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Full show notes: BenGreenfieldLife.com/thymuspodcast In this episode, I sit down with internal medicine physician Dr. Abud Bakri to talk about the thymus, the small gland on top of your heart that trains your immune system and starts shrinking as soon as you hit puberty. You’ll hear what speeds that shrinkage up, from birth control and testosterone therapy to chronic infections, stress and a leaky gut, why Korean eunuchs lived longer, and which blood markers, like the ratio of helper to killer T cells (CD4-to-CD8 ratio), give you a window into how your thymus is doing. We get into thymulin and zinc, thymosin alpha-1, the Russian thymus extract Thymalin, and whether eating sweetbreads does anything at all. You’ll also hear my bedtime stack of epitalon and Pinealon, why Abud shines red light on his sternum, the overlooked link between the thymus and testosterone, why he takes 40 times my dose of body protection compound 157 (BPC-157) for injuries, and the red flags to watch for before you inject any peptide. We also cover natural killer cell treatments, the libido peptide being tested for weight loss, and why Abud thinks lactoferrin and colostrum are about to catch on. Episode Sponsors: Hiya: Full-body nourishment for your kids with Hiya’s best-selling children’s vitamin. Get 50% off your first order at hiyahealth.com/BEN (it is not available on their regular website). Tecton Ketones: Bioidentical D-beta-hydroxybutyrate (BHB), the same ketone your body makes during ketosis, for clean cognitive support, stable energy, and performance. Visit tectonketones.com/ben and use code BEN for 16% off your first order. Timeline: Mitopure unlocks a precise dose of the rare Urolithin A molecule to give your cells new life and promote healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN. Qualia Stem Cell: A science-backed supplement that supports your body’s natural repair system by enhancing stem cell function, taken just four days per month. Visit qualialife.com/boundless and use code BOUNDLESS for 15% off. Manukora: Honey with superpowers, unlike any honey you’ve tasted or seen before. Head to manukora.com/ben or use code BEN and you’ll automatically get $25 off your Starter Kit. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/lowcarbhighcarb In this episode, I'm re-airing the first debate ever held on the Boundless Life podcast, with repeat guest Jay Feldman and Duke obesity medicine physician Dr. Eric Westman going head to head on whether your cells run better on carbohydrates or fat. The carbs-are-good, carbs-are-bad argument has only gotten louder, and this is still the best version of it I've heard. You'll hear Jay's case that burning fat creates more oxidative stress and drives up stress hormones like glucagon and cortisol over time, and Eric's case from decades of reversing type 2 diabetes in his clinic. We get into the KetoSAge study that pulled keto-adapted women out of ketosis, the KETO Trial on keto dieters with very high LDL cholesterol, what a failing heart actually burns, and why keto adaptation can take months. We close on the membrane pacemaker theory of aging, survival versus thriving, how I scale my own carbs to training and travel, and the three carb levels Eric lays out in End Your Carb Confusion. Whether you eat keto, high-carb, or somewhere in between, this debate will sharpen how you think about fuel. Episode Sponsors: Forkful: Chef-cooked, ready-to-eat meals made with premium ingredients and zero seed oils, delivered fresh and ready in under 3 minutes. Visit ForkfulMeals.com and use code BEN50 for 50% off your first order. Just Thrive: A spore-based probiotic with four strains designed to survive digestion and support a healthy gut. Start a 90-day probiotic subscription and get a free 90-day supply of their Digestive Bitters, a $90 value. Visit get.justthrivehealth.com/pages/ben to claim the offer. Dr. Murray Natural Products – ThymoQuin®: A clinically researched black seed oil formulated to support healthy cortisol levels and resilience to everyday stress. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products. Tiny Health: An at-home microbiome test with personalized, evidence-based recommendations based on your results. Get $50 off your first at-home test kit at TinyHealth.com/BEN. Xtendlife Prosta Support Advanced: A daily prostate support formula with saw palmetto, beta-sitosterol, and botanicals. Visit bengreenfieldlife.com/xtendlife and use code GREENFIELD for 15% off your order. Nuchido: Nuchido TIME+ supports NAD production, recycling, and preservation for healthy aging at the cellular level. Visit BenGreenfieldLife.com/Nuchido and use code BEN20 to save 20% on your order. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/thyroidhealth In this episode, I'm re-airing one of the most comprehensive thyroid conversations I've ever had, with repeat guest Dr. Amie Hornaman. Six doctors told her she was normal while she gained 25 pounds in contest prep, and the seventh finally found the goiter. You'll hear why thyroid stimulating hormone (TSH) on its own misses most of the picture, how reverse T3 can block your active thyroid hormone at the cell door, and why only 2% of hypothyroid patients do well on T4 alone. We get into T2, the thyroid hormone almost nobody talks about, and the Thyroid Fixxr® (use code BEN10 for 10% off) I took to Italy. Dr. Amie also covers what years of low-carb eating does to T3, whether animal glandulars help or backfire, where iodine and selenium fit, the peptides she uses for Hashimoto's, and why testosterone matters so much for women. If you've been told your thyroid labs are normal and you still feel terrible, this one is for you. Episode Sponsors: Our Place: Upgrade to Our Place today and say goodbye to forever chemicals in your kitchen. Go to fromourplace.com/ben and enter my code BEN at checkout to receive 10% off sitewide. Larine: A better-for-you chewing gum with nano-hydroxyapatite, the same mineral your tooth enamel is made of, to support stronger teeth and fresher breath. Visit BuyLarine.com/BEN to get up to 50% off your order today. TruDiagnostic: An at-home epigenetic test that measures over a million biomarkers for personalized insights into your aging, energy, and health. Visit TruDiagnostic.com and use code BEN20 for 20% off. ULTRA: A clean, nicotine-free, and caffeine-free pouch for smooth, sustained energy and focus without the jitters or crash. Visit takeultra.com and use code BENGREENFIELD for 15% off. Young Goose: Cutting-edge skincare products. Visit younggoose.com and use code BGF10 at checkout for 10% off your order. Active Skin Repair: Non-toxic skin support with hypochlorous acid, a molecule your body naturally produces. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/ultimatelongevity In this episode, I'm pulling the best of three longevity conversations into a best-of compilation: blood oxygen as the root of nearly every disease pathway, the molecule that clears out your worn-out mitochondria, and a 61-year-old engineer who is out-aging tech billionaires on a normal budget. All three come at the same problem from completely different directions. First, Gary Brecka on what two decades of predicting death for life insurance companies revealed, why he says the presence of oxygen is the absence of disease, and the magnetism, oxygen and light protocol he built out of it, including a budget version of exercise with oxygen therapy you can do with a training mask. Then Dr. Anurag Singh on the three ways your immune system ages, why he thinks immune aging drives the rest of aging, and what the Mito-Immune trial found when middle-aged adults took Mitopure® (use code BEN20 for 20% off) for four weeks. And finally Dave Pascoe, who got the telomeres of a 68-year-old at age 50, turned it around, and now posts a pace of aging near the top of the Rejuvenation Olympics leaderboard while eating two meals at a sitting and taking no testosterone. I also share the red light routine I run for the first hour of every morning. Episode Sponsors: Sunlighten: Patented near-, mid-, and far-infrared sauna technology to reduce inflammation, boost mitochondrial function, and optimize recovery. Save up to $1,600 at get.sunlighten.com/ben with code BEN. Quantum Upgrade: Research shows the Quantum Upgrade increased ATP production by 20–25% in human cells. Unlock a 15-day free trial with code BEN15 at quantumupgrade.io. BIOptimizers Magnesium Breakthrough Advanced 10: 10 bioavailable forms of magnesium with active vitamin B6 and ionic trace minerals for sleep, recovery, stress, and metabolic health. Go to bioptimizers.com/ben and use code ben15 for 15% off any order. Tecton Ketones: Bioidentical D-beta-hydroxybutyrate (BHB) for clean cognitive support and stable energy without the conversion step. Visit tectonketones.com/ben and use code BEN for 16% off your first order. BON CHARGE: Holistic wellness products to help you sleep better, recover faster, balance hormones, and reduce inflammation. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/drtyna I'm re-airing my conversation with Dr. Tyna Moore about GLP-1s because almost everything she said about them is still being misunderstood, and she was one of the earliest voices advocating for using these drugs at very low doses. When we recorded, the internet had largely decided GLP-1 agonists were terrible: muscle wasting, "Ozempic face," suicidality, and more. Tyna's take was very different, and much of what she discussed has held up surprisingly well. Not everything, though. The big Alzheimer's trials found that GLP-1 treatment did not significantly slow disease progression. I was the guinea pig for this one. The week before our interview, I injected one-tenth of the standard semaglutide dose, and Dr. Moore told me on air that even that was far too much for me. She was right. It took me three days to get through one porterhouse steak. You'll hear what dosing for appetite control rather than appetite suppression actually looks like, why a natural GLP-1 stimulator may not do much if the gut cells that release GLP-1 have stopped responding, what the thyroid cancer black box warning is actually based on, what that widely shared suicidality study really measured, and how to protect your muscle while using these drugs. Dr. Tyna Moore also shares where she sends people now that she has stopped taking new patients, which is The Menopause Rebellion, her community for Gen X women covering hormones, metabolism, muscle building, GLP-1s, and peptides. Episode Sponsors: ALYA Health: A high-polyphenol, single-origin olive oil made from rare Tunisian Chetoui olives, designed to be taken as a daily shot before a meal. Visit AlyaHealth.com/s/ben or use code BEN for 20% off your first order. JOYMODE: Want to spice things up in the bedroom, boost your sexual performance, and do it naturally without nasty prescription drugs? Visit tryjoymode.com/BEN or enter BEN at checkout for 20% off your first order of JOYMODE. ULTRA: A clean, nicotine-free, and caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters or crashes. Visit takeultra.com and use code BENGREENFIELD for 15% off. Dr. Murray Natural Products – ThymoQuin®: A clinically researched black seed oil that supports healthy cortisol levels and resilience to everyday stress. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/AGIpodcast In this episode, you'll hear how artificial intelligence is actually being pointed at aging right now, including an algorithm picking which Chinese herbs extend a fruit fly's life, plus whether the biological age test you just paid for means anything at all. My guest is Dr. Ben Goertzel, who popularized the term artificial general intelligence, runs a decentralized AI network, and is chief scientist at Hanson Robotics. We get into the long-lived fruit flies his team works on at Genescient, the roughly five traditional Chinese herbs an AI selected from a database and combined in ways that more than double a middle-aged fly's life, and why the AI mixes them in combinations no Chinese medicine practitioner ever would. You'll also learn why he says today's biological age tests are "a little dodgy," why large language models keep handing you the existing literature instead of generating new science, and what the extracellular matrix has to do with whether your whole body is aging well. We close on the engineered enzymes he thinks will eventually re-sculpt the genome of every tissue in your body, my own follistatin gene therapy result, and the band he plays keyboards in with a humanoid robot lead singer. Episode Sponsors: Dr. Murray Natural Products – ThymoQuin®: A clinically researched black seed oil formulated to support healthy cortisol levels and resilience to everyday stress. It's the only black seed oil that meets U.S. Pharmacopeia guidelines. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products. Young Goose: To experience the transformative power of Young Goose's cutting-edge skincare products, visit younggoose.com and use code BGF10 at checkout to enjoy a 10% discount on your order. ALYA Health: A high-polyphenol, single-origin olive oil made from rare Tunisian Chetoui olives and designed to be taken as a daily shot before a meal. Visit AlyaHealth.com/s/ben or use code BEN for 20% off your first order. Active Skin Repair: Uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS. Nuchido: Support healthy aging at the cellular level with Nuchido TIME+, designed to optimize your body's NAD (nicotinamide adenine dinucleotide) metabolism across multiple pathways rather than a single ingredient. Visit BenGreenfieldLife.com/Nuchido and use code BEN20 to save 20% on your order. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/506 In this episode, you'll discover three things I've been asked about constantly: whether the melatonin heart failure headline is worth worrying about, how much sleep is actually too much or too little, and the shortest route to a higher VO2 max. I break down what the melatonin study did and did not reveal, why a key prescription detail changes how the findings should be interpreted, and why I still use high-dose melatonin for jet lag. Then I move to VO2 max, including the Norwegian 4x4 explained the way I used to coach it, what the sprint interval research says about doing it faster, and the tools that work beyond exercise, from heat acclimation to altitude to correcting an iron deficiency. You'll also hear what a new Nature study of half a million people found about the 6.4 to 7.8 hour sleep window, and why I still sleep less than that on purpose. Finally, fertility for men and women. On the male side, scrotal temperature, timing intercourse around ovulation, the lubricant problem nobody mentions, and the supplements with real human data behind them, from L-carnitine and CoQ10 to zinc and shilajit (use code GREENFIELD for free shipping). On the female side, ovulation tracking, acupuncture, CoQ10 before egg retrieval, and inositol. Plus how to preserve fertility if you're on testosterone replacement therapy (TRT). Episode Sponsors: BIOptimizers Magnesium Breakthrough Advanced 10: Ten bioavailable forms of magnesium with active vitamin B6 and ionic trace minerals to support uptake, sleep, recovery, stress, and metabolic health. Go to bioptimizers.com/ben and use code BEN15 for 15% off any order. Timeline: Give your cells new life with Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule. Mitopure now starts at $79 at timeline.com/BEN. ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters or crashes. Visit takeultra.com and use code BENGREENFIELD for 15% off. Tiny Health: An at-home microbiome test that analyzes your full gut ecosystem and gives you personalized, evidence-based diet and supplement recommendations. Get $50 off your first kit at TinyHealth.com/BEN. Active Skin Repair: Uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/gutsolution In this episode, you'll meet Josh Dech, a former paramedic turned Crohn's and colitis consultant who argues that all three things Western medicine says about inflammatory bowel disease are wrong: it's not genetic, not classically autoimmune, and not idiopathic. We walk the research trail from a 1988 Swedish twin study through the NOD2 gene to the genome-wide studies that mapped hundreds of risk loci and still explained only a sliver of the disease, and into the numbers that worry him most, where the West has 6% of the world's population but 60% of its bowel disease. You'll also get the practical half: his sequence to help stop the active cause first, then how he suggests opening the seven drainage pathways, why he takes a full history before ordering a single test, where peptides belong, what is really coming out of people during a parasite cleanse, and why $30,000 fecal transplants keep failing. Near the end, it turns personal and a little gross, into my own dairy problem and the biomechanics of a proper bowel movement. Episode Sponsors: Quantum Upgrade: Boost your cellular energy, wherever you are, with a field shown to increase ATP (adenosine triphosphate) production by 20 to 25 percent in human cells. Get a 15-day free trial at quantumupgrade.io with code BEN15. TruDiagnostic: An at-home epigenetic test that measures over a million biomarkers and turns them into a clear picture of how you are actually aging. Visit TruDiagnostic.com and use code BEN20 for 20% off. Dr. Murray ThymoQuin®: The only black seed oil that meets U.S. Pharmacopeia guidelines, clinically researched to support healthy cortisol levels and everyday stress resilience. Visit doctormurray.com/ben and use code BEN25 for 25% off. Manukora: Honey with superpowers, and unlike anything you have tasted before. Head to manukora.com/ben or use code BEN and you'll automatically get $25 off your Starter Kit. Active Skin Repair: Uses hypochlorous acid, a molecule your body already makes, to support skin repair without harsh chemicals. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS. Nuchido: Nuchido TIME+ supports multiple pathways in NAD production, recycling, and preservation rather than relying on a single ingredient. Visit BenGreenfieldLife.com/Nuchido and use code BEN20 to save 20%. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/limitlessdaily In this episode, you'll hear repeat guest Jim Kwik talk about cognitive offloading and where the line sits between using your phone as a second brain and letting your own memory go slack. We dig into the MIT study that scanned essay writers' brains and found the ChatGPT group remembered the least of what they wrote, what London cabbies' brains looked like before satellite navigation, why movement drives brain-derived neurotrophic factor (BDNF), and why racket sports and dance sit at the top of the longevity list. You'll also learn Jim's BUILD framework for using AI as a critic rather than an answer machine, how to write an affirmation your brain will not immediately reject, the white bear effect that makes "don't check your phone" the least useful instruction you can give yourself, why the 15 to 45 minutes of sleep inertia after you wake carries more weight than any other window in your day, and the four daily basics Jim ranks above every device in his house. We close with the 40 Hz gamma protocol I now use in the early afternoon, and the surprising effect it's had on how quickly I fall asleep at night. All of this comes straight out of Jim's new book, Limitless Daily, designed to give you one simple, actionable lesson each day for an entire year. Episode Sponsors: Tecton Ketones: Bioidentical D-beta-hydroxybutyrate (BHB), the same ketone molecule your body makes in ketosis, for clean cognitive support and stable energy with no conversion step. Visit tectonketones.com/ben and use code BEN for 16% off your first order. ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth energy and focus from clinically backed nootropics and adaptogens, with no jitters or crashes. Visit takeultra.com and use code BENGREENFIELD for 15% off. Forkful: Chef-cooked, ready-to-eat meals made with grass-fed bison, wild-caught salmon, and fresh vegetables, zero seed oils, no prep and no cleanup, ready in under 3 minutes. Visit ForkfulMeals.com and use code BEN50 for 50% off your first order. Just Thrive: The Gut Essentials Bundle pairs a probiotic clinically proven to arrive 100% alive in your gut with Digestive Bitters, 12 science-backed herbs that support digestion and GLP-1 production. Visit justthrivehealth.com/BEN and save 20% with promo code BEN. See omnystudio.com/listener for privacy information.

Full show notes: BenGreenfieldLife.com/jubilee In this episode, John Jubilee makes the case that almost everything you have been told about hydration is beside the point. His argument is that the water is not the problem, the cell is: that a membrane gets progressively harder to penetrate as you age, that your water and your supplements simply bounce off it, and that until you change the membrane itself, nothing else you do gets in. He arrived at that after a decade of doing everything right, a gallon of water a day and a thousand dollars a month in supplements, and still having high blood pressure and no cartilage left in either knee.  You'll hear the question he asked every one of his doctors that none of them could answer, the $11,000 machine he bought in 1997 to answer it himself, and the Energized Health protocol he built out of it. You'll also get the practical layer that costs nothing: the three steps he tells everyone to start with, the balls-of-your-feet walking trick and the soleus study behind it, his case for MSM, and why he refuses to recommend alkaline, structured, or reverse osmosis water. Then it turns personal, into cellular trauma, the ACE study, and why he believes a flawless diet still leaves something unaddressed. Mention Ben's name on your free breakthrough call with Energized Health for 40% off the 88-day program. Episode Sponsors: BIOptimizers Magnesium Breakthrough: Most magnesium supplements give you one or two forms. Magnesium Breakthrough gives you all seven, in the ratios your body actually uses, so you get better sleep, calmer nerves, and steadier energy. Go to bioptimizers.com/ben and use code BEN15 for 15% off any order. Dr. Murray ThymoQuin®: Black seed oil has been used for thousands of years, and ThymoQuin® is the most concentrated, highest-quality form of it available. It supports your immune system, your metabolism, and healthy inflammation levels. Visit doctormurray.com/ben and use code BEN25 for 25% off. ULTRA: A clean, functional performance drink with no artificial sweeteners, no seed oils, and no junk. Get it at bengreenfieldlife.com/ultra or takeultra.com and use code BENGREENFIELD for 15% off. Our Place: Nontoxic, PFAS-free cookware that replaces the whole cabinet with a few pieces you'll actually use. Go to fromourplace.com/ben and use code BEN for 10% off sitewide. Quantum Upgrade: Boost your cellular energy, wherever you are, with a field that works on you, your home, and even your car. Get a 15-day free trial at quantumupgrade.io with code BEN15. See omnystudio.com/listener for privacy information.

Full show notes: bengreenfieldlife.com/bolt In this episode, Chandler Bolt and I talk about how we've each landed on almost identical daily systems for running a company, and the one place we still disagree. Chandler makes the case that a book is a business asset rather than an income stream, explains what it actually costs to buy your way onto the New York Times list, and then walks through the routine underneath all of it: a nap he hasn't skipped in years, a morning he refuses to let anyone schedule over, and a phone that geofences itself into work mode the moment he arrives at the office. You'll also hear why he self-experiments relentlessly yet refuses to wear a tracker. We get into the two metrics worth watching if you track nothing else, why the 30-minute nap ceiling is weaker science than you've been told, why a hot tub is harder on fertility than a sauna, what overhead LED lighting does to your afternoon and the BlockBlueLight bulbs I use instead, and why a manual WALKOLUTION treadmill desk beats a motorized one. Chandler also shares the airplane movement trick that got him mistaken for a lunatic by a stranger who later became a friend. Then we close on communication: being a default no, replacing calls with voice memos, and using SocialSweep to surface the connections already sitting in your phone. Episode Sponsors: TruDiagnostic: TruDiagnostic is an advanced at-home test that uses epigenetic analysis to measure over a million biomarkers, giving you personalized, data-driven insight into your aging, energy, and overall health. Visit TruDiagnostic.com and use code BEN20 for 20% off. Fatty15: Fatty15 is on a mission to optimize your C15:0 levels and help you live healthier, longer. Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/BEN and using code BEN at checkout. Young Goose: To experience the transformative power of Young Goose's cutting-edge skincare products, visit younggoose.com and use code BGF10 at checkout to enjoy a 10% discount on your order. Larine: Larine's better-for-you chewing gum uses nano-hydroxyapatite, the same mineral your tooth enamel is made of, to support stronger, healthier teeth while freshening your breath. Visit BuyLarine.com/BEN for up to 50% off your order today. Sunlighten: Sunlighten's patented infrared sauna technology delivers the highest quality near-, mid-, and far-infrared wavelengths to reduce inflammation, boost mitochondrial function, enhance detox pathways, and optimize recovery. Save up to $1,600 at get.sunlighten.com/ben with code BEN. Nuchido: Support healthy aging at the cellular level with Nuchido TIME+, designed to optimize your body's NAD metabolism across multiple pathways rather than relying on a single ingredient, for healthy energy, cognitive function, and recovery. Visit BenGreenfieldLife.com/Nuchido and use code BEN20 to save 20%. See omnystudio.com/listener for privacy information.

Full show notes: bengreenfieldlife.com/pharma In this special repeat episode, Dr. Sandra Kaufmann breaks down which pharmaceuticals mimic the effects of things you already do for your health: what replaces a sauna session, what replaces a fast, what replaces a cold plunge (use code BENFORGE for $500 off select products), and what she takes with meals to blunt the damage from glucose spikes. I'm re-airing it now because of a new Nature paper finding that lithium is a naturally occurring brain nutrient, and that losing it may be one of the earliest steps toward Alzheimer's, at a dose in exactly the range Dr. Kaufmann described on this show years earlier. You'll hear why she prefers pioglitazone over metformin for autophagy, how a Japanese gastritis drug connects to Alzheimer's, and how she worked her way up on an emergency blood pressure medication, starting at a dose that nearly knocked her off her feet and climbing to 100mg with no effect at all. The centerpiece is lithium (code BGL10 for 10% off): why the doses hidden inside popular nootropics are a fraction of what she considers useful, and everything it appears to do beyond mood, from controlling a pore in your mitochondria to building bone and growing new neurons. You'll also get her honest take on gene therapy versus pharmaceuticals, why peptides underperform in an older cell, and which molecule finally knocked astaxanthin off the top of her ranking system. Episode Sponsors: Xtendlife Prosta Support Advanced: A comprehensive daily prostate support formula combining saw palmetto, beta-sitosterol, vitamins, minerals, and botanicals to support prostate health, urinary function, and healthy aging. Visit Xtendlife.com/BensChoice and use code GREENFIELD for 15% off your order today. BON CHARGE: BON CHARGE is a holistic wellness brand whose products help you sleep better, perform better, recover faster, balance hormones, and reduce inflammation. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%. Tecton Ketones: Tecton Ketones deliver bioidentical D-beta-hydroxybutyrate (BHB), the same ketone molecule your body produces during ketosis, for clean cognitive support and stable energy with no conversion step. Visit tectonketones.com/ben and use code BEN for 16% off your first order. Dr. Murray Natural Products – ThymoQuin®: ThymoQuin® is a clinically researched black seed oil formulated to support healthy cortisol levels, improve resilience to everyday stress, and promote overall well-being. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products. Hiya: Give your kids the full-body nourishment they need to grow into healthy adults. I've secured a special deal with Hiya on their best-selling children's vitamin, 50% off your first order. Go to hiyahealth.com/BEN (it is not available on their regular website). See omnystudio.com/listener for privacy information.

Full show notes: bengreenfieldlife.com/505 In this solosode, you'll get the latest on microplastics, spinal disc health, and what a heart scan sees that a cholesterol panel misses. A new seven-day trial pitted five plastic-avoidance strategies against each other, and the results tell you exactly where to spend your effort if you can't overhaul everything at once. You'll hear which plastic sources matter most and what I now take before bed with BrocElite® (use code BEN for 25% off your first month) to help clear microplastics from tissue. Then I get personal about my back. I'll walk you through my full-body MRI results, which show significant degeneration from L1 to S1, and explain why I still have almost zero back pain, from Dr. Stuart McGill's Big 3 to inversion hanging, the couch stretch, the founder stretch from Foundation Training, and my WALKOLUTION® treadmill desk ($100 off, enter your email for a unique code). You'll also learn why running was the only activity linked to healthier spinal discs in a study of more than 4,000 people, and why none of the sports people assume are hard on your back showed harm. Finally, you'll hear what a coronary CT angiography measures that your cholesterol panel cannot, why a 6,061-person study found plaque volume beats any standard risk calculator, what my own scan revealed, and the surprisingly simple thing that appears highly protective even when your plaque is already elevated. Episode Sponsors: ULTRA: ULTRA is a clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters, crashes, or sleep disruption. Visit takeultra.com and use code BENGREENFIELD for 15% off. Forkful: Forkful delivers chef-cooked, fresh, ready-to-eat meals made with premium ingredients like grass-fed bison and wild-caught salmon, with zero seed oils and no prep or cleanup, ready in under 3 minutes. Visit ForkfulMeals.com and use code BEN50 for 50% off your first order. Quantum Upgrade: Recent research revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20 to 25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Supzential: More Than a Toothpaste: Created by biological dentist Dr. Dome, it combines highly bioavailable hydroxyapatite, a patented probiotic, xylitol, and lactoferrin to support enamel remineralization and a healthy oral microbiome, with no fluoride, SLS, or titanium dioxide. Visit Supzential.com and use code BEN20 for 20% off your order today. Active Skin Repair: Active Skin Repair uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals, from post-workout irritation to everyday skin support. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS. See omnystudio.com/listener for privacy information.

Full show notes: https://bengreenfieldlife.com/holyhealth In this episode with Justin Roethlingshoefer, you'll hear from a former NHL performance coach turned health entrepreneur whose new book, Holy Health, is the one I chose for my father-son book club this month. This is not another eat-honey-and-drink-milk Bible health book. Justin is a genuine biohacker who works with pro athletes worldwide, and he has woven deep spiritual and physiological science into the same framework. You'll learn why the modern obsession with optimization can quietly become idolatry, how the drive to control your metrics keeps your nervous system stuck in fight-or-flight and lowers your HRV, and the five "hearts" that trap high performers in striving. You'll also get the practical side: his full morning and evening rhythms, why he starts his day at 6 p.m. rather than at sunrise, the breathwork he does midday in the grass, his exact zone two and zone five weekly targets, and how he folds three and a half hours of zone two into family walks with a weighted vest. It's a conversation about doing less frantic optimizing and more intentional stewardship, and it may reframe how you think about every biohack you own. Episode Sponsors: Tiny Health: An at-home microbiome test that uses metagenomic sequencing to analyze your full gut ecosystem and give personalized, evidence-based diet, lifestyle, and supplement recommendations. Get $50 off your first kit at TinyHealth.com/BEN. Timeline: Give your cells new life with Mitopure, which unlocks a precise dose of the rare Urolithin A molecule to promote healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN. JOYMODE: Spice things up in the bedroom and boost your sexual performance naturally, without prescription drugs. Visit tryjoymode.com/BEN or enter BEN at checkout for 20% off your first order. Supzential: More Than a Toothpaste: Created by biological dentist Dr. Dome, it combines bioavailable hydroxyapatite, a patented probiotic, xylitol, and lactoferrin to support enamel remineralization and a healthy oral microbiome, with no fluoride, SLS, or titanium dioxide. Visit Supzential.com and use code BEN20 for 20% off. BIOptimizers Magnesium Breakthrough: Seven essential forms of magnesium in one full-spectrum serving to help you relax, unwind, and sleep deeply so you wake up refreshed. Go to bioptimizers.com/ben and use code ben15 for 15% off any order. See omnystudio.com/listener for privacy information.

Full show notes: https://bengreenfieldlife.com/504 In this solosode, you'll get the latest research on three questions I keep getting asked. First, seed oils: a brand-new randomized controlled trial put 52 adults on either a low or a typical Western intake of linoleic acid for 12 weeks, and the results are important less for what they found than for what they didn't. You'll hear why arachidonic acid didn't move, why EPA dropped instead, what that does to your inflammatory balance, which seed oils I still think are worth avoiding, and the one dietary adjustment that matters most if seed oils are part of your diet. You'll also learn the surprisingly small amount of strength training that delivers the biggest longevity payoff, according to a 30-year study of more than 147,000 people, plus why pairing it with cardio is the single best exercise combination for blood pressure. I break down concurrent training, the interference effect between AMPK and mTOR, and when combining strength and cardio in one session helps you versus when it holds you back. Finally, I answer a listener question on peptides with six practical rules for stacking them safely, including which ones should never share a syringe, which ones cancel each other out at the receptor, and an honest look at how thin the human evidence really is behind the popular Wolverine stack. Episode Sponsors: Young Goose: Cutting-edge skincare that supports your skin's cellular health. Visit younggoose.com and use code BGF10 for 10% off. ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, without the jitters or crash. Visit takeultra.com and use code BENGREENFIELD for 15% off. ButcherBox: Premium, responsibly sourced protein delivered to your door, from 100% grass-fed beef to pasture-raised chicken and wild-caught seafood. New customers get a free protein for a year, plus $20 off the first box and free shipping, at ButcherBox.com/BEN. Larine: A better-for-you chewing gum that uses nano-hydroxyapatite, the same mineral your tooth enamel is made of, to support stronger teeth and fresher breath. Visit BuyLarine.com/BEN to get up to 50% off your order. Nuchido: Nuchido TIME+ is a science-backed supplement that optimizes your body's NAD metabolism across multiple pathways to support energy, cognition, recovery, and vitality. Visit BenGreenfieldLife.com/Nuchido and use code BEN20 to save 20%. See omnystudio.com/listener for privacy information.