
Advertise on podcast: Serious Inquiries Only
Rating
4.6from
This podcast has
843 episodes
Language
EnglishPublisher
seriouspod.comExplicit
Yes
Date created
2014/01/21
Latest episode
2026/09/15
Average duration
57 min.
Release period
9 days
Description
Join Thomas for some critical thinking on questions of science, philosophy, skepticism and politics. These serious topics are discussed with some serious guests, but in an entertaining and engaging way! This is not your typical interview podcast; it's a friendly dialogue, conducted thoughtfully and with plenty of humor. It's Serious Inquiries Only; but like, not boring or anything.
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Podcast episodes
Check latest episodes from Serious Inquiries Only podcast
SIO527: The Science of Why We Ask Why, with Dr. Tania Lombrozo
2026/09/15
Dr. Tania Lombrozo, professor of psychology at Princeton University (affiliated with its philosophy and cognitive science departments), joins Thomas to discuss her forthcoming book Why We Ask Why: The Science of Explanation and the Human Drive to Understand.
Why are humans so driven to explain things, but only some things? Why does understanding go beyond just being able to predict? And what happens when asking why makes you the social liability in the room?
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO526: Why Is College So Expensive?
2026/09/01
David O'Brien, higher education policy scholar with the California Community Colleges System, is back to answer the question Thomas posed last time: why is college so expensive?
They get into tuition vs. total cost of attendance, the dirty little secret of private university pricing, administrative bloat, the amenities arms race, and why the people loudest about college costs are likely well-off, but getting very little financial aid.
Mentioned:
The Daily: College, Student Loans, and Trump
Sara Goldrick-Rab's research on college costs and student basic needs
Cal Grant program (California)
Pell Grant
Americans with Disabilities Act
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
Some More News Is COMPLETELY WRONG About Spider-Man Brand New Day
2026/08/31
I cannot stop thinking about Cody from Some More News's video in which he could not stop thinking about Spider-Man: Brand New Day. Cody is INCREDIBLY sure that you're an idiot incapable of watching movies or consuming art if you don't agree with his conception of what the ending of Brand New Day meant. The problem is... Cody gets about a billion things wrong and his arguments are terrible.
This was going to be just a Patreon bonus of Serious Inquiries Only but I wanted to put it up on YouTube so it's going out to everyone! WATCH HERE!
Cody's video: "How Did Everyone Become So Bad at Watching Movies"
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO525: Dude Who Said Autism Is "Extreme Male Brain" Walks It Back
2026/08/11
... and other autism/ADHD research! So pleased to have Dr. Jenessa Seymour back - this time with a variety of studies in the Autism and ADHD realms.
Jurek, L., Duchier, A., Gauld, C., Henault, L., Giroudon, C., Fourneret, P., … Nourredine, M. (2025). Sensory processing in individuals with Attention-Deficit/Hyperactivity Disorder compared with control populations: A systematic review and meta-analysis. Journal of the American Academy of Child & Adolescent Psychiatry, 64, 1132-1147.
Le Cunff, A., Russell, C. & Dommett, E.J. (2026). Hyperactive–impulsive ADHD traits predict
Higher curiosity in adults: evidence from a cross-sectional study. BMC Psychology, 14, 1-11.
White, R.C. & Remington, A. (2018). Object personification in Autism: This paper will be very sad if you don't read it. Autism, 23, 1042-1045.
Botha, M. & Cage, E. (2022). "Autism research is in crisis": A mixed method study of researcher's constructions of autistic people and autism research. Frontiers in Psychology, 13, 1-22.
Devlin, H. (July 5, 2026). Pioneer of 'extreme male brain' theory of autism now says phrase unhelpful. The Guardian.
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO524: Why We Haven't Cured Cancer Yet, Part 2 (with Dr. Eric Jaffe)
2026/07/29
Part 2! Dr. Eric Jaffe returns to actually treat the cancer this time: why radiation is basically catching your kid smoking and making him finish the carton, how CRISPR turns your own T cells into an assassin squad, and why oncolytic viruses are just Jurassic World Dominion for tumors.
Haven't heard Part 1 yet? Start there or you'll be lost.
Mentioned:
CAR-T therapy
RAS inhibitor drugs
Oncolytic viruses
mRNA cancer vaccines
Red Queen hypothesis
Cancer-sniffing dogs
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO523: What Cancer Actually Is, Part 1 (with Dr. Eric Jaffe)
2026/07/28
Part 1! Dr. Eric Jaffe, the biology teacher who keeps naming proteins after cartoon characters, returns for a two-part cancer deep dive. Today: what cancer actually is at the cellular level, why elephants barely get it, why whales get it even less, and why the "they're hiding the cure" conspiracy falls apart the second you learn who actually funds the research.
Mentioned:
Peto's paradox
HeLa cells
The Immortal Life of Henrietta Lacks
XKCD cancer comic
Part 2, the cure, is already up for Patreon supporters!
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO522: College Is Impossibly Expensive. But It's Not Because of Bogus Degrees.
2026/07/21
Part 2! Thomas is joined again by David O'Brien, a higher education policy scholar with the California Community Colleges system, to finish dismantling The Daily's take on Trump's student loan crackdown. Reagan, Pell Grants, and decades of quiet state defunding all get their due, plus a theory on why tuition keeps climbing that has nothing to do with cosmetology degrees.
Mentioned:
The Daily college episode
Gainful employment rules
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO521: The Daily Is Sane-Washing Trump's War on Higher Ed
2026/07/21
Thomas is joined by David O'Brien, a higher education policy scholar who works for the California Community Colleges system, to pick apart Trump's new rules threatening to cut off student loans and Pell grants from "low-earning" degree programs, and to fact-check The Daily's recent take on the same story. The real history runs through Reagan, Prop 13, and decades of quiet austerity nobody on that podcast wants to mention.
Mentioned:
The Daily college episode
Reagan 1966 campaign clip
Prop 13
CUNY tuition history
California Master Plan for Higher Education
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO520: My Talk at SkeptiCal - Selective Skepticism Is Not Skepticism
2026/06/30
Thanks so much to the folks at SkeptiCal for inviting me! Though the talk does deal with the Butler shooting, I thought some way different stuff for this including a ridiculously overwrought hypothetical, my favorite kind! And, I found a Young Turks video where they are apparently Joe Rogan now!
SIO519: People Are Misinterpreting Obsession in Very Revealing Ways
2026/06/24
The "nice guy" is the villain. We watched Obsession and cannot stop thinking about it. It has so much to say about gender, consent, "nice guys" and more. And it scarred Lydia for life.
WARNING: CONTAINS SPOILERS.
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO518: Biological Definitions Do Not Do What Richard Dawkins Says They Do
2026/06/16
Thomas is joined by Dr. Eric Jaffe, biologist, dinosaur enthusiast, and high school biology teacher, for a conversation that starts with a deceptively simple question: what are biological definitions actually doing?
It turns out that biology is far more like history than math, and that difference has enormous consequences for anyone trying to weaponize phrases like "the biological definition of sex." Dr. Jaffe walks through why definitions in inductive sciences are descriptive, not prescriptive, and what that means for species, chromosomes, fungi, LeBron James, and trans people.
"Exceptions aren't the exceptions in biology. They are built into what we call biological systems."
Plus: Patreon Q&A questions on alien DNA, how new chromosomes evolve, the 97% chimp figure, CRISPR vs. what came before, and Trump's research budget cuts.
Cells at Work (anime recommended by Dr. Jaffe)
Project Hail Mary (film referenced)
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO517: How Is It That 9 Days in Space Means Weeks of Rehabilitation?
2026/06/09
Thomas is joined by Dr. Jenessa Seymour to dig into the brain science behind a surprisingly strange phenomenon: why do astronauts who spent just nine days in space need weeks of physical therapy to walk normally again?
The answer turns out to involve ancient calcium carbonate ear stones, the same material crabs use for shells, a multi-layered sensory system your brain is constantly running without your knowledge, and a wild evolutionary theory about why motion sickness exists at all. Also: why pilots fly perfectly good planes directly into the ground, and what deaf NASA research participants revealed about how proprioception actually works.
Come see me at SkeptiCal!
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO516: How a Botched 1840 Census "Proved" Freedom Made Black Americans Disabled, with Sari Altschuler
2026/05/31
The history of disability rights is often treated as a modern story, but what if that framing misses centuries of earlier, more complicated history? This week, Thomas is joined by Professor Sari Altschuler, Associate Professor of English at Northeastern University, to explore her new book Before Disability: A History of American Citizenship.
In the book, Professor Altschuler traces how disability and citizenship have been intertwined since the founding of the United States, and what that reveals about who America decided belonged and who didn't. In the early Republic, many physical and mental differences were accommodated within the framework of citizenship; by the antebellum era, however, those same differences had been weaponized as tools of racial exclusion, and eventually as justification for eugenics.
Thomas and Professor Altschuler dig into the intersections of race, disability, and civic belonging, and what early American history can teach us about the fights happening today.
Be sure to buy Before Disability: A History of American Citizenship (release date: 6/16/2026)!
Touch This Page! Making Sense of the Ways We Read
Are you an expert in something and want to be on the show? Apply here!
Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content! https://www.patreon.com/seriouspod
SIO515: A Vast, Global Network! ... of 3 Guys
2026/05/18
Continuing the discussion of the CNN Rape Academy article. It gets even worse. And also, how our information environment is ruined and getting ruineder.
SIO514: No Part of the "62 Million Men Enrolled In Online Rape Academy" Claim Was Correct
2026/05/18
You might have seen the CNN article from a while back entitled Exposing a global 'rape academy'. While most of the article is technically true, the broad takeaway that virtually everyone had (including me) was wildly, irresponsibly false.
Even if you came across debunks of this, there's a good chance that I'm debunking this even more than you've seen. I don't think people have fully grasped how misleading it was.
Podcast reviews
Read Serious Inquiries Only podcast reviews
loving the podcast 2025/02/07
If you care about reality, listen to this podcast!
Thomas has always delivered sharp thoughtful analysis but his latest batch of episode since the election has been on fire! If you recognize what’s hap...
IcenineCC 2025/01/22
Great show
Thomas is awesome
Talkahuano 2025/01/12
Please stop talking about Trump
I thought this podcast was for learning about jobs and cool sciency stuff. Why is it political now? Other podcasts from the same guy already do that. ...
Cat Mom 103 2024/11/09
Clarity
Thank you for your clarity, I appreciate you.
BG45 2024/10/12
Ads Only
How do you know it’s a Thomas Smith podcast? It has 4x the ads of any other podcast you listen to.
OutdoorKatnip 2024/08/29
A fun way to learn a little bit about a lot
Thomas is one of my all-time favorite podcast hosts. Versatile, entertaining, and a great question asked. He knows right when to pop in with a humorou...
Agapic64 2024/08/01
Unserious
Not very serious. Name calling, poor grammar and spelling. Talking points mixed with poor research. Appeals to authority. Unfollowing.
izzybr 2024/01/31
Great podcast if you’re already of limited intellectual capacity
If you are more intelligent than a clever jellyfish, I’m not sure this podcast is for you. If you perhaps are an amoeba with fetal alcohol syndrome, t...
goodvsevil 2024/01/12
I politely disagree
We MIGHT live in a "simulation" of sorts; if it is computer based, it isnt like any kind of computer that we can imagine right now. And the simulated...
Grand Priapism 2023/11/08
Thomas makes everything better. Lydia "assists"
Thomas is the grease that makes the podcast go. He's the interested comedian or whatever they used to say on that other podcast. Lydia and Thomas are ...
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