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Ellie and Lucy kick off the season and introduce our new executive buzzer, Melita! Melita is a masters student in statistics at Wake Forest University and will be helping out with the podcast (and keeping Lucy and Ellie from using too much jargon!) Pros & Cons of RCT paper:  Fernainy, P., Cohen, A.A., Murray, E. et al. Rethinking the pros and cons of randomized controlled trials and observational studies in the era of big data and advanced methods: a panel discussion. BMC Proc 18 (Suppl 2), 1 (2024). https://doi.org/10.1186/s12919-023-00285-8 Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Cameron Bopp

We are re-releasing an episode from 2021 in remembrance of Ralph D'Agostino, Sr.  Ellie Murray and Lucy D’Agostino McGowan chat with Ralph D’Agostino Sr. and Ralph D’Agostino Jr. about their careers in statistics, looking back at how things have developed and forward at where they see the world of statistics and epidemiology going.  Ralph D’Agostino Sr. was a professor of Mathematics/Statistics, Biostatistics, and Epidemiology at Boston University. He was the lead biostatistician for the Framingham Heart Study, a biostatistical consultant to The New England Journal of Medicine, an editor of Statistics in Medicine and lead editor of their Tutorials, and a member and consultant on FDA committees. His major fields of research were clinical trials, prognostic models, longitudinal analysis, multivariate analysis, robustness, and outcomes/effectiveness research.  Ralph D’Agostino Jr. is a professor in the Department of Biostatistics and Data Science at Wake Forest University where he is the Director of the Biostatistics Core of the Comprehensive Cancer Center. Methodologically his research includes developing statistical techniques for evaluating data from observational settings, handling missing data in applied problems, and developing predictive functions to identify prospectively patients at elevated risk for future negative outcomes. Some of his recent work includes the development of methods using propensity score models to identify safety signals in large retrospective databases. 

Ellie and Lucy chat with Dr. Cat Hicks, VP of Research Insights and Director of Developer Success Lab at Pluralsight Flow, about evidence science.    Follow along on Twitter: Cat: @grimalkina The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat about a "Causal Quartet" and spend some extra time on M-Bias!   Lucy, Travis, & Malcom's Causal Quartet Paper Lucy's quartets R package Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat about ENAR 2023 and Targeted Learning! Targeted Learning in R Handbook Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat with #EpiCookieChallenge winner, Viktoria Gastens! Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Viktoria: @VikiGastens Viktoria's Lab: @PopHealthLabCH Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat about confounding! ✍️ Lucy's new paper: Sensitivity Analyses for Unmeasured Confounders Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat about randomized controlled trials, thinking about efficacy vs effectiveness and saftey vs safetiness. ✍️ Frank Harrell's blog post "Randomized Clinical Trials Do Not Mimic Clinical Practice, Thank Goodness" Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat with Maria Glymour, Professor of Epidemiology & Biostatstics at UCSF and incoming chair of the Department of Epidemiology at Boston University. Maria successfully convinces Ellie and Lucy that instrumental variables can be very useful in epidemiology.  Follow up: ✍️ Andrew Heiss's blog post on marginal and conditional effects for GLMMs Follow along on Twitter: Maria Glymour: @MariaGlymour The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat about critiquing methods research, average treatment effects, and positivity violations! Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade

Lucy D'Agostino McGowan and Ellie Murray chat with Travis Gerke, Director of Data Science at The Prostate Cancer Clinical Trials Consortium (PCCTC). This episode has lots of hot takes and lots of love for logistic regression! Follow along on Twitter: Travis Gerke: @travisgerke The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com

Lucy D'Agostino McGowan and Ellie Murray chat about counterfactuals! Follow along on Twitter: The American Journal of Epidemiology: @AmJEpi Ellie: @EpiEllie Lucy: @LucyStats 🎶 Our intro/outro music is courtesy of Joseph McDade Edited by Quinn Rose: aspiringrobot.com