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Malaria kills around 600,000 people every year. Nearly three-quarters of those deaths are children under five. For decades, scientists pursued one goal: a vaccine that could prevent the disease. One scientist dedicated his career to this challenge. Sir Adrian Hill of the University of Oxford set out to develop a vaccine that could save lives where it was needed most... Like this podcast? Please help us by supporting the Naked Scientists

In this special episode, created in partnership with the Royal Institute of Navigation, we hear from Alex Stewart. Alex is a founding engineer at Oxa, a leading autonomous vehicle (AV) technology company in Oxfordshire, England, and he has spent the past twenty years developing advanced autonomous systems. He recently told Chris Smith about Oxa's vision for transforming how goods move... Like this podcast? Please help us by supporting the Naked Scientists

This time, macho male gorillas trade stature for sperm count, how gambling machines use sound and light to take the sting out of losing, whether babies are born hard-wired to dance, the way bird eggs are adapted to altitude, and the effect of a fever on the stickiness of malaria-infected blood cells... Like this podcast? Please help us by supporting the Naked Scientists

Malaria has been killing humans for at least fifteen thousand years, and our DNA still carries the scars. Ninety percent of the world's malaria cases are in Africa. But this isn't just a modern health crisis. It's written into our evolutionary history. New research from the University of Cambridge reveals that early humans actively avoided malaria hotspots across Africa for tens of thousands of years. The archaeological record is striking: mosquitoes thrived where people didn't live. Until something changed. Around fifteen thousand years ago, a genetic mutation emerged in West Africa: the... Like this podcast? Please help us by supporting the Naked Scientists

Africa remains at the centre of the global malaria crisis. The continent accounts for around 95 percent of all malaria cases, placing immense strain on health systems and costing hundreds of thousands of lives each year. In 2023, there were an estimated 249 million cases globally, with the vast majority in sub-Saharan Africa. So why does malaria persist so strongly here? Like this podcast? Please help us by supporting the Naked Scientists

A child dies from malaria roughly every minute. A stark reminder of why urgent action is still needed. "Driven to end malaria, now we can, now we must" is the theme of World Malaria Day on the 25th of April. This year also marks 25 years of the Johns Hopkins Malaria Research Institute, which has shaped modern malaria control strategies. In this episode, we hear from Ashley Birkett, Global Head of Bacterial and Parasitic Diseases at PATH Center for Vaccine Innovation and Access... Like this podcast? Please help us by supporting the Naked Scientists

In this episode, how kangaroos alter their postures to store more energy in their Achilles tendons and boost movement efficiency, the moths that make a beeline when they hear plants "talking" to them, tracking how people pick up diseases from their surroundings, the contribution fingerprints make to touch sensation, and some forgotten female scientists are recognised at the Eiffel Tower, in France. Like this podcast? Please help us by supporting the Naked Scientists

This month, compelling evidence for why some species keep their eyes closed for sometimes several weeks after birth, scientists prove that the "nocebo" effect is more potent than a placebo, researchers report what happens when fish eggs and mouse sperm mix, the signals that cells use to measure the lengths of their telomeres, and some clever physics reveals the workings of Darwin's "warm little pond"... Like this podcast? Please help us by supporting the Naked Scientists

Clots in our blood vessels can be responsible for very serious health problems such as strokes and heart attacks. To combat this, some people at risk of said health problems turn towards blood thinners to prevent this clotting, with the most common household blood thinner being aspirin. The issue with preventing clotting is, should you start to bleed, that bleeding is a lot tougher to stop. Now however, a new drug - clopidogrel - is being touted as coming with the same benefits of aspirin, but few of the drawbacks. To talk us through this matchup, we put in a call to the British Heart... Like this podcast? Please help us by supporting the Naked Scientists

Peter Cowley was an entrepreneur, angel investor, and for many years was the Naked Scientists technology commentator, a role he fell into by accident when we met one evening at an investment meeting. He became a good friend. But his life, in many respects, despite being incredibly successful, was also touched by great sadness: he lost two sons and struggled with alcohol for a time. But he came through it all and lived his life with energy, curiosity, and generosity... Like this podcast? Please help us by supporting the Naked Scientists

With only a few walls between an astronaut and a rapid death, what do we know about the various dangers to the human body during space travel? Chris Smith spoke with Mark Shelhamer, a professor of Otolaryngology - Head and Neck Surgery at John Hopkins Medical School - about which space hazards are deemed most pressing for our up-and-coming astronauts... Like this podcast? Please help us by supporting the Naked Scientists

This month, as the eLife Podcast hits its century, we hear how getting frog dads to cross-foster tadpoles has revealed the way in which some frogs come by their microbiomes, the ants that do gene therapy, signs that disease causes a breakdown in nutrient exchange between the elements of the microbiome, how fungi reprogram immune cells to cause over-reactions in sepsis, and new insights into how tapeworm larvae in the brain cause seizures... Like this podcast? Please help us by supporting the Naked Scientists

As the global population heads toward 10 billion, the pressure on agriculture is mounting. With that in mind, the UK's Advanced Research and Invention Agency (ARIA) has announced millions of pounds worth of funding for crops enhanced through synthetic biology by designing entirely new chromosomes and chloroplasts, starting with the potato, as Angie Burnett, the ARIA Programme Director and plant biologist leading this initiative explains to Marushka Soobben... Like this podcast? Please help us by supporting the Naked Scientists

"Warp speed, Mr Sulu." It's the kind of command we've only heard in science fiction - until now. Did a team of scientists just bend spacetime using nothing but sparks in a lab? That's right - not black holes, not neutron stars - electrical sparks. A new experiment claims to have created tiny ripples in the very fabric of space and time, right here on Earth. If it holds up, it could be the first step toward technologies once thought possible only in science fiction: warp drives, fusion reactors, even medical time control. But is it the real deal - or just a very flashy illusion? I sat down with... Like this podcast? Please help us by supporting the Naked Scientists

In the eLife podcast, a university compost heap has turned up Finland's first documented "giant virus". Also, why monkeys de-sand their supper, and how learning more languages actually makes brain tissue thinner. Then, the link between sugar and neonatal sepsis, and how a cancer controls its hydra host by bestowing it with extra tentacles... Like this podcast? Please help us by supporting the Naked Scientists