
Advertise on podcast: Core IM | Internal Medicine Podcast
Rating
4.8from
This podcast has
229 episodes
Language
EnglishPublisher
Core IM TeamExplicit
No
Date created
2017/10/17
Latest episode
2026/10/21
Average duration
30 min.
Release period
12 days
Description
Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges
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Check latest episodes from Core IM | Internal Medicine Podcast podcast
#221 Colon Cancer Screening After Age 75 | 5 Pearls Segment Part 3
2026/10/21
“Should you stop screening for colorectal cancer (CRC) at 75?”
This episode explores how to individualize screening decisions based on life expectancy, prior colonoscopy findings, and procedural risks. Learn how to navigate these nuanced conversations, avoid age-based assumptions, and use strategies like mailed FIT kits and offering screening choices to help more patients get screened.
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🔹Transcript and Show Notes
01:18 | Screening >75 yo?
10:06 | Takeaways on Colorectal Cancer Screening After 75
10:37 | Systems thinking: How do we get to an 80% screening rate
Tags: Core IM, Internal Medicine, Colorectal Cancer Screening, Gastroenterology, Cancer Screening
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#220 Colon Cancer Screening Nuances: 5 Pearls Segment Part 2
2026/10/08
“What’s the best way to screen?” This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right CRC screening option for your patients. Also learn practical colonoscopy surveillance intervals based on polyp size, number, and pathology.
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🔹Transcript and Show Notes
01:24 | Screening Options Besides Colonoscopy
11:22 | How FIT, FIT-DNA, and CT colonography differ and when each makes sense.
12:52 | Colonoscopy and Frequency
19:29 | How adenoma number, size, and histology guide surveillance intervals.
Tags: Core IM, Internal Medicine, Colorectal Cancer Screening, Gastroenterology, Cancer Screening
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#219 Updates in Triglycerides
2026/09/29
“The triglycerides are high. Now what?” This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to suspect an underlying genetic disorder.
🔹Transcript and Show Notes
02:17 | Check a non-HDL-C or ApoB if TGs are ≥150 mg/dL
07:18 | Address waist circumference and lifestyle before meds for high TGs
10:52 | Dr. Watson’s 3-day carbohydrate responsiveness trial
17:07 | Order a fasting or nonfasting lipid panel?
19:00 | When do you reach for TG-lowering medications?
25:26 | Familial chylomicronemia syndrome (FCS)
Tags: CoreIM, Medical Education, Hypertriglyceridemia, ACC AHA lipid guidelines, lipid guidelines 2026, cardiovascular risk
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#218 Early-Onset Colon Cancer: 5 Pearls Segment Part 1
2026/09/23
“Too young for colon cancer.” This episode unpacks the red flags of early-onset colorectal cancer (CRC), from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and offers practical pearls for closing the clinical loop. Also learn why a “negative” family history may need a yearly refresh.
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🔹Transcript and Show Notes
01:45 | Colorectal cancer rising in younger adults
06:42 | Why screening starts at age 45
08:15 | What may be driving early-onset colorectal cancer
13:37| Key takeaways: symptoms, follow-up, and family history
Tags: Colorectal Cancer Screening, Internal Medicine, Gastroenterology, Cancer Screening, Oncology
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#217 Treatment for Alcohol Use Disorder: 5 Pearls Segment
2026/09/16
“It didn’t work.” This episode breaks down practical treatment options (dosing options for naltrexone, acamprosate, topiramate, gabapentin) and counseling pearls to help you meet patients where they are and support their recovery. Also discover blind spots in detox and rehab centers.
🔹Transcript and Show Notes
🔹 Explore ACP’s Substance Use Disorder Education Hub for videos and an AI-powered patient simulation to practice alcohol-use conversations: https://www.coreimpodcast.com/SUDhub
Alcohol Use and Chronic Health Conditions Mini Video Series
01:55 | #1: Naltrexone
12:06 | #2 Acamprosate
16:15 | #3: Topiramate
21:12 | #4: Other meds
29:31 | #5: Detox and rehab blind spots
Tags: CoreIM, Medical Education, Addiction Medicine, Alcohol Withdrawal, Addiction Treatment, GLP-1, pharmacology
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#216 Clinician Grief: At the Beside Segment
2026/09/08
Have you ever lost a patient and found yourself thinking about them long after the shift ended? This episode explores the grief clinicians can carry after a patient dies, including the losses that aren’t always obvious. We also discuss ways to work through that grief, recognize when it becomes complicated, and lean on your team for support.
🔹Transcript and Shownotes
04:12 | What is Clinician Grief?
10:02 | Types of Losses
10:22 | Loss of a close relationship with a particular patient
12:56 | Loss due to a professional's identification with the pain of family members
13:56 | Loss of one's unmet goals and expectations and one's professional self-image and role
18:47 | Loss related to one's personal system of beliefs and assumptions about life
21:30 | Past unresolved losses or anticipated future losses
23:29 | The death of the self
25:44 | Coping
Tags: CoreIM, Medical Education, Clinician Wellbeing, Burnout, Secondary Traumatic Stress, Complicated Grief, Coping With Grief, Medical humanities, medical ethics
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#215 Gallbladder & Biliary Testing: 5 Pearls Segment
2026/08/25
How to choose between RUQ ultrasound, CT, HIDA, MRCP, EUS, and ERCP based on the clinical picture? When should you move from diagnostic imaging to therapeutic ERCP, and what should you know about sphincterotomy, stents, and stone removal? Plus, how to interpret bile duct dilation without jumping straight to obstruction?
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🔹Transcript and Shownotes
02:11 | Pearl 1: Gallbladder Problems Spectrum
07:33 | Pearl 2: Choose Imaging Strategically: Start with RUQUS, Escalate as Needed
14:34 | Pearl 3: Biliary Tree Diagnostics
19:19 | Pearl 4: Invasives that are Diagnostic and Therapeutic
27:06 | Pearl 5: Stenting in ERCP
Tags: CoreIM, Internal Medicine, Medical Education, Gallstones, Cholecystitis, Biliary Disease, ERCP, Biliary Imaging
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#214 Hyponatremia Management: A Core IM Classic
2026/08/12
Throwback: Should you really fluid-restrict every patient with SIADH? When can IV fluids make hyponatremia better or worse? Are salt tabs actually doing enough? And what can urine studies tell you before you start treatment? Join us for a practical, physiology-driven approach to hyponatremia management, from fluids and solutes to loop diuretics and identifying the underlying cause.
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🔹Transcript and Shownotes
6:46 | Pearl 1: Key Principles
15:13 | Pearl 2: Fluids in hyponatremia
26: 03 | Pearl 3: Solutes in hyponatremia management
35:49 | Pearl 4: Lasix in hyponatremia management
40:05 | Pearl 5: Etiologies
Tags: CoreIM, Internal Medicine, Medical Education, SIADH, Fluid Restriction, Nephrology, Hospital Medicine, Urine Osmolality
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#213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series
2026/07/28
Why can lower-dose combinations be more effective and better tolerated than maximizing one medication? How to troubleshoot common challenges such as amlodipine edema, gout, electrolyte abnormalities, and the patient who says they cannot tolerate anything? Why ACT (ARBs, Calcium Channel Blockers, Thiazides) is the preferred first-line framework, and how to personalize medication choices based on comorbidities and side effects.
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🔹Transcript and Shownotes
03:00 | Diagnosing Hypertension
04:10 | When to Start Combination Therapy Instead of Monotherapy
07:00 | Choosing First-Line Therapy Using the ACT Framework
13:23 | Why ARBs Are Often Preferred Over ACE Inhibitors
16:02 | Choosing the Right ARB: Candesartan vs Losartan
18:39 | Comparing Potency & Duration Across First-Line Antihypertensives
20:54 | Amlodipine Edema: Why It Happens and How to Fix It
23:54 | Thiazides: Practical Tips, Electrolyte Problems & Class-Killer Side Effects
29:33 | Managing Patients Who 'Can't Tolerate' Blood Pressure Medications
Tags: Hypertension Management, High Blood Pressure, Primary Care, Internal Medicine, Core IM
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#212 Top 10 Highlights of the New Lipid Guidelines
2026/07/15
Learn from primary care docs what has been practiced and changed from the 2026 ACC/AHA Lipid Guidelines! Learn how the new CPR framework (Calculate, Personalize, Reclassify) and PREVENT risk calculator change statin decisions, why LDL targets are back, and when to use Lp(a), ApoB, and coronary artery calcium (CAC) testing. Discover updated risk-enhancing factors, expanded indications for non-statin therapies, and practical strategies to personalize lipid management for both primary and secondary
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🔹Transcript and Shownotes:
01:17 | Highlight #1 & #2: CPR and PREVENT Score
03:14 | Highlight #3: Updated ASCVD Risk Categories Using the PREVENT Score
05:30 | Highlight #4: LDL Targets Are Back
07:20 | Highlight #5: High-Risk Conditions That Bypass the PREVENT Score
08:41 | Highlight #6: Lp(a) Screening for Everyone
11:51 | Highlight #7: When to Use ApoB Testing
13:16 | Highlight #8: Reproductive Risk Factors
15:29 | Highlight #9: Using CAC to Guide Statin Therapy
19:09 | Highlight #10: Non-Statin Therapies
Tags: CoreIM, Internal Medicine, Medical Education, Cholesterol, Statins, LDL, ASCVD, Preventive Cardiology, LpA, ApoB, CAC, ACC2026, Cardiology, PrimaryCare
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#211 Breaking Down MASLD vs. MASH and the MAESTRO-NASH & ESSENCE Trials: Beyond Journal Club Segment
2026/06/29
MASLD affects nearly one in three adults worldwide, yet many patients remain undiagnosed until advanced fibrosis or cirrhosis develops. So, which patients should clinicians actually be screening? When is a FIB-4 enough, and when should we move to elastography or hepatology referral? And are we finally entering an era where we can meaningfully treat MASH?
In this Beyond Journal Club episode, we unpack the evolving language of steatotic liver disease and take a close look at two major trials: MAESTRO-NASH studying resmetirom, the first FDA-approved liver-directed therapy for MASH, and ESSENCE, evaluating semaglutide in biopsy-confirmed disease.
Along the way, we explore what these biopsy-based histologic endpoints really mean, why placebo responses were surprisingly high, and whether improvements in steatohepatitis and fibrosis will ultimately translate into better clinical outcomes for patients.
This episode is for clinicians trying to understand where the field is headed, which patients deserve closer attention, and how metabolic liver disease is increasingly becoming part of everyday primary care and hospital medicine.
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🔹Transcript and Shownotes:
01:57 | Understanding MASLD as a Systemic Disease
05:45 | MASLD vs MASH vs Met-ALD: Spectrum Steatotic Liver Disease
08:55 | How to Screen for Fibrosis (FIB-4 & FibroScan)
16:15 | Lifestyle Treatment & Weight Loss Targets
19:00 | ESSENCE Trial: Semaglutide for MASH
21:58 | MAESTRO-NASH Trial: Resmetirom
27:27 | Future Treatments for MASH
30:51 | Key Takeaways for Clinicians
Tags: CoreIM, Internal Medicine, Medical Education, Hepatology, Fatty Liver Disease, Metabolic Dysfunction Associated Steatohepatitis, Nonalcoholic Fatty Liver Disease, Liver Fibrosis
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#210 HTN in Dialysis: 5 Pearls Segment
2026/06/17
What blood pressure should we target in patients on hemodialysis? Why volume control remains the foundation of treatment? How blood pressure targets differ from the general population. Learn practical pearls on medication timing around dialysis, drug dialyzability, antihypertensive selection, and strategies to prevent intradialytic complications while optimizing long-term outcomes.
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🔹Transcript and Shownotes:
02: 19 | Pearl 1: Blood Pressure Targets
09: 40 | Pearl 2: Timing Medications and Dialyzability
15: 31 | Pearl 3 - Pharmacologic Management Nuances in Dialysis Patients
22: 57 | Putting It All Together: The Medication Hierarchy
Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, ESRD, End-Stage Kidney Disease, Hypertension, Kidney Health, Dry Weight, Volume Overload
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#209 Dialysis and Fluid Management: 5 Pearls Segment
2026/06/10
Why is fluid management the most important part of dialysis care? This episode explores the fundamentals of hemodialysis, why ESKD patients have unique physiology, and how volume overload, not just hypertension, drives many complications. Learn practical pearls on dry weight, sodium restriction, diuretics, and the strategies that can reduce hospitalizations and improve patient outcomes.
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🔹Transcript and Shownotes:
02:49 | Pearl 1: Foundations of Dialysis
09:21 | Pearl 2: Distinct Physiology
11:42 | Pearl 3: Why is fluid management so important?
19:43 | Pearl 4: Fluid Management Pro-tips
25:31 | Pearl 5: Diuretics in Patients with Residual Kidney Function
Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, Dialysis, End-stage kidney disease, Hypertension, Kidney Health, Dry Weight, Volume Overload
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#208 AI vs. Human with Post-Op AFib: Bread & Butter Series
2026/05/27
Can AI manage post-op atrial fibrillation or does medicine still require human judgment? Using post-op AFib as a case study, we explore where algorithms help, where evidence falls short, and why clinical context still matters. When evidence is incomplete, and every patient is different, can AI truly practice medicine or only assist the clinicians who do? This episode explores the space between algorithms, uncertainty, and human judgment in modern medical care.
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🔹Transcript and Shownotes:
02:51 | Broad workup for reversible causes and other etiologies of AFib that may occur post-op
05:10 | Considerations for management of post-op atrial fibrillation
13:00 | Stroke risk in atrial fibrillation
20:49 | Outpatient management of atrial fibrillation
25:54 | The role of AI in medical decision-making
Tags: CoreIM, Internal Medicine, Medical Education, Atrial Fibrillation, Cardiology, Open Evidence
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#207 Is There a Doctor on Board? In-Flight Emergencies
2026/05/18
We start with a gripping story of seizures and use it as a jumping-off point to unpack practical pearls for in-flight emergencies. Along the way: what’s actually in the emergency medical kit, when planes divert, how ground medical support works, altitude physiology, legal protections, and how to stay calm when medicine suddenly happens at 35,000 feet. By the end, you may still sweat a little…but hopefully less than before.
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🔹Transcript and Shownotes:
04:40 | Emergency Medical Kit (EMK) Standard Contents
08:50 | Role of Ground-Based Medical Support & Flight Diversion Decision-Making
19:35 | Interpreting Hypoxia at Altitude
22:06 | In-Flight Liability
23:35 | Common Chief Concerns & Useful Additional Medications
24:53 | How to Be Resourceful in an Austere Environment
Tags: CoreIM, Internal Medicine, Medical Education, In-flight Care, Medical Emergencies, Clinical Reasoning, Seizure Management, Hypoxia, Airway Management, Cardiac Emergency, Syncope, Respiratory Distress
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Podcast reviews
Read Core IM | Internal Medicine Podcast podcast reviews
MomCR2 2026/09/18
Great learning
Superb internal medicine podcast. Length is just right.
Dr Franco 2026/06/08
Best IM podcast
I subscribe to a lot of medical podcasts for internal medicine this is the best one in my opinion
IM Desert Doc 2026/05/29
Hits great topics - for all levels
Thank you for a great podcast. Hosts and guests are well-spoken and easy to understand. Topics are well thought out and relevant to clinical practice!
geridoc30 2026/05/29
Amazing
Love this podcast! Such an excellent review of important topics with extensive research to back it up. I love that they incorporate inter-professional...
Tyler5281 2026/05/25
Fantastic podcast
Podcast does a great job of providing high-yield , insightful clinical pearls. The information really helps me consolidate information I’ve learned el...
neworleansditty 2026/03/29
Skip the jokes
Good content, but no one is here for jokes, puns, attention-drawing references, self-satisfied quips etc. Your team's bright with useful info and org...
Lffhjd 2026/03/11
Has NP guests teaching MDs
Seriously misguided
joe11117 2026/02/12
Gold standard
Gold standard podcast for IM, med-peds or FM residents.
Futurebugdoc 2025/11/08
My go to learning tool
Been listening to CoreIM for the last 3 years. In my second year of residency now, and I recommend this to every med student, resident and attending I...
RUNBIKECOFFEEBEER 2025/05/17
Lp (a)
Thorough review and clear useful pearls on what it is and how to interpret and apply it.
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