemically, especially helpful for overtrained athletes and chronically stressed people
⚠️ What to avoid with Epithalon
– Alcohol
– High-dose melatonin (it can replace melatonin, do not stack them)
– Extra sedatives while running it for sleep
– Theoretical caution with active cancer due to pineal gland's role in cell regulation (not proven, just noted)
– Not WADA banned but classified as a non-approved substance for tested athletes
🛡️ What is Glutathione?
– Discovered in 1888, actively used in Italy to treat Parkinson's after independent human trials
– Your body's master antioxidant and the most important detox compound available
– Scavenges free radicals, recycles vitamins C and E so they keep working, and escorts toxins out of the body
🔬 What Glutathione actually does
– Liver detox and protection: number one clinical use in Western medicine, especially post-alcohol and for fatty liver support
– Parkinson's and neuroprotection: proven in human trials to protect nerves from chemotherapy damage
– Immune support and long COVID recovery: being used in post-viral fatigue and long COVID protocols
– Skin lightening: the number one global use. High doses will make you pale. Low doses for wellness will not
Follow us on social media:
JD's Socials: https://hoo.be/jddenhamofficial
Will's Socials: https://hoo.be/williamthaas
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Peptide Q&A #60 – Live from South Carolina, COA Verification, HGH Long Game & SIBO
2026/09/24
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas are live from South Carolina touring a 503A/503B FDA-approved compounding facility. They cover how to vet a peptide source beyond the COA, HGH as a long-term play, seborrheic dermatitis triggered by HGH, SIBO and Candida gut protocols, peptides for eye health, and longevity tools for women over 60.
Chapters:
00:00 – Intro
00:10 – Welcome Back & South Carolina Trip
00:27 – Visiting a 503A/503B Lab
02:01 – Why They Take These Trips & Dealing With Online Hate
05:28 – Skool Platform & Coaching Program Updates
09:42 – New Format: Feedback From Listeners
10:34 – Recap: The Elkins Cattle Co Episode
14:08 – Q&A: Tracking a COA to a Specific Bottle
19:40 – Q&A: HGH vs. TESA/IPA Secretagogues
25:36 – Q&A: Statin/Blood Pressure Meds & SS-31 for Eye Health
29:02 – Q&A: HGH Causing Seborrheic Dermatitis
33:59 – Q&A: Fixing SIBO & Candida
39:06 – Q&A: How Much Visceral Fat Is Normal?
44:05 – Q&A: Reducing Inflammation & Blood Pressure Naturally
48:47 – Q&A: BAM-15 & SLU-PP-332 Coupling Explained
1:01:12 – Q&A: CJC/Ipa Reactions & the Ideal Longevity Stack
We cover:
• Can You Trust a COA Is From the Right Batch?: Why there's no perfect answer, why cost and transparency are the best vetting tools, and why good companies test the same batch multiple times
• HGH vs Tesamorelin —The Long Game: Why Tesamorelin still retains its visceral fat-burning properties even alongside HGH, why secretagogues are redundant on HGH, and why five-plus years is the real timeline
• HGH Causing Seborrheic Dermatitis: Why elevated IGF-1 increases sebaceous gland activity, why switching to a secretagog may reduce but not eliminate the issue, and when dropping HGH altogether is the right call
• SIBO and Candida Protocol: Why oral BPC and KPV are the foundation, the role of fasting and carnivore in starving off gut overgrowth, and why Dr. Scott and holistic practitioners are the right people to guide this
• Peptides for Eye Health After Statin Damage: Why SS-31 is the most promising compound with clinical trials behind it, and why BPC, TB-500, Epithalon, and Visalutin are also worth researching
• 8% Body Fat Firefighter Overtraining: Why one or two rest days accelerate results, why sleep and stress management outrank adding compounds, and why fasting is JD's top lean-out tool for men
• Longevity Stack for Women Over 60: Why HGH is the unanimous pick for bone density and belly fat, why SS-31 before MOTS-C is non-negotiable, and why creatine is the most underrated supplement for older women
• Klotho Peptide — Early Impressions: Why JD and Will are both running it now and will report back once they have firsthand experience to share
You're a warrior. Act like one.
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Peptide Of The Week Website: https://peptideoftheweekpod.com
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Warrior Coaching: https://www.warrior-makerscoaching.com
Peptide of the Week: What's Really in Your Beef With Tim Elkins
2026/09/21
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Tim Elkins, JD's first mentor in business and now owner of Elkins Cattle Co., one of Texas's largest cattle operations spanning 40 to 50 thousand acres. This one is not about peptides. It is about what is actually in your food and why it matters just as much.
Chapters:
00:00 – Intro
00:13 – Meeting Tim Elkins
01:36 – Tim's Background: Finance to Cattle Ranching
07:53 – The Time Management Lesson That Changed JD's Career
10:35 – Cattle Ranch to Table: How the Industry Really Works
12:23 – The "Big Four" Monopoly Explained
14:24 – Why Elkins Cattle Co Refuses to Cut Corners
18:46 – The Truth About Foreign Beef
21:00 – Why Ribeye Prices Doubled & Who Profits
25:03 – Grocery Store Ground Beef: What's Really In It
29:44 – What's Legal But Should Shock You
34:29 – How to Tell a Cheated Steak From a Real One
39:10 – The Truth About "Wagyu" Labels at Costco
42:47 – Grass-Fed vs. Grain-Finished Explained
47:26 – Inside a Feedlot: How They Track Every Animal
54:08 – How Buying Local Can Starve Out the Big Four & Outro
We cover:
🐄 How beef actually gets to your table
– 90% of American beef passes through just four companies: JBS, Cargill, Tyson, and National Beef
– These four have a stranglehold monopoly on the entire industry and prioritize speed and profit over quality
– 70% of beef consumed in America is foreign beef. Most people have no idea
– Animals are often slaughtered at under 12 months old or as old non-producing cows to cut costs
– Horse meat in fast food chains: confirmed. And it is more widespread than just Taco Bell
🚫 What store-bought beef actually contains
– Hormones, antibiotics, mRNA vaccines, and artificial additives are standard practice in commercial beef production
– Wagyu labeling loophole: a product only needs 0.001% wagyu genetics to legally use the wagyu label. That ribeye at Costco is not what you think it is
– "Grass-fed" on a label means almost nothing. Every cow has eaten at least one piece of grass. The label has no meaningful standard
– Pink slime in ground beef is real and it comes from reputable-looking places, not just fast food
– Veal in most restaurants is almost certainly a calf that died in transit or in a pen, not one that was intentionally raised for that purpose
🥩 What Elkins Cattle Co. does differently
– Zero hormones, zero antibiotics, zero mRNA vaccines, zero shortcuts
– All animals are 30 months old at slaughter, not 12 months
– 40 to 50 thousand acres across Texas, nearly 9,000 head of cattle
– Consumer direct: order by Monday, ships frozen to your door by Tuesday
– Retina scanning technology tags every animal daily, tracking food intake, water, health markers, and time spent laying down. Red X spray marks any animal that needs attention that morning
– Grass-fed AND grass-finished: fed four specific grasses including coastal Bermuda, Klein, native grasses, and winter oats to mimic the intramuscular fat quality of grain-finished beef without any GMO grain inputs
– Animal welfare is non-negotiable: a stressed, unhappy cow does not gain weight properly and the difference shows up in the meat
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Follow Tim Elkins:
Website: https://www.elkinscattleco.com
X (Twitter): https://www.x.com/elkinscattleco
Instagram: https://www.instagram.com/elkinscattleco/
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Coaching Website: https://www.warrior-makerscoaching.com/
Peptide Q&A #59 – Warrior-Makers Wellness Center, HGH for Women & FOX-O4 vs Fasting
2026/09/17
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham is joined by peptide consultant Michael Vandal and Nora Addam, wholesale director at Forge Biolabs, while Will enjoys Hawaii. They cover the new Warrior Maker Wellness Center, overtraining at 8% body fat, FOXO4-DRI vs fasting for autophagy, circadian rhythm eating for women, HGH for post-menopausal belly fat, and R maintenance dosing.
Chapters:
00:00 – Intro & Meet the Co-Hosts
02:28 – School Platform Update & Losing Social Media
03:53 – Coaching Program Details
04:43 – Warrior Maker Wellness Center Announcement
09:55 – Q&A: Overtraining as a Firefighter at 8% Body Fat
17:48 – Q&A: Ammonia Smell During HIIT on "R"
22:35 – Q&A: Stubborn Belly Fat After Major Weight Loss
29:42 – Q&A: High Inflammation Markers & Mitochondrial Peptides
39:44 – Q&A: FOXO4-DRI, Epitalon & the Case for Fasting
50:39 – Q&A: Getting Your Doctor to Optimize Your Hormones
55:10 – Q&A: Urolithin A vs. SS-31 & MOTS-C
59:33 – Q&A: Should You Stack "R" & Tirzepatide?
1:03:34 – Q&A: Fatigue on "R" (Age 46)
1:09:14 – Q&A: Longevity Peptides for Postmenopausal Women
1:10:05 – Q&A: "R" Dosing Math & Maintenance vs. Cycling Off
1:16:32 – Outro & Coaching Program Plug
We cover:
• Warrior Maker Wellness Center is Coming: Hyperbaric chambers, red light, and longevity services dropping in downtown Huntington Beach and Warrior Makers supplements by Christmas
• 8% Body Fat Firefighter Overtraining: Why a rest day is when you actually build muscle, why sleep and stress management matter more than adding compounds, and why fasting is JD's top add for lean men
• MOTS-C Personal Experience When It Works and When It Doesn't: Why some people feel nothing on MOTS-C and why blood work and stool testing reveal more than any peptide response
• FOXO4-DRI vs Fasting for Autophagy: Why JD prefers fasting over FOXO4 for senescent cell clearance, why a 72-hour fast quarterly may be the most powerful longevity tool available, and why Epithalon pairs perfectly with a four-week break
• Fasting for Women Is Different: Nora's case for eating to your circadian rhythm, why skipping breakfast triggers thyroid issues in perimenopausal women, and why front-loading protein and calories changes everything
• 47-Year-Old Female First Cycle Break Protocol: Why Epithalon for 10-20 days plus high-dose SS-31 is the ideal four-week reset, and why staying on glutathione through the break makes sense
• Fatigue on R in Women: Why under-fueling is almost always the culprit, why MOTS-C was a game changer for Mike on R, and why glycine and magnesium glycinate are non-negotiable for sleep
• Longevity Stack for Post-Menopausal Women at 55: Why HGH is the unanimous answer, why blood work including A1C and fasting insulin must come first, and why it targets belly fat specifically
• R Maintenance vs Cycling Off at Goal Weight: Why 1 meg every five days is Mike's sweet spot, why JD believes building discipline off the compound matters just as much, and why both approaches are valid
You're a warrior. Act like one.
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Peptide Of The Week Website: https://peptideoftheweekpod.com
Coaching Website: https://www.warrior-makerscoaching.com/
Peptide of the Week: Gut Health Deep Dive With Liz Roman, The Poop Queen
2026/09/14
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Liz Roman, owner of FitMom Functional Health, certified functional practitioner, co-host of The Health Revival Show, and the self-proclaimed (and trademarked) Poop Queen. If your gut is jacked, this episode is for you.
Chapters:
00:00 – Intro & Meeting Liz "The Poop Queen"
01:51 – Why Everyone's Gut Is Struggling Today
07:09 – The Foundation: Diet, Hormones & Stress Come First
08:59 – JD's Gut Story & Where to Start Healing
13:13 – Stomach Acid: The Missing Domino
15:39 – Order of Operations: Parasites, Detox & Ivermectin
19:40 – Rapid Fire: What Should Poop Look Like?
21:28 – Prebiotics vs. Probiotics vs. Postbiotics Explained
26:39 – Junk Products & Peptide Scams to Avoid
30:59 – Daily Habits: Eating & Bathroom Hygiene
35:27 – Fasting & Protein Timing for Women
40:11 – Decoding Chronic Bloating
43:10 – Liz's Personal Health Journey
46:57 – SIBO, Candida & the Real Role of Antibiotics
52:07 – Liz's Favorite Peptides & Daily Supplement Stack
We cover:
🦠 Why everyone's gut is a mess
– Chronic stress, poor diet, COVID spike proteins, nutritional deficiencies, and environmental toxins are all converging at once
– Spike proteins attach to mast cell receptors throughout the gut microbiome and cardiovascular system, shifting how the immune system behaves
– Magnesium, B vitamins, and vitamin D deficiencies accelerated post-2020 and are still largely unaddressed
– You will never out-supplement, out-peptide, or out-hormone a bad diet and poor stress management. Period.
🧬 The north-to-south digestion process
– Stomach acid is the first domino. When it is low (from stress, aging, NSAIDs, medications, or past substance use), nothing downstream works properly
– Stomach acid must be robust enough to emulsify protein into amino acids AND kill incoming parasites, pathogens, viruses, and bacteria
– Always take betaine HCL in capsule form, never powder, the capsule protects it from being neutralized before it reaches the stomach
– Low stomach acid fails to signal the pancreas, which then fails to release digestive enzymes, which then fails to signal the liver and gallbladder to release bile
🫐 Bile is the missing link nobody talks about
– Bile is your internal built-in antimicrobial, circulating through the small intestine 15 to 17 times per meal
– It is your body's natural defense against SIBO. When bile flow is compromised, bacteria overgrow where they should not be
– The liver-gut axis is real, anatomically proven, and almost entirely ignored by conventional medicine
– Supporting bile flow with things like TUDCA is essential, especially on GLP-1s and high-fat diets
🦠 SIBO, Candida, parasites, and the carnivore trap
– Restrictive diets like carnivore can clear symptoms short term but also deprive gut bacteria of the fibers, polyphenols, and prebiotics they need to thrive
– Parasite cleanses need to be a minimum of 45 to 60 days, not 7-day moon cycles. The parasite lifecycle is 45 to 60 days from egg to adult
– Antibiotics take 6 months to 2 years to recover from after just one round. If you must take them, support the gut simultaneously
📺 Subscribe for more no-fluff peptide education every week.
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Follow Liz Roman:
Website: https://fitmom.co
Free Constipation Care Guide: https://fitmom.co/CCG
Instagram: https://www.instagram.com/thepoopqueen/
Podcast: The Health Revival Show
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Coaching Website: https://www.warrior-makerscoaching.com/
Peptide Q&A #58 – Shelf Life, Drug Test, HGH vs IGF-1 LR3 & Carnivore Diet
2026/09/10
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover building muscle at 13.5% body fat, running carnivore diet on "R", St. John's Wort interactions, peptides for a marathon at 53, the mitochondrial stack sequenced properly, and whether IGF-1 LR3 and HGH can be run together.
Chapters:
00:00 – Intro & Holiday Weekend Recap
00:39 – Shark Stories & Ocean Safety Talk
07:35 – School, Coaching & Warrior Maker Updates
08:18 – Q&A: Muscle Gain & a Shredded Stomach (Age 43)
15:11 – Q&A: R & Fat Digestion on Carnivore
20:59 – Q&A: St. John's Wort & Peptide Interactions
24:39 – Q&A: KPV for Connective Tissue Disease
27:42 – Q&A: Low Energy on Tirzepatide & AOD (Age 38)
36:05 – Q&A: How Long Do Unmixed Peptides Last?
38:36 – Q&A: Do Peptides Show Up on Drug Tests?
40:35 – Q&A: Stacking HGH, CJC/Ipa & IGF-1 LR3
47:36 – Q&A: Marathon Training Stack After Major Weight Loss
51:40 – Q&A: Sequencing Mitochondrial Peptides for Energy (Age 55)
56:53 – Outro & New Hyperbaric Chamber Announcement
We cover:
• Building Muscle at 13.5% Body Fat as a Woman: Why eating more not less is the answer, why AOD should come out, and why 5-Amino-1-MQ, SLU-PP-332, and Tesamorelin-Ipa are the right additions
• Carnivore Diet on "R" with Ulcerative Colitis: Why high fat plus slow gastric emptying causes the problem, why small frequent meals fix it, and why a little fiber and 50 grams of carbs around training goes a long way
• St. John's Wort & "R" Interactions: Why R is broken down by protein enzymes not the liver's CYP450 system, why St. John's Wort is notorious for drug interactions, and why milk thistle, TUDCA, and glutathione are better liver support
• Mixed Connective Tissue Disease & KPV: Why oral BPC and KPV are generally safe to add, and why coming off a biologic requires a knowledgeable doctor not a podcast
• Low Energy on Tirzepatide at 133 Pounds: Why under-eating protein is the most likely culprit, why tracking macros is more powerful than any peptide, and why NAD, SS-31, MOTS-C, and methylated B12 are the right energy stack
• Lyophilized Peptide Shelf Life The Real Answer: Why unmixed peptides last up to two years in a cool dark place, why freezing creates moisture risk, and why the crisper drawer in a small fridge is all you need
• Do Peptides Show Up on a 5-Panel Drug Test: Why no standard workplace panel tests for peptides and why only high-level professional sports testing would even attempt it
• HGH vs IGF-1 LR3 — Can You Stack Both: Why CJC-Ipa is redundant once you're on HGH, when combining HGH and IGF-1 LR3 adds benefit vs. risk, and why MK-677 may be the smarter muscle-building add-on
• Marathon Prep Stack at 53 Down 87 Pounds: Why Wolverine is non-negotiable at this age and mileage, why Cardarine and SLU-PP-332 are the endurance game changers, and why adding HGH now gives it time to work before December
• Mitochondrial Stack for a 55-Year-Old Working at 2:30 AM: Why SS-31 comes first for at least two weeks, when to layer in MOTS-C, why NAD timing doesn't matter, and why Dihexa, magnesium glycinate, and glycine round out the protocol
You're a warrior. Act like one.
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Peptide Of The Week Website: https://peptideoftheweekpod.com
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Coaching Website: https://www.warrior-makerscoaching.com/
Peptide of the Week: ARA-290 & 5-Amino-1MQ – Nerve Pain & Fat Burning
2026/09/07
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas get back to basics and break down two compounds people have been asking about. ARA-290 for nerve pain and neuropathy, and 5-Amino-1MQ for fat burning and metabolic optimization. Two very different compounds with very different objectives.
Chapters:
00:00 – Intro & Show Plugs
02:37 – New Podcast Format Announcement
03:28 – ARA-290: Redefining Nerve Pain & Repair
05:09 – Nerve Injury Stories: Sciatica & Back Surgery
08:03 – How ARA-290 Works: Macrophage Reprogramming
13:15 – Dosing Protocols & Cost
15:47 – Nerve Pain, Surgery & Long-Term Nerve Damage
17:39 – Tips: Timing, Sleep, Nutrition & Exercise
22:23 – Side Effects, Safety & What to Stack With
24:59 – Compound #2: 5-Amino-1MQ for Fat Burning
27:32 – Real User Results & Fat Loss Data
30:00 – Dosing: Oral vs. Injectable & Cycle Length
33:16 – Zone 2 Cardio & Maximizing Fat Burn
37:37 – Stacking with GLP-1s & Breaking Plateaus
40:49 – Outro, Feedback & Next Episode Preview
We cover:
🧠 ARA-290 — Nerve Repair and Neuropathic Pain
– First discovered and researched in the early 2000s, still experimental but with human trials
– Selectively binds to the Tissue Protective Receptor (TPR) on immune cells, nerve cells, and metabolic tissues
– Reprograms macrophages from pro-inflammatory to anti-inflammatory, actually healing the nerve instead of masking pain
– Used for small fiber neuropathy, sarcoidosis, autoimmune nerve conditions, diabetic neuropathy, and post-viral recovery including long COVID
– Unlike painkillers, effects continue AFTER you stop taking it because it is healing the nerve, not just covering the pain
Real-world reports:
– Burning pain dropped from a 7 out of 10 to a 2 out of 10 within 3 weeks in diabetic neuropathy patients
– Mood lift and mental calm reported within 4 days (not the main intention but consistently reported)
– Nerve fiber density measurably increases over days to weeks
– Effects often persist 3 to 6 months post-cycle
What to stack with:
– BPC-157 and TB-500, NAD+, alpha lipoic acid, methylcobalamin, and B vitamins
What to avoid:
– NSAIDs and corticosteroids will blunt the effects
– Alcohol, high sugar, ultra-processed food, and chronic sleep deprivation all work against nerve healing
🔥 5-Amino-1MQ — The Fat Burning Compound
– Not a peptide, technically a small molecule compound. First developed around 2014
– Blocks NNMT (Nicotinamide N-Methyltransferase), which is massively upregulated in obese fat tissue and actively drives fat storage
– Blocking NNMT shifts your metabolism to burn fat instead of store it, essentially injecting keto without the diet
– Also replenishes NAD+ levels that have been depleted with age
– In animal studies: obese mice lost 7 to 9% of fat with no loss of lean muscle while eating the same amount of food
– Adds an additional 7 to 9% fat loss on top of GLP-1 results because it works on a completely different pathway
Who it is for:
– Anyone on a GLP-1 who has plateaued, this will relight the fire
– People with insulin resistance or pre-diabetes, it increases insulin sensitivity
– Already lean people looking to get even leaner and enhance body composition
– People with metabolic syndrome or NAD+ depletion
Best stacks: GLP-1 (especially R), MOTS-C, NMN, NAD+, L-Carnitine, Alpha Lipoic Acid, CoQ10
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Website: https://peptideoftheweekpod.com/
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Coaching Website: https://www.warrior-makerscoaching.com/
Is TRT Making Your Blood Too Thick? | Peptide Of The Week Q&A #57
2026/09/03
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover managing high hematocrit on TRT, why HDL drops on testosterone, navigating peptide social media censorship, peptide dosing math broken down simply, hair loss and DHT blockers, and protocols for insulin resistance and PCOS.
Chapters:
00:00 – Intro & School Platform Update
01:20 – Coaching Program Update & New Coaches
03:48 – Website Launch & Losing Social Media Channels
04:40 – Personal Life & Family Updates
07:13 – Upcoming Hawaii Trip
08:52 – Teaching Discipline: The Jax Story
12:23 – Q&A: Managing High Hematocrit on TRT
21:33 – Q&A: Insulin Resistance & Weight Loss
28:24 – Q&A: Peptide Dosing Math Explained
36:41 – Q&A: Navigating Social Media & Regulation
44:29 – Q&A: Low HDL on TRT
49:06 – Q&A: Adjusting Your Stack After Reaching Goal Weight
58:35 – Q&A: Hair Loss & DHT Blockers on TRT
1:07:24 – Q&A: Microplastics in Backwater Vials
1:10:14 – Q&A: PCOS, ACL Recovery & Building Muscle & Outro
We cover:
• High Hematocrit & Thick Blood on TRT: Why testosterone shuts off your body's governor on red blood cell production, why dehydration skews the reading, and why donating blood twice a year is the single best fix
• Insulin Resistance & Slow Fat Loss in Women: Why cardio is making it worse, why 40 grams of protein right when you wake up matters, and why walking 10 minutes after every meal may do more than any peptide
• Peptide Dosing Math Explained Simply: A live walkthrough of how to calculate exact milligrams per unit for GHK-CU, KPV, MOTS-C, C-Max, and "R" so nothing gets wasted
• Navigating Social Media Censorship as a Peptide Educator: Why JD's YouTube got pulled for a 10-minute fasting post, why algorithms are replacing human judgment, and why School and owned platforms are the only safe play
• Going Down on "R" After Reaching Goal Weight: Why 5 migs every two weeks makes no sense given the half-life, why 2-3x weekly dosing works better, and when to swap Tesamorelin for 2 IU of HGH
• Low HDL on TRT — What Actually Helps: Why niacin has been proven not to work, why aromatase inhibitors make it worse, and why mono-unsaturated fats and fasting are the real levers
• Hair Loss, DHT, Finasteride & Dutasteride: Why you're going to lose your hair if your family did regardless, why DHT blockers tank libido and mood, and Will's strategy of microdosing for 3 days to reset without the side effects
• Plastic vs. Glass Bacteriostatic Water Vials: Why benzyl alcohol pulls microplastics from plastic vials over time and why glass is the cleaner long-term choice
• 32-Year-Old Female with PCOS & ACL Tear: Why Tesamorelin-Ipa blend is the right starting point, why "R" at 500 mcg is virtually nothing, and why protein immediately after waking is non-negotiable
📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.
You're a warrior. Act like one.
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Coaching Website: https://www.warrior-makerscoaching.com/
Peptide of the Week: What's Really in Your Water – With Dani Carroll
2026/08/31
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Dani Carroll, a holistic health coach with 17 years of experience, Ayurvedic specialist, and yoga teacher. This one is not about peptides. It is about the thing most of us completely overlook that could be undermining everything else we do. Water.
Chapters:
00:00 – Intro & Meeting Dani Carroll
01:05 – Dani's Autoimmune Story & Failed Treatments
07:00 – Discovering the Water That Changed Everything
11:11 – First Results: Brain Fog, Joint Pain & Skin
13:00 – Testing It on Her Skeptical Parents
17:56 – Why Isn't Anyone Talking About Water?
19:17 – The Truth About Tap & Bottled Water
25:44 – How Bottled Water Degrades in Transit
27:47 – RO & Distilled Water: The Mineral Problem
29:46 – Understanding pH & the Alkaline Water Scam
34:06 – JD's GERD & Gut Health Case Study
41:19 – Chlorine, Showers & Skin Absorption
50:04 – How the Machine's Settings & Hydrogen Water Work
1:14:04 – Checking Your Own Tap Water (EWG Database)
1:21:13 – Five Rules for Drinking Water & Outro
We cover:
💧 Dani's story
– Autoimmune disease surfaced at 16, misdiagnosed with rheumatoid arthritis, full body joint pain and monthly skin peeling episodes
– Spent years going through every elimination diet, raw vegan, autoimmune paleo, nothing lasted beyond 90 days
– Gut microbiome destroyed by antibiotics prescribed by doctors who never addressed the root cause
– Discovered structured alkaline water during postpartum depression, within 45 days her skin stopped peeling for the first time in years
– 90 days in she was glowing. Her father lost weight, eliminated gout, and cleared acid reflux within months
🧬 Why water matters more than food
– You can survive 40 days without food. You die in 3 days without water. Yet nobody talks about water quality
– Tap water contains chlorine, fluoride, heavy metals, pharmaceuticals, forever chemicals, pesticides, and herbicides
– The chemicals in tap water are often added to protect aging city pipes, not to clean your water
– Water softeners add salt or potassium to protect your pipes, they are not designed to be consumed
– RO filtered water strips all minerals. Drinking it long term leaches minerals from your bones, causing bone density loss and eventually osteoporosis
– Plastic bottled water is dead water that sits in your stomach, does not absorb properly, and leaches microplastics
🚿 Your shower is a bigger problem than you think
– You absorb approximately one liter of water through your skin during a 10 to 15 minute hot shower
– Pores open in hot water, you inhale chlorine vapor, and your body absorbs it all
The 7 pH settings explained:
– 2.5 pH (hypochlorous acid): kills E. coli, MRSA, and bacteria. Use to sanitize meat, surfaces, and as mouthwash
– 11.5 pH (strong alkaline): veggie wash, makeup remover, skin treatment, poison ivy compress, eczema protocol. Neutralizes pesticides and herbicides which are designed to be water resistant
– 6.0 pH (beauty water): matches your skin and hair pH of 6.4. Use to wash your face and hair, works as a leave-in conditioner without stripping natural oils
– 7.0 pH (neutral): neutral rinse water for cooking and final food rinse
– 8.5, 9.0, 9.5 pH: drinking water levels depending on your health goals and tolerance
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Coaching Website: https://www.warrior-makerscoaching.com/
Follow Dani Carroll:
Instagram: https://www.instagram.com/rawsomeyoga/
TikTok: https://www.tiktok.com/@rawsomeyoga
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Can You Have A Baby While On TRT? | Peptide Of The Week Q&A #56
2026/08/27
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover why SS-31 has been a game changer for JD, how to properly sequence the mitochondrial stack, NAD reactions and replacements, when to come off R, building muscle at 12% body fat, fertility protocols while on TRT, and whether you really need to plan your protocols a year in advance.
Chapters:
00:00 – Intro & Personal Health Updates
03:06 – SS-31 & Finding the Right Protocol
06:04 – Disneyland Trip & Kids' Sports Talk
13:48 – Warrior Makers Coaching Program Launch
18:37 – School Platform Updates & Podcast Feedback
21:58 – Q&A: Sleep, Hormones & Energy for a Busy Mum
34:15 – Q&A: Major Weight Loss & a Bad NAD Reaction
39:07 – Q&A: Peptide Storage & Condensation
41:50 – Q&A: SS-31, MOTS-C & NAD Sequencing
49:31 – Q&A: Coming Off Retatrutide's Maintenance Dose
55:22 – Q&A: TRT & Fertility Protocols
1:08:14 – Q&A: Gut Health Flare-Up & Peptide Pause
1:14:53 – Q&A: Runner Wanting Muscle Over Fat Loss
1:21:14 – Q&A: Building a Smart Annual Peptide Plan
1:29:13 – Outro & Coaching Call Details
We cover:
• Why JD Is Feeling the Best He Has in Years: Why higher-dose SS-31 gets the credit, why less compounds often means feeling better, and why starting with two compounds and adding slowly is the smarter approach
• NAD Allergy What to Do Instead: Why reactions to NAD may come from the compound itself not just contamination, why SS-31 at five-plus megs is the closest alternative, and why blood work and hormone optimization should come first at 35
• Peptide Storage and Condensation on Vials: Why condensation on the outside of a vial does not mean moisture got inside, and why a dedicated mini fridge beats any canister solution
• Mitochondrial Stack SS-31, MOTS-C and NAD Sequenced Properly: Why SS-31 plugs the holes before MOTS-C revs the engine, why quarterly month-long SS-31 cycles make sense, and why NAD can run anytime regardless
• 42-Year-Old Australian Female Should You Come Off R: Why she probably doesn't need it at all, why 5-Amino-1-MQ and SLU-PP-332 are the right replacements, and why discipline is a better long-term tool than any GLP
• Fertility Protocol at 33 While Trying for a Baby: Why TRT doesn't have to stop, why HCG and Kisspeptin together improve fertility odds, and why Enclomiphene is the smarter choice over standard Clomid
• Building Muscle at 12% Body Fat and Running 60-70 Miles a Week: Why all that running is burning off the muscle she's trying to build, why cutting back to HIIT and lifting heavy is the real answer, and why low-dose testosterone may matter more than any IGF-1
• Total T of 420 at 43 Is It Time for TRT: Why 420 with low energy is answer enough, why TRT will change his life, and why planning protocols a full year out is overrated for most people
• How to Build a Smart Annual Protocol Without Overcomplicating It: Why JD and Will plan four months at a time, why trying too many compounds at once tells you nothing, and why the gateway compounds R and BPC are always the right starting point
📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.
You're a warrior. Act like one.
Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Coaching Website: https://www.warrior-makerscoaching.com/
Peptide of the Week: HRT, Peptides & Longevity With Dr. Ksenia
2026/08/24
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down virtually with Dr. Ksenia, known as Dr. K, a functional medicine doctor based in Miami who specializes in hormone replacement therapy, peptides, and weight loss. This one is packed with real clinical insight, especially for the ladies.
Chapters:
00:00 – Intro & Welcoming Dr. K
01:34 – Her Specialties: HRT, Peptides & Weight Loss
02:34 – Why Hormones Are Crashing in Young Men
05:57 – Why Doctors Skip Free Testosterone Testing
08:38 – Sleep, Food & Exercise: The Real Fix
09:48 – Women's Hormone Symptoms & Menopause Myths
14:07 – Finding Your Testosterone "Sweet Spot"
19:00 – Cream vs. Injection & What "Normal" Really Means
25:30 – Retatrutide vs. Tirzepatide for Inflammation
27:21 – Peptides for Athletes & Why BPC Is Banned
31:09 – Overhyped Peptides: MOTS-c, SS-31 & IGF-1 LR3
39:41 – The Ideal Longevity Stack & Real Healing Stories
49:42 – Muscle as the Foundation of Healthy Aging
54:53 – Fasting, Gut Health & Psychedelics
1:04:40 – Fertility Q&A, Dr. K's Personal Stack & Outro
We cover:
🧬 Why hormones are crashing in young people
– Post-COVID, many men saw testosterone drop significantly, viral illness and vaccines both suspected but no confirmed research yet
– Athletes with concussion histories frequently present with low testosterone due to trauma-induced endocrine dysfunction
– Excess body fat aromatizes testosterone into estrogen, tanking levels even in young men
– Free testosterone is the most important marker, not total, and most insurance doctors never run it
– A 12-minute appointment cannot solve a hormone problem, personalized medicine is the only answer
🦋 Women and hormones, the orchestra
– Women are not one hormone, they are estrogen, progesterone, testosterone, DHEA, and cortisol all working together
– Low estrogen symptoms: hot flashes, night sweats, mood swings
– Low progesterone symptoms: inability to stay asleep, anxiety, restlessness
– Low testosterone symptoms: zero libido, no motivation, no desire to train
– SSRIs are being prescribed for menopausal symptoms instead of hormones, which kills libido and solves nothing
– Menopause raises cholesterol because the liver keeps making it to synthesize hormones that are no longer being produced. Giving statins instead of hormones is the wrong answer
– Dr. K injects herself with 2 to 3mg of testosterone twice weekly and felt dramatically better within three weeks
💉 Testosterone for women
– Injectable testosterone at 10 to 15mg is well within normal female range and will not cause masculinization
– Creams work but require a higher concentration to hit therapeutic dose
– Compounded injectable estrogen (estrogen cypionate) is an option now that patch shortages are happening
– Pellets are not recommended by Dr. K, injectables or creams only
– Always monitor labs and adjust based on individual response
🔬 SS-31 vs MOTS-c, setting the record straight
– MOTS-c does not create more mitochondria, it reroutes energy. Dr. K has reviewed 80% of MOTS-c studies and finds no evidence it makes more mitochondria
– SS-31 stabilizes cardiolipin in the mitochondrial membrane, which is how ATP production is stabilized. This is the real deal
– Every person over 40 should consider SS-31 for longevity
Follow us on social media:
Will's Instagram: https://www.instagram.com/williamthaas/
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Follow Dr. K:
Instagram: https://www.instagram.com/dr.kseniamiami/
About Dr. K: https://kseniapetrushkina.com/
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Coaching Website: https://www.warrior-makerscoaching.com/
Is Your COA FAKE? | Peptide Of The Week Q&A #55
2026/08/20
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas are joined by peptide consultant Michael Vandal for a deep dive into peptide sensitivity reactions, how to spot a fake Janoshik COA, fixing cortisol and sleep, insulin resistance on secretagogues, and how to bulk while staying on R.
Chapters:
00:00 – Intro & How Michael Joined the Team
03:36 – Warrior Maker Coaching Program Launch
07:49 – More Than Fitness: Business & Community
08:28 – Personal Life Updates
10:28 – Q&A Begins
11:14 – Q&A: Peptide Hypersensitivity & Histamine Reactions
18:30 – Q&A: Adding Tessa to a Hyrox Athlete's Stack
23:13 – Q&A: How to Verify a Janoshik COA
26:10 – Q&A: High Estrogen & R Plateau (Age 57)
38:19 – Q&A: Cortisol, Water Retention & Sleep Fixes
48:12 – Q&A: Muscle Maintenance After Cancer Surgery
55:01 – Q&A: Do Collagen Peptides Actually Work?
58:52 – Q&A: Insulin Resistance & GLP Stacking
1:05:45 – Q&A: R Dosing for Bulking
1:13:06 – Q&A: Losing the Last 15 Pounds
1:17:10 – Outro & Coaching Program Reminder
We cover:
• Severe Peptide Sensitivity to CJC and Wolverine: Why blended peptides use a binding ingredient that some people are genuinely allergic to, why single peptides are the right next step, and why sourcing should be questioned first
• How to Verify a Janoshik COA and Spot Fakes: Why the unique code at the bottom is everything, how to verify it on Janoshik's site, and why photoshopped COAs always crop out that code
• 44-Year-Old HYROX Athlete — Add Tesamorelin or Go Straight to HGH: Why HGH wins at 44, why SLU-PP-332 helps endurance and nutrient partitioning, and why bumping Wolverine to at least 1 mig daily matters for athletes
• High Estrogen on TRT with No Symptoms: Why 1067 total T explains the elevated estrogen, why the three symptoms to watch for are the real indicator, and why an AI is not needed without symptoms
• Cortisol, Water Retention and Wrecked Sleep — Non-DSIP Solutions: The glycine, ashwagandha, magnesium glycinate and slow-release melatonin protocol that fixed JD's sleep, why Selank beats Semax for cortisol, and why Epithalon helps reset circadian rhythm
• Collagen Peptides — Do They Actually Work: Why powdered collagen supplements produce modest results at best and why BPC, TB-500 and GHK-CU are the real collagen peptides worth taking
• 53-Year-Old Female Post-Gastrectomy and Mastectomy: Why HGH and secretagogues are off the table, why SS-31 plus MOTS-C are the right longevity tools, and why creatine is non-negotiable for muscle preservation
• Insulin Resistance on Secretagogues: Why growth hormone peptides blunt insulin sensitivity over time, why pulling the secretagogue is the first move, and why an endocrinologist should be in the picture
• Bulking While on R: Why dropping to 1.5 migs every five days keeps food noise at bay while allowing enough appetite to eat for muscle, and why protein per pound of body weight is the only number that matters
• 27-Year-Old Down 80 Pounds — Last 15 to Lose: Why adding muscle is the only way to raise metabolism enough to drop the final pounds and why SLU-PP-332, 5-Amino-1-MQ and MOTS-C hit fat from three different angles
📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.
You're a warrior. Act like one.
Join The Community: https://www.skool.com/peptideresearchinstitute/about
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Peptide of the Week: Blood Work, Gut Health & Gear – With Dr. Scott Collie
2026/08/17
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with their personal functional medicine doctor and longtime friend, Dr. Scott Collie, for a deep dive into blood work, cardiovascular health, gut health, thyroid, and what actually matters when you are running gear or peptides.
Chapters:
00:00 – Intro: Dr. Scott & Talking Real Food (Italy Recap)
05:29 – The Truth About "Running Gear"
06:15 – TRT vs. Steroid Cycles Explained
10:22 – Why Bloodwork Timing Matters On vs. Off Cycle
12:58 – Blood Sugar, Insulin & GLP-1s
17:45 – Kidney, Liver & Iron Health Markers
22:25 – Understanding Cholesterol: LDL, HDL & VLDL
27:31 – Thyroid Health & Hashimoto's
30:06 – Homocysteine & Methylation
35:13 – Rapid Weight Loss & Gallbladder Risks
39:16 – Inflammatory Markers & Heart Damage Warning Signs
46:02 – Top Supplements & Peptides for Cycle Support
53:41 – Cycle Timing & When to Test Blood
1:01:51 – Hydration & Final Thoughts
1:06:07 – Outro & Where to Find Dr. Scott
We cover:
🩺What functional medicine actually looks at
– Standard doctor panels are a snapshot, not a full picture
– Dr. Scott runs up to 75 markers including cardiovascular, inflammatory, kidney, thyroid, and gut markers
– Most insurance doctors stop at LDL and HDL, missing the full story completely
– You need particle size, not just cholesterol weight, to understand your true cardiovascular risk
🫀 Cardiovascular markers that matter
– APOB: umbrella marker for all arteriosclerotic particles including VLDL, LDL, and IDL
– Particle size is critical: anabolic steroids shift particles to small dense LDL, the type that sticks and clogs arteries
– Myeloperoxidase and LP-PLA2: direct markers of vascular inflammation most doctors never run
– Triglycerides plus elevated liver enzymes (AST/ALT) almost always means fatty liver, no ultrasound needed
– Fibrinogen: a clotting protein made by the liver, high fibrinogen plus high insulin plus high triglycerides is a walking time bomb, especially for steroid users
– CRP (C-Reactive Protein): one of the best inflammatory markers available, if it is high something serious is going on
🧬Homocysteine, the underrated killer
– Homocysteine scars the inside of your arteries so plaque particles can park and stick
– Now being studied as an Alzheimer's marker as well
– Dr. Scott wants it at 7 or below, many people are at 9 to 50
– Fix: methylate with B6, B12, and methyl folate, simple and cheap
– TRT alone will elevate homocysteine, so methylating is a must for anyone on testosterone
⚖️Retatrutide and rapid fat loss, what to watch
– Losing fat very fast can back up bile flow and cause gallstones, not kidney stones
– Check alkaline phosphatase and GGT before starting Reta if there is any gallbladder history
– Signs of gallbladder issues: bloating, belching, pain under right rib cage, high-fat meal distress, floating stools
– Floating poop is not a good sign, it means fat is not being absorbed properly
– Blood sugar, triglycerides, and inflammatory markers improve dramatically and quickly on Reta
🩸Blood work timing for gear users
– Best time to test: before the cycle starts, to establish your baseline
– After the cycle ends: retest to confirm you returned to baseline
– Mid-cycle testing will look alarming by design, be ready for that
– If you do not know what different esters are, you are not ready to run gear
Follow Dr. Scott Collie:
Website: https://heydrscott.com/
Facebook: https://www.facebook.com/DrScottCollie/
Instagram: https://www.instagram.com/hey_dr_scott/
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Follow us:
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Peptide Q&A #54 – Peptide Blends Achilles Surgery Recovery, Adderall Detox & HGH vs IGF-1
2026/08/13
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover Achilles tendon surgery recovery, why CJC histamine reactions are increasing, getting off Adderall at 18, switching from Tirzepatide to Retatrutide, running HGH with IGF-1 LR3, and whether peptide blends really mix evenly.Chapters:00:00 – Intro & Warrior Makers Coaching Launch03:56 – Building Better Men & YouTube Ban Update06:15 – Where to Find the Podcast (Spotify, Rumble & More)07:27 – Upcoming Guest: Water & Hydration08:57 – School Platform & Free Resources09:51 – Q&A: Peptides for Achilles Surgery Recovery (Age 68)13:51 – Q&A: Switching CJC/SS31 for Muscle Gain (Age 41 Female)21:16 – Q&A: Getting Off Adderall Safely (Age 18)27:34 – Q&A: Transitioning from Tirzepatide to Retatrutide33:27 – Q&A: Do Wolverine Blend Ratios Mix Evenly?37:21 – Q&A: Running IGF-1 LR3 with HGH40:17 – Q&A: Best Stack When Cycling Off Retatrutide44:17 – Q&A: Low Sex Drive, LH & HCG Protocol (Age 44)52:28 – Q&A: Cutting Body Fat Before Vacation (Age 33)56:19 – Q&A: HGH vs IGF-1 for Lean Muscle (Age 42 Female)59:44 – Outro & Coaching Call ReminderWe cover:• Achilles Surgery Recovery for a 68-Year-Old: Why starting Wolverine three weeks before surgery matters, why hyperbaric chambers expedite healing, and how to keep her moving without overdoing it• CJC Histamine Reactions Are Increasing: Why JD is hearing more and more bad reactions and why switching to Tesamorelin is the smarter, safer move for women• Tesamorelin Dosing for Women: Why 500 micrograms is the right starting point, why bumping in 250 mcg increments prevents water retention, and why AOD stacked with Tessa transforms women's bodies• 18-Year-Old Getting Off Adderall: Why C-Max, Tesofensine and Dihexa are the peptide answer and why getting off drugs isn't pain-free no matter what you take• Tirzepatide to Retatrutide Transition for a HYROX Athlete: Why pulling the band-aid and starting at 3 migs works, why SLU-PP-332 helps with nutrient partitioning and endurance, and why Thymosin Alpha-1 handles inflammation• Do Peptide Blends Mix Evenly in the Syringe?: Why aqueous solutions mix uniformly unlike oil and water and why this concern is probably overthinking it• HGH vs IGF-1 LR3 Can You Run Both?: Why JD runs them together regularly, why there's no definitive proof it's dangerous, and why HGH alone already blows away any secretagogue• Should You Take Breaks from Retatrutide?: Why tolerance builds over time, why Tesofensine is a good weaning tool, and why building your base means you shouldn't need it forever• Police Officer at 21% Body Fat Getting Ripped: Why HCG should run alongside TRT, why MK-677 may be a better choice than HGH right now, and why fasting is the most underrated tool for men over 40• 42-Year-Old Female with No IGF-1 Response to Secretagogues: Why timing before blood draw skews results, why 1 IU of HGH is the cleanest answer, and why AOD plus Tesamorelin is the best women's fat-burning duoYou're a warrior. Act like one.
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/aboutSubscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Podcast reviews
Read Peptide of The Week podcast reviews
GWillyD 2026/08/27
Enjoyable Pep Listening
After one listen you’re hooked. The greatness is half the information they’re providing and half the genuine friendship of JD and Will. I feel like ...
Shadysgc 2026/07/27
Go to podcast.
Good listen, entertaining!
Peptide Supply Co. -Code PEPTIDE
geriffic 2026/06/26
Likeable guys but you can find better
There are like, I don’t know, 10 folks in this space worth listening to. These guys are above average and the people who submit questions are often sm...
pumper nickel 2026/06/26
Fav Pod
Best peptide podcast by far, but for the love of God please turn down the commercials.
Jriefkrisb 2026/05/18
New peptide
Will needs a peptide for his cough. Or just a cough button
Fffyyyyytttt 2026/04/07
Info
Love the podcast great info for starting my journey and only diving deeper into the peptide world! You guys are killing it on here! I appreciate all t...
Zaidanator 2026/04/03
Love the Q&A’s
Great show, informative, honest, helps keep me up to date in the peptide world. More guests would be great. Maybe athletes from different sports shari...
MiamiNative70 2026/03/03
Just easy
Easy to comprehend, layman’s terms, quality information, real world practical approach to applied research.
crownjewel602 2026/01/13
New listener
I recently came across the pod and it’s super informative. I appreciate the content. Keep up the good work.
First time listener  2026/01/06
Peptide of the week
Five minutes in after talking about video games and your kids and everything besides what I come to listen to you lost me never did hear the podcast f...
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